<i<In Vivo</i< Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection
Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledg...
Ausführliche Beschreibung
Autor*in: |
Helena Strand Clemmensen [verfasserIn] Jean-Yves Dube [verfasserIn] Fiona McIntosh [verfasserIn] Ida Rosenkrands [verfasserIn] Gregers Jungersen [verfasserIn] Claus Aagaard [verfasserIn] Peter Andersen [verfasserIn] Marcel A. Behr [verfasserIn] Rasmus Mortensen [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Übergeordnetes Werk: |
In: mBio - American Society for Microbiology, 2010, 12(2021), 2 |
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Übergeordnetes Werk: |
volume:12 ; year:2021 ; number:2 |
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DOI / URN: |
10.1128/mBio.00226-21 |
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DOAJ074580132 |
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10.1128/mBio.00226-21 doi (DE-627)DOAJ074580132 (DE-599)DOAJ2ebf09603932441099af75020674a1ba DE-627 ger DE-627 rakwb eng QR1-502 Helena Strand Clemmensen verfasserin aut <i<In Vivo</i< Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. Microbiology Jean-Yves Dube verfasserin aut Fiona McIntosh verfasserin aut Ida Rosenkrands verfasserin aut Gregers Jungersen verfasserin aut Claus Aagaard verfasserin aut Peter Andersen verfasserin aut Marcel A. Behr verfasserin aut Rasmus Mortensen verfasserin aut In mBio American Society for Microbiology, 2010 12(2021), 2 (DE-627)627613543 (DE-600)2557172-2 21507511 nnns volume:12 year:2021 number:2 https://doi.org/10.1128/mBio.00226-21 kostenfrei https://doaj.org/article/2ebf09603932441099af75020674a1ba kostenfrei https://journals.asm.org/doi/10.1128/mBio.00226-21 kostenfrei https://doaj.org/toc/2150-7511 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 2 |
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10.1128/mBio.00226-21 doi (DE-627)DOAJ074580132 (DE-599)DOAJ2ebf09603932441099af75020674a1ba DE-627 ger DE-627 rakwb eng QR1-502 Helena Strand Clemmensen verfasserin aut <i<In Vivo</i< Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. Microbiology Jean-Yves Dube verfasserin aut Fiona McIntosh verfasserin aut Ida Rosenkrands verfasserin aut Gregers Jungersen verfasserin aut Claus Aagaard verfasserin aut Peter Andersen verfasserin aut Marcel A. Behr verfasserin aut Rasmus Mortensen verfasserin aut In mBio American Society for Microbiology, 2010 12(2021), 2 (DE-627)627613543 (DE-600)2557172-2 21507511 nnns volume:12 year:2021 number:2 https://doi.org/10.1128/mBio.00226-21 kostenfrei https://doaj.org/article/2ebf09603932441099af75020674a1ba kostenfrei https://journals.asm.org/doi/10.1128/mBio.00226-21 kostenfrei https://doaj.org/toc/2150-7511 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 2 |
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10.1128/mBio.00226-21 doi (DE-627)DOAJ074580132 (DE-599)DOAJ2ebf09603932441099af75020674a1ba DE-627 ger DE-627 rakwb eng QR1-502 Helena Strand Clemmensen verfasserin aut <i<In Vivo</i< Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. Microbiology Jean-Yves Dube verfasserin aut Fiona McIntosh verfasserin aut Ida Rosenkrands verfasserin aut Gregers Jungersen verfasserin aut Claus Aagaard verfasserin aut Peter Andersen verfasserin aut Marcel A. Behr verfasserin aut Rasmus Mortensen verfasserin aut In mBio American Society for Microbiology, 2010 12(2021), 2 (DE-627)627613543 (DE-600)2557172-2 21507511 nnns volume:12 year:2021 number:2 https://doi.org/10.1128/mBio.00226-21 kostenfrei https://doaj.org/article/2ebf09603932441099af75020674a1ba kostenfrei https://journals.asm.org/doi/10.1128/mBio.00226-21 kostenfrei https://doaj.org/toc/2150-7511 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 2 |
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10.1128/mBio.00226-21 doi (DE-627)DOAJ074580132 (DE-599)DOAJ2ebf09603932441099af75020674a1ba DE-627 ger DE-627 rakwb eng QR1-502 Helena Strand Clemmensen verfasserin aut <i<In Vivo</i< Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. Microbiology Jean-Yves Dube verfasserin aut Fiona McIntosh verfasserin aut Ida Rosenkrands verfasserin aut Gregers Jungersen verfasserin aut Claus Aagaard verfasserin aut Peter Andersen verfasserin aut Marcel A. Behr verfasserin aut Rasmus Mortensen verfasserin aut In mBio American Society for Microbiology, 2010 12(2021), 2 (DE-627)627613543 (DE-600)2557172-2 21507511 nnns volume:12 year:2021 number:2 https://doi.org/10.1128/mBio.00226-21 kostenfrei https://doaj.org/article/2ebf09603932441099af75020674a1ba kostenfrei https://journals.asm.org/doi/10.1128/mBio.00226-21 kostenfrei https://doaj.org/toc/2150-7511 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 2 |
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10.1128/mBio.00226-21 doi (DE-627)DOAJ074580132 (DE-599)DOAJ2ebf09603932441099af75020674a1ba DE-627 ger DE-627 rakwb eng QR1-502 Helena Strand Clemmensen verfasserin aut <i<In Vivo</i< Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. Microbiology Jean-Yves Dube verfasserin aut Fiona McIntosh verfasserin aut Ida Rosenkrands verfasserin aut Gregers Jungersen verfasserin aut Claus Aagaard verfasserin aut Peter Andersen verfasserin aut Marcel A. Behr verfasserin aut Rasmus Mortensen verfasserin aut In mBio American Society for Microbiology, 2010 12(2021), 2 (DE-627)627613543 (DE-600)2557172-2 21507511 nnns volume:12 year:2021 number:2 https://doi.org/10.1128/mBio.00226-21 kostenfrei https://doaj.org/article/2ebf09603932441099af75020674a1ba kostenfrei https://journals.asm.org/doi/10.1128/mBio.00226-21 kostenfrei https://doaj.org/toc/2150-7511 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 2 |
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<i<In Vivo</i< Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection |
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Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. |
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Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. |
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Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development. |
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|
score |
7.399617 |