Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany

<i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Annette Eidmann [verfasserIn] Yama Kamawal [verfasserIn] Martin Luedemann [verfasserIn] Peter Raab [verfasserIn] Maximilian Rudert [verfasserIn] Ioannis Stratos [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	lower extremity amputation major amputation minor amputation orthopaedic surgery

Übergeordnetes Werk:	In: Medicina - MDPI AG, 2016, 59(2023), 2, p 200
Übergeordnetes Werk:	volume:59 ; year:2023 ; number:2, p 200

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3390/medicina59020200

Katalog-ID:	DOAJ080218318

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520			\|a <i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation.
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allfields	10.3390/medicina59020200 doi (DE-627)DOAJ080218318 (DE-599)DOAJ68d8ca4ce41a467f8d6f1ceee0f72e5f DE-627 ger DE-627 rakwb eng R5-920 Annette Eidmann verfasserin aut Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation. lower extremity amputation major amputation minor amputation orthopaedic surgery Medicine (General) Yama Kamawal verfasserin aut Martin Luedemann verfasserin aut Peter Raab verfasserin aut Maximilian Rudert verfasserin aut Ioannis Stratos verfasserin aut In Medicina MDPI AG, 2016 59(2023), 2, p 200 (DE-627)354543296 (DE-600)2088820-X 16489144 nnns volume:59 year:2023 number:2, p 200 https://doi.org/10.3390/medicina59020200 kostenfrei https://doaj.org/article/68d8ca4ce41a467f8d6f1ceee0f72e5f kostenfrei https://www.mdpi.com/1648-9144/59/2/200 kostenfrei https://doaj.org/toc/1010-660X Journal toc kostenfrei https://doaj.org/toc/1648-9144 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 59 2023 2, p 200
spelling	10.3390/medicina59020200 doi (DE-627)DOAJ080218318 (DE-599)DOAJ68d8ca4ce41a467f8d6f1ceee0f72e5f DE-627 ger DE-627 rakwb eng R5-920 Annette Eidmann verfasserin aut Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation. lower extremity amputation major amputation minor amputation orthopaedic surgery Medicine (General) Yama Kamawal verfasserin aut Martin Luedemann verfasserin aut Peter Raab verfasserin aut Maximilian Rudert verfasserin aut Ioannis Stratos verfasserin aut In Medicina MDPI AG, 2016 59(2023), 2, p 200 (DE-627)354543296 (DE-600)2088820-X 16489144 nnns volume:59 year:2023 number:2, p 200 https://doi.org/10.3390/medicina59020200 kostenfrei https://doaj.org/article/68d8ca4ce41a467f8d6f1ceee0f72e5f kostenfrei https://www.mdpi.com/1648-9144/59/2/200 kostenfrei https://doaj.org/toc/1010-660X Journal toc kostenfrei https://doaj.org/toc/1648-9144 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 59 2023 2, p 200
allfields_unstemmed	10.3390/medicina59020200 doi (DE-627)DOAJ080218318 (DE-599)DOAJ68d8ca4ce41a467f8d6f1ceee0f72e5f DE-627 ger DE-627 rakwb eng R5-920 Annette Eidmann verfasserin aut Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation. lower extremity amputation major amputation minor amputation orthopaedic surgery Medicine (General) Yama Kamawal verfasserin aut Martin Luedemann verfasserin aut Peter Raab verfasserin aut Maximilian Rudert verfasserin aut Ioannis Stratos verfasserin aut In Medicina MDPI AG, 2016 59(2023), 2, p 200 (DE-627)354543296 (DE-600)2088820-X 16489144 nnns volume:59 year:2023 number:2, p 200 https://doi.org/10.3390/medicina59020200 kostenfrei https://doaj.org/article/68d8ca4ce41a467f8d6f1ceee0f72e5f kostenfrei https://www.mdpi.com/1648-9144/59/2/200 kostenfrei https://doaj.org/toc/1010-660X Journal toc kostenfrei https://doaj.org/toc/1648-9144 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 59 2023 2, p 200
allfieldsGer	10.3390/medicina59020200 doi (DE-627)DOAJ080218318 (DE-599)DOAJ68d8ca4ce41a467f8d6f1ceee0f72e5f DE-627 ger DE-627 rakwb eng R5-920 Annette Eidmann verfasserin aut Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation. lower extremity amputation major amputation minor amputation orthopaedic surgery Medicine (General) Yama Kamawal verfasserin aut Martin Luedemann verfasserin aut Peter Raab verfasserin aut Maximilian Rudert verfasserin aut Ioannis Stratos verfasserin aut In Medicina MDPI AG, 2016 59(2023), 2, p 200 (DE-627)354543296 (DE-600)2088820-X 16489144 nnns volume:59 year:2023 number:2, p 200 https://doi.org/10.3390/medicina59020200 kostenfrei https://doaj.org/article/68d8ca4ce41a467f8d6f1ceee0f72e5f kostenfrei https://www.mdpi.com/1648-9144/59/2/200 kostenfrei https://doaj.org/toc/1010-660X Journal toc kostenfrei https://doaj.org/toc/1648-9144 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 59 2023 2, p 200
allfieldsSound	10.3390/medicina59020200 doi (DE-627)DOAJ080218318 (DE-599)DOAJ68d8ca4ce41a467f8d6f1ceee0f72e5f DE-627 ger DE-627 rakwb eng R5-920 Annette Eidmann verfasserin aut Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation. lower extremity amputation major amputation minor amputation orthopaedic surgery Medicine (General) Yama Kamawal verfasserin aut Martin Luedemann verfasserin aut Peter Raab verfasserin aut Maximilian Rudert verfasserin aut Ioannis Stratos verfasserin aut In Medicina MDPI AG, 2016 59(2023), 2, p 200 (DE-627)354543296 (DE-600)2088820-X 16489144 nnns volume:59 year:2023 number:2, p 200 https://doi.org/10.3390/medicina59020200 kostenfrei https://doaj.org/article/68d8ca4ce41a467f8d6f1ceee0f72e5f kostenfrei https://www.mdpi.com/1648-9144/59/2/200 kostenfrei https://doaj.org/toc/1010-660X Journal toc kostenfrei https://doaj.org/toc/1648-9144 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 59 2023 2, p 200
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title	Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany
ctrlnum	(DE-627)DOAJ080218318 (DE-599)DOAJ68d8ca4ce41a467f8d6f1ceee0f72e5f
title_full	Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany
author_sort	Annette Eidmann
journal	Medicina
journalStr	Medicina
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author_browse	Annette Eidmann Yama Kamawal Martin Luedemann Peter Raab Maximilian Rudert Ioannis Stratos
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title_sort	demographics and etiology for lower extremity amputations—experiences of an university orthopaedic center in germany
callnumber	R5-920
title_auth	Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany
abstract	<i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation.
abstractGer	<i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation.
abstract_unstemmed	<i<Background and Objectives</i<: Currently, the worldwide incidence of major amputations in the general population is decreasing whereas the incidence of minor amputations is increasing. The purpose of our study was to analyze whether this trend is reflected among orthopaedic patients treated with lower extremity amputation in our orthopaedic university institution. <i<Materials and Methods</i<: We conducted a single-center retrospective study and included patients referred to our orthopaedic department for lower extremity amputation (LEA) between January 2007 and December 2019. Acquired data were the year of amputation, age, sex, level of amputation and cause of amputation. T test and Chi² test were performed to compare age and amputation rates between males and females; significance was defined as <i<p</i< < 0.05. Linear regression and multivariate logistic regression models were used to test time trends and to calculate probabilities for LEA. <i<Results</i<: A total of 114 amputations of the lower extremity were performed, of which 60.5% were major amputations. The number of major amputations increased over time with a rate of 0.6 amputation/year. Men were significantly more often affected by LEA than women. Age of LEA for men was significantly below the age of LEA for women (men: 54.8 ± 2.8 years, women: 64.9 ± 3.2 years, <i<p</i< = 0.021). Main causes leading to LEA were tumors (28.9%) and implant-associated complications (25.4%). Implant-associated complications and age raised the probability for major amputation, whereas malformation, angiopathies and infections were more likely to cause a minor amputation. <i<Conclusions</i<: Among patients in our orthopaedic institution, etiology of amputations of the lower extremity is multifactorial and differs from other surgical specialties. The number of major amputations has increased continuously over the past years. Age and sex, as well as diagnosis, influence the type and level of amputation.
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title_short	Demographics and Etiology for Lower Extremity Amputations—Experiences of an University Orthopaedic Center in Germany
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