Anisotropic ESCRT-III architecture governs helical membrane tube formation
ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here, the authors use cryo-ET, cryo-EM and mathematical modeling to reveal how the shape of the helical membrane tube arises from the assembly of two distinct bundles of helical filaments.
Autor*in: |
Joachim Moser von Filseck [verfasserIn] Luca Barberi [verfasserIn] Nathaniel Talledge [verfasserIn] Isabel E. Johnson [verfasserIn] Adam Frost [verfasserIn] Martin Lenz [verfasserIn] Aurélien Roux [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Übergeordnetes Werk: |
In: Nature Communications - Nature Portfolio, 2016, 11(2020), 1, Seite 9 |
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Übergeordnetes Werk: |
volume:11 ; year:2020 ; number:1 ; pages:9 |
Links: |
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DOI / URN: |
10.1038/s41467-020-15327-4 |
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Katalog-ID: |
DOAJ075303396 |
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ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here, the authors use cryo-ET, cryo-EM and mathematical modeling to reveal how the shape of the helical membrane tube arises from the assembly of two distinct bundles of helical filaments. |
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ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here, the authors use cryo-ET, cryo-EM and mathematical modeling to reveal how the shape of the helical membrane tube arises from the assembly of two distinct bundles of helical filaments. |
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