Histometric study of socket healing after tooth extraction in rats treated with diclofenac

The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Yugoshi Luciana Ibara [verfasserIn] Sala Miguel Angel [verfasserIn] Brentegani Luiz Guilherme [verfasserIn] Carvalho Teresa Lúcia Lamano [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2002

Schlagwörter:	diclofenac socket healing tooth extraction

Übergeordnetes Werk:	In: Brazilian Dental Journal - Fundação Odontológica de Ribeirão Preto, 2017, 13(2002), 2, Seite 92-96
Übergeordnetes Werk:	volume:13 ; year:2002 ; number:2 ; pages:92-96

Links:	Link aufrufen Link aufrufen Journal toc

Katalog-ID:	DOAJ077250761

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spelling	(DE-627)DOAJ077250761 (DE-599)DOAJ45bb2717262b40cd9482730eed11d223 DE-627 ger DE-627 rakwb eng RK1-715 Yugoshi Luciana Ibara verfasserin aut Histometric study of socket healing after tooth extraction in rats treated with diclofenac 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization. diclofenac socket healing tooth extraction Dentistry Sala Miguel Angel verfasserin aut Brentegani Luiz Guilherme verfasserin aut Carvalho Teresa Lúcia Lamano verfasserin aut In Brazilian Dental Journal Fundação Odontológica de Ribeirão Preto, 2017 13(2002), 2, Seite 92-96 (DE-627)269532730 (DE-600)1474817-4 18064760 nnns volume:13 year:2002 number:2 pages:92-96 https://doaj.org/article/45bb2717262b40cd9482730eed11d223 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402002000200003 kostenfrei https://doaj.org/toc/0103-6440 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2002 2 92-96
allfields_unstemmed	(DE-627)DOAJ077250761 (DE-599)DOAJ45bb2717262b40cd9482730eed11d223 DE-627 ger DE-627 rakwb eng RK1-715 Yugoshi Luciana Ibara verfasserin aut Histometric study of socket healing after tooth extraction in rats treated with diclofenac 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization. diclofenac socket healing tooth extraction Dentistry Sala Miguel Angel verfasserin aut Brentegani Luiz Guilherme verfasserin aut Carvalho Teresa Lúcia Lamano verfasserin aut In Brazilian Dental Journal Fundação Odontológica de Ribeirão Preto, 2017 13(2002), 2, Seite 92-96 (DE-627)269532730 (DE-600)1474817-4 18064760 nnns volume:13 year:2002 number:2 pages:92-96 https://doaj.org/article/45bb2717262b40cd9482730eed11d223 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402002000200003 kostenfrei https://doaj.org/toc/0103-6440 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2002 2 92-96
allfieldsGer	(DE-627)DOAJ077250761 (DE-599)DOAJ45bb2717262b40cd9482730eed11d223 DE-627 ger DE-627 rakwb eng RK1-715 Yugoshi Luciana Ibara verfasserin aut Histometric study of socket healing after tooth extraction in rats treated with diclofenac 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization. diclofenac socket healing tooth extraction Dentistry Sala Miguel Angel verfasserin aut Brentegani Luiz Guilherme verfasserin aut Carvalho Teresa Lúcia Lamano verfasserin aut In Brazilian Dental Journal Fundação Odontológica de Ribeirão Preto, 2017 13(2002), 2, Seite 92-96 (DE-627)269532730 (DE-600)1474817-4 18064760 nnns volume:13 year:2002 number:2 pages:92-96 https://doaj.org/article/45bb2717262b40cd9482730eed11d223 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402002000200003 kostenfrei https://doaj.org/toc/0103-6440 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2002 2 92-96
allfieldsSound	(DE-627)DOAJ077250761 (DE-599)DOAJ45bb2717262b40cd9482730eed11d223 DE-627 ger DE-627 rakwb eng RK1-715 Yugoshi Luciana Ibara verfasserin aut Histometric study of socket healing after tooth extraction in rats treated with diclofenac 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization. diclofenac socket healing tooth extraction Dentistry Sala Miguel Angel verfasserin aut Brentegani Luiz Guilherme verfasserin aut Carvalho Teresa Lúcia Lamano verfasserin aut In Brazilian Dental Journal Fundação Odontológica de Ribeirão Preto, 2017 13(2002), 2, Seite 92-96 (DE-627)269532730 (DE-600)1474817-4 18064760 nnns volume:13 year:2002 number:2 pages:92-96 https://doaj.org/article/45bb2717262b40cd9482730eed11d223 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-64402002000200003 kostenfrei https://doaj.org/toc/0103-6440 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_138 GBV_ILN_151 GBV_ILN_152 GBV_ILN_161 GBV_ILN_170 GBV_ILN_187 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_250 GBV_ILN_281 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_702 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2002 2 92-96
language	English
source	In Brazilian Dental Journal 13(2002), 2, Seite 92-96 volume:13 year:2002 number:2 pages:92-96
sourceStr	In Brazilian Dental Journal 13(2002), 2, Seite 92-96 volume:13 year:2002 number:2 pages:92-96
format_phy_str_mv	Article
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topic_facet	diclofenac socket healing tooth extraction Dentistry
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authorswithroles_txt_mv	Yugoshi Luciana Ibara @@aut@@ Sala Miguel Angel @@aut@@ Brentegani Luiz Guilherme @@aut@@ Carvalho Teresa Lúcia Lamano @@aut@@
publishDateDaySort_date	2002-01-01T00:00:00Z
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callnumber-first	R - Medicine
author	Yugoshi Luciana Ibara
spellingShingle	Yugoshi Luciana Ibara misc RK1-715 misc diclofenac misc socket healing misc tooth extraction misc Dentistry Histometric study of socket healing after tooth extraction in rats treated with diclofenac
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topic_title	RK1-715 Histometric study of socket healing after tooth extraction in rats treated with diclofenac diclofenac socket healing tooth extraction
topic	misc RK1-715 misc diclofenac misc socket healing misc tooth extraction misc Dentistry
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title_full	Histometric study of socket healing after tooth extraction in rats treated with diclofenac
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title_sort	histometric study of socket healing after tooth extraction in rats treated with diclofenac
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title_auth	Histometric study of socket healing after tooth extraction in rats treated with diclofenac
abstract	The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization.
abstractGer	The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization.
abstract_unstemmed	The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization.
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title_short	Histometric study of socket healing after tooth extraction in rats treated with diclofenac
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Histometric study of socket healing after tooth extraction in rats treated with diclofenac

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