AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN
Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the ac...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Triana Riandani Djamhuri [verfasserIn] Yuliet Yuliet [verfasserIn] Khildah Khaerati [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch ; Indonesisch |
| Erschienen: |
2016 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) - Universitas Tadulako, 2018, 2(2016), 1, Seite 31-37 |
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| Übergeordnetes Werk: |
volume:2 ; year:2016 ; number:1 ; pages:31-37 |
| Links: |
Link aufrufen |
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| DOI / URN: |
10.22487/j24428744.2016.v2.i1.5303 |
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| Katalog-ID: |
DOAJ077610997 |
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| 520 | |a Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW | ||
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10.22487/j24428744.2016.v2.i1.5303 doi (DE-627)DOAJ077610997 (DE-599)DOAJ1a3a71eecf3a442e9b1dd99b46ca5a32 DE-627 ger DE-627 rakwb eng ind RM1-950 Triana Riandani Djamhuri verfasserin aut AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW Abelmoschus moscathus Medik Antinefrolithiasis Kidney weight ratio Levels of calcium Therapeutics. Pharmacology Yuliet Yuliet verfasserin aut Khildah Khaerati verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 2(2016), 1, Seite 31-37 (DE-627)1760615722 24428744 nnns volume:2 year:2016 number:1 pages:31-37 https://doi.org/10.22487/j24428744.2016.v2.i1.5303 kostenfrei https://doaj.org/article/1a3a71eecf3a442e9b1dd99b46ca5a32 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/5303 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2 2016 1 31-37 |
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10.22487/j24428744.2016.v2.i1.5303 doi (DE-627)DOAJ077610997 (DE-599)DOAJ1a3a71eecf3a442e9b1dd99b46ca5a32 DE-627 ger DE-627 rakwb eng ind RM1-950 Triana Riandani Djamhuri verfasserin aut AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW Abelmoschus moscathus Medik Antinefrolithiasis Kidney weight ratio Levels of calcium Therapeutics. Pharmacology Yuliet Yuliet verfasserin aut Khildah Khaerati verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 2(2016), 1, Seite 31-37 (DE-627)1760615722 24428744 nnns volume:2 year:2016 number:1 pages:31-37 https://doi.org/10.22487/j24428744.2016.v2.i1.5303 kostenfrei https://doaj.org/article/1a3a71eecf3a442e9b1dd99b46ca5a32 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/5303 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2 2016 1 31-37 |
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10.22487/j24428744.2016.v2.i1.5303 doi (DE-627)DOAJ077610997 (DE-599)DOAJ1a3a71eecf3a442e9b1dd99b46ca5a32 DE-627 ger DE-627 rakwb eng ind RM1-950 Triana Riandani Djamhuri verfasserin aut AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW Abelmoschus moscathus Medik Antinefrolithiasis Kidney weight ratio Levels of calcium Therapeutics. Pharmacology Yuliet Yuliet verfasserin aut Khildah Khaerati verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 2(2016), 1, Seite 31-37 (DE-627)1760615722 24428744 nnns volume:2 year:2016 number:1 pages:31-37 https://doi.org/10.22487/j24428744.2016.v2.i1.5303 kostenfrei https://doaj.org/article/1a3a71eecf3a442e9b1dd99b46ca5a32 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/5303 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2 2016 1 31-37 |
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10.22487/j24428744.2016.v2.i1.5303 doi (DE-627)DOAJ077610997 (DE-599)DOAJ1a3a71eecf3a442e9b1dd99b46ca5a32 DE-627 ger DE-627 rakwb eng ind RM1-950 Triana Riandani Djamhuri verfasserin aut AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW Abelmoschus moscathus Medik Antinefrolithiasis Kidney weight ratio Levels of calcium Therapeutics. Pharmacology Yuliet Yuliet verfasserin aut Khildah Khaerati verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 2(2016), 1, Seite 31-37 (DE-627)1760615722 24428744 nnns volume:2 year:2016 number:1 pages:31-37 https://doi.org/10.22487/j24428744.2016.v2.i1.5303 kostenfrei https://doaj.org/article/1a3a71eecf3a442e9b1dd99b46ca5a32 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/5303 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2 2016 1 31-37 |
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10.22487/j24428744.2016.v2.i1.5303 doi (DE-627)DOAJ077610997 (DE-599)DOAJ1a3a71eecf3a442e9b1dd99b46ca5a32 DE-627 ger DE-627 rakwb eng ind RM1-950 Triana Riandani Djamhuri verfasserin aut AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW Abelmoschus moscathus Medik Antinefrolithiasis Kidney weight ratio Levels of calcium Therapeutics. Pharmacology Yuliet Yuliet verfasserin aut Khildah Khaerati verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 2(2016), 1, Seite 31-37 (DE-627)1760615722 24428744 nnns volume:2 year:2016 number:1 pages:31-37 https://doi.org/10.22487/j24428744.2016.v2.i1.5303 kostenfrei https://doaj.org/article/1a3a71eecf3a442e9b1dd99b46ca5a32 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/5303 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2 2016 1 31-37 |
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AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN |
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aktivitas penghambatan pembentukan batu ginjal (antinefrolithiasis) ekstrak etanol daun gedi merah (abelmoschus moschtus medik) pada tikus putih jantan |
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AKTIVITAS PENGHAMBATAN PEMBENTUKAN BATU GINJAL (Antinefrolithiasis) EKSTRAK ETANOL DAUN GEDI MERAH (Abelmoschus moschtus Medik) PADA TIKUS PUTIH JANTAN |
| abstract |
Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW |
| abstractGer |
Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW |
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Red Gedi (Abelmoschus moschatus Medik) is a plant found only in tropical climate areas such as Africa and Asia. Some people’s experience in Manado stated that red gedi plants can be used to treat various types of disease, one of them was kidney stones. Therefore, this study aimed to determine the activity and the effective dose of red gedi leaf extract as an inhibitor of kidney stone formation. The extract was prepared by maceration using ethanol 96%. Inhibitory activity test of kidney stone formation was done by firstly dividing the labrats into 6 groups. Each group consisted of 3 male rats. Both the first group (Normal control) and the second group (Negative control) weregiven Na.CMC 0.5%; the third group (Positive control) was given Batugin Elixir at a dose of 2.7 ml/kgBW; while the fourth, fifth, and sixth were respectively given red gedileaf extract at doses of 50, 100, and 150 mg/kgBW. After 2 hours, all treatment groups were induced with0.75% of ethylene glycol and 2% of ammonium chloride except for the normal control. Ratio of kidney weight and the level of calcium were then measured and calculated. Data obtained were statistically analyzed using ANOVA (Analysis Of variance) and continued with LSD (Least Significantly Difference). It can be concluded that ethanol extract of red gedileaves had inhibitory activity of kidney stones formation in all dose variation and the most effective one was at a dose of 150 mg/kgBW |
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