Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival

Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investiga...
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Autor*in:	Takaya Yamamoto [verfasserIn] Yuzuru Niibe [verfasserIn] Masahiko Aoki [verfasserIn] Takashi Shintani [verfasserIn] Kazunari Yamada [verfasserIn] Mitsuru Kobayashi [verfasserIn] Hideomi Yamashita [verfasserIn] Masatoki Ozaki [verfasserIn] Yoshihiko Manabe [verfasserIn] Hiroshi Onishi [verfasserIn] Katsuya Yahara [verfasserIn] Atsushi Nishikawa [verfasserIn] Kuniaki Katsui [verfasserIn] Ryoong-Jin Oh [verfasserIn] Atsuro Terahara [verfasserIn] Keiichi Jingu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy

Übergeordnetes Werk:	In: BMC Cancer - BMC, 2003, 20(2020), 1, Seite 10
Übergeordnetes Werk:	volume:20 ; year:2020 ; number:1 ; pages:10

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/s12885-020-07514-9

Katalog-ID:	DOAJ077870891

Internformat


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245	1	0	\|a Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
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520			\|a Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure.
650		4	\|a Pulmonary oligometastases
650		4	\|a Oligo-recurrence
650		4	\|a Sync-oligometastases
650		4	\|a Stereotactic body radiotherapy
650		4	\|a Local control
650		4	\|a Metastasis-directed therapy
653		0	\|a Neoplasms. Tumors. Oncology. Including cancer and carcinogens
700	0		\|a Yuzuru Niibe \|e verfasserin \|4 aut
700	0		\|a Masahiko Aoki \|e verfasserin \|4 aut
700	0		\|a Takashi Shintani \|e verfasserin \|4 aut
700	0		\|a Kazunari Yamada \|e verfasserin \|4 aut
700	0		\|a Mitsuru Kobayashi \|e verfasserin \|4 aut
700	0		\|a Hideomi Yamashita \|e verfasserin \|4 aut
700	0		\|a Masatoki Ozaki \|e verfasserin \|4 aut
700	0		\|a Yoshihiko Manabe \|e verfasserin \|4 aut
700	0		\|a Hiroshi Onishi \|e verfasserin \|4 aut
700	0		\|a Katsuya Yahara \|e verfasserin \|4 aut
700	0		\|a Atsushi Nishikawa \|e verfasserin \|4 aut
700	0		\|a Kuniaki Katsui \|e verfasserin \|4 aut
700	0		\|a Ryoong-Jin Oh \|e verfasserin \|4 aut
700	0		\|a Atsuro Terahara \|e verfasserin \|4 aut
700	0		\|a Keiichi Jingu \|e verfasserin \|4 aut
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allfields	10.1186/s12885-020-07514-9 doi (DE-627)DOAJ077870891 (DE-599)DOAJ5ec43898173343a1956fe60ec1b18540 DE-627 ger DE-627 rakwb eng RC254-282 Takaya Yamamoto verfasserin aut Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure. Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yuzuru Niibe verfasserin aut Masahiko Aoki verfasserin aut Takashi Shintani verfasserin aut Kazunari Yamada verfasserin aut Mitsuru Kobayashi verfasserin aut Hideomi Yamashita verfasserin aut Masatoki Ozaki verfasserin aut Yoshihiko Manabe verfasserin aut Hiroshi Onishi verfasserin aut Katsuya Yahara verfasserin aut Atsushi Nishikawa verfasserin aut Kuniaki Katsui verfasserin aut Ryoong-Jin Oh verfasserin aut Atsuro Terahara verfasserin aut Keiichi Jingu verfasserin aut In BMC Cancer BMC, 2003 20(2020), 1, Seite 10 (DE-627)326643710 (DE-600)2041352-X 14712407 nnns volume:20 year:2020 number:1 pages:10 https://doi.org/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/article/5ec43898173343a1956fe60ec1b18540 kostenfrei http://link.springer.com/article/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/toc/1471-2407 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2020 1 10
spelling	10.1186/s12885-020-07514-9 doi (DE-627)DOAJ077870891 (DE-599)DOAJ5ec43898173343a1956fe60ec1b18540 DE-627 ger DE-627 rakwb eng RC254-282 Takaya Yamamoto verfasserin aut Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure. Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yuzuru Niibe verfasserin aut Masahiko Aoki verfasserin aut Takashi Shintani verfasserin aut Kazunari Yamada verfasserin aut Mitsuru Kobayashi verfasserin aut Hideomi Yamashita verfasserin aut Masatoki Ozaki verfasserin aut Yoshihiko Manabe verfasserin aut Hiroshi Onishi verfasserin aut Katsuya Yahara verfasserin aut Atsushi Nishikawa verfasserin aut Kuniaki Katsui verfasserin aut Ryoong-Jin Oh verfasserin aut Atsuro Terahara verfasserin aut Keiichi Jingu verfasserin aut In BMC Cancer BMC, 2003 20(2020), 1, Seite 10 (DE-627)326643710 (DE-600)2041352-X 14712407 nnns volume:20 year:2020 number:1 pages:10 https://doi.org/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/article/5ec43898173343a1956fe60ec1b18540 kostenfrei http://link.springer.com/article/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/toc/1471-2407 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2020 1 10
allfields_unstemmed	10.1186/s12885-020-07514-9 doi (DE-627)DOAJ077870891 (DE-599)DOAJ5ec43898173343a1956fe60ec1b18540 DE-627 ger DE-627 rakwb eng RC254-282 Takaya Yamamoto verfasserin aut Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure. Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yuzuru Niibe verfasserin aut Masahiko Aoki verfasserin aut Takashi Shintani verfasserin aut Kazunari Yamada verfasserin aut Mitsuru Kobayashi verfasserin aut Hideomi Yamashita verfasserin aut Masatoki Ozaki verfasserin aut Yoshihiko Manabe verfasserin aut Hiroshi Onishi verfasserin aut Katsuya Yahara verfasserin aut Atsushi Nishikawa verfasserin aut Kuniaki Katsui verfasserin aut Ryoong-Jin Oh verfasserin aut Atsuro Terahara verfasserin aut Keiichi Jingu verfasserin aut In BMC Cancer BMC, 2003 20(2020), 1, Seite 10 (DE-627)326643710 (DE-600)2041352-X 14712407 nnns volume:20 year:2020 number:1 pages:10 https://doi.org/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/article/5ec43898173343a1956fe60ec1b18540 kostenfrei http://link.springer.com/article/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/toc/1471-2407 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2020 1 10
allfieldsGer	10.1186/s12885-020-07514-9 doi (DE-627)DOAJ077870891 (DE-599)DOAJ5ec43898173343a1956fe60ec1b18540 DE-627 ger DE-627 rakwb eng RC254-282 Takaya Yamamoto verfasserin aut Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure. Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yuzuru Niibe verfasserin aut Masahiko Aoki verfasserin aut Takashi Shintani verfasserin aut Kazunari Yamada verfasserin aut Mitsuru Kobayashi verfasserin aut Hideomi Yamashita verfasserin aut Masatoki Ozaki verfasserin aut Yoshihiko Manabe verfasserin aut Hiroshi Onishi verfasserin aut Katsuya Yahara verfasserin aut Atsushi Nishikawa verfasserin aut Kuniaki Katsui verfasserin aut Ryoong-Jin Oh verfasserin aut Atsuro Terahara verfasserin aut Keiichi Jingu verfasserin aut In BMC Cancer BMC, 2003 20(2020), 1, Seite 10 (DE-627)326643710 (DE-600)2041352-X 14712407 nnns volume:20 year:2020 number:1 pages:10 https://doi.org/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/article/5ec43898173343a1956fe60ec1b18540 kostenfrei http://link.springer.com/article/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/toc/1471-2407 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2020 1 10
allfieldsSound	10.1186/s12885-020-07514-9 doi (DE-627)DOAJ077870891 (DE-599)DOAJ5ec43898173343a1956fe60ec1b18540 DE-627 ger DE-627 rakwb eng RC254-282 Takaya Yamamoto verfasserin aut Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure. Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yuzuru Niibe verfasserin aut Masahiko Aoki verfasserin aut Takashi Shintani verfasserin aut Kazunari Yamada verfasserin aut Mitsuru Kobayashi verfasserin aut Hideomi Yamashita verfasserin aut Masatoki Ozaki verfasserin aut Yoshihiko Manabe verfasserin aut Hiroshi Onishi verfasserin aut Katsuya Yahara verfasserin aut Atsushi Nishikawa verfasserin aut Kuniaki Katsui verfasserin aut Ryoong-Jin Oh verfasserin aut Atsuro Terahara verfasserin aut Keiichi Jingu verfasserin aut In BMC Cancer BMC, 2003 20(2020), 1, Seite 10 (DE-627)326643710 (DE-600)2041352-X 14712407 nnns volume:20 year:2020 number:1 pages:10 https://doi.org/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/article/5ec43898173343a1956fe60ec1b18540 kostenfrei http://link.springer.com/article/10.1186/s12885-020-07514-9 kostenfrei https://doaj.org/toc/1471-2407 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2020 1 10
language	English
source	In BMC Cancer 20(2020), 1, Seite 10 volume:20 year:2020 number:1 pages:10
sourceStr	In BMC Cancer 20(2020), 1, Seite 10 volume:20 year:2020 number:1 pages:10
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens
isfreeaccess_bool	true
container_title	BMC Cancer
authorswithroles_txt_mv	Takaya Yamamoto @@aut@@ Yuzuru Niibe @@aut@@ Masahiko Aoki @@aut@@ Takashi Shintani @@aut@@ Kazunari Yamada @@aut@@ Mitsuru Kobayashi @@aut@@ Hideomi Yamashita @@aut@@ Masatoki Ozaki @@aut@@ Yoshihiko Manabe @@aut@@ Hiroshi Onishi @@aut@@ Katsuya Yahara @@aut@@ Atsushi Nishikawa @@aut@@ Kuniaki Katsui @@aut@@ Ryoong-Jin Oh @@aut@@ Atsuro Terahara @@aut@@ Keiichi Jingu @@aut@@
publishDateDaySort_date	2020-01-01T00:00:00Z
hierarchy_top_id	326643710
id	DOAJ077870891
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ077870891</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230502130614.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2020 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1186/s12885-020-07514-9</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ077870891</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ5ec43898173343a1956fe60ec1b18540</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC254-282</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Takaya Yamamoto</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. 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callnumber-first	R - Medicine
author	Takaya Yamamoto
spellingShingle	Takaya Yamamoto misc RC254-282 misc Pulmonary oligometastases misc Oligo-recurrence misc Sync-oligometastases misc Stereotactic body radiotherapy misc Local control misc Metastasis-directed therapy misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
authorStr	Takaya Yamamoto
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topic_title	RC254-282 Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival Pulmonary oligometastases Oligo-recurrence Sync-oligometastases Stereotactic body radiotherapy Local control Metastasis-directed therapy
topic	misc RC254-282 misc Pulmonary oligometastases misc Oligo-recurrence misc Sync-oligometastases misc Stereotactic body radiotherapy misc Local control misc Metastasis-directed therapy misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RC254-282 misc Pulmonary oligometastases misc Oligo-recurrence misc Sync-oligometastases misc Stereotactic body radiotherapy misc Local control misc Metastasis-directed therapy misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_browse	misc RC254-282 misc Pulmonary oligometastases misc Oligo-recurrence misc Sync-oligometastases misc Stereotactic body radiotherapy misc Local control misc Metastasis-directed therapy misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
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title_full	Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
author_sort	Takaya Yamamoto
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author_browse	Takaya Yamamoto Yuzuru Niibe Masahiko Aoki Takashi Shintani Kazunari Yamada Mitsuru Kobayashi Hideomi Yamashita Masatoki Ozaki Yoshihiko Manabe Hiroshi Onishi Katsuya Yahara Atsushi Nishikawa Kuniaki Katsui Ryoong-Jin Oh Atsuro Terahara Keiichi Jingu
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title_sort	analyses of the local control of pulmonary oligometastases after stereotactic body radiotherapy and the impact of local control on survival
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title_auth	Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
abstract	Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure.
abstractGer	Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure.
abstract_unstemmed	Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure.
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title_short	Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival
url	https://doi.org/10.1186/s12885-020-07514-9 https://doaj.org/article/5ec43898173343a1956fe60ec1b18540 http://link.springer.com/article/10.1186/s12885-020-07514-9 https://doaj.org/toc/1471-2407
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up_date	2024-07-03T14:38:15.663Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ077870891</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230502130614.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230228s2020 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1186/s12885-020-07514-9</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ077870891</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ5ec43898173343a1956fe60ec1b18540</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC254-282</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Takaya Yamamoto</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Background Successful local therapy for oligometastases may lead to longer survival. The purpose of this multicentre retrospective study was to investigate factors affecting the local control (LC) of pulmonary oligometastases treated by stereotactic body radiotherapy (SBRT) and to investigate the impact of LC on survival. Methods The inclusion criteria included 1 to 5 metastases, the primary lesion and other extrathoracic metastases were controlled before SBRT, and the biological effective dose (BED10) of the SBRT was 75 Gy or more. The Cox proportional hazards model was used for analyses. Results Data of 1378 patients with 1547 tumours from 68 institutions were analysed. The median follow-up period was 24.2 months. The one-year, 3-year and 5-year LC rates were 92.1, 81.3 and 78.6%, respectively, and the 1-year, 3-year and 5-year overall survival rates were 90.1, 60.3 and 45.5%, respectively. Multivariate analysis for LC showed that increased maximum tumour diameter (p = 0.011), type A dose calculation algorithm (p = 0.005), shorter overall treatment time of SBRT (p = 0.035) and colorectal primary origin (p < 0.001 excluding oesophagus origin) were significantly associated with a lower LC rate. In the survival analysis, local failure (p < 0.001), worse performance status (1 vs. 0, p = 0.013; 2–3 vs. 0, p < 0.001), oesophageal primary origin (vs. colorectal origin, p = 0.038), squamous cell carcinoma (vs. adenocarcinoma, p = 0.006) and increased maximum tumour diameter (p < 0.001) showed significant relationships with shorter survival. Conclusions Several factors of oligometastases and SBRT affected LC. LC of pulmonary oligometastases by SBRT showed a significant survival benefit compared to patients with local failure.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pulmonary oligometastases</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Oligo-recurrence</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sync-oligometastases</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Stereotactic body radiotherapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Local control</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Metastasis-directed therapy</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neoplasms. Tumors. Oncology. Including cancer and carcinogens</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yuzuru Niibe</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Masahiko Aoki</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Takashi Shintani</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kazunari Yamada</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mitsuru Kobayashi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hideomi Yamashita</subfield><subfield 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Analyses of the local control of pulmonary Oligometastases after stereotactic body radiotherapy and the impact of local control on survival

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