Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome

Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with...
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Autor*in:	Alain Chebly [verfasserIn] Claudia Djambas Khayat [verfasserIn] Tony Yammine [verfasserIn] Rima Korban [verfasserIn] Warde Semaan [verfasserIn] Jessica Bou Zeid [verfasserIn] Chantal Farra [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	Acute myeloid leukemia AML Septin MLL SEPT6

Übergeordnetes Werk:	In: Leukemia Research Reports - Elsevier, 2015, 16(2021), Seite 100277-
Übergeordnetes Werk:	volume:16 ; year:2021 ; pages:100277-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.lrr.2021.100277

Katalog-ID:	DOAJ072185228

Internformat


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520			\|a Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases.
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spelling	10.1016/j.lrr.2021.100277 doi (DE-627)DOAJ072185228 (DE-599)DOAJ3751b9d1ef464ed5aecf299d32bc705e DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases. Acute myeloid leukemia AML Septin MLL SEPT6 Neoplasms. Tumors. Oncology. Including cancer and carcinogens Claudia Djambas Khayat verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Jessica Bou Zeid verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 16(2021), Seite 100277- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:16 year:2021 pages:100277- https://doi.org/10.1016/j.lrr.2021.100277 kostenfrei https://doaj.org/article/3751b9d1ef464ed5aecf299d32bc705e kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048921000443 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 16 2021 100277-
allfields_unstemmed	10.1016/j.lrr.2021.100277 doi (DE-627)DOAJ072185228 (DE-599)DOAJ3751b9d1ef464ed5aecf299d32bc705e DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases. Acute myeloid leukemia AML Septin MLL SEPT6 Neoplasms. Tumors. Oncology. Including cancer and carcinogens Claudia Djambas Khayat verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Jessica Bou Zeid verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 16(2021), Seite 100277- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:16 year:2021 pages:100277- https://doi.org/10.1016/j.lrr.2021.100277 kostenfrei https://doaj.org/article/3751b9d1ef464ed5aecf299d32bc705e kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048921000443 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 16 2021 100277-
allfieldsGer	10.1016/j.lrr.2021.100277 doi (DE-627)DOAJ072185228 (DE-599)DOAJ3751b9d1ef464ed5aecf299d32bc705e DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases. Acute myeloid leukemia AML Septin MLL SEPT6 Neoplasms. Tumors. Oncology. Including cancer and carcinogens Claudia Djambas Khayat verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Jessica Bou Zeid verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 16(2021), Seite 100277- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:16 year:2021 pages:100277- https://doi.org/10.1016/j.lrr.2021.100277 kostenfrei https://doaj.org/article/3751b9d1ef464ed5aecf299d32bc705e kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048921000443 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 16 2021 100277-
allfieldsSound	10.1016/j.lrr.2021.100277 doi (DE-627)DOAJ072185228 (DE-599)DOAJ3751b9d1ef464ed5aecf299d32bc705e DE-627 ger DE-627 rakwb eng RC254-282 Alain Chebly verfasserin aut Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases. Acute myeloid leukemia AML Septin MLL SEPT6 Neoplasms. Tumors. Oncology. Including cancer and carcinogens Claudia Djambas Khayat verfasserin aut Tony Yammine verfasserin aut Rima Korban verfasserin aut Warde Semaan verfasserin aut Jessica Bou Zeid verfasserin aut Chantal Farra verfasserin aut In Leukemia Research Reports Elsevier, 2015 16(2021), Seite 100277- (DE-627)738404586 (DE-600)2706248-X 22130489 nnns volume:16 year:2021 pages:100277- https://doi.org/10.1016/j.lrr.2021.100277 kostenfrei https://doaj.org/article/3751b9d1ef464ed5aecf299d32bc705e kostenfrei http://www.sciencedirect.com/science/article/pii/S2213048921000443 kostenfrei https://doaj.org/toc/2213-0489 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 16 2021 100277-
language	English
source	In Leukemia Research Reports 16(2021), Seite 100277- volume:16 year:2021 pages:100277-
sourceStr	In Leukemia Research Reports 16(2021), Seite 100277- volume:16 year:2021 pages:100277-
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Acute myeloid leukemia AML Septin MLL SEPT6 Neoplasms. Tumors. Oncology. Including cancer and carcinogens
isfreeaccess_bool	true
container_title	Leukemia Research Reports
authorswithroles_txt_mv	Alain Chebly @@aut@@ Claudia Djambas Khayat @@aut@@ Tony Yammine @@aut@@ Rima Korban @@aut@@ Warde Semaan @@aut@@ Jessica Bou Zeid @@aut@@ Chantal Farra @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	738404586
id	DOAJ072185228
language_de	englisch
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callnumber-first	R - Medicine
author	Alain Chebly
spellingShingle	Alain Chebly misc RC254-282 misc Acute myeloid leukemia misc AML misc Septin misc MLL misc SEPT6 misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome
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topic_title	RC254-282 Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome Acute myeloid leukemia AML Septin MLL SEPT6
topic	misc RC254-282 misc Acute myeloid leukemia misc AML misc Septin misc MLL misc SEPT6 misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RC254-282 misc Acute myeloid leukemia misc AML misc Septin misc MLL misc SEPT6 misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_browse	misc RC254-282 misc Acute myeloid leukemia misc AML misc Septin misc MLL misc SEPT6 misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome
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title_full	Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome
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author_browse	Alain Chebly Claudia Djambas Khayat Tony Yammine Rima Korban Warde Semaan Jessica Bou Zeid Chantal Farra
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title_sort	pediatric m5 acute myeloid leukemia with mll-sept6 fusion and a favorable outcome
callnumber	RC254-282
title_auth	Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome
abstract	Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases.
abstractGer	Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases.
abstract_unstemmed	Acute myeloid leukemia (AML) patients with MLL-SEPT6 fusion represent a small subset of AML. The uncommon MLL-SEPT6 rearrangement results from t(X;11) or other variants like ins(X;11), and it is usually associated with complex cytogenetic abnormalities. We herein report a case of AML-M5-infant with ins(X;11)(q24;q23q13) and MLL-SEPT6. The one-year-old boy presented with leukocytosis, anemia and thrombocytopenia. He had a favorable response to chemotherapy according to ELAM02protocol and is currently in complete remission. We here, highlight the occurrence of MLL-SEPT6 as the sole abnormality in a pediatric-AML-M5 case, discuss the prognostic implication of this genetic variant, while reviewing previously reported AML-MLL-SEPT6 cases.
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title_short	Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome
url	https://doi.org/10.1016/j.lrr.2021.100277 https://doaj.org/article/3751b9d1ef464ed5aecf299d32bc705e http://www.sciencedirect.com/science/article/pii/S2213048921000443 https://doaj.org/toc/2213-0489
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Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome

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