Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants

Optimal time to surgical ligation of patent ductus arteriosus (PDA) in very-low-birth-weight (< 1500 g) premature infants remains an area of controversy. We compared the outcomes of early or late ligation of medical refractory PDA in very-low-birth-weight premature infants. Fifty-six infants unde...
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Autor*in:	Chien-Chou Hsiao [verfasserIn] Jen-Tien Wung [verfasserIn] Lon-Yen Tsao [verfasserIn] Weng-Cheng Chang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2009

Schlagwörter:	indomethacin patent ductus arteriosus prematurity surgery

Übergeordnetes Werk:	In: Journal of the Formosan Medical Association - Elsevier, 2017, 108(2009), 1, Seite 72-77
Übergeordnetes Werk:	volume:108 ; year:2009 ; number:1 ; pages:72-77

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/S0929-6646(09)60035-8

Katalog-ID:	DOAJ079442781

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allfieldsSound	10.1016/S0929-6646(09)60035-8 doi (DE-627)DOAJ079442781 (DE-599)DOAJ2984bcb522c7463c910c84c65f407ea1 DE-627 ger DE-627 rakwb eng R5-920 Chien-Chou Hsiao verfasserin aut Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Optimal time to surgical ligation of patent ductus arteriosus (PDA) in very-low-birth-weight (< 1500 g) premature infants remains an area of controversy. We compared the outcomes of early or late ligation of medical refractory PDA in very-low-birth-weight premature infants. Fifty-six infants underwent surgical closure of PDA after failure of or having contraindications to medical treatment. Thirteen infants were in the early ligation (≤ 14 days) and 43 in the late ligation (< 14 days) groups. Basic clinical features, major morbidity of prematurity and mortality were compared. Clinical features and major outcomes were similar. The early ligation group had earlier onset of symptomatic PDA (5.7 ± 1.6 days vs. 8.1 ± 3.6 days, p = 0.024), and fewer days of total parenteral nutrition (TPN) (39.6 ± 13.9 days vs. 60.4 ± 31.4 days, p = 0.025) and ventilator use (11.1 ± 6.7 days vs. 18.6 ± 10.5 days, p = 0.019). Early ligation of medical refractory PDA in very-low-birth-weight premature infants improves enteral feeding tolerance and reduces TPN and ventilator use, but long-term benefits need further investigation. indomethacin patent ductus arteriosus prematurity surgery Medicine (General) Jen-Tien Wung verfasserin aut Lon-Yen Tsao verfasserin aut Weng-Cheng Chang verfasserin aut In Journal of the Formosan Medical Association Elsevier, 2017 108(2009), 1, Seite 72-77 (DE-627)517812649 (DE-600)2250901-X 09296646 nnns volume:108 year:2009 number:1 pages:72-77 https://doi.org/10.1016/S0929-6646(09)60035-8 kostenfrei https://doaj.org/article/2984bcb522c7463c910c84c65f407ea1 kostenfrei http://www.sciencedirect.com/science/article/pii/S0929664609600358 kostenfrei https://doaj.org/toc/0929-6646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 108 2009 1 72-77
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callnumber-first	R - Medicine
author	Chien-Chou Hsiao
spellingShingle	Chien-Chou Hsiao misc R5-920 misc indomethacin misc patent ductus arteriosus misc prematurity misc surgery misc Medicine (General) Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants
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topic_title	R5-920 Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants indomethacin patent ductus arteriosus prematurity surgery
topic	misc R5-920 misc indomethacin misc patent ductus arteriosus misc prematurity misc surgery misc Medicine (General)
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title	Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants
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title_full	Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants
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title_sort	early or late surgical ligation of medical refractory patent ductus arteriosus in premature infants
callnumber	R5-920
title_auth	Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants
abstract	Optimal time to surgical ligation of patent ductus arteriosus (PDA) in very-low-birth-weight (< 1500 g) premature infants remains an area of controversy. We compared the outcomes of early or late ligation of medical refractory PDA in very-low-birth-weight premature infants. Fifty-six infants underwent surgical closure of PDA after failure of or having contraindications to medical treatment. Thirteen infants were in the early ligation (≤ 14 days) and 43 in the late ligation (< 14 days) groups. Basic clinical features, major morbidity of prematurity and mortality were compared. Clinical features and major outcomes were similar. The early ligation group had earlier onset of symptomatic PDA (5.7 ± 1.6 days vs. 8.1 ± 3.6 days, p = 0.024), and fewer days of total parenteral nutrition (TPN) (39.6 ± 13.9 days vs. 60.4 ± 31.4 days, p = 0.025) and ventilator use (11.1 ± 6.7 days vs. 18.6 ± 10.5 days, p = 0.019). Early ligation of medical refractory PDA in very-low-birth-weight premature infants improves enteral feeding tolerance and reduces TPN and ventilator use, but long-term benefits need further investigation.
abstractGer	Optimal time to surgical ligation of patent ductus arteriosus (PDA) in very-low-birth-weight (< 1500 g) premature infants remains an area of controversy. We compared the outcomes of early or late ligation of medical refractory PDA in very-low-birth-weight premature infants. Fifty-six infants underwent surgical closure of PDA after failure of or having contraindications to medical treatment. Thirteen infants were in the early ligation (≤ 14 days) and 43 in the late ligation (< 14 days) groups. Basic clinical features, major morbidity of prematurity and mortality were compared. Clinical features and major outcomes were similar. The early ligation group had earlier onset of symptomatic PDA (5.7 ± 1.6 days vs. 8.1 ± 3.6 days, p = 0.024), and fewer days of total parenteral nutrition (TPN) (39.6 ± 13.9 days vs. 60.4 ± 31.4 days, p = 0.025) and ventilator use (11.1 ± 6.7 days vs. 18.6 ± 10.5 days, p = 0.019). Early ligation of medical refractory PDA in very-low-birth-weight premature infants improves enteral feeding tolerance and reduces TPN and ventilator use, but long-term benefits need further investigation.
abstract_unstemmed	Optimal time to surgical ligation of patent ductus arteriosus (PDA) in very-low-birth-weight (< 1500 g) premature infants remains an area of controversy. We compared the outcomes of early or late ligation of medical refractory PDA in very-low-birth-weight premature infants. Fifty-six infants underwent surgical closure of PDA after failure of or having contraindications to medical treatment. Thirteen infants were in the early ligation (≤ 14 days) and 43 in the late ligation (< 14 days) groups. Basic clinical features, major morbidity of prematurity and mortality were compared. Clinical features and major outcomes were similar. The early ligation group had earlier onset of symptomatic PDA (5.7 ± 1.6 days vs. 8.1 ± 3.6 days, p = 0.024), and fewer days of total parenteral nutrition (TPN) (39.6 ± 13.9 days vs. 60.4 ± 31.4 days, p = 0.025) and ventilator use (11.1 ± 6.7 days vs. 18.6 ± 10.5 days, p = 0.019). Early ligation of medical refractory PDA in very-low-birth-weight premature infants improves enteral feeding tolerance and reduces TPN and ventilator use, but long-term benefits need further investigation.
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title_short	Early or Late Surgical Ligation of Medical Refractory Patent Ductus Arteriosus in Premature Infants
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