DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS

Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood c...
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Autor*in:	T. N. Rybalkina [verfasserIn] N. V. Karazhas [verfasserIn] P. A. Savinkov [verfasserIn] R. E. Boshyan [verfasserIn] M. Yu. Lysenkova [verfasserIn] M. N. Kornienko [verfasserIn] E. M. Burmistrov [verfasserIn] P. A. Veselovsky [verfasserIn] I. A. Soldatova [verfasserIn]

Format:	E-Artikel
Sprache:	Russisch

Erschienen:	2018

Schlagwörter:	hiv infection opportunistic infections herpesvirus infections pneumocystis active infection markers latent infection

Übergeordnetes Werk:	In: Журнал микробиологии, эпидемиологии и иммунобиологии - Central Research Institute for Epidemiology, 2020, (2018), 4, Seite 76-81
Übergeordnetes Werk:	year:2018 ; number:4 ; pages:76-81

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.36233/0372-9311-2018-4-76-81

Katalog-ID:	DOAJ078857171

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allfields	10.36233/0372-9311-2018-4-76-81 doi (DE-627)DOAJ078857171 (DE-599)DOAJ595c139fd46543de8f490e051863daf3 DE-627 ger DE-627 rakwb rus QR1-502 T. N. Rybalkina verfasserin aut DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment. hiv infection opportunistic infections herpesvirus infections pneumocystis active infection markers latent infection Microbiology N. V. Karazhas verfasserin aut P. A. Savinkov verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Lysenkova verfasserin aut M. N. Kornienko verfasserin aut E. M. Burmistrov verfasserin aut P. A. Veselovsky verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2018), 4, Seite 76-81 (DE-627)1760649171 26867613 nnns year:2018 number:4 pages:76-81 https://doi.org/10.36233/0372-9311-2018-4-76-81 kostenfrei https://doaj.org/article/595c139fd46543de8f490e051863daf3 kostenfrei https://microbiol.elpub.ru/jour/article/view/290 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2018 4 76-81
spelling	10.36233/0372-9311-2018-4-76-81 doi (DE-627)DOAJ078857171 (DE-599)DOAJ595c139fd46543de8f490e051863daf3 DE-627 ger DE-627 rakwb rus QR1-502 T. N. Rybalkina verfasserin aut DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment. hiv infection opportunistic infections herpesvirus infections pneumocystis active infection markers latent infection Microbiology N. V. Karazhas verfasserin aut P. A. Savinkov verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Lysenkova verfasserin aut M. N. Kornienko verfasserin aut E. M. Burmistrov verfasserin aut P. A. Veselovsky verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2018), 4, Seite 76-81 (DE-627)1760649171 26867613 nnns year:2018 number:4 pages:76-81 https://doi.org/10.36233/0372-9311-2018-4-76-81 kostenfrei https://doaj.org/article/595c139fd46543de8f490e051863daf3 kostenfrei https://microbiol.elpub.ru/jour/article/view/290 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2018 4 76-81
allfields_unstemmed	10.36233/0372-9311-2018-4-76-81 doi (DE-627)DOAJ078857171 (DE-599)DOAJ595c139fd46543de8f490e051863daf3 DE-627 ger DE-627 rakwb rus QR1-502 T. N. Rybalkina verfasserin aut DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment. hiv infection opportunistic infections herpesvirus infections pneumocystis active infection markers latent infection Microbiology N. V. Karazhas verfasserin aut P. A. Savinkov verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Lysenkova verfasserin aut M. N. Kornienko verfasserin aut E. M. Burmistrov verfasserin aut P. A. Veselovsky verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2018), 4, Seite 76-81 (DE-627)1760649171 26867613 nnns year:2018 number:4 pages:76-81 https://doi.org/10.36233/0372-9311-2018-4-76-81 kostenfrei https://doaj.org/article/595c139fd46543de8f490e051863daf3 kostenfrei https://microbiol.elpub.ru/jour/article/view/290 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2018 4 76-81
allfieldsGer	10.36233/0372-9311-2018-4-76-81 doi (DE-627)DOAJ078857171 (DE-599)DOAJ595c139fd46543de8f490e051863daf3 DE-627 ger DE-627 rakwb rus QR1-502 T. N. Rybalkina verfasserin aut DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment. hiv infection opportunistic infections herpesvirus infections pneumocystis active infection markers latent infection Microbiology N. V. Karazhas verfasserin aut P. A. Savinkov verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Lysenkova verfasserin aut M. N. Kornienko verfasserin aut E. M. Burmistrov verfasserin aut P. A. Veselovsky verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2018), 4, Seite 76-81 (DE-627)1760649171 26867613 nnns year:2018 number:4 pages:76-81 https://doi.org/10.36233/0372-9311-2018-4-76-81 kostenfrei https://doaj.org/article/595c139fd46543de8f490e051863daf3 kostenfrei https://microbiol.elpub.ru/jour/article/view/290 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2018 4 76-81
allfieldsSound	10.36233/0372-9311-2018-4-76-81 doi (DE-627)DOAJ078857171 (DE-599)DOAJ595c139fd46543de8f490e051863daf3 DE-627 ger DE-627 rakwb rus QR1-502 T. N. Rybalkina verfasserin aut DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment. hiv infection opportunistic infections herpesvirus infections pneumocystis active infection markers latent infection Microbiology N. V. Karazhas verfasserin aut P. A. Savinkov verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Lysenkova verfasserin aut M. N. Kornienko verfasserin aut E. M. Burmistrov verfasserin aut P. A. Veselovsky verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2018), 4, Seite 76-81 (DE-627)1760649171 26867613 nnns year:2018 number:4 pages:76-81 https://doi.org/10.36233/0372-9311-2018-4-76-81 kostenfrei https://doaj.org/article/595c139fd46543de8f490e051863daf3 kostenfrei https://microbiol.elpub.ru/jour/article/view/290 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2018 4 76-81
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callnumber-first	Q - Science
author	T. N. Rybalkina
spellingShingle	T. N. Rybalkina misc QR1-502 misc hiv infection misc opportunistic infections misc herpesvirus infections misc pneumocystis misc active infection markers misc latent infection misc Microbiology DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS
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topic_title	QR1-502 DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS hiv infection opportunistic infections herpesvirus infections pneumocystis active infection markers latent infection
topic	misc QR1-502 misc hiv infection misc opportunistic infections misc herpesvirus infections misc pneumocystis misc active infection markers misc latent infection misc Microbiology
topic_unstemmed	misc QR1-502 misc hiv infection misc opportunistic infections misc herpesvirus infections misc pneumocystis misc active infection markers misc latent infection misc Microbiology
topic_browse	misc QR1-502 misc hiv infection misc opportunistic infections misc herpesvirus infections misc pneumocystis misc active infection markers misc latent infection misc Microbiology
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title	DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS
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title_full	DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS
author_sort	T. N. Rybalkina
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author_browse	T. N. Rybalkina N. V. Karazhas P. A. Savinkov R. E. Boshyan M. Yu. Lysenkova M. N. Kornienko E. M. Burmistrov P. A. Veselovsky I. A. Soldatova
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title_sort	dependence of detection of markers of opportunistic infections from adherence to antiretroviral therapy in children born by hiv-infected matters
callnumber	QR1-502
title_auth	DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS
abstract	Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment.
abstractGer	Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment.
abstract_unstemmed	Aim. To study the dependence of detection of markers of opportunistic infections from afherence to antiretroviral therapy in children born to HIV-infected mothers on the example of herpesvirus infectionsand pneumocystis. Materials and methods. Samples of biological materials (blood serum and blood cells) of 66 children with HIV infection aged 1 month to 15 years old were treated in Children’s Boxed Department of Children’s Hospital No. 2 with diagnoses «incomplete HIV test» (children from the age of one month to one and a half years) and «HIV infection». To determine IgM and IgG to herpesviruses and pneumocyst, the method of enzyme immunoassay was used; indirect immunofluorescence reaction for the detection of herpesviruses and their antigens in the blood, early antigens and virus reproduction were determined using a rapid culture method. Results. 56.0% of the surveyed children received complete antiretroviral therapy, in 16,7% of cases they were not complete, and 27,3% of children did not fully adhere to ARVT. Despite the fact that 100% of children with an incomplete diagnosis of HIV infection were covered by ARVT due to the use of chemotherapy drugs by their mothers during pregnancy, they still had markers of both active and latent forms of herpesvirus infections and pneumocystis. In children with confirmed HIV infection living both in social institutions and in families, the markers of opportunistic infections were more often diagnosed in patients receiving ARVT in full and not in full volume than in children who did not have it. Conclusion. Identification of markers of active forms of herpesvirus infections and pneumocystis in HIV-positive children not receiving ARV is the basis for its immediate appointment.
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title_short	DEPENDENCE OF DETECTION OF MARKERS OF OPPORTUNISTIC INFECTIONS FROM ADHERENCE TO ANTIRETROVIRAL THERAPY IN CHILDREN BORN BY HIV-INFECTED MATTERS
url	https://doi.org/10.36233/0372-9311-2018-4-76-81 https://doaj.org/article/595c139fd46543de8f490e051863daf3 https://microbiol.elpub.ru/jour/article/view/290 https://doaj.org/toc/0372-9311 https://doaj.org/toc/2686-7613
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