Pulmonary hypertension associated with left-sided heart disease

Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In...
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Autor*in:	Micha T. Maeder [verfasserIn] Otto D. Schoch [verfasserIn] Rebekka Kleiner [verfasserIn] Lucas Joerg [verfasserIn] Daniel Weilenmann [verfasserIn] Swiss Medical Weekly [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation

Übergeordnetes Werk:	In: Swiss Medical Weekly - SMW supporting association (Trägerverein Swiss Medical Weekly SMW), 2003, 147(2017), 0304
Übergeordnetes Werk:	volume:147 ; year:2017 ; number:0304

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.57187/smw.2017.14395

Katalog-ID:	DOAJ079725341

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520			\|a Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD.
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allfields	10.57187/smw.2017.14395 doi (DE-627)DOAJ079725341 (DE-599)DOAJ5dfed82d5f38405591171e0431445068 DE-627 ger DE-627 rakwb eng Micha T. Maeder verfasserin aut Pulmonary hypertension associated with left-sided heart disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD. echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation Medicine R Otto D. Schoch verfasserin aut Rebekka Kleiner verfasserin aut Lucas Joerg verfasserin aut Daniel Weilenmann verfasserin aut Swiss Medical Weekly verfasserin aut In Swiss Medical Weekly SMW supporting association (Trägerverein Swiss Medical Weekly SMW), 2003 147(2017), 0304 (DE-627)324825811 (DE-600)2031164-3 14243997 nnns volume:147 year:2017 number:0304 https://doi.org/10.57187/smw.2017.14395 kostenfrei https://doaj.org/article/5dfed82d5f38405591171e0431445068 kostenfrei https://www.smw.ch/index.php/smw/article/view/2265 kostenfrei https://doaj.org/toc/1424-3997 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 147 2017 0304
spelling	10.57187/smw.2017.14395 doi (DE-627)DOAJ079725341 (DE-599)DOAJ5dfed82d5f38405591171e0431445068 DE-627 ger DE-627 rakwb eng Micha T. Maeder verfasserin aut Pulmonary hypertension associated with left-sided heart disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD. echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation Medicine R Otto D. Schoch verfasserin aut Rebekka Kleiner verfasserin aut Lucas Joerg verfasserin aut Daniel Weilenmann verfasserin aut Swiss Medical Weekly verfasserin aut In Swiss Medical Weekly SMW supporting association (Trägerverein Swiss Medical Weekly SMW), 2003 147(2017), 0304 (DE-627)324825811 (DE-600)2031164-3 14243997 nnns volume:147 year:2017 number:0304 https://doi.org/10.57187/smw.2017.14395 kostenfrei https://doaj.org/article/5dfed82d5f38405591171e0431445068 kostenfrei https://www.smw.ch/index.php/smw/article/view/2265 kostenfrei https://doaj.org/toc/1424-3997 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 147 2017 0304
allfields_unstemmed	10.57187/smw.2017.14395 doi (DE-627)DOAJ079725341 (DE-599)DOAJ5dfed82d5f38405591171e0431445068 DE-627 ger DE-627 rakwb eng Micha T. Maeder verfasserin aut Pulmonary hypertension associated with left-sided heart disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD. echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation Medicine R Otto D. Schoch verfasserin aut Rebekka Kleiner verfasserin aut Lucas Joerg verfasserin aut Daniel Weilenmann verfasserin aut Swiss Medical Weekly verfasserin aut In Swiss Medical Weekly SMW supporting association (Trägerverein Swiss Medical Weekly SMW), 2003 147(2017), 0304 (DE-627)324825811 (DE-600)2031164-3 14243997 nnns volume:147 year:2017 number:0304 https://doi.org/10.57187/smw.2017.14395 kostenfrei https://doaj.org/article/5dfed82d5f38405591171e0431445068 kostenfrei https://www.smw.ch/index.php/smw/article/view/2265 kostenfrei https://doaj.org/toc/1424-3997 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 147 2017 0304
allfieldsGer	10.57187/smw.2017.14395 doi (DE-627)DOAJ079725341 (DE-599)DOAJ5dfed82d5f38405591171e0431445068 DE-627 ger DE-627 rakwb eng Micha T. Maeder verfasserin aut Pulmonary hypertension associated with left-sided heart disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD. echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation Medicine R Otto D. Schoch verfasserin aut Rebekka Kleiner verfasserin aut Lucas Joerg verfasserin aut Daniel Weilenmann verfasserin aut Swiss Medical Weekly verfasserin aut In Swiss Medical Weekly SMW supporting association (Trägerverein Swiss Medical Weekly SMW), 2003 147(2017), 0304 (DE-627)324825811 (DE-600)2031164-3 14243997 nnns volume:147 year:2017 number:0304 https://doi.org/10.57187/smw.2017.14395 kostenfrei https://doaj.org/article/5dfed82d5f38405591171e0431445068 kostenfrei https://www.smw.ch/index.php/smw/article/view/2265 kostenfrei https://doaj.org/toc/1424-3997 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 147 2017 0304
allfieldsSound	10.57187/smw.2017.14395 doi (DE-627)DOAJ079725341 (DE-599)DOAJ5dfed82d5f38405591171e0431445068 DE-627 ger DE-627 rakwb eng Micha T. Maeder verfasserin aut Pulmonary hypertension associated with left-sided heart disease 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD. echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation Medicine R Otto D. Schoch verfasserin aut Rebekka Kleiner verfasserin aut Lucas Joerg verfasserin aut Daniel Weilenmann verfasserin aut Swiss Medical Weekly verfasserin aut In Swiss Medical Weekly SMW supporting association (Trägerverein Swiss Medical Weekly SMW), 2003 147(2017), 0304 (DE-627)324825811 (DE-600)2031164-3 14243997 nnns volume:147 year:2017 number:0304 https://doi.org/10.57187/smw.2017.14395 kostenfrei https://doaj.org/article/5dfed82d5f38405591171e0431445068 kostenfrei https://www.smw.ch/index.php/smw/article/view/2265 kostenfrei https://doaj.org/toc/1424-3997 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 147 2017 0304
language	English
source	In Swiss Medical Weekly 147(2017), 0304 volume:147 year:2017 number:0304
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topic_facet	echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation Medicine R
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container_title	Swiss Medical Weekly
authorswithroles_txt_mv	Micha T. Maeder @@aut@@ Otto D. Schoch @@aut@@ Rebekka Kleiner @@aut@@ Lucas Joerg @@aut@@ Daniel Weilenmann @@aut@@ Swiss Medical Weekly @@aut@@
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author	Micha T. Maeder
spellingShingle	Micha T. Maeder misc echocardiography misc left heart disease misc postcapillary misc pulmonary hypertension misc pulmonary venous hypertension misc right heart catheterisation misc Medicine misc R Pulmonary hypertension associated with left-sided heart disease
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topic_title	Pulmonary hypertension associated with left-sided heart disease echocardiography left heart disease postcapillary pulmonary hypertension pulmonary venous hypertension right heart catheterisation
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title	Pulmonary hypertension associated with left-sided heart disease
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title_sort	pulmonary hypertension associated with left-sided heart disease
title_auth	Pulmonary hypertension associated with left-sided heart disease
abstract	Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD.
abstractGer	Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD.
abstract_unstemmed	Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease, more severe symptoms, and worse prognosis. In contrast to pulmonary arterial hypertension, PH-LHD is characterised by an elevated pulmonary artery wedge pressure (postcapillary pulmonary hypertension) without or with an additional precapillary component (isolated postcapillary vs combined postcapillary and precapillary pulmonary hypertension). Transthoracic echocardiography is the primary noninvasive imaging tool to estimate the probability of pulmonary hypertension and to establish a working diagnosis on the mechanism of pulmonary hypertension. However, right heart catheterisation is always required if significant pulmonary hypertension is suspected and exact knowledge of the haemodynamic constellation is necessary. The haemodynamic constellation (mean pulmonary artery pressure, mean pulmonary artery wedge pressure, left ventricular end-diastolic pressure) in combination with clinical information and imaging findings (mainly echocardiography, coronary angiography and cardiac magnetic resonance imaging) will usually allow the exact mechanism underlying PH-LHD to be defined, which is a prerequisite for appropriate treatment. The general principle for the management of PH-LHD is to treat the underlying left-sided heart disease in an optimal manner using drugs and/or interventional or surgical therapy. There is currently no established indication for pulmonary arterial hypertension-specific therapies in PH-LHD, and specific therapies may even cause harm in patients with PH-LHD.
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title_short	Pulmonary hypertension associated with left-sided heart disease
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Pulmonary hypertension associated with left-sided heart disease

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