"Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency "

Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old...
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Autor*in:	Nasser Ebrahimi Daryani [verfasserIn] Asghar Aghamohammadi [verfasserIn] Mohammad-Reza Mousavi Mirkala [verfasserIn] Mohammad Bashashati [verfasserIn] Nima Rezaei [verfasserIn] Babak Haghpanah [verfasserIn] Ali-Asad Hashtroudi [verfasserIn] Alireza Sayyah [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2004

Schlagwörter:	Diarrhoea Gastrointestinal Diseases

Übergeordnetes Werk:	In: Iranian Journal of Allergy, Asthma and Immunology - Tehran University of Medical Sciences, 2020, 3(2004), 3
Übergeordnetes Werk:	volume:3 ; year:2004 ; number:3

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ074449214

Internformat


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520			\|a Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients.
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allfields	(DE-627)DOAJ074449214 (DE-599)DOAJ8f436ddfe0b14da2b7795ba65b23a2bd DE-627 ger DE-627 rakwb eng Nasser Ebrahimi Daryani verfasserin aut "Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency " 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients. Diarrhoea Gastrointestinal Diseases Medicine R Asghar Aghamohammadi verfasserin aut Mohammad-Reza Mousavi Mirkala verfasserin aut Mohammad Bashashati verfasserin aut Nima Rezaei verfasserin aut Babak Haghpanah verfasserin aut Ali-Asad Hashtroudi verfasserin aut Alireza Sayyah verfasserin aut In Iranian Journal of Allergy, Asthma and Immunology Tehran University of Medical Sciences, 2020 3(2004), 3 (DE-627)545784166 (DE-600)2388260-8 17355249 nnns volume:3 year:2004 number:3 https://doaj.org/article/8f436ddfe0b14da2b7795ba65b23a2bd kostenfrei https://ijaai.tums.ac.ir/index.php/ijaai/article/view/83 kostenfrei https://doaj.org/toc/1735-1502 Journal toc kostenfrei https://doaj.org/toc/1735-5249 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2004 3
spelling	(DE-627)DOAJ074449214 (DE-599)DOAJ8f436ddfe0b14da2b7795ba65b23a2bd DE-627 ger DE-627 rakwb eng Nasser Ebrahimi Daryani verfasserin aut "Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency " 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients. Diarrhoea Gastrointestinal Diseases Medicine R Asghar Aghamohammadi verfasserin aut Mohammad-Reza Mousavi Mirkala verfasserin aut Mohammad Bashashati verfasserin aut Nima Rezaei verfasserin aut Babak Haghpanah verfasserin aut Ali-Asad Hashtroudi verfasserin aut Alireza Sayyah verfasserin aut In Iranian Journal of Allergy, Asthma and Immunology Tehran University of Medical Sciences, 2020 3(2004), 3 (DE-627)545784166 (DE-600)2388260-8 17355249 nnns volume:3 year:2004 number:3 https://doaj.org/article/8f436ddfe0b14da2b7795ba65b23a2bd kostenfrei https://ijaai.tums.ac.ir/index.php/ijaai/article/view/83 kostenfrei https://doaj.org/toc/1735-1502 Journal toc kostenfrei https://doaj.org/toc/1735-5249 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2004 3
allfields_unstemmed	(DE-627)DOAJ074449214 (DE-599)DOAJ8f436ddfe0b14da2b7795ba65b23a2bd DE-627 ger DE-627 rakwb eng Nasser Ebrahimi Daryani verfasserin aut "Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency " 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients. Diarrhoea Gastrointestinal Diseases Medicine R Asghar Aghamohammadi verfasserin aut Mohammad-Reza Mousavi Mirkala verfasserin aut Mohammad Bashashati verfasserin aut Nima Rezaei verfasserin aut Babak Haghpanah verfasserin aut Ali-Asad Hashtroudi verfasserin aut Alireza Sayyah verfasserin aut In Iranian Journal of Allergy, Asthma and Immunology Tehran University of Medical Sciences, 2020 3(2004), 3 (DE-627)545784166 (DE-600)2388260-8 17355249 nnns volume:3 year:2004 number:3 https://doaj.org/article/8f436ddfe0b14da2b7795ba65b23a2bd kostenfrei https://ijaai.tums.ac.ir/index.php/ijaai/article/view/83 kostenfrei https://doaj.org/toc/1735-1502 Journal toc kostenfrei https://doaj.org/toc/1735-5249 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2004 3
allfieldsGer	(DE-627)DOAJ074449214 (DE-599)DOAJ8f436ddfe0b14da2b7795ba65b23a2bd DE-627 ger DE-627 rakwb eng Nasser Ebrahimi Daryani verfasserin aut "Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency " 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients. Diarrhoea Gastrointestinal Diseases Medicine R Asghar Aghamohammadi verfasserin aut Mohammad-Reza Mousavi Mirkala verfasserin aut Mohammad Bashashati verfasserin aut Nima Rezaei verfasserin aut Babak Haghpanah verfasserin aut Ali-Asad Hashtroudi verfasserin aut Alireza Sayyah verfasserin aut In Iranian Journal of Allergy, Asthma and Immunology Tehran University of Medical Sciences, 2020 3(2004), 3 (DE-627)545784166 (DE-600)2388260-8 17355249 nnns volume:3 year:2004 number:3 https://doaj.org/article/8f436ddfe0b14da2b7795ba65b23a2bd kostenfrei https://ijaai.tums.ac.ir/index.php/ijaai/article/view/83 kostenfrei https://doaj.org/toc/1735-1502 Journal toc kostenfrei https://doaj.org/toc/1735-5249 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2004 3
allfieldsSound	(DE-627)DOAJ074449214 (DE-599)DOAJ8f436ddfe0b14da2b7795ba65b23a2bd DE-627 ger DE-627 rakwb eng Nasser Ebrahimi Daryani verfasserin aut "Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency " 2004 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients. Diarrhoea Gastrointestinal Diseases Medicine R Asghar Aghamohammadi verfasserin aut Mohammad-Reza Mousavi Mirkala verfasserin aut Mohammad Bashashati verfasserin aut Nima Rezaei verfasserin aut Babak Haghpanah verfasserin aut Ali-Asad Hashtroudi verfasserin aut Alireza Sayyah verfasserin aut In Iranian Journal of Allergy, Asthma and Immunology Tehran University of Medical Sciences, 2020 3(2004), 3 (DE-627)545784166 (DE-600)2388260-8 17355249 nnns volume:3 year:2004 number:3 https://doaj.org/article/8f436ddfe0b14da2b7795ba65b23a2bd kostenfrei https://ijaai.tums.ac.ir/index.php/ijaai/article/view/83 kostenfrei https://doaj.org/toc/1735-1502 Journal toc kostenfrei https://doaj.org/toc/1735-5249 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2004 3
language	English
source	In Iranian Journal of Allergy, Asthma and Immunology 3(2004), 3 volume:3 year:2004 number:3
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topic_facet	Diarrhoea Gastrointestinal Diseases Medicine R
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container_title	Iranian Journal of Allergy, Asthma and Immunology
authorswithroles_txt_mv	Nasser Ebrahimi Daryani @@aut@@ Asghar Aghamohammadi @@aut@@ Mohammad-Reza Mousavi Mirkala @@aut@@ Mohammad Bashashati @@aut@@ Nima Rezaei @@aut@@ Babak Haghpanah @@aut@@ Ali-Asad Hashtroudi @@aut@@ Alireza Sayyah @@aut@@
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We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. 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spellingShingle	Nasser Ebrahimi Daryani misc Diarrhoea misc Gastrointestinal Diseases misc Medicine misc R "Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency "
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title	"Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency "
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title_full	"Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency "
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author_browse	Nasser Ebrahimi Daryani Asghar Aghamohammadi Mohammad-Reza Mousavi Mirkala Mohammad Bashashati Nima Rezaei Babak Haghpanah Ali-Asad Hashtroudi Alireza Sayyah
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title_sort	"gastrointestinal complications in two patients with common variable immunodeficiency "
title_auth	"Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency "
abstract	Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients.
abstractGer	Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients.
abstract_unstemmed	Common variable immunodeficiency (CVID) is a primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. We present here 2 cases of CVID with gastrointestinal complications. Case 1 is a 25-year-old man with a history of chronic diarrhoea from childhood. Ultrasonography revealed ascites, with liver size smaller than normal. Liver biopsy showed non-specific hepatitis. Lymphoid proliferation and Histiocytosis were reported in his ascites cytology. Moreover friability in colonoscopy due to moderate active chronic colitis was detected. Case 2 is a 26-year-old man with chronic diarrhoea since 8 years. Abdominal sonography revealed increased liver echogenicity, increased liver size, and some enlarged lymph nodes beside pancreas. Colonoscopy revealed friability and decreased vascularity while biopsy showed moderate active chronic colitis. Lymph node biopsy showed unusual immunologic reaction. Moreover, small bowel transition test showed nodularity. CVID should be considered in any patient with gastrointestinal manifestations especially chronic diarrhoea in association with recurrent bacterial infections in other organs. Diagnostic delay results in more morbidity and complications in untreated patients.
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title_short	"Gastrointestinal Complications in Two Patients with Common Variable Immunodeficiency "
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