Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profi...
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Autor*in:	Chunxia Wang [verfasserIn] Robert Batey [verfasserIn] Johji Yamahara [verfasserIn] Yuhao Li [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	Adipose tissue Gene/protein Ginger Liver Skeletal muscle

Übergeordnetes Werk:	In: Journal of Functional Foods - Elsevier, 2021, 36(2017), Seite 43-51
Übergeordnetes Werk:	volume:36 ; year:2017 ; pages:43-51

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.jff.2017.06.040

Katalog-ID:	DOAJ073478601

Internformat


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520			\|a Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits.
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publishDate	2017
allfields	10.1016/j.jff.2017.06.040 doi (DE-627)DOAJ073478601 (DE-599)DOAJ581bfd21d47f4b9a918a98ee33a7bbc5 DE-627 ger DE-627 rakwb eng TX341-641 Chunxia Wang verfasserin aut Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits. Adipose tissue Gene/protein Ginger Liver Skeletal muscle Nutrition. Foods and food supply Robert Batey verfasserin aut Johji Yamahara verfasserin aut Yuhao Li verfasserin aut In Journal of Functional Foods Elsevier, 2021 36(2017), Seite 43-51 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:36 year:2017 pages:43-51 https://doi.org/10.1016/j.jff.2017.06.040 kostenfrei https://doaj.org/article/581bfd21d47f4b9a918a98ee33a7bbc5 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464617303572 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2098 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 36 2017 43-51
spelling	10.1016/j.jff.2017.06.040 doi (DE-627)DOAJ073478601 (DE-599)DOAJ581bfd21d47f4b9a918a98ee33a7bbc5 DE-627 ger DE-627 rakwb eng TX341-641 Chunxia Wang verfasserin aut Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits. Adipose tissue Gene/protein Ginger Liver Skeletal muscle Nutrition. Foods and food supply Robert Batey verfasserin aut Johji Yamahara verfasserin aut Yuhao Li verfasserin aut In Journal of Functional Foods Elsevier, 2021 36(2017), Seite 43-51 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:36 year:2017 pages:43-51 https://doi.org/10.1016/j.jff.2017.06.040 kostenfrei https://doaj.org/article/581bfd21d47f4b9a918a98ee33a7bbc5 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464617303572 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2098 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 36 2017 43-51
allfields_unstemmed	10.1016/j.jff.2017.06.040 doi (DE-627)DOAJ073478601 (DE-599)DOAJ581bfd21d47f4b9a918a98ee33a7bbc5 DE-627 ger DE-627 rakwb eng TX341-641 Chunxia Wang verfasserin aut Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits. Adipose tissue Gene/protein Ginger Liver Skeletal muscle Nutrition. Foods and food supply Robert Batey verfasserin aut Johji Yamahara verfasserin aut Yuhao Li verfasserin aut In Journal of Functional Foods Elsevier, 2021 36(2017), Seite 43-51 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:36 year:2017 pages:43-51 https://doi.org/10.1016/j.jff.2017.06.040 kostenfrei https://doaj.org/article/581bfd21d47f4b9a918a98ee33a7bbc5 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464617303572 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2098 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 36 2017 43-51
allfieldsGer	10.1016/j.jff.2017.06.040 doi (DE-627)DOAJ073478601 (DE-599)DOAJ581bfd21d47f4b9a918a98ee33a7bbc5 DE-627 ger DE-627 rakwb eng TX341-641 Chunxia Wang verfasserin aut Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits. Adipose tissue Gene/protein Ginger Liver Skeletal muscle Nutrition. Foods and food supply Robert Batey verfasserin aut Johji Yamahara verfasserin aut Yuhao Li verfasserin aut In Journal of Functional Foods Elsevier, 2021 36(2017), Seite 43-51 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:36 year:2017 pages:43-51 https://doi.org/10.1016/j.jff.2017.06.040 kostenfrei https://doaj.org/article/581bfd21d47f4b9a918a98ee33a7bbc5 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464617303572 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2098 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 36 2017 43-51
allfieldsSound	10.1016/j.jff.2017.06.040 doi (DE-627)DOAJ073478601 (DE-599)DOAJ581bfd21d47f4b9a918a98ee33a7bbc5 DE-627 ger DE-627 rakwb eng TX341-641 Chunxia Wang verfasserin aut Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits. Adipose tissue Gene/protein Ginger Liver Skeletal muscle Nutrition. Foods and food supply Robert Batey verfasserin aut Johji Yamahara verfasserin aut Yuhao Li verfasserin aut In Journal of Functional Foods Elsevier, 2021 36(2017), Seite 43-51 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:36 year:2017 pages:43-51 https://doi.org/10.1016/j.jff.2017.06.040 kostenfrei https://doaj.org/article/581bfd21d47f4b9a918a98ee33a7bbc5 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464617303572 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2039 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2070 GBV_ILN_2086 GBV_ILN_2088 GBV_ILN_2098 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2116 GBV_ILN_2118 GBV_ILN_2119 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2188 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 36 2017 43-51
language	English
source	In Journal of Functional Foods 36(2017), Seite 43-51 volume:36 year:2017 pages:43-51
sourceStr	In Journal of Functional Foods 36(2017), Seite 43-51 volume:36 year:2017 pages:43-51
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Adipose tissue Gene/protein Ginger Liver Skeletal muscle Nutrition. Foods and food supply
isfreeaccess_bool	true
container_title	Journal of Functional Foods
authorswithroles_txt_mv	Chunxia Wang @@aut@@ Robert Batey @@aut@@ Johji Yamahara @@aut@@ Yuhao Li @@aut@@
publishDateDaySort_date	2017-01-01T00:00:00Z
hierarchy_top_id	587138432
id	DOAJ073478601
language_de	englisch
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callnumber-first	T - Technology
author	Chunxia Wang
spellingShingle	Chunxia Wang misc TX341-641 misc Adipose tissue misc Gene/protein misc Ginger misc Liver misc Skeletal muscle misc Nutrition. Foods and food supply Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease
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topic_title	TX341-641 Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease Adipose tissue Gene/protein Ginger Liver Skeletal muscle
topic	misc TX341-641 misc Adipose tissue misc Gene/protein misc Ginger misc Liver misc Skeletal muscle misc Nutrition. Foods and food supply
topic_unstemmed	misc TX341-641 misc Adipose tissue misc Gene/protein misc Ginger misc Liver misc Skeletal muscle misc Nutrition. Foods and food supply
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title	Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease
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title_full	Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease
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title_sort	multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease
callnumber	TX341-641
title_auth	Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease
abstract	Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits.
abstractGer	Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits.
abstract_unstemmed	Nonalcoholic fatty liver disease (NAFLD) with a high population incidence has a multifactorial basis and is associated with dysfunction of multiple molecules in the liver, adipose tissue and skeletal muscle. To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. More importantly, clinical studies are warranted to assess its therapeutic benefits.
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title_short	Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease
url	https://doi.org/10.1016/j.jff.2017.06.040 https://doaj.org/article/581bfd21d47f4b9a918a98ee33a7bbc5 http://www.sciencedirect.com/science/article/pii/S1756464617303572 https://doaj.org/toc/1756-4646
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up_date	2024-07-03T17:54:21.300Z
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To treat this complex disease, a balanced modulation of multiple targets can provide a profile with superior therapeutic benefits and less side effect, compared to a single selective ligand. Ginger is one of the most commonly used spices and functional foods around the world. An increasing body of evidence has demonstrated that ginger contains many active ingredients (such as gingerols and shoagals) and ameliorates NAFLD-associated disorders by acting on multiple genes/proteins responsible for lipid metabolism, insulin sensitivity and inflammatory responses in the liver, adipose tissue and skeletal muscle. More studies are needed to further investigate how ginger modulates the molecular targets. 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Multiple molecular targets in the liver, adipose tissue and skeletal muscle in ginger-elicited amelioration of nonalcoholic fatty liver disease

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