Herd Protection against Meningococcal Disease through Vaccination

Reduction in the transmission of <i<Neisseria meningitidis</i< within a population results in fewer invasive disease cases. Vaccination with meningococcal vaccines composed of high weight capsular polysaccharide without carrier proteins has minimal effect against carriage or the acquisit...
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Gespeichert in:

Autor*in:	Stephen A. Clark [verfasserIn] Ray Borrow [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	meningococcal infection meningococcal incidence invasive meningococcal disease (IMD) IMD epidemiology meningococcal vaccine

Übergeordnetes Werk:	In: Microorganisms - MDPI AG, 2013, 8(2020), 11, p 1675
Übergeordnetes Werk:	volume:8 ; year:2020 ; number:11, p 1675

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/microorganisms8111675

Katalog-ID:	DOAJ077149343

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spelling	10.3390/microorganisms8111675 doi (DE-627)DOAJ077149343 (DE-599)DOAJ34a1364d8d95464fbb4e4dea02d16b13 DE-627 ger DE-627 rakwb eng QH301-705.5 Stephen A. Clark verfasserin aut Herd Protection against Meningococcal Disease through Vaccination 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Reduction in the transmission of <i<Neisseria meningitidis</i< within a population results in fewer invasive disease cases. Vaccination with meningococcal vaccines composed of high weight capsular polysaccharide without carrier proteins has minimal effect against carriage or the acquisition of carriage. Conjugate vaccines, however, elicit an enhanced immune response which serves to reduce carriage acquisition and hinder onwards transmission. Since the 1990s, several meningococcal conjugate vaccines have been developed and, when used in age groups associated with higher carriage, they have been shown to provide indirect protection to unvaccinated cohorts. This herd protective effect is important in enhancing the efficiency and impact of vaccination. Studies are ongoing to assess the effect of protein-based group B vaccines on carriage; however, current data cast doubt on their ability to reduce transmission. <i<Neisseria meningitidis</i< meningococcal infection meningococcal incidence invasive meningococcal disease (IMD) IMD epidemiology meningococcal vaccine Biology (General) Ray Borrow verfasserin aut In Microorganisms MDPI AG, 2013 8(2020), 11, p 1675 (DE-627)750370696 (DE-600)2720891-6 20762607 nnns volume:8 year:2020 number:11, p 1675 https://doi.org/10.3390/microorganisms8111675 kostenfrei https://doaj.org/article/34a1364d8d95464fbb4e4dea02d16b13 kostenfrei https://www.mdpi.com/2076-2607/8/11/1675 kostenfrei https://doaj.org/toc/2076-2607 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2020 11, p 1675
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author	Stephen A. Clark
spellingShingle	Stephen A. Clark misc QH301-705.5 misc <i<Neisseria meningitidis</i< misc meningococcal infection misc meningococcal incidence misc invasive meningococcal disease (IMD) misc IMD epidemiology misc meningococcal vaccine misc Biology (General) Herd Protection against Meningococcal Disease through Vaccination
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topic_title	QH301-705.5 Herd Protection against Meningococcal Disease through Vaccination <i<Neisseria meningitidis</i< meningococcal infection meningococcal incidence invasive meningococcal disease (IMD) IMD epidemiology meningococcal vaccine
topic	misc QH301-705.5 misc <i<Neisseria meningitidis</i< misc meningococcal infection misc meningococcal incidence misc invasive meningococcal disease (IMD) misc IMD epidemiology misc meningococcal vaccine misc Biology (General)
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title	Herd Protection against Meningococcal Disease through Vaccination
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title_sort	herd protection against meningococcal disease through vaccination
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title_auth	Herd Protection against Meningococcal Disease through Vaccination
abstract	Reduction in the transmission of <i<Neisseria meningitidis</i< within a population results in fewer invasive disease cases. Vaccination with meningococcal vaccines composed of high weight capsular polysaccharide without carrier proteins has minimal effect against carriage or the acquisition of carriage. Conjugate vaccines, however, elicit an enhanced immune response which serves to reduce carriage acquisition and hinder onwards transmission. Since the 1990s, several meningococcal conjugate vaccines have been developed and, when used in age groups associated with higher carriage, they have been shown to provide indirect protection to unvaccinated cohorts. This herd protective effect is important in enhancing the efficiency and impact of vaccination. Studies are ongoing to assess the effect of protein-based group B vaccines on carriage; however, current data cast doubt on their ability to reduce transmission.
abstractGer	Reduction in the transmission of <i<Neisseria meningitidis</i< within a population results in fewer invasive disease cases. Vaccination with meningococcal vaccines composed of high weight capsular polysaccharide without carrier proteins has minimal effect against carriage or the acquisition of carriage. Conjugate vaccines, however, elicit an enhanced immune response which serves to reduce carriage acquisition and hinder onwards transmission. Since the 1990s, several meningococcal conjugate vaccines have been developed and, when used in age groups associated with higher carriage, they have been shown to provide indirect protection to unvaccinated cohorts. This herd protective effect is important in enhancing the efficiency and impact of vaccination. Studies are ongoing to assess the effect of protein-based group B vaccines on carriage; however, current data cast doubt on their ability to reduce transmission.
abstract_unstemmed	Reduction in the transmission of <i<Neisseria meningitidis</i< within a population results in fewer invasive disease cases. Vaccination with meningococcal vaccines composed of high weight capsular polysaccharide without carrier proteins has minimal effect against carriage or the acquisition of carriage. Conjugate vaccines, however, elicit an enhanced immune response which serves to reduce carriage acquisition and hinder onwards transmission. Since the 1990s, several meningococcal conjugate vaccines have been developed and, when used in age groups associated with higher carriage, they have been shown to provide indirect protection to unvaccinated cohorts. This herd protective effect is important in enhancing the efficiency and impact of vaccination. Studies are ongoing to assess the effect of protein-based group B vaccines on carriage; however, current data cast doubt on their ability to reduce transmission.
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title_short	Herd Protection against Meningococcal Disease through Vaccination
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