Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens

High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Jianping Wang [verfasserIn] Zengqiao Yang [verfasserIn] Pietro Celi [verfasserIn] Lei Yan [verfasserIn] Xuemei Ding [verfasserIn] Shiping Bai [verfasserIn] Qiufeng Zeng [verfasserIn] Xiangbing Mao [verfasserIn] Bing Feng [verfasserIn] Shengyu Xu [verfasserIn] Keying Zhang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	antioxidant capacity gut microbiota layers molybdenum tea polyphenols

Übergeordnetes Werk:	In: Antioxidants - MDPI AG, 2013, 8(2019), 10, p 503
Übergeordnetes Werk:	volume:8 ; year:2019 ; number:10, p 503

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/antiox8100503

Katalog-ID:	DOAJ073233781

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520			\|a High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge.
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allfields	10.3390/antiox8100503 doi (DE-627)DOAJ073233781 (DE-599)DOAJ9df72c8698524a9892d3af6eef97641e DE-627 ger DE-627 rakwb eng RM1-950 Jianping Wang verfasserin aut Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge. antioxidant capacity gut microbiota layers molybdenum tea polyphenols Therapeutics. Pharmacology Zengqiao Yang verfasserin aut Pietro Celi verfasserin aut Lei Yan verfasserin aut Xuemei Ding verfasserin aut Shiping Bai verfasserin aut Qiufeng Zeng verfasserin aut Xiangbing Mao verfasserin aut Bing Feng verfasserin aut Shengyu Xu verfasserin aut Keying Zhang verfasserin aut In Antioxidants MDPI AG, 2013 8(2019), 10, p 503 (DE-627)737287578 (DE-600)2704216-9 20763921 nnns volume:8 year:2019 number:10, p 503 https://doi.org/10.3390/antiox8100503 kostenfrei https://doaj.org/article/9df72c8698524a9892d3af6eef97641e kostenfrei https://www.mdpi.com/2076-3921/8/10/503 kostenfrei https://doaj.org/toc/2076-3921 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 10, p 503
spelling	10.3390/antiox8100503 doi (DE-627)DOAJ073233781 (DE-599)DOAJ9df72c8698524a9892d3af6eef97641e DE-627 ger DE-627 rakwb eng RM1-950 Jianping Wang verfasserin aut Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge. antioxidant capacity gut microbiota layers molybdenum tea polyphenols Therapeutics. Pharmacology Zengqiao Yang verfasserin aut Pietro Celi verfasserin aut Lei Yan verfasserin aut Xuemei Ding verfasserin aut Shiping Bai verfasserin aut Qiufeng Zeng verfasserin aut Xiangbing Mao verfasserin aut Bing Feng verfasserin aut Shengyu Xu verfasserin aut Keying Zhang verfasserin aut In Antioxidants MDPI AG, 2013 8(2019), 10, p 503 (DE-627)737287578 (DE-600)2704216-9 20763921 nnns volume:8 year:2019 number:10, p 503 https://doi.org/10.3390/antiox8100503 kostenfrei https://doaj.org/article/9df72c8698524a9892d3af6eef97641e kostenfrei https://www.mdpi.com/2076-3921/8/10/503 kostenfrei https://doaj.org/toc/2076-3921 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 10, p 503
allfields_unstemmed	10.3390/antiox8100503 doi (DE-627)DOAJ073233781 (DE-599)DOAJ9df72c8698524a9892d3af6eef97641e DE-627 ger DE-627 rakwb eng RM1-950 Jianping Wang verfasserin aut Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge. antioxidant capacity gut microbiota layers molybdenum tea polyphenols Therapeutics. Pharmacology Zengqiao Yang verfasserin aut Pietro Celi verfasserin aut Lei Yan verfasserin aut Xuemei Ding verfasserin aut Shiping Bai verfasserin aut Qiufeng Zeng verfasserin aut Xiangbing Mao verfasserin aut Bing Feng verfasserin aut Shengyu Xu verfasserin aut Keying Zhang verfasserin aut In Antioxidants MDPI AG, 2013 8(2019), 10, p 503 (DE-627)737287578 (DE-600)2704216-9 20763921 nnns volume:8 year:2019 number:10, p 503 https://doi.org/10.3390/antiox8100503 kostenfrei https://doaj.org/article/9df72c8698524a9892d3af6eef97641e kostenfrei https://www.mdpi.com/2076-3921/8/10/503 kostenfrei https://doaj.org/toc/2076-3921 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 10, p 503
allfieldsGer	10.3390/antiox8100503 doi (DE-627)DOAJ073233781 (DE-599)DOAJ9df72c8698524a9892d3af6eef97641e DE-627 ger DE-627 rakwb eng RM1-950 Jianping Wang verfasserin aut Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge. antioxidant capacity gut microbiota layers molybdenum tea polyphenols Therapeutics. Pharmacology Zengqiao Yang verfasserin aut Pietro Celi verfasserin aut Lei Yan verfasserin aut Xuemei Ding verfasserin aut Shiping Bai verfasserin aut Qiufeng Zeng verfasserin aut Xiangbing Mao verfasserin aut Bing Feng verfasserin aut Shengyu Xu verfasserin aut Keying Zhang verfasserin aut In Antioxidants MDPI AG, 2013 8(2019), 10, p 503 (DE-627)737287578 (DE-600)2704216-9 20763921 nnns volume:8 year:2019 number:10, p 503 https://doi.org/10.3390/antiox8100503 kostenfrei https://doaj.org/article/9df72c8698524a9892d3af6eef97641e kostenfrei https://www.mdpi.com/2076-3921/8/10/503 kostenfrei https://doaj.org/toc/2076-3921 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 10, p 503
allfieldsSound	10.3390/antiox8100503 doi (DE-627)DOAJ073233781 (DE-599)DOAJ9df72c8698524a9892d3af6eef97641e DE-627 ger DE-627 rakwb eng RM1-950 Jianping Wang verfasserin aut Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge. antioxidant capacity gut microbiota layers molybdenum tea polyphenols Therapeutics. Pharmacology Zengqiao Yang verfasserin aut Pietro Celi verfasserin aut Lei Yan verfasserin aut Xuemei Ding verfasserin aut Shiping Bai verfasserin aut Qiufeng Zeng verfasserin aut Xiangbing Mao verfasserin aut Bing Feng verfasserin aut Shengyu Xu verfasserin aut Keying Zhang verfasserin aut In Antioxidants MDPI AG, 2013 8(2019), 10, p 503 (DE-627)737287578 (DE-600)2704216-9 20763921 nnns volume:8 year:2019 number:10, p 503 https://doi.org/10.3390/antiox8100503 kostenfrei https://doaj.org/article/9df72c8698524a9892d3af6eef97641e kostenfrei https://www.mdpi.com/2076-3921/8/10/503 kostenfrei https://doaj.org/toc/2076-3921 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2019 10, p 503
language	English
source	In Antioxidants 8(2019), 10, p 503 volume:8 year:2019 number:10, p 503
sourceStr	In Antioxidants 8(2019), 10, p 503 volume:8 year:2019 number:10, p 503
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	antioxidant capacity gut microbiota layers molybdenum tea polyphenols Therapeutics. Pharmacology
isfreeaccess_bool	true
container_title	Antioxidants
authorswithroles_txt_mv	Jianping Wang @@aut@@ Zengqiao Yang @@aut@@ Pietro Celi @@aut@@ Lei Yan @@aut@@ Xuemei Ding @@aut@@ Shiping Bai @@aut@@ Qiufeng Zeng @@aut@@ Xiangbing Mao @@aut@@ Bing Feng @@aut@@ Shengyu Xu @@aut@@ Keying Zhang @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
hierarchy_top_id	737287578
id	DOAJ073233781
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ073233781</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230309113847.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2019 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/antiox8100503</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ073233781</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ9df72c8698524a9892d3af6eef97641e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RM1-950</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Jianping Wang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< &lt; 0.01). Egg yolk color was decreased by high MO (<i<p</i< &lt; 0.01), while dietary TP had no effect on yolk color (<i<p</i< &gt; 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< &lt; 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< &lt; 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< &lt; 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< &lt; 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). 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callnumber-first	R - Medicine
author	Jianping Wang
spellingShingle	Jianping Wang misc RM1-950 misc antioxidant capacity misc gut microbiota misc layers misc molybdenum misc tea polyphenols misc Therapeutics. Pharmacology Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens
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topic_title	RM1-950 Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens antioxidant capacity gut microbiota layers molybdenum tea polyphenols
topic	misc RM1-950 misc antioxidant capacity misc gut microbiota misc layers misc molybdenum misc tea polyphenols misc Therapeutics. Pharmacology
topic_unstemmed	misc RM1-950 misc antioxidant capacity misc gut microbiota misc layers misc molybdenum misc tea polyphenols misc Therapeutics. Pharmacology
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title	Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens
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title_full	Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens
author_sort	Jianping Wang
journal	Antioxidants
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author_browse	Jianping Wang Zengqiao Yang Pietro Celi Lei Yan Xuemei Ding Shiping Bai Qiufeng Zeng Xiangbing Mao Bing Feng Shengyu Xu Keying Zhang
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title_sort	alteration of the antioxidant capacity and gut microbiota under high levels of molybdenum and green tea polyphenols in laying hens
callnumber	RM1-950
title_auth	Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens
abstract	High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge.
abstractGer	High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge.
abstract_unstemmed	High dietary levels of molybdenum (MO) can negatively affect productive performances and health status of laying hens, while tea polyphenol (TP) can mitigate the negative impact of high MO exposure. However, our understanding of the changes induced by TP on MO challenged layers performances and oxidative status, and on the microbiota, remains limited. The aim of the present study was to better understand host (performances and redox balance) and microbiota responses in MO-challenged layers with dietary TP. In this study, 200 Lohmann laying hens (65-week-old) were randomly allocated in a 2 × 2 factorial design to receive a diet with or without MO (0 or 100 mg/kg), and supplemented with either 0 or 600 mg/kg TP. The results indicate that 100 mg/kg MO decreased egg production (<i<p</i< = 0.03), while dietary TP increased egg production in MO challenged layers (<i<p</i< < 0.01). Egg yolk color was decreased by high MO (<i<p</i< < 0.01), while dietary TP had no effect on yolk color (<i<p</i< > 0.05). Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< < 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< < 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< < 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< < 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). Microbiota analysis revealed differentially enriched microbial compositions in the cecum caused by MO and TP, which might be responsible for the protective effect of dietary TP during a MO challenge.
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title_short	Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens
url	https://doi.org/10.3390/antiox8100503 https://doaj.org/article/9df72c8698524a9892d3af6eef97641e https://www.mdpi.com/2076-3921/8/10/503 https://doaj.org/toc/2076-3921
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Serum alanine transaminase (ALT), aspartate aminotransferase (AST), and malonaldehyde (MDA) concentration were increased by high MO, while total antioxidant capacity (T-AOC), xanthine oxidase (XOD) activity, glutathione s-transferase (GSH-ST), and glutathione concentration in serum were decreased (<i<p</i< &lt; 0.05). Dietary TP was able to reverse the increasing effect of MO on ALT and AST (<i<p</i< &lt; 0.05). High MO resulted in higher MO levels in serum, liver, kidney, and egg, but it decreased Cu and Se content in serum, liver, and egg (<i<p</i< &lt; 0.05). The Fe concentration in liver, kidney, and eggs was significantly lower in MO supplementation groups (<i<p</i< &lt; 0.05). High MO levels in the diet led to lower <i<Firmicutes</i< and higher <i<Proteobacteria</i< abundance, whereas dietary TP alone and/or in high MO treatment increased the <i<Firmicutes</i< abundance and the <i<Firmicutes/Bacteroidetes</i< ratio at phylum level. High MO increased the abundance of <i<Proteobacteria</i< (phylum), <i<Deltaproteobacteria</i< (class), <i<Mytococcales</i< (order), and <i<Nanocystaceae</i< (family), whereas dietary TP promoted the enrichment of <i<Lactobacillus agilis</i< (species). Dietary TP also enhanced the enrichment of <i<Bacilli</i< (class), <i<Lactobacillates</i< (order), <i<Lactobacillus</i< (family), and <i<Lactobacillus gasseri</i< (species). 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Alteration of the Antioxidant Capacity and Gut Microbiota under High Levels of Molybdenum and Green Tea Polyphenols in Laying Hens

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