Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery

Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial...
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Autor*in:	Michał Jan Stasiowski [verfasserIn] Izabela Szumera [verfasserIn] Piotr Wardas [verfasserIn] Seweryn Król [verfasserIn] Jakub Żak [verfasserIn] Anna Missir [verfasserIn] Aleksandra Pluta [verfasserIn] Ewa Niewiadomska [verfasserIn] Lech Krawczyk [verfasserIn] Przemysław Jałowiecki [verfasserIn] Beniamin Oskar Grabarek [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field

Übergeordnetes Werk:	In: Journal of Clinical Medicine - MDPI AG, 2013, 10(2021), 20, p 4683
Übergeordnetes Werk:	volume:10 ; year:2021 ; number:20, p 4683

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/jcm10204683

Katalog-ID:	DOAJ077683609

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520			\|a Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room.
650		4	\|a surgical pleth index
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allfields	10.3390/jcm10204683 doi (DE-627)DOAJ077683609 (DE-599)DOAJ7863746a7370491ba304619fc1dc32d2 DE-627 ger DE-627 rakwb eng Michał Jan Stasiowski verfasserin aut Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room. surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field Medicine R Izabela Szumera verfasserin aut Piotr Wardas verfasserin aut Seweryn Król verfasserin aut Jakub Żak verfasserin aut Anna Missir verfasserin aut Aleksandra Pluta verfasserin aut Ewa Niewiadomska verfasserin aut Lech Krawczyk verfasserin aut Przemysław Jałowiecki verfasserin aut Beniamin Oskar Grabarek verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 20, p 4683 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:20, p 4683 https://doi.org/10.3390/jcm10204683 kostenfrei https://doaj.org/article/7863746a7370491ba304619fc1dc32d2 kostenfrei https://www.mdpi.com/2077-0383/10/20/4683 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 20, p 4683
spelling	10.3390/jcm10204683 doi (DE-627)DOAJ077683609 (DE-599)DOAJ7863746a7370491ba304619fc1dc32d2 DE-627 ger DE-627 rakwb eng Michał Jan Stasiowski verfasserin aut Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room. surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field Medicine R Izabela Szumera verfasserin aut Piotr Wardas verfasserin aut Seweryn Król verfasserin aut Jakub Żak verfasserin aut Anna Missir verfasserin aut Aleksandra Pluta verfasserin aut Ewa Niewiadomska verfasserin aut Lech Krawczyk verfasserin aut Przemysław Jałowiecki verfasserin aut Beniamin Oskar Grabarek verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 20, p 4683 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:20, p 4683 https://doi.org/10.3390/jcm10204683 kostenfrei https://doaj.org/article/7863746a7370491ba304619fc1dc32d2 kostenfrei https://www.mdpi.com/2077-0383/10/20/4683 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 20, p 4683
allfields_unstemmed	10.3390/jcm10204683 doi (DE-627)DOAJ077683609 (DE-599)DOAJ7863746a7370491ba304619fc1dc32d2 DE-627 ger DE-627 rakwb eng Michał Jan Stasiowski verfasserin aut Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room. surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field Medicine R Izabela Szumera verfasserin aut Piotr Wardas verfasserin aut Seweryn Król verfasserin aut Jakub Żak verfasserin aut Anna Missir verfasserin aut Aleksandra Pluta verfasserin aut Ewa Niewiadomska verfasserin aut Lech Krawczyk verfasserin aut Przemysław Jałowiecki verfasserin aut Beniamin Oskar Grabarek verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 20, p 4683 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:20, p 4683 https://doi.org/10.3390/jcm10204683 kostenfrei https://doaj.org/article/7863746a7370491ba304619fc1dc32d2 kostenfrei https://www.mdpi.com/2077-0383/10/20/4683 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 20, p 4683
allfieldsGer	10.3390/jcm10204683 doi (DE-627)DOAJ077683609 (DE-599)DOAJ7863746a7370491ba304619fc1dc32d2 DE-627 ger DE-627 rakwb eng Michał Jan Stasiowski verfasserin aut Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room. surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field Medicine R Izabela Szumera verfasserin aut Piotr Wardas verfasserin aut Seweryn Król verfasserin aut Jakub Żak verfasserin aut Anna Missir verfasserin aut Aleksandra Pluta verfasserin aut Ewa Niewiadomska verfasserin aut Lech Krawczyk verfasserin aut Przemysław Jałowiecki verfasserin aut Beniamin Oskar Grabarek verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 20, p 4683 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:20, p 4683 https://doi.org/10.3390/jcm10204683 kostenfrei https://doaj.org/article/7863746a7370491ba304619fc1dc32d2 kostenfrei https://www.mdpi.com/2077-0383/10/20/4683 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 20, p 4683
allfieldsSound	10.3390/jcm10204683 doi (DE-627)DOAJ077683609 (DE-599)DOAJ7863746a7370491ba304619fc1dc32d2 DE-627 ger DE-627 rakwb eng Michał Jan Stasiowski verfasserin aut Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room. surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field Medicine R Izabela Szumera verfasserin aut Piotr Wardas verfasserin aut Seweryn Król verfasserin aut Jakub Żak verfasserin aut Anna Missir verfasserin aut Aleksandra Pluta verfasserin aut Ewa Niewiadomska verfasserin aut Lech Krawczyk verfasserin aut Przemysław Jałowiecki verfasserin aut Beniamin Oskar Grabarek verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 10(2021), 20, p 4683 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:10 year:2021 number:20, p 4683 https://doi.org/10.3390/jcm10204683 kostenfrei https://doaj.org/article/7863746a7370491ba304619fc1dc32d2 kostenfrei https://www.mdpi.com/2077-0383/10/20/4683 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 20, p 4683
language	English
source	In Journal of Clinical Medicine 10(2021), 20, p 4683 volume:10 year:2021 number:20, p 4683
sourceStr	In Journal of Clinical Medicine 10(2021), 20, p 4683 volume:10 year:2021 number:20, p 4683
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field Medicine R
isfreeaccess_bool	true
container_title	Journal of Clinical Medicine
authorswithroles_txt_mv	Michał Jan Stasiowski @@aut@@ Izabela Szumera @@aut@@ Piotr Wardas @@aut@@ Seweryn Król @@aut@@ Jakub Żak @@aut@@ Anna Missir @@aut@@ Aleksandra Pluta @@aut@@ Ewa Niewiadomska @@aut@@ Lech Krawczyk @@aut@@ Przemysław Jałowiecki @@aut@@ Beniamin Oskar Grabarek @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
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author	Michał Jan Stasiowski
spellingShingle	Michał Jan Stasiowski misc surgical pleth index misc pupillary dilatation reflex misc endoscopic sinus surgery misc Boezaart bleeding scale misc total estimated intraoperative blood loss misc condition of the surgical field misc Medicine misc R Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery
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topic_title	Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery surgical pleth index pupillary dilatation reflex endoscopic sinus surgery Boezaart bleeding scale total estimated intraoperative blood loss condition of the surgical field
topic	misc surgical pleth index misc pupillary dilatation reflex misc endoscopic sinus surgery misc Boezaart bleeding scale misc total estimated intraoperative blood loss misc condition of the surgical field misc Medicine misc R
topic_unstemmed	misc surgical pleth index misc pupillary dilatation reflex misc endoscopic sinus surgery misc Boezaart bleeding scale misc total estimated intraoperative blood loss misc condition of the surgical field misc Medicine misc R
topic_browse	misc surgical pleth index misc pupillary dilatation reflex misc endoscopic sinus surgery misc Boezaart bleeding scale misc total estimated intraoperative blood loss misc condition of the surgical field misc Medicine misc R
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title	Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery
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title_full	Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery
author_sort	Michał Jan Stasiowski
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author_browse	Michał Jan Stasiowski Izabela Szumera Piotr Wardas Seweryn Król Jakub Żak Anna Missir Aleksandra Pluta Ewa Niewiadomska Lech Krawczyk Przemysław Jałowiecki Beniamin Oskar Grabarek
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title_sort	adequacy of anesthesia and pupillometry for endoscopic sinus surgery
title_auth	Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery
abstract	Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room.
abstractGer	Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room.
abstract_unstemmed	Inadequate intraoperative analgesia causes the deterioration of the condition of the surgical field (CSF) as a result of hemodynamic instability. Analgesia monitors are used to guide remifentanil) infusion to optimize intraoperative analgesia. The main aim of the current randomized controlled trial was to investigate the potential advantages of intraoperative analgesia monitoring using surgical Pleth index (SPI)- or pupillometry (PRD)-guided remifentanil administration for managing the volume of total intraoperative blood loss (TEIBL), CSF, and length of operation (LOP) in comparison with the standard practice in patients undergoing endoscopic sinus surgery (ESS). The 89 patients in our study were grouped as follows: 30 patients were assigned to the general analgesia (GA) group, 31 patients were assigned to the SPI group, and 28 patients were assigned to the PRD group. The speed of remifentanil infusion was accelerated by 50% when SPI, PRD, or BSS were increased by <15 points, <5%, or <2, respectively, in adjacent groups until their normalization. The SPI group showed significantly lower TEIBL in comparison to the GA group (165.2 ± 100.2 vs. 283.3 ± 193.5 mL; <i<p</i< < 0.05) and a higher mean arterial pressure (MAP; 73.9 ± 8 vs. 69.2 ± 6.8 mmHg; <i<p</i< < 0.05). In the PRD group, a shorter LOP compared with the GA group was observed (63.1 ± 26.7 min vs. 82.6 ± 33.1 min; <i<p</i< < 0.05). It was noted that the PRD group had a lower total remifentanil consumption than the SPI group (1.3 ± 1.4 vs. 1.8 ± 0.9 mg; <i<p</i< < 0.05). In ASA I-III patients undergoing ESS, intraoperative monitoring based on state entropy and SPI values can optimize the CSF and reduce TEIBL, whereas monitoring based on state entropy and PRD measurements can optimize the cost effectiveness of anesthetic drugs and the use of the operation room.
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title_short	Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery
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Adequacy of Anesthesia and Pupillometry for Endoscopic Sinus Surgery

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