A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy

Globoid cell leukodystrophy (GLD), or Krabbe disease (KD) is a rare neurodegenerative disease, and adult-onset GLD is more even neglected by clinicians. This review provides detailed discussions of the serum enzymes, genes, clinical manifestations, neuroimaging features, and therapies of GLD, with p...
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Gespeichert in:

Autor*in:	Guode Wu [verfasserIn] Zhenhua Li [verfasserIn] Jing Li [verfasserIn] Xin Li [verfasserIn] Manxia Wang [verfasserIn] Jing Zhang [verfasserIn] Guangyao Liu [verfasserIn] Pengfei Zhang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	globoid cell leukodystrophy Krabbe disease adult-onset GLD galactosylceramidase GALC psychosine

Übergeordnetes Werk:	In: Frontiers in Neuroscience - Frontiers Media S.A., 2008, 16(2022)
Übergeordnetes Werk:	volume:16 ; year:2022

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fnins.2022.998275

Katalog-ID:	DOAJ078909864

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allfieldsSound	10.3389/fnins.2022.998275 doi (DE-627)DOAJ078909864 (DE-599)DOAJ688474f2cffa4330b48ae47c0fcff8b0 DE-627 ger DE-627 rakwb eng RC321-571 Guode Wu verfasserin aut A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Globoid cell leukodystrophy (GLD), or Krabbe disease (KD) is a rare neurodegenerative disease, and adult-onset GLD is more even neglected by clinicians. This review provides detailed discussions of the serum enzymes, genes, clinical manifestations, neuroimaging features, and therapies of GLD, with particular emphasis on the characteristics of adult-onset GLD, in an attempt to provide clinicians with in-depth insights into this disease. globoid cell leukodystrophy Krabbe disease adult-onset GLD galactosylceramidase GALC psychosine Neurosciences. Biological psychiatry. Neuropsychiatry Zhenhua Li verfasserin aut Jing Li verfasserin aut Xin Li verfasserin aut Manxia Wang verfasserin aut Jing Zhang verfasserin aut Guangyao Liu verfasserin aut Pengfei Zhang verfasserin aut In Frontiers in Neuroscience Frontiers Media S.A., 2008 16(2022) (DE-627)55908109X (DE-600)2411902-7 1662453X nnns volume:16 year:2022 https://doi.org/10.3389/fnins.2022.998275 kostenfrei https://doaj.org/article/688474f2cffa4330b48ae47c0fcff8b0 kostenfrei https://www.frontiersin.org/articles/10.3389/fnins.2022.998275/full kostenfrei https://doaj.org/toc/1662-453X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2022
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source	In Frontiers in Neuroscience 16(2022) volume:16 year:2022
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topic_facet	globoid cell leukodystrophy Krabbe disease adult-onset GLD galactosylceramidase GALC psychosine Neurosciences. Biological psychiatry. Neuropsychiatry
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callnumber-first	R - Medicine
author	Guode Wu
spellingShingle	Guode Wu misc RC321-571 misc globoid cell leukodystrophy misc Krabbe disease misc adult-onset GLD misc galactosylceramidase misc GALC misc psychosine misc Neurosciences. Biological psychiatry. Neuropsychiatry A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy
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topic_title	RC321-571 A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy globoid cell leukodystrophy Krabbe disease adult-onset GLD galactosylceramidase GALC psychosine
topic	misc RC321-571 misc globoid cell leukodystrophy misc Krabbe disease misc adult-onset GLD misc galactosylceramidase misc GALC misc psychosine misc Neurosciences. Biological psychiatry. Neuropsychiatry
topic_unstemmed	misc RC321-571 misc globoid cell leukodystrophy misc Krabbe disease misc adult-onset GLD misc galactosylceramidase misc GALC misc psychosine misc Neurosciences. Biological psychiatry. Neuropsychiatry
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title	A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy
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title_full	A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy
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title_sort	neglected neurodegenerative disease: adult-onset globoid cell leukodystrophy
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title_auth	A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy
abstract	Globoid cell leukodystrophy (GLD), or Krabbe disease (KD) is a rare neurodegenerative disease, and adult-onset GLD is more even neglected by clinicians. This review provides detailed discussions of the serum enzymes, genes, clinical manifestations, neuroimaging features, and therapies of GLD, with particular emphasis on the characteristics of adult-onset GLD, in an attempt to provide clinicians with in-depth insights into this disease.
abstractGer	Globoid cell leukodystrophy (GLD), or Krabbe disease (KD) is a rare neurodegenerative disease, and adult-onset GLD is more even neglected by clinicians. This review provides detailed discussions of the serum enzymes, genes, clinical manifestations, neuroimaging features, and therapies of GLD, with particular emphasis on the characteristics of adult-onset GLD, in an attempt to provide clinicians with in-depth insights into this disease.
abstract_unstemmed	Globoid cell leukodystrophy (GLD), or Krabbe disease (KD) is a rare neurodegenerative disease, and adult-onset GLD is more even neglected by clinicians. This review provides detailed discussions of the serum enzymes, genes, clinical manifestations, neuroimaging features, and therapies of GLD, with particular emphasis on the characteristics of adult-onset GLD, in an attempt to provide clinicians with in-depth insights into this disease.
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title_short	A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy
url	https://doi.org/10.3389/fnins.2022.998275 https://doaj.org/article/688474f2cffa4330b48ae47c0fcff8b0 https://www.frontiersin.org/articles/10.3389/fnins.2022.998275/full https://doaj.org/toc/1662-453X
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up_date	2024-07-03T20:33:55.368Z
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A neglected neurodegenerative disease: Adult-onset globoid cell leukodystrophy

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