Endoderm Jagged induces liver and pancreas duct lineage in zebrafish

The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebrafish.

Gespeichert in:

Autor*in:	Danhua Zhang [verfasserIn] Keith P. Gates [verfasserIn] Lindsey Barske [verfasserIn] Guangliang Wang [verfasserIn] Joseph J. Lancman [verfasserIn] Xin-Xin I. Zeng [verfasserIn] Megan Groff [verfasserIn] Kasper Wang [verfasserIn] Michael J. Parsons [verfasserIn] J. Gage Crump [verfasserIn] P. Duc Si Dong [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 8(2017), 1, Seite 11
Übergeordnetes Werk:	volume:8 ; year:2017 ; number:1 ; pages:11

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-017-00666-6

Katalog-ID:	DOAJ075415054

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author	Danhua Zhang
spellingShingle	Danhua Zhang misc Science misc Q Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
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topic_title	Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
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title	Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
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title_full	Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
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author_browse	Danhua Zhang Keith P. Gates Lindsey Barske Guangliang Wang Joseph J. Lancman Xin-Xin I. Zeng Megan Groff Kasper Wang Michael J. Parsons J. Gage Crump P. Duc Si Dong
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title_sort	endoderm jagged induces liver and pancreas duct lineage in zebrafish
title_auth	Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
abstract	The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebrafish.
abstractGer	The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebrafish.
abstract_unstemmed	The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebrafish.
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title_short	Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
url	https://doi.org/10.1038/s41467-017-00666-6 https://doaj.org/article/9a869d75f80549c8a2ff75e1bc7269a8 https://doaj.org/toc/2041-1723
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up_date	2024-07-03T14:47:01.350Z
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