Research Progress of Immunotherapy Biomarkers for Non-small Cell Lung Cancer
Lung cancer is one of the most prevalent malignancies with the highest morbidity and mortality rates worldwide. In recent years, with the development of immune-oncology research and several therapeutic antibodies have reach the clinic, many breakthroughs have been made in immunotherapy. The advent o...
Ausführliche Beschreibung
Autor*in: |
Chang JIANG [verfasserIn] Ling YI [verfasserIn] Xiang GAO [verfasserIn] Hongtao ZHANG [verfasserIn] Shucai ZHANG [verfasserIn] |
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E-Artikel |
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Sprache: |
Chinesisch |
Erschienen: |
2022 |
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Schlagwörter: |
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Übergeordnetes Werk: |
In: Chinese Journal of Lung Cancer - Chinese Anti-Cancer Association; Chinese Antituberculosis Association, 2008, 25(2022), 1, Seite 46-53 |
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Übergeordnetes Werk: |
volume:25 ; year:2022 ; number:1 ; pages:46-53 |
Links: |
Link aufrufen |
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DOI / URN: |
10.3779/j.issn.1009-3419.2021.102.55 |
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Katalog-ID: |
DOAJ073516902 |
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10.3779/j.issn.1009-3419.2021.102.55 doi (DE-627)DOAJ073516902 (DE-599)DOAJ78ea8da0f1b947d2bfeea8b357218deb DE-627 ger DE-627 rakwb chi RC254-282 Chang JIANG verfasserin aut Research Progress of Immunotherapy Biomarkers for Non-small Cell Lung Cancer 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Lung cancer is one of the most prevalent malignancies with the highest morbidity and mortality rates worldwide. In recent years, with the development of immune-oncology research and several therapeutic antibodies have reach the clinic, many breakthroughs have been made in immunotherapy. The advent of immunotherapy has revolutionized the treatment of NSCLC, but the response and durable clinical benefit are only observed in a small subset of patients. Therefore, strategies to screen the potential beneficial population and improve the efficacy of immunotherapy remain an essential topic. In the current article, the author review the biomarkers that have potential to better predict responders to immunotherapy and to provide ideas for the clinical application of immunotherapy. nsclc immunotherapy biomarker pd-l1 tmb Neoplasms. Tumors. Oncology. Including cancer and carcinogens Ling YI verfasserin aut Xiang GAO verfasserin aut Hongtao ZHANG verfasserin aut Shucai ZHANG verfasserin aut In Chinese Journal of Lung Cancer Chinese Anti-Cancer Association; Chinese Antituberculosis Association, 2008 25(2022), 1, Seite 46-53 (DE-627)572421125 (DE-600)2438672-8 19996187 nnns volume:25 year:2022 number:1 pages:46-53 https://doi.org/10.3779/j.issn.1009-3419.2021.102.55 kostenfrei https://doaj.org/article/78ea8da0f1b947d2bfeea8b357218deb kostenfrei http://dx.doi.org/10.3779/j.issn.1009-3419.2021.102.55 kostenfrei https://doaj.org/toc/1009-3419 Journal toc kostenfrei https://doaj.org/toc/1999-6187 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2106 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2022 1 46-53 |
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10.3779/j.issn.1009-3419.2021.102.55 doi (DE-627)DOAJ073516902 (DE-599)DOAJ78ea8da0f1b947d2bfeea8b357218deb DE-627 ger DE-627 rakwb chi RC254-282 Chang JIANG verfasserin aut Research Progress of Immunotherapy Biomarkers for Non-small Cell Lung Cancer 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Lung cancer is one of the most prevalent malignancies with the highest morbidity and mortality rates worldwide. In recent years, with the development of immune-oncology research and several therapeutic antibodies have reach the clinic, many breakthroughs have been made in immunotherapy. The advent of immunotherapy has revolutionized the treatment of NSCLC, but the response and durable clinical benefit are only observed in a small subset of patients. Therefore, strategies to screen the potential beneficial population and improve the efficacy of immunotherapy remain an essential topic. In the current article, the author review the biomarkers that have potential to better predict responders to immunotherapy and to provide ideas for the clinical application of immunotherapy. nsclc immunotherapy biomarker pd-l1 tmb Neoplasms. Tumors. Oncology. Including cancer and carcinogens Ling YI verfasserin aut Xiang GAO verfasserin aut Hongtao ZHANG verfasserin aut Shucai ZHANG verfasserin aut In Chinese Journal of Lung Cancer Chinese Anti-Cancer Association; Chinese Antituberculosis Association, 2008 25(2022), 1, Seite 46-53 (DE-627)572421125 (DE-600)2438672-8 19996187 nnns volume:25 year:2022 number:1 pages:46-53 https://doi.org/10.3779/j.issn.1009-3419.2021.102.55 kostenfrei https://doaj.org/article/78ea8da0f1b947d2bfeea8b357218deb kostenfrei http://dx.doi.org/10.3779/j.issn.1009-3419.2021.102.55 kostenfrei https://doaj.org/toc/1009-3419 Journal toc kostenfrei https://doaj.org/toc/1999-6187 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2106 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2022 1 46-53 |
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Lung cancer is one of the most prevalent malignancies with the highest morbidity and mortality rates worldwide. In recent years, with the development of immune-oncology research and several therapeutic antibodies have reach the clinic, many breakthroughs have been made in immunotherapy. The advent of immunotherapy has revolutionized the treatment of NSCLC, but the response and durable clinical benefit are only observed in a small subset of patients. Therefore, strategies to screen the potential beneficial population and improve the efficacy of immunotherapy remain an essential topic. In the current article, the author review the biomarkers that have potential to better predict responders to immunotherapy and to provide ideas for the clinical application of immunotherapy. |
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Lung cancer is one of the most prevalent malignancies with the highest morbidity and mortality rates worldwide. In recent years, with the development of immune-oncology research and several therapeutic antibodies have reach the clinic, many breakthroughs have been made in immunotherapy. The advent of immunotherapy has revolutionized the treatment of NSCLC, but the response and durable clinical benefit are only observed in a small subset of patients. Therefore, strategies to screen the potential beneficial population and improve the efficacy of immunotherapy remain an essential topic. In the current article, the author review the biomarkers that have potential to better predict responders to immunotherapy and to provide ideas for the clinical application of immunotherapy. |
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Lung cancer is one of the most prevalent malignancies with the highest morbidity and mortality rates worldwide. In recent years, with the development of immune-oncology research and several therapeutic antibodies have reach the clinic, many breakthroughs have been made in immunotherapy. The advent of immunotherapy has revolutionized the treatment of NSCLC, but the response and durable clinical benefit are only observed in a small subset of patients. Therefore, strategies to screen the potential beneficial population and improve the efficacy of immunotherapy remain an essential topic. In the current article, the author review the biomarkers that have potential to better predict responders to immunotherapy and to provide ideas for the clinical application of immunotherapy. |
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