Bacteriophage-Delivering Hydrogels: Current Progress in Combating Antibiotic Resistant Bacterial Infection

Antibiotic resistance remains as an unresolved global challenge in the health care system, posing serious threats to global health. As an alternative to antibiotics, bacteriophage (phage) therapy is rising as a key to combating antibiotic-resistant bacterial infections. In order to deliver a phage t...
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Autor*in:	Hyun Young Kim [verfasserIn] Rachel Yoon Kyung Chang [verfasserIn] Sandra Morales [verfasserIn] Hak-Kim Chan [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	bacteriophage (phage) hydrogel multidrug-resistant bacteria formulation efficacy safety

Übergeordnetes Werk:	In: Antibiotics - MDPI AG, 2013, 10(2021), 2, p 130
Übergeordnetes Werk:	volume:10 ; year:2021 ; number:2, p 130

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/antibiotics10020130

Katalog-ID:	DOAJ072679298

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author	Hyun Young Kim
spellingShingle	Hyun Young Kim misc RM1-950 misc bacteriophage (phage) misc hydrogel misc multidrug-resistant bacteria misc formulation misc efficacy misc safety misc Therapeutics. Pharmacology Bacteriophage-Delivering Hydrogels: Current Progress in Combating Antibiotic Resistant Bacterial Infection
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topic_title	RM1-950 Bacteriophage-Delivering Hydrogels: Current Progress in Combating Antibiotic Resistant Bacterial Infection bacteriophage (phage) hydrogel multidrug-resistant bacteria formulation efficacy safety
topic	misc RM1-950 misc bacteriophage (phage) misc hydrogel misc multidrug-resistant bacteria misc formulation misc efficacy misc safety misc Therapeutics. Pharmacology
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title	Bacteriophage-Delivering Hydrogels: Current Progress in Combating Antibiotic Resistant Bacterial Infection
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title_sort	bacteriophage-delivering hydrogels: current progress in combating antibiotic resistant bacterial infection
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title_auth	Bacteriophage-Delivering Hydrogels: Current Progress in Combating Antibiotic Resistant Bacterial Infection
abstract	Antibiotic resistance remains as an unresolved global challenge in the health care system, posing serious threats to global health. As an alternative to antibiotics, bacteriophage (phage) therapy is rising as a key to combating antibiotic-resistant bacterial infections. In order to deliver a phage to the site of infection, hydrogels have been formulated to incorporate phages, owing to its favorable characteristics in delivering biological molecules. This paper reviews the formulation of phage-delivering hydrogels for orthopedic implant-associated bone infection, catheter-associated urinary tract infection and trauma-associated wound infection, with a focus on the preparation methods, stability, efficacy and safety of hydrogels as phage carriers.
abstractGer	Antibiotic resistance remains as an unresolved global challenge in the health care system, posing serious threats to global health. As an alternative to antibiotics, bacteriophage (phage) therapy is rising as a key to combating antibiotic-resistant bacterial infections. In order to deliver a phage to the site of infection, hydrogels have been formulated to incorporate phages, owing to its favorable characteristics in delivering biological molecules. This paper reviews the formulation of phage-delivering hydrogels for orthopedic implant-associated bone infection, catheter-associated urinary tract infection and trauma-associated wound infection, with a focus on the preparation methods, stability, efficacy and safety of hydrogels as phage carriers.
abstract_unstemmed	Antibiotic resistance remains as an unresolved global challenge in the health care system, posing serious threats to global health. As an alternative to antibiotics, bacteriophage (phage) therapy is rising as a key to combating antibiotic-resistant bacterial infections. In order to deliver a phage to the site of infection, hydrogels have been formulated to incorporate phages, owing to its favorable characteristics in delivering biological molecules. This paper reviews the formulation of phage-delivering hydrogels for orthopedic implant-associated bone infection, catheter-associated urinary tract infection and trauma-associated wound infection, with a focus on the preparation methods, stability, efficacy and safety of hydrogels as phage carriers.
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title_short	Bacteriophage-Delivering Hydrogels: Current Progress in Combating Antibiotic Resistant Bacterial Infection
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