Pulmonary recovery from COVID-19 in patients with metabolic diseases: a longitudinal prospective cohort study
Abstract The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A...
Ausführliche Beschreibung
Autor*in: |
Thomas Sonnweber [verfasserIn] Philipp Grubwieser [verfasserIn] Alex Pizzini [verfasserIn] Anna Boehm [verfasserIn] Sabina Sahanic [verfasserIn] Anna Luger [verfasserIn] Christoph Schwabl [verfasserIn] Gerlig Widmann [verfasserIn] Alexander Egger [verfasserIn] Gregor Hoermann [verfasserIn] Ewald Wöll [verfasserIn] Bernhard Puchner [verfasserIn] Susanne Kaser [verfasserIn] Igor Theurl [verfasserIn] Manfred Nairz [verfasserIn] Piotr Tymoszuk [verfasserIn] Günter Weiss [verfasserIn] Michael Joannidis [verfasserIn] Judith Löffler-Ragg [verfasserIn] Ivan Tancevski [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2023 |
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Übergeordnetes Werk: |
In: Scientific Reports - Nature Portfolio, 2011, 13(2023), 1, Seite 12 |
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Übergeordnetes Werk: |
volume:13 ; year:2023 ; number:1 ; pages:12 |
Links: |
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DOI / URN: |
10.1038/s41598-023-29654-1 |
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Katalog-ID: |
DOAJ079910866 |
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10.1038/s41598-023-29654-1 doi (DE-627)DOAJ079910866 (DE-599)DOAJ7632b4a279f8450f8207d5bdfb4d585b DE-627 ger DE-627 rakwb eng Thomas Sonnweber verfasserin aut Pulmonary recovery from COVID-19 in patients with metabolic diseases: a longitudinal prospective cohort study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A total of 145 COVID-19 patients were prospectively followed and a comprehensive clinical, laboratory and imaging assessment was performed at 60, 100, 180, and 360 days after the onset of COVID-19. The severity of acute COVID-19 and outcome at early post-acute follow-up were significantly related to the presence of dysglycemia and dyslipidemia. Still, at long-term follow-up, metabolic disorders were not associated with an adverse pulmonary outcome, as reflected by a good recovery of structural lung abnormalities in both, patients with and without metabolic diseases. To conclude, dyslipidemia and dysglycemia are associated with a more severe course of acute COVID-19 as well as delayed early recovery but do not impair long-term pulmonary recovery. Medicine R Science Q Philipp Grubwieser verfasserin aut Alex Pizzini verfasserin aut Anna Boehm verfasserin aut Sabina Sahanic verfasserin aut Anna Luger verfasserin aut Christoph Schwabl verfasserin aut Gerlig Widmann verfasserin aut Alexander Egger verfasserin aut Gregor Hoermann verfasserin aut Ewald Wöll verfasserin aut Bernhard Puchner verfasserin aut Susanne Kaser verfasserin aut Igor Theurl verfasserin aut Manfred Nairz verfasserin aut Piotr Tymoszuk verfasserin aut Günter Weiss verfasserin aut Michael Joannidis verfasserin aut Judith Löffler-Ragg verfasserin aut Ivan Tancevski verfasserin aut In Scientific Reports Nature Portfolio, 2011 13(2023), 1, Seite 12 (DE-627)663366712 (DE-600)2615211-3 20452322 nnns volume:13 year:2023 number:1 pages:12 https://doi.org/10.1038/s41598-023-29654-1 kostenfrei https://doaj.org/article/7632b4a279f8450f8207d5bdfb4d585b kostenfrei https://doi.org/10.1038/s41598-023-29654-1 kostenfrei https://doaj.org/toc/2045-2322 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_381 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1 12 |
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10.1038/s41598-023-29654-1 doi (DE-627)DOAJ079910866 (DE-599)DOAJ7632b4a279f8450f8207d5bdfb4d585b DE-627 ger DE-627 rakwb eng Thomas Sonnweber verfasserin aut Pulmonary recovery from COVID-19 in patients with metabolic diseases: a longitudinal prospective cohort study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A total of 145 COVID-19 patients were prospectively followed and a comprehensive clinical, laboratory and imaging assessment was performed at 60, 100, 180, and 360 days after the onset of COVID-19. The severity of acute COVID-19 and outcome at early post-acute follow-up were significantly related to the presence of dysglycemia and dyslipidemia. Still, at long-term follow-up, metabolic disorders were not associated with an adverse pulmonary outcome, as reflected by a good recovery of structural lung abnormalities in both, patients with and without metabolic diseases. To conclude, dyslipidemia and dysglycemia are associated with a more severe course of acute COVID-19 as well as delayed early recovery but do not impair long-term pulmonary recovery. Medicine R Science Q Philipp Grubwieser verfasserin aut Alex Pizzini verfasserin aut Anna Boehm verfasserin aut Sabina Sahanic verfasserin aut Anna Luger verfasserin aut Christoph Schwabl verfasserin aut Gerlig Widmann verfasserin aut Alexander Egger verfasserin aut Gregor Hoermann verfasserin aut Ewald Wöll verfasserin aut Bernhard Puchner verfasserin aut Susanne Kaser verfasserin aut Igor Theurl verfasserin aut Manfred Nairz verfasserin aut Piotr Tymoszuk verfasserin aut Günter Weiss verfasserin aut Michael Joannidis verfasserin aut Judith Löffler-Ragg verfasserin aut Ivan Tancevski verfasserin aut In Scientific Reports Nature Portfolio, 2011 13(2023), 1, Seite 12 (DE-627)663366712 (DE-600)2615211-3 20452322 nnns volume:13 year:2023 number:1 pages:12 https://doi.org/10.1038/s41598-023-29654-1 kostenfrei https://doaj.org/article/7632b4a279f8450f8207d5bdfb4d585b kostenfrei https://doi.org/10.1038/s41598-023-29654-1 kostenfrei https://doaj.org/toc/2045-2322 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_381 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1 12 |
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10.1038/s41598-023-29654-1 doi (DE-627)DOAJ079910866 (DE-599)DOAJ7632b4a279f8450f8207d5bdfb4d585b DE-627 ger DE-627 rakwb eng Thomas Sonnweber verfasserin aut Pulmonary recovery from COVID-19 in patients with metabolic diseases: a longitudinal prospective cohort study 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A total of 145 COVID-19 patients were prospectively followed and a comprehensive clinical, laboratory and imaging assessment was performed at 60, 100, 180, and 360 days after the onset of COVID-19. The severity of acute COVID-19 and outcome at early post-acute follow-up were significantly related to the presence of dysglycemia and dyslipidemia. Still, at long-term follow-up, metabolic disorders were not associated with an adverse pulmonary outcome, as reflected by a good recovery of structural lung abnormalities in both, patients with and without metabolic diseases. To conclude, dyslipidemia and dysglycemia are associated with a more severe course of acute COVID-19 as well as delayed early recovery but do not impair long-term pulmonary recovery. Medicine R Science Q Philipp Grubwieser verfasserin aut Alex Pizzini verfasserin aut Anna Boehm verfasserin aut Sabina Sahanic verfasserin aut Anna Luger verfasserin aut Christoph Schwabl verfasserin aut Gerlig Widmann verfasserin aut Alexander Egger verfasserin aut Gregor Hoermann verfasserin aut Ewald Wöll verfasserin aut Bernhard Puchner verfasserin aut Susanne Kaser verfasserin aut Igor Theurl verfasserin aut Manfred Nairz verfasserin aut Piotr Tymoszuk verfasserin aut Günter Weiss verfasserin aut Michael Joannidis verfasserin aut Judith Löffler-Ragg verfasserin aut Ivan Tancevski verfasserin aut In Scientific Reports Nature Portfolio, 2011 13(2023), 1, Seite 12 (DE-627)663366712 (DE-600)2615211-3 20452322 nnns volume:13 year:2023 number:1 pages:12 https://doi.org/10.1038/s41598-023-29654-1 kostenfrei https://doaj.org/article/7632b4a279f8450f8207d5bdfb4d585b kostenfrei https://doi.org/10.1038/s41598-023-29654-1 kostenfrei https://doaj.org/toc/2045-2322 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_381 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1 12 |
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pulmonary recovery from covid-19 in patients with metabolic diseases: a longitudinal prospective cohort study |
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Pulmonary recovery from COVID-19 in patients with metabolic diseases: a longitudinal prospective cohort study |
abstract |
Abstract The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A total of 145 COVID-19 patients were prospectively followed and a comprehensive clinical, laboratory and imaging assessment was performed at 60, 100, 180, and 360 days after the onset of COVID-19. The severity of acute COVID-19 and outcome at early post-acute follow-up were significantly related to the presence of dysglycemia and dyslipidemia. Still, at long-term follow-up, metabolic disorders were not associated with an adverse pulmonary outcome, as reflected by a good recovery of structural lung abnormalities in both, patients with and without metabolic diseases. To conclude, dyslipidemia and dysglycemia are associated with a more severe course of acute COVID-19 as well as delayed early recovery but do not impair long-term pulmonary recovery. |
abstractGer |
Abstract The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A total of 145 COVID-19 patients were prospectively followed and a comprehensive clinical, laboratory and imaging assessment was performed at 60, 100, 180, and 360 days after the onset of COVID-19. The severity of acute COVID-19 and outcome at early post-acute follow-up were significantly related to the presence of dysglycemia and dyslipidemia. Still, at long-term follow-up, metabolic disorders were not associated with an adverse pulmonary outcome, as reflected by a good recovery of structural lung abnormalities in both, patients with and without metabolic diseases. To conclude, dyslipidemia and dysglycemia are associated with a more severe course of acute COVID-19 as well as delayed early recovery but do not impair long-term pulmonary recovery. |
abstract_unstemmed |
Abstract The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A total of 145 COVID-19 patients were prospectively followed and a comprehensive clinical, laboratory and imaging assessment was performed at 60, 100, 180, and 360 days after the onset of COVID-19. The severity of acute COVID-19 and outcome at early post-acute follow-up were significantly related to the presence of dysglycemia and dyslipidemia. Still, at long-term follow-up, metabolic disorders were not associated with an adverse pulmonary outcome, as reflected by a good recovery of structural lung abnormalities in both, patients with and without metabolic diseases. To conclude, dyslipidemia and dysglycemia are associated with a more severe course of acute COVID-19 as well as delayed early recovery but do not impair long-term pulmonary recovery. |
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title_short |
Pulmonary recovery from COVID-19 in patients with metabolic diseases: a longitudinal prospective cohort study |
url |
https://doi.org/10.1038/s41598-023-29654-1 https://doaj.org/article/7632b4a279f8450f8207d5bdfb4d585b https://doaj.org/toc/2045-2322 |
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Philipp Grubwieser Alex Pizzini Anna Boehm Sabina Sahanic Anna Luger Christoph Schwabl Gerlig Widmann Alexander Egger Gregor Hoermann Ewald Wöll Bernhard Puchner Susanne Kaser Igor Theurl Manfred Nairz Piotr Tymoszuk Günter Weiss Michael Joannidis Judith Löffler-Ragg Ivan Tancevski |
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up_date |
2024-07-04T01:18:38.442Z |
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