Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital

Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestas...
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Autor*in:	Alphonsus N. Onyiriuka [verfasserIn] Kayode A. Adeniran [verfasserIn] Eucharia P.A. Onyiriuka [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2012

Schlagwörter:	Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome.

Übergeordnetes Werk:	In: Oman Medical Journal - Oman Medical Specialty Board, 2010, 27(2012), 4, Seite 329-332
Übergeordnetes Werk:	volume:27 ; year:2012 ; number:4 ; pages:329-332

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ077094948

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520			\|a Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age.
650		4	\|a Hypoglycemia
650		4	\|a Cholestasis
650		4	\|a Infancy
650		4	\|a Neonatal cholestasis syndrome.
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allfields	(DE-627)DOAJ077094948 (DE-599)DOAJ7843e8d651264f2cad94fd9fc4de88f8 DE-627 ger DE-627 rakwb eng Alphonsus N. Onyiriuka verfasserin aut Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age. Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome. Medicine R Kayode A. Adeniran verfasserin aut Eucharia P.A. Onyiriuka verfasserin aut In Oman Medical Journal Oman Medical Specialty Board, 2010 27(2012), 4, Seite 329-332 (DE-627)634755838 (DE-600)2571431-4 20705204 nnns volume:27 year:2012 number:4 pages:329-332 https://doaj.org/article/7843e8d651264f2cad94fd9fc4de88f8 kostenfrei http://www.omjournal.org/fultext_PDF.aspx?DetailsID=273&type=fultext kostenfrei https://doaj.org/toc/1999-768X Journal toc kostenfrei https://doaj.org/toc/2070-5204 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 27 2012 4 329-332
spelling	(DE-627)DOAJ077094948 (DE-599)DOAJ7843e8d651264f2cad94fd9fc4de88f8 DE-627 ger DE-627 rakwb eng Alphonsus N. Onyiriuka verfasserin aut Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age. Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome. Medicine R Kayode A. Adeniran verfasserin aut Eucharia P.A. Onyiriuka verfasserin aut In Oman Medical Journal Oman Medical Specialty Board, 2010 27(2012), 4, Seite 329-332 (DE-627)634755838 (DE-600)2571431-4 20705204 nnns volume:27 year:2012 number:4 pages:329-332 https://doaj.org/article/7843e8d651264f2cad94fd9fc4de88f8 kostenfrei http://www.omjournal.org/fultext_PDF.aspx?DetailsID=273&type=fultext kostenfrei https://doaj.org/toc/1999-768X Journal toc kostenfrei https://doaj.org/toc/2070-5204 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 27 2012 4 329-332
allfields_unstemmed	(DE-627)DOAJ077094948 (DE-599)DOAJ7843e8d651264f2cad94fd9fc4de88f8 DE-627 ger DE-627 rakwb eng Alphonsus N. Onyiriuka verfasserin aut Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age. Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome. Medicine R Kayode A. Adeniran verfasserin aut Eucharia P.A. Onyiriuka verfasserin aut In Oman Medical Journal Oman Medical Specialty Board, 2010 27(2012), 4, Seite 329-332 (DE-627)634755838 (DE-600)2571431-4 20705204 nnns volume:27 year:2012 number:4 pages:329-332 https://doaj.org/article/7843e8d651264f2cad94fd9fc4de88f8 kostenfrei http://www.omjournal.org/fultext_PDF.aspx?DetailsID=273&type=fultext kostenfrei https://doaj.org/toc/1999-768X Journal toc kostenfrei https://doaj.org/toc/2070-5204 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 27 2012 4 329-332
allfieldsGer	(DE-627)DOAJ077094948 (DE-599)DOAJ7843e8d651264f2cad94fd9fc4de88f8 DE-627 ger DE-627 rakwb eng Alphonsus N. Onyiriuka verfasserin aut Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age. Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome. Medicine R Kayode A. Adeniran verfasserin aut Eucharia P.A. Onyiriuka verfasserin aut In Oman Medical Journal Oman Medical Specialty Board, 2010 27(2012), 4, Seite 329-332 (DE-627)634755838 (DE-600)2571431-4 20705204 nnns volume:27 year:2012 number:4 pages:329-332 https://doaj.org/article/7843e8d651264f2cad94fd9fc4de88f8 kostenfrei http://www.omjournal.org/fultext_PDF.aspx?DetailsID=273&type=fultext kostenfrei https://doaj.org/toc/1999-768X Journal toc kostenfrei https://doaj.org/toc/2070-5204 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 27 2012 4 329-332
allfieldsSound	(DE-627)DOAJ077094948 (DE-599)DOAJ7843e8d651264f2cad94fd9fc4de88f8 DE-627 ger DE-627 rakwb eng Alphonsus N. Onyiriuka verfasserin aut Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age. Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome. Medicine R Kayode A. Adeniran verfasserin aut Eucharia P.A. Onyiriuka verfasserin aut In Oman Medical Journal Oman Medical Specialty Board, 2010 27(2012), 4, Seite 329-332 (DE-627)634755838 (DE-600)2571431-4 20705204 nnns volume:27 year:2012 number:4 pages:329-332 https://doaj.org/article/7843e8d651264f2cad94fd9fc4de88f8 kostenfrei http://www.omjournal.org/fultext_PDF.aspx?DetailsID=273&type=fultext kostenfrei https://doaj.org/toc/1999-768X Journal toc kostenfrei https://doaj.org/toc/2070-5204 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 27 2012 4 329-332
language	English
source	In Oman Medical Journal 27(2012), 4, Seite 329-332 volume:27 year:2012 number:4 pages:329-332
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topic_facet	Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome. Medicine R
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Onyiriuka</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2012</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. 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author	Alphonsus N. Onyiriuka
spellingShingle	Alphonsus N. Onyiriuka misc Hypoglycemia misc Cholestasis misc Infancy misc Neonatal cholestasis syndrome. misc Medicine misc R Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital
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topic_title	Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital Hypoglycemia Cholestasis Infancy Neonatal cholestasis syndrome
topic	misc Hypoglycemia misc Cholestasis misc Infancy misc Neonatal cholestasis syndrome. misc Medicine misc R
topic_unstemmed	misc Hypoglycemia misc Cholestasis misc Infancy misc Neonatal cholestasis syndrome. misc Medicine misc R
topic_browse	misc Hypoglycemia misc Cholestasis misc Infancy misc Neonatal cholestasis syndrome. misc Medicine misc R
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title	Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital
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title_full	Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital
author_sort	Alphonsus N. Onyiriuka
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author_browse	Alphonsus N. Onyiriuka Kayode A. Adeniran Eucharia P.A. Onyiriuka
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author-letter	Alphonsus N. Onyiriuka
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title_sort	prevalence of hypoglycemia among patients presenting with cholestasis of infancy in a nigerian teaching hospital
title_auth	Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital
abstract	Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age.
abstractGer	Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age.
abstract_unstemmed	Objective: This study assesses the prevalence of hypoglycemia among patients presenting at the University of Benin Teaching Hospital, Benin City, Nigeria with cholestasis of infancy.Methods: During a period of five years, forty patients aged between 15 days and 12 months who presented with cholestasis of infancy, were admitted and screened for hypoglycemia, using Accutrend glucometer. For patients with low blood glucose values, blood samples were further analyzed, using the standard glucose-oxidase method.Results: Of the 2,835 patients admitted over a five-year period, 40 (1.4%) had cholestasis of infancy, giving an incidence of 14 cases per 1000 admissions, with a sex ratio of 2.1: 1 in favour of males. Nine (22.5%) of the 40 infants with cholestasis had at least one blood glucose concentration less than 2.6 mmol/L (hypoglycemia). Of the nine hypoglycemic infants, three (33.3%) had one blood glucose concentration less than 1.6 mmol/L (severe hypoglycemia). Seven (77.8%) of the nine hypoglycemic infants were diagnosed in the first 36 hours of admission. Lethargy and poor feeding were observed in three infants with severe hypoglycemia and three of them died. Six (66.7%) of the hypoglycemic infants were below 3 months of age.Conclusions: Hypoglycemia was observed among patients with cholestasis of infancy and the prevalence was higher among infants below 3 months of age.
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title_short	Prevalence of Hypoglycemia Among Patients Presenting with Cholestasis of Infancy in a Nigerian Teaching Hospital
url	https://doaj.org/article/7843e8d651264f2cad94fd9fc4de88f8 http://www.omjournal.org/fultext_PDF.aspx?DetailsID=273&type=fultext https://doaj.org/toc/1999-768X https://doaj.org/toc/2070-5204
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up_date	2024-07-03T23:52:30.007Z
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