Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years

Hofvander and colleagues compare the patterns of clonal evolution in different pathogenetic subgroups of sarcoma. They show that sarcomas driven by gene fusion or amplification display few additional changes over time, whereas sarcomas with complex karyotypes show a gradual increase of nucleotide- a...
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Autor*in:	Jakob Hofvander [verfasserIn] Björn Viklund [verfasserIn] Anders Isaksson [verfasserIn] Otte Brosjö [verfasserIn] Fredrik Vult von Steyern [verfasserIn] Pehr Rissler [verfasserIn] Nils Mandahl [verfasserIn] Fredrik Mertens [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 9(2018), 1, Seite 8
Übergeordnetes Werk:	volume:9 ; year:2018 ; number:1 ; pages:8

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-018-06098-0

Katalog-ID:	DOAJ074746154

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spelling	10.1038/s41467-018-06098-0 doi (DE-627)DOAJ074746154 (DE-599)DOAJ05f473e7440244ce962db1231be2efa6 DE-627 ger DE-627 rakwb eng Jakob Hofvander verfasserin aut Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hofvander and colleagues compare the patterns of clonal evolution in different pathogenetic subgroups of sarcoma. They show that sarcomas driven by gene fusion or amplification display few additional changes over time, whereas sarcomas with complex karyotypes show a gradual increase of nucleotide- and chromosome-level mutations. Science Q Björn Viklund verfasserin aut Anders Isaksson verfasserin aut Otte Brosjö verfasserin aut Fredrik Vult von Steyern verfasserin aut Pehr Rissler verfasserin aut Nils Mandahl verfasserin aut Fredrik Mertens verfasserin aut In Nature Communications Nature Portfolio, 2016 9(2018), 1, Seite 8 (DE-627)626457688 (DE-600)2553671-0 20411723 nnns volume:9 year:2018 number:1 pages:8 https://doi.org/10.1038/s41467-018-06098-0 kostenfrei https://doaj.org/article/05f473e7440244ce962db1231be2efa6 kostenfrei https://doi.org/10.1038/s41467-018-06098-0 kostenfrei https://doaj.org/toc/2041-1723 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_211 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2018 1 8
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author	Jakob Hofvander
spellingShingle	Jakob Hofvander misc Science misc Q Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
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topic_title	Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
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title	Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
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title_full	Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
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author_browse	Jakob Hofvander Björn Viklund Anders Isaksson Otte Brosjö Fredrik Vult von Steyern Pehr Rissler Nils Mandahl Fredrik Mertens
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title_sort	different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
title_auth	Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
abstract	Hofvander and colleagues compare the patterns of clonal evolution in different pathogenetic subgroups of sarcoma. They show that sarcomas driven by gene fusion or amplification display few additional changes over time, whereas sarcomas with complex karyotypes show a gradual increase of nucleotide- and chromosome-level mutations.
abstractGer	Hofvander and colleagues compare the patterns of clonal evolution in different pathogenetic subgroups of sarcoma. They show that sarcomas driven by gene fusion or amplification display few additional changes over time, whereas sarcomas with complex karyotypes show a gradual increase of nucleotide- and chromosome-level mutations.
abstract_unstemmed	Hofvander and colleagues compare the patterns of clonal evolution in different pathogenetic subgroups of sarcoma. They show that sarcomas driven by gene fusion or amplification display few additional changes over time, whereas sarcomas with complex karyotypes show a gradual increase of nucleotide- and chromosome-level mutations.
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title_short	Different patterns of clonal evolution among different sarcoma subtypes followed for up to 25 years
url	https://doi.org/10.1038/s41467-018-06098-0 https://doaj.org/article/05f473e7440244ce962db1231be2efa6 https://doaj.org/toc/2041-1723
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