Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol

<p<Abstract</p< <p<Background</p< <p<Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without hav...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Bonani Marco G [verfasserIn] Bischofberger Stephan A [verfasserIn] Bischof Dominique B [verfasserIn] Bachmann Lucas M [verfasserIn] Osann Franziska M [verfasserIn] Steurer Johann [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2002

Übergeordnetes Werk:	In: BMC Surgery - BMC, 2003, 2(2002), 1, p 2
Übergeordnetes Werk:	volume:2 ; year:2002 ; number:1, p 2

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/1471-2482-2-2

Katalog-ID:	DOAJ076915867

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spelling	10.1186/1471-2482-2-2 doi (DE-627)DOAJ076915867 (DE-599)DOAJb751a7de7cb54491a56e91fcb3af6aef DE-627 ger DE-627 rakwb eng RD1-811 Bonani Marco G verfasserin aut Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk and entail a serious waste of resources. Several highly accurate tests have been introduced to diagnose acute appendicitis. The false positive rate however, has not changed over the last twenty years. Given the variation that exists in both practice and research, the uncertainty regarding the quality of the underlying evidence, there is a clear need for comprehensive, systematic and quantitative overviews of the diagnostic value of the various tests purported to be predictive of acute appendicitis.</p< <p<Methods</p< <p<Literature will be identified searching general bibliographic databases (MEDLINE and EMBASE), specialist computer databases (DARE, Cochrane Database of Systematic Reviews, conference proceedings, MEDION, SCISEARCH, BIOSIS) without language restrictions. We will contact experts and the manufacturers of tests. Hand-searching will complete our searches. Identified articles will be selected according to populations, tests, outcomes and study design. Papers meeting the selection criteria will be appraised to rate their methodological quality. Analysis will include exploration of heterogeneity in results. We will conduct meta-analyses to generate summary estimates of test accuracy measures and summary ROC curves where appropriate. If meta-analysis is considered to be inappropriate, we will describe the identified evidence in the context of appraised quality.</p< <p<Discussion</p< <p<These reviews should lead to formulation of recommendations for current practice and future research.</p< Surgery Bischofberger Stephan A verfasserin aut Bischof Dominique B verfasserin aut Bachmann Lucas M verfasserin aut Osann Franziska M verfasserin aut Steurer Johann verfasserin aut In BMC Surgery BMC, 2003 2(2002), 1, p 2 (DE-627)331018837 (DE-600)2050442-1 14712482 nnns volume:2 year:2002 number:1, p 2 https://doi.org/10.1186/1471-2482-2-2 kostenfrei https://doaj.org/article/b751a7de7cb54491a56e91fcb3af6aef kostenfrei http://www.biomedcentral.com/1471-2482/2/2 kostenfrei https://doaj.org/toc/1471-2482 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2002 1, p 2
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allfieldsGer	10.1186/1471-2482-2-2 doi (DE-627)DOAJ076915867 (DE-599)DOAJb751a7de7cb54491a56e91fcb3af6aef DE-627 ger DE-627 rakwb eng RD1-811 Bonani Marco G verfasserin aut Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk and entail a serious waste of resources. Several highly accurate tests have been introduced to diagnose acute appendicitis. The false positive rate however, has not changed over the last twenty years. Given the variation that exists in both practice and research, the uncertainty regarding the quality of the underlying evidence, there is a clear need for comprehensive, systematic and quantitative overviews of the diagnostic value of the various tests purported to be predictive of acute appendicitis.</p< <p<Methods</p< <p<Literature will be identified searching general bibliographic databases (MEDLINE and EMBASE), specialist computer databases (DARE, Cochrane Database of Systematic Reviews, conference proceedings, MEDION, SCISEARCH, BIOSIS) without language restrictions. We will contact experts and the manufacturers of tests. Hand-searching will complete our searches. Identified articles will be selected according to populations, tests, outcomes and study design. Papers meeting the selection criteria will be appraised to rate their methodological quality. Analysis will include exploration of heterogeneity in results. We will conduct meta-analyses to generate summary estimates of test accuracy measures and summary ROC curves where appropriate. If meta-analysis is considered to be inappropriate, we will describe the identified evidence in the context of appraised quality.</p< <p<Discussion</p< <p<These reviews should lead to formulation of recommendations for current practice and future research.</p< Surgery Bischofberger Stephan A verfasserin aut Bischof Dominique B verfasserin aut Bachmann Lucas M verfasserin aut Osann Franziska M verfasserin aut Steurer Johann verfasserin aut In BMC Surgery BMC, 2003 2(2002), 1, p 2 (DE-627)331018837 (DE-600)2050442-1 14712482 nnns volume:2 year:2002 number:1, p 2 https://doi.org/10.1186/1471-2482-2-2 kostenfrei https://doaj.org/article/b751a7de7cb54491a56e91fcb3af6aef kostenfrei http://www.biomedcentral.com/1471-2482/2/2 kostenfrei https://doaj.org/toc/1471-2482 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2002 1, p 2
allfieldsSound	10.1186/1471-2482-2-2 doi (DE-627)DOAJ076915867 (DE-599)DOAJb751a7de7cb54491a56e91fcb3af6aef DE-627 ger DE-627 rakwb eng RD1-811 Bonani Marco G verfasserin aut Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk and entail a serious waste of resources. Several highly accurate tests have been introduced to diagnose acute appendicitis. The false positive rate however, has not changed over the last twenty years. Given the variation that exists in both practice and research, the uncertainty regarding the quality of the underlying evidence, there is a clear need for comprehensive, systematic and quantitative overviews of the diagnostic value of the various tests purported to be predictive of acute appendicitis.</p< <p<Methods</p< <p<Literature will be identified searching general bibliographic databases (MEDLINE and EMBASE), specialist computer databases (DARE, Cochrane Database of Systematic Reviews, conference proceedings, MEDION, SCISEARCH, BIOSIS) without language restrictions. We will contact experts and the manufacturers of tests. Hand-searching will complete our searches. Identified articles will be selected according to populations, tests, outcomes and study design. Papers meeting the selection criteria will be appraised to rate their methodological quality. Analysis will include exploration of heterogeneity in results. We will conduct meta-analyses to generate summary estimates of test accuracy measures and summary ROC curves where appropriate. If meta-analysis is considered to be inappropriate, we will describe the identified evidence in the context of appraised quality.</p< <p<Discussion</p< <p<These reviews should lead to formulation of recommendations for current practice and future research.</p< Surgery Bischofberger Stephan A verfasserin aut Bischof Dominique B verfasserin aut Bachmann Lucas M verfasserin aut Osann Franziska M verfasserin aut Steurer Johann verfasserin aut In BMC Surgery BMC, 2003 2(2002), 1, p 2 (DE-627)331018837 (DE-600)2050442-1 14712482 nnns volume:2 year:2002 number:1, p 2 https://doi.org/10.1186/1471-2482-2-2 kostenfrei https://doaj.org/article/b751a7de7cb54491a56e91fcb3af6aef kostenfrei http://www.biomedcentral.com/1471-2482/2/2 kostenfrei https://doaj.org/toc/1471-2482 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2 2002 1, p 2
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author	Bonani Marco G
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topic_title	RD1-811 Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol
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title	Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol
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title_full	Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol
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author_browse	Bonani Marco G Bischofberger Stephan A Bischof Dominique B Bachmann Lucas M Osann Franziska M Steurer Johann
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title_sort	systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol
callnumber	RD1-811
title_auth	Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol
abstract	<p<Abstract</p< <p<Background</p< <p<Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk and entail a serious waste of resources. Several highly accurate tests have been introduced to diagnose acute appendicitis. The false positive rate however, has not changed over the last twenty years. Given the variation that exists in both practice and research, the uncertainty regarding the quality of the underlying evidence, there is a clear need for comprehensive, systematic and quantitative overviews of the diagnostic value of the various tests purported to be predictive of acute appendicitis.</p< <p<Methods</p< <p<Literature will be identified searching general bibliographic databases (MEDLINE and EMBASE), specialist computer databases (DARE, Cochrane Database of Systematic Reviews, conference proceedings, MEDION, SCISEARCH, BIOSIS) without language restrictions. We will contact experts and the manufacturers of tests. Hand-searching will complete our searches. Identified articles will be selected according to populations, tests, outcomes and study design. Papers meeting the selection criteria will be appraised to rate their methodological quality. Analysis will include exploration of heterogeneity in results. We will conduct meta-analyses to generate summary estimates of test accuracy measures and summary ROC curves where appropriate. If meta-analysis is considered to be inappropriate, we will describe the identified evidence in the context of appraised quality.</p< <p<Discussion</p< <p<These reviews should lead to formulation of recommendations for current practice and future research.</p<
abstractGer	<p<Abstract</p< <p<Background</p< <p<Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk and entail a serious waste of resources. Several highly accurate tests have been introduced to diagnose acute appendicitis. The false positive rate however, has not changed over the last twenty years. Given the variation that exists in both practice and research, the uncertainty regarding the quality of the underlying evidence, there is a clear need for comprehensive, systematic and quantitative overviews of the diagnostic value of the various tests purported to be predictive of acute appendicitis.</p< <p<Methods</p< <p<Literature will be identified searching general bibliographic databases (MEDLINE and EMBASE), specialist computer databases (DARE, Cochrane Database of Systematic Reviews, conference proceedings, MEDION, SCISEARCH, BIOSIS) without language restrictions. We will contact experts and the manufacturers of tests. Hand-searching will complete our searches. Identified articles will be selected according to populations, tests, outcomes and study design. Papers meeting the selection criteria will be appraised to rate their methodological quality. Analysis will include exploration of heterogeneity in results. We will conduct meta-analyses to generate summary estimates of test accuracy measures and summary ROC curves where appropriate. If meta-analysis is considered to be inappropriate, we will describe the identified evidence in the context of appraised quality.</p< <p<Discussion</p< <p<These reviews should lead to formulation of recommendations for current practice and future research.</p<
abstract_unstemmed	<p<Abstract</p< <p<Background</p< <p<Suspected acute appendicitis is the most frequent cause for emergency operations in visceral surgery worldwide. In approximately twenty percent of all cases however, the diagnosis is incorrect and patients undergo surgery without having acute appendicitis. Operations of bland appendices put patients at risk and entail a serious waste of resources. Several highly accurate tests have been introduced to diagnose acute appendicitis. The false positive rate however, has not changed over the last twenty years. Given the variation that exists in both practice and research, the uncertainty regarding the quality of the underlying evidence, there is a clear need for comprehensive, systematic and quantitative overviews of the diagnostic value of the various tests purported to be predictive of acute appendicitis.</p< <p<Methods</p< <p<Literature will be identified searching general bibliographic databases (MEDLINE and EMBASE), specialist computer databases (DARE, Cochrane Database of Systematic Reviews, conference proceedings, MEDION, SCISEARCH, BIOSIS) without language restrictions. We will contact experts and the manufacturers of tests. Hand-searching will complete our searches. Identified articles will be selected according to populations, tests, outcomes and study design. Papers meeting the selection criteria will be appraised to rate their methodological quality. Analysis will include exploration of heterogeneity in results. We will conduct meta-analyses to generate summary estimates of test accuracy measures and summary ROC curves where appropriate. If meta-analysis is considered to be inappropriate, we will describe the identified evidence in the context of appraised quality.</p< <p<Discussion</p< <p<These reviews should lead to formulation of recommendations for current practice and future research.</p<
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title_short	Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol
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Systematic quantitative overviews of the literature to determine the value of diagnostic tests for predicting acute appendicitis: study protocol

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