A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection

A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the prepar...
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Autor*in:	Po-Chang Wu [verfasserIn] Chao-Ping Pai [verfasserIn] Mon-Juan Lee [verfasserIn] Wei Lee [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	liquid crystal spin-coating single-substrate label-free biosensor bovine serum albumin cancer biomarker CA125

Übergeordnetes Werk:	In: Biosensors - MDPI AG, 2012, 11(2021), 10, p 374
Übergeordnetes Werk:	volume:11 ; year:2021 ; number:10, p 374

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/bios11100374

Katalog-ID:	DOAJ077541472

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520			\|a A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay.
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allfields	10.3390/bios11100374 doi (DE-627)DOAJ077541472 (DE-599)DOAJ0b029b184aa0474c96a30c92eb75562f DE-627 ger DE-627 rakwb eng TP248.13-248.65 Po-Chang Wu verfasserin aut A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay. liquid crystal spin-coating single-substrate label-free biosensor bovine serum albumin cancer biomarker CA125 Biotechnology Chao-Ping Pai verfasserin aut Mon-Juan Lee verfasserin aut Wei Lee verfasserin aut In Biosensors MDPI AG, 2012 11(2021), 10, p 374 (DE-627)718626451 (DE-600)2662125-3 20796374 nnns volume:11 year:2021 number:10, p 374 https://doi.org/10.3390/bios11100374 kostenfrei https://doaj.org/article/0b029b184aa0474c96a30c92eb75562f kostenfrei https://www.mdpi.com/2079-6374/11/10/374 kostenfrei https://doaj.org/toc/2079-6374 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 10, p 374
spelling	10.3390/bios11100374 doi (DE-627)DOAJ077541472 (DE-599)DOAJ0b029b184aa0474c96a30c92eb75562f DE-627 ger DE-627 rakwb eng TP248.13-248.65 Po-Chang Wu verfasserin aut A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay. liquid crystal spin-coating single-substrate label-free biosensor bovine serum albumin cancer biomarker CA125 Biotechnology Chao-Ping Pai verfasserin aut Mon-Juan Lee verfasserin aut Wei Lee verfasserin aut In Biosensors MDPI AG, 2012 11(2021), 10, p 374 (DE-627)718626451 (DE-600)2662125-3 20796374 nnns volume:11 year:2021 number:10, p 374 https://doi.org/10.3390/bios11100374 kostenfrei https://doaj.org/article/0b029b184aa0474c96a30c92eb75562f kostenfrei https://www.mdpi.com/2079-6374/11/10/374 kostenfrei https://doaj.org/toc/2079-6374 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 10, p 374
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allfieldsGer	10.3390/bios11100374 doi (DE-627)DOAJ077541472 (DE-599)DOAJ0b029b184aa0474c96a30c92eb75562f DE-627 ger DE-627 rakwb eng TP248.13-248.65 Po-Chang Wu verfasserin aut A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay. liquid crystal spin-coating single-substrate label-free biosensor bovine serum albumin cancer biomarker CA125 Biotechnology Chao-Ping Pai verfasserin aut Mon-Juan Lee verfasserin aut Wei Lee verfasserin aut In Biosensors MDPI AG, 2012 11(2021), 10, p 374 (DE-627)718626451 (DE-600)2662125-3 20796374 nnns volume:11 year:2021 number:10, p 374 https://doi.org/10.3390/bios11100374 kostenfrei https://doaj.org/article/0b029b184aa0474c96a30c92eb75562f kostenfrei https://www.mdpi.com/2079-6374/11/10/374 kostenfrei https://doaj.org/toc/2079-6374 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 10, p 374
allfieldsSound	10.3390/bios11100374 doi (DE-627)DOAJ077541472 (DE-599)DOAJ0b029b184aa0474c96a30c92eb75562f DE-627 ger DE-627 rakwb eng TP248.13-248.65 Po-Chang Wu verfasserin aut A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay. liquid crystal spin-coating single-substrate label-free biosensor bovine serum albumin cancer biomarker CA125 Biotechnology Chao-Ping Pai verfasserin aut Mon-Juan Lee verfasserin aut Wei Lee verfasserin aut In Biosensors MDPI AG, 2012 11(2021), 10, p 374 (DE-627)718626451 (DE-600)2662125-3 20796374 nnns volume:11 year:2021 number:10, p 374 https://doi.org/10.3390/bios11100374 kostenfrei https://doaj.org/article/0b029b184aa0474c96a30c92eb75562f kostenfrei https://www.mdpi.com/2079-6374/11/10/374 kostenfrei https://doaj.org/toc/2079-6374 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 10, p 374
language	English
source	In Biosensors 11(2021), 10, p 374 volume:11 year:2021 number:10, p 374
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topic_facet	liquid crystal spin-coating single-substrate label-free biosensor bovine serum albumin cancer biomarker CA125 Biotechnology
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authorswithroles_txt_mv	Po-Chang Wu @@aut@@ Chao-Ping Pai @@aut@@ Mon-Juan Lee @@aut@@ Wei Lee @@aut@@
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callnumber-first	T - Technology
author	Po-Chang Wu
spellingShingle	Po-Chang Wu misc TP248.13-248.65 misc liquid crystal misc spin-coating misc single-substrate misc label-free biosensor misc bovine serum albumin misc cancer biomarker CA125 misc Biotechnology A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection
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topic_title	TP248.13-248.65 A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection liquid crystal spin-coating single-substrate label-free biosensor bovine serum albumin cancer biomarker CA125
topic	misc TP248.13-248.65 misc liquid crystal misc spin-coating misc single-substrate misc label-free biosensor misc bovine serum albumin misc cancer biomarker CA125 misc Biotechnology
topic_unstemmed	misc TP248.13-248.65 misc liquid crystal misc spin-coating misc single-substrate misc label-free biosensor misc bovine serum albumin misc cancer biomarker CA125 misc Biotechnology
topic_browse	misc TP248.13-248.65 misc liquid crystal misc spin-coating misc single-substrate misc label-free biosensor misc bovine serum albumin misc cancer biomarker CA125 misc Biotechnology
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title	A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection
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title_full	A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection
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author_browse	Po-Chang Wu Chao-Ping Pai Mon-Juan Lee Wei Lee
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title_sort	single-substrate biosensor with spin-coated liquid crystal film for simple, sensitive and label-free protein detection
callnumber	TP248.13-248.65
title_auth	A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection
abstract	A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay.
abstractGer	A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay.
abstract_unstemmed	A liquid crystal (LC)-based single-substrate biosensor was developed by spin-coating an LC thin film on a dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-decorated glass slide. Compared with the conventional sandwiched cell configuration, the simplified procedure for the preparation of an LC film allows the film thickness to be precisely controlled by adjusting the spin rate, thus eliminating personal errors involved in LC cell assembly. The limit of detection (LOD) for bovine serum albumin (BSA) was lowered from 10<sup<−5</sup< g/mL with a 4.2-μm-thick sandwiched cell of the commercial LC E7 to 10<sup<−</sup<<sup<7</sup< g/mL with a 4.2-μm-thick spin-coated E7 film and further to 10<sup<−</sup<<sup<8</sup< g/mL by reducing the E7 film thickness to 3.4 μm. Moreover, by exploiting the LC film of the highly birefringent nematic LC HDN in the immunodetection of the cancer biomarker CA125, an LOD comparable to that determined with a sandwiched HDN cell was achieved at 10<sup<−8</sup< g/mL CA125 using a capture antibody concentration an order of magnitude lower than that in the LC cell. Our results suggest that employing spin-coated LC film instead of conventional sandwiched LC cell provides a more reliable, reproducible, and cost-effective single-substrate platform, allowing simple fabrication of an LC-based biosensor for sensitive and label-free protein detection and immunoassay.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	10, p 374
title_short	A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection
url	https://doi.org/10.3390/bios11100374 https://doaj.org/article/0b029b184aa0474c96a30c92eb75562f https://www.mdpi.com/2079-6374/11/10/374 https://doaj.org/toc/2079-6374
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A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection

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