Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease and adult lung spheroid cells have been shown to promote regeneration in animal models of IPF. Here the authors show that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury...
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Autor*in:	Phuong-Uyen C. Dinh [verfasserIn] Dipti Paudel [verfasserIn] Hayden Brochu [verfasserIn] Kristen D. Popowski [verfasserIn] M. Cyndell Gracieux [verfasserIn] Jhon Cores [verfasserIn] Ke Huang [verfasserIn] M. Taylor Hensley [verfasserIn] Erin Harrell [verfasserIn] Adam C. Vandergriff [verfasserIn] Arianna K. George [verfasserIn] Raina T. Barrio [verfasserIn] Shiqi Hu [verfasserIn] Tyler A. Allen [verfasserIn] Kevin Blackburn [verfasserIn] Thomas G. Caranasos [verfasserIn] Xinxia Peng [verfasserIn] Lauren V. Schnabel [verfasserIn] Kenneth B. Adler [verfasserIn] Leonard J. Lobo [verfasserIn] Michael B. Goshe [verfasserIn] Ke Cheng [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 11(2020), 1, Seite 14
Übergeordnetes Werk:	volume:11 ; year:2020 ; number:1 ; pages:14

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-020-14344-7

Katalog-ID:	DOAJ077567366

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authorswithroles_txt_mv	Phuong-Uyen C. Dinh @@aut@@ Dipti Paudel @@aut@@ Hayden Brochu @@aut@@ Kristen D. Popowski @@aut@@ M. Cyndell Gracieux @@aut@@ Jhon Cores @@aut@@ Ke Huang @@aut@@ M. Taylor Hensley @@aut@@ Erin Harrell @@aut@@ Adam C. Vandergriff @@aut@@ Arianna K. George @@aut@@ Raina T. Barrio @@aut@@ Shiqi Hu @@aut@@ Tyler A. Allen @@aut@@ Kevin Blackburn @@aut@@ Thomas G. Caranasos @@aut@@ Xinxia Peng @@aut@@ Lauren V. Schnabel @@aut@@ Kenneth B. Adler @@aut@@ Leonard J. Lobo @@aut@@ Michael B. Goshe @@aut@@ Ke Cheng @@aut@@
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author	Phuong-Uyen C. Dinh
spellingShingle	Phuong-Uyen C. Dinh misc Science misc Q Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
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topic_title	Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
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title	Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
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title_full	Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
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author_browse	Phuong-Uyen C. Dinh Dipti Paudel Hayden Brochu Kristen D. Popowski M. Cyndell Gracieux Jhon Cores Ke Huang M. Taylor Hensley Erin Harrell Adam C. Vandergriff Arianna K. George Raina T. Barrio Shiqi Hu Tyler A. Allen Kevin Blackburn Thomas G. Caranasos Xinxia Peng Lauren V. Schnabel Kenneth B. Adler Leonard J. Lobo Michael B. Goshe Ke Cheng
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title_sort	inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
title_auth	Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
abstract	Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease and adult lung spheroid cells have been shown to promote regeneration in animal models of IPF. Here the authors show that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells.
abstractGer	Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease and adult lung spheroid cells have been shown to promote regeneration in animal models of IPF. Here the authors show that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells.
abstract_unstemmed	Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease and adult lung spheroid cells have been shown to promote regeneration in animal models of IPF. Here the authors show that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells.
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title_short	Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
url	https://doi.org/10.1038/s41467-020-14344-7 https://doaj.org/article/4496cdf678834d70ba8a9b30f7098a55 https://doaj.org/toc/2041-1723
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up_date	2024-07-04T01:43:15.242Z
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