Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<)

Congenital hearing loss is recognized in humans and other terrestrial species. However, there is a lack of information on its prevalence or pathophysiology in pinnipeds. It is important to have baseline knowledge on marine mammal malformations in the inner ear, to differentiate between congenital an...
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Autor*in:	Maria Morell [verfasserIn] Laura Rojas [verfasserIn] Martin Haulena [verfasserIn] Björn Busse [verfasserIn] Ursula Siebert [verfasserIn] Robert E. Shadwick [verfasserIn] Stephen A. Raverty [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	congenital hearing loss organ of Corti marine mammals pinnipeds scanning electron microscopy hair cell loss

Übergeordnetes Werk:	In: Animals - MDPI AG, 2011, 12(2022), 2, p 180
Übergeordnetes Werk:	volume:12 ; year:2022 ; number:2, p 180

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/ani12020180

Katalog-ID:	DOAJ074694634

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callnumber-first	S - Agriculture
author	Maria Morell
spellingShingle	Maria Morell misc SF600-1100 misc QL1-991 misc congenital hearing loss misc organ of Corti misc marine mammals misc pinnipeds misc scanning electron microscopy misc hair cell loss misc Veterinary medicine misc Zoology Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<)
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topic_title	SF600-1100 QL1-991 Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<) congenital hearing loss organ of Corti marine mammals pinnipeds scanning electron microscopy hair cell loss
topic	misc SF600-1100 misc QL1-991 misc congenital hearing loss misc organ of Corti misc marine mammals misc pinnipeds misc scanning electron microscopy misc hair cell loss misc Veterinary medicine misc Zoology
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title	Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<)
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title_full	Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<)
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title_sort	selective inner hair cell loss in a neonate harbor seal (<i<phoca vitulina</i<)
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title_auth	Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<)
abstract	Congenital hearing loss is recognized in humans and other terrestrial species. However, there is a lack of information on its prevalence or pathophysiology in pinnipeds. It is important to have baseline knowledge on marine mammal malformations in the inner ear, to differentiate between congenital and acquired abnormalities, which may be caused by infectious pathogens, age, or anthropogenic interactions, such as noise exposure. Ultrastructural evaluation of the cochlea of a neonate harbor seal (<i<Phoca vitulina</i<) by scanning electron microscopy revealed bilateral loss of inner hair cells with intact outer hair cells. The selective inner hair cell loss was more severe in the basal turn, where high-frequency sounds are encoded. The loss of inner hair cells started around 40% away from the apex or tip of the spiral, reaching a maximum loss of 84.6% of hair cells at 80–85% of the length from the apex. Potential etiologies and consequences are discussed. This is believed to be the first case report of selective inner hair cell loss in a marine mammal neonate, likely congenital.
abstractGer	Congenital hearing loss is recognized in humans and other terrestrial species. However, there is a lack of information on its prevalence or pathophysiology in pinnipeds. It is important to have baseline knowledge on marine mammal malformations in the inner ear, to differentiate between congenital and acquired abnormalities, which may be caused by infectious pathogens, age, or anthropogenic interactions, such as noise exposure. Ultrastructural evaluation of the cochlea of a neonate harbor seal (<i<Phoca vitulina</i<) by scanning electron microscopy revealed bilateral loss of inner hair cells with intact outer hair cells. The selective inner hair cell loss was more severe in the basal turn, where high-frequency sounds are encoded. The loss of inner hair cells started around 40% away from the apex or tip of the spiral, reaching a maximum loss of 84.6% of hair cells at 80–85% of the length from the apex. Potential etiologies and consequences are discussed. This is believed to be the first case report of selective inner hair cell loss in a marine mammal neonate, likely congenital.
abstract_unstemmed	Congenital hearing loss is recognized in humans and other terrestrial species. However, there is a lack of information on its prevalence or pathophysiology in pinnipeds. It is important to have baseline knowledge on marine mammal malformations in the inner ear, to differentiate between congenital and acquired abnormalities, which may be caused by infectious pathogens, age, or anthropogenic interactions, such as noise exposure. Ultrastructural evaluation of the cochlea of a neonate harbor seal (<i<Phoca vitulina</i<) by scanning electron microscopy revealed bilateral loss of inner hair cells with intact outer hair cells. The selective inner hair cell loss was more severe in the basal turn, where high-frequency sounds are encoded. The loss of inner hair cells started around 40% away from the apex or tip of the spiral, reaching a maximum loss of 84.6% of hair cells at 80–85% of the length from the apex. Potential etiologies and consequences are discussed. This is believed to be the first case report of selective inner hair cell loss in a marine mammal neonate, likely congenital.
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title_short	Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<)
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Selective Inner Hair Cell Loss in a Neonate Harbor Seal (<i<Phoca vitulina</i<)

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