Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma

Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwe...
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Autor*in:	Jong Heon Lim [verfasserIn] Dong Wook Kim [verfasserIn] Jin Young Park [verfasserIn] Yoo Jin Lee [verfasserIn] Ha Kyoung Park [verfasserIn] Tae Kwun Ha [verfasserIn] Do Hun Kim [verfasserIn] Soo Jin Jung [verfasserIn] Ji Sun Park [verfasserIn] Sung Ho Moon [verfasserIn] Ki Jung Ahn [verfasserIn] Hye Jin Baek [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin

Übergeordnetes Werk:	In: Frontiers in Endocrinology - Frontiers Media S.A., 2011, 10(2019)
Übergeordnetes Werk:	volume:10 ; year:2019

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fendo.2019.00395

Katalog-ID:	DOAJ078427983

Internformat


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245	1	0	\|a Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma
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520			\|a Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC.
650		4	\|a papillary thyroid carcinoma
650		4	\|a lymph node
650		4	\|a metastasis
650		4	\|a ultrasonography
650		4	\|a fine-needle aspiration
650		4	\|a thyroglobulin
653		0	\|a Diseases of the endocrine glands. Clinical endocrinology
700	0		\|a Dong Wook Kim \|e verfasserin \|4 aut
700	0		\|a Jin Young Park \|e verfasserin \|4 aut
700	0		\|a Yoo Jin Lee \|e verfasserin \|4 aut
700	0		\|a Ha Kyoung Park \|e verfasserin \|4 aut
700	0		\|a Tae Kwun Ha \|e verfasserin \|4 aut
700	0		\|a Do Hun Kim \|e verfasserin \|4 aut
700	0		\|a Soo Jin Jung \|e verfasserin \|4 aut
700	0		\|a Ji Sun Park \|e verfasserin \|4 aut
700	0		\|a Sung Ho Moon \|e verfasserin \|4 aut
700	0		\|a Ki Jung Ahn \|e verfasserin \|4 aut
700	0		\|a Hye Jin Baek \|e verfasserin \|4 aut
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allfields	10.3389/fendo.2019.00395 doi (DE-627)DOAJ078427983 (DE-599)DOAJ4d8df347b5104dda9e9b32213477ea8a DE-627 ger DE-627 rakwb eng RC648-665 Jong Heon Lim verfasserin aut Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC. papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin Diseases of the endocrine glands. Clinical endocrinology Dong Wook Kim verfasserin aut Jin Young Park verfasserin aut Yoo Jin Lee verfasserin aut Ha Kyoung Park verfasserin aut Tae Kwun Ha verfasserin aut Do Hun Kim verfasserin aut Soo Jin Jung verfasserin aut Ji Sun Park verfasserin aut Sung Ho Moon verfasserin aut Ki Jung Ahn verfasserin aut Hye Jin Baek verfasserin aut In Frontiers in Endocrinology Frontiers Media S.A., 2011 10(2019) (DE-627)645090948 (DE-600)2592084-4 16642392 nnns volume:10 year:2019 https://doi.org/10.3389/fendo.2019.00395 kostenfrei https://doaj.org/article/4d8df347b5104dda9e9b32213477ea8a kostenfrei https://www.frontiersin.org/article/10.3389/fendo.2019.00395/full kostenfrei https://doaj.org/toc/1664-2392 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019
spelling	10.3389/fendo.2019.00395 doi (DE-627)DOAJ078427983 (DE-599)DOAJ4d8df347b5104dda9e9b32213477ea8a DE-627 ger DE-627 rakwb eng RC648-665 Jong Heon Lim verfasserin aut Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC. papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin Diseases of the endocrine glands. Clinical endocrinology Dong Wook Kim verfasserin aut Jin Young Park verfasserin aut Yoo Jin Lee verfasserin aut Ha Kyoung Park verfasserin aut Tae Kwun Ha verfasserin aut Do Hun Kim verfasserin aut Soo Jin Jung verfasserin aut Ji Sun Park verfasserin aut Sung Ho Moon verfasserin aut Ki Jung Ahn verfasserin aut Hye Jin Baek verfasserin aut In Frontiers in Endocrinology Frontiers Media S.A., 2011 10(2019) (DE-627)645090948 (DE-600)2592084-4 16642392 nnns volume:10 year:2019 https://doi.org/10.3389/fendo.2019.00395 kostenfrei https://doaj.org/article/4d8df347b5104dda9e9b32213477ea8a kostenfrei https://www.frontiersin.org/article/10.3389/fendo.2019.00395/full kostenfrei https://doaj.org/toc/1664-2392 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019
allfields_unstemmed	10.3389/fendo.2019.00395 doi (DE-627)DOAJ078427983 (DE-599)DOAJ4d8df347b5104dda9e9b32213477ea8a DE-627 ger DE-627 rakwb eng RC648-665 Jong Heon Lim verfasserin aut Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC. papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin Diseases of the endocrine glands. Clinical endocrinology Dong Wook Kim verfasserin aut Jin Young Park verfasserin aut Yoo Jin Lee verfasserin aut Ha Kyoung Park verfasserin aut Tae Kwun Ha verfasserin aut Do Hun Kim verfasserin aut Soo Jin Jung verfasserin aut Ji Sun Park verfasserin aut Sung Ho Moon verfasserin aut Ki Jung Ahn verfasserin aut Hye Jin Baek verfasserin aut In Frontiers in Endocrinology Frontiers Media S.A., 2011 10(2019) (DE-627)645090948 (DE-600)2592084-4 16642392 nnns volume:10 year:2019 https://doi.org/10.3389/fendo.2019.00395 kostenfrei https://doaj.org/article/4d8df347b5104dda9e9b32213477ea8a kostenfrei https://www.frontiersin.org/article/10.3389/fendo.2019.00395/full kostenfrei https://doaj.org/toc/1664-2392 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019
allfieldsGer	10.3389/fendo.2019.00395 doi (DE-627)DOAJ078427983 (DE-599)DOAJ4d8df347b5104dda9e9b32213477ea8a DE-627 ger DE-627 rakwb eng RC648-665 Jong Heon Lim verfasserin aut Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC. papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin Diseases of the endocrine glands. Clinical endocrinology Dong Wook Kim verfasserin aut Jin Young Park verfasserin aut Yoo Jin Lee verfasserin aut Ha Kyoung Park verfasserin aut Tae Kwun Ha verfasserin aut Do Hun Kim verfasserin aut Soo Jin Jung verfasserin aut Ji Sun Park verfasserin aut Sung Ho Moon verfasserin aut Ki Jung Ahn verfasserin aut Hye Jin Baek verfasserin aut In Frontiers in Endocrinology Frontiers Media S.A., 2011 10(2019) (DE-627)645090948 (DE-600)2592084-4 16642392 nnns volume:10 year:2019 https://doi.org/10.3389/fendo.2019.00395 kostenfrei https://doaj.org/article/4d8df347b5104dda9e9b32213477ea8a kostenfrei https://www.frontiersin.org/article/10.3389/fendo.2019.00395/full kostenfrei https://doaj.org/toc/1664-2392 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019
allfieldsSound	10.3389/fendo.2019.00395 doi (DE-627)DOAJ078427983 (DE-599)DOAJ4d8df347b5104dda9e9b32213477ea8a DE-627 ger DE-627 rakwb eng RC648-665 Jong Heon Lim verfasserin aut Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC. papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin Diseases of the endocrine glands. Clinical endocrinology Dong Wook Kim verfasserin aut Jin Young Park verfasserin aut Yoo Jin Lee verfasserin aut Ha Kyoung Park verfasserin aut Tae Kwun Ha verfasserin aut Do Hun Kim verfasserin aut Soo Jin Jung verfasserin aut Ji Sun Park verfasserin aut Sung Ho Moon verfasserin aut Ki Jung Ahn verfasserin aut Hye Jin Baek verfasserin aut In Frontiers in Endocrinology Frontiers Media S.A., 2011 10(2019) (DE-627)645090948 (DE-600)2592084-4 16642392 nnns volume:10 year:2019 https://doi.org/10.3389/fendo.2019.00395 kostenfrei https://doaj.org/article/4d8df347b5104dda9e9b32213477ea8a kostenfrei https://www.frontiersin.org/article/10.3389/fendo.2019.00395/full kostenfrei https://doaj.org/toc/1664-2392 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019
language	English
source	In Frontiers in Endocrinology 10(2019) volume:10 year:2019
sourceStr	In Frontiers in Endocrinology 10(2019) volume:10 year:2019
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin Diseases of the endocrine glands. Clinical endocrinology
isfreeaccess_bool	true
container_title	Frontiers in Endocrinology
authorswithroles_txt_mv	Jong Heon Lim @@aut@@ Dong Wook Kim @@aut@@ Jin Young Park @@aut@@ Yoo Jin Lee @@aut@@ Ha Kyoung Park @@aut@@ Tae Kwun Ha @@aut@@ Do Hun Kim @@aut@@ Soo Jin Jung @@aut@@ Ji Sun Park @@aut@@ Sung Ho Moon @@aut@@ Ki Jung Ahn @@aut@@ Hye Jin Baek @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
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id	DOAJ078427983
language_de	englisch
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author	Jong Heon Lim
spellingShingle	Jong Heon Lim misc RC648-665 misc papillary thyroid carcinoma misc lymph node misc metastasis misc ultrasonography misc fine-needle aspiration misc thyroglobulin misc Diseases of the endocrine glands. Clinical endocrinology Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma
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topic_title	RC648-665 Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma papillary thyroid carcinoma lymph node metastasis ultrasonography fine-needle aspiration thyroglobulin
topic	misc RC648-665 misc papillary thyroid carcinoma misc lymph node misc metastasis misc ultrasonography misc fine-needle aspiration misc thyroglobulin misc Diseases of the endocrine glands. Clinical endocrinology
topic_unstemmed	misc RC648-665 misc papillary thyroid carcinoma misc lymph node misc metastasis misc ultrasonography misc fine-needle aspiration misc thyroglobulin misc Diseases of the endocrine glands. Clinical endocrinology
topic_browse	misc RC648-665 misc papillary thyroid carcinoma misc lymph node misc metastasis misc ultrasonography misc fine-needle aspiration misc thyroglobulin misc Diseases of the endocrine glands. Clinical endocrinology
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title	Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma
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title_full	Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma
author_sort	Jong Heon Lim
journal	Frontiers in Endocrinology
journalStr	Frontiers in Endocrinology
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author_browse	Jong Heon Lim Dong Wook Kim Jin Young Park Yoo Jin Lee Ha Kyoung Park Tae Kwun Ha Do Hun Kim Soo Jin Jung Ji Sun Park Sung Ho Moon Ki Jung Ahn Hye Jin Baek
container_volume	10
class	RC648-665
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author-letter	Jong Heon Lim
doi_str_mv	10.3389/fendo.2019.00395
author2-role	verfasserin
title_sort	ultrasonography, cytology, and thyroglobulin measurement results of cervical nodal metastasis in patients with unclear papillary thyroid carcinoma
callnumber	RC648-665
title_auth	Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma
abstract	Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC.
abstractGer	Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC.
abstract_unstemmed	Objective: This study aimed to evaluate the ultrasonography (US), cytology, and thyroglobulin (Tg) measurement results of nodal metastasis in patients showing unclear US or cytology results of primary papillary thyroid carcinoma (PTC).Methods: From January 2016 to December 2018, 179 patients underwent US-guided fine-needle aspiration (FNA) to diagnose lymphadenopathy in the neck. Among them, 36 patients underwent subsequent total thyroidectomy and nodal dissection, and cervical lymph node (LN) metastasis from PTC was confirmed. However, two patients were excluded because of mismatch between the US and pathological findings of LNs. US images and cytological slides for metastatic LNs were retrospectively analyzed, and serum and FNA Tg levels for metastatic LNs were investigated using data from the electric medical records. Primary PTC patients with suspicious results on both US and cytology were classified as the clear group, and the remaining patients were classified as the unclear group.Results: Of the 34 patients, 24 had clear results of primary PTC on both US and cytology (clear group), whereas 10 had unclear results of primary PTC on US or cytology (unclear group). Of the 10 patients in the unclear group, seven had suspicious nodal metastasis from PTC on cytology after US-guided FNA of the cervical LN, and the remaining three had negative cytology but a positive Tg measurement. Metastatic LNs with cystic change tended to show a positive Tg measurement but negative cytology.Conclusions: The combination of US, cytology, and Tg measurement is necessary for diagnosing nodal metastasis from PTC. In cases with unclear primary PTC on US or cytology, the detection of nodal metastasis may be helpful for assessing primary PTC.
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title_short	Ultrasonography, Cytology, and Thyroglobulin Measurement Results of Cervical Nodal Metastasis in Patients With Unclear Papillary Thyroid Carcinoma
url	https://doi.org/10.3389/fendo.2019.00395 https://doaj.org/article/4d8df347b5104dda9e9b32213477ea8a https://www.frontiersin.org/article/10.3389/fendo.2019.00395/full https://doaj.org/toc/1664-2392
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author2	Dong Wook Kim Jin Young Park Yoo Jin Lee Ha Kyoung Park Tae Kwun Ha Do Hun Kim Soo Jin Jung Ji Sun Park Sung Ho Moon Ki Jung Ahn Hye Jin Baek
author2Str	Dong Wook Kim Jin Young Park Yoo Jin Lee Ha Kyoung Park Tae Kwun Ha Do Hun Kim Soo Jin Jung Ji Sun Park Sung Ho Moon Ki Jung Ahn Hye Jin Baek
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doi_str	10.3389/fendo.2019.00395
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up_date	2024-07-03T17:54:57.847Z
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