Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency

Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional sup...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	V. S. Scherbakha [verfasserIn] O. Z. Okhlobystina [verfasserIn] A. V. Korolev [verfasserIn] O. S. Shifrin [verfasserIn] A. V. Stepanov [verfasserIn] A. S. Tertychny [verfasserIn] A. V. Okhlobystin [verfasserIn] V. T. Ivashkin [verfasserIn]

Format:	E-Artikel
Sprache:	Russisch

Erschienen:	2018

Schlagwörter:	болезнь крона трофологическая недостаточность

Übergeordnetes Werk:	In: Российский журнал гастроэнтерологии, гепатологии, колопроктологии - Gastro LLC, 2020, 28(2018), 2, Seite 109-116
Übergeordnetes Werk:	volume:28 ; year:2018 ; number:2 ; pages:109-116

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.22416/1382-4376-2018-28-2-109-116

Katalog-ID:	DOAJ083376038

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ083376038
003	DE-627
005	20240414034718.0
007	cr uuu---uuuuu
008	230311s2018 xx \|\|\|\|\|o 00\| \|\|rus c
024	7		\|a 10.22416/1382-4376-2018-28-2-109-116 \|2 doi
035			\|a (DE-627)DOAJ083376038
035			\|a (DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a rus
050		0	\|a RC799-869
100	0		\|a V. S. Scherbakha \|e verfasserin \|4 aut
245	1	0	\|a Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency
264		1	\|c 2018
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages
650		4	\|a болезнь крона
650		4	\|a трофологическая недостаточность
653		0	\|a Diseases of the digestive system. Gastroenterology
700	0		\|a O. Z. Okhlobystina \|e verfasserin \|4 aut
700	0		\|a A. V. Korolev \|e verfasserin \|4 aut
700	0		\|a O. S. Shifrin \|e verfasserin \|4 aut
700	0		\|a A. V. Stepanov \|e verfasserin \|4 aut
700	0		\|a A. S. Tertychny \|e verfasserin \|4 aut
700	0		\|a A. V. Okhlobystin \|e verfasserin \|4 aut
700	0		\|a V. T. Ivashkin \|e verfasserin \|4 aut
773	0	8	\|i In \|t Российский журнал гастроэнтерологии, гепатологии, колопроктологии \|d Gastro LLC, 2020 \|g 28(2018), 2, Seite 109-116 \|w (DE-627)1698164203 \|x 26586673 \|7 nnns
773	1	8	\|g volume:28 \|g year:2018 \|g number:2 \|g pages:109-116
856	4	0	\|u https://doi.org/10.22416/1382-4376-2018-28-2-109-116 \|z kostenfrei
856	4	0	\|u https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e \|z kostenfrei
856	4	0	\|u https://www.gastro-j.ru/jour/article/view/234 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1382-4376 \|y Journal toc \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/2658-6673 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 28 \|j 2018 \|e 2 \|h 109-116

Indexfelder

author_variant	v s s vss o z o ozo a v k avk o s s oss a v s avs a s t ast a v o avo v t i vti
matchkey_str	article:26586673:2018----::lnclon2yaodainwtiiilyigoecondsaensvr
hierarchy_sort_str	2018
callnumber-subject-code	RC
publishDate	2018
allfields	10.22416/1382-4376-2018-28-2-109-116 doi (DE-627)DOAJ083376038 (DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e DE-627 ger DE-627 rakwb rus RC799-869 V. S. Scherbakha verfasserin aut Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages болезнь крона трофологическая недостаточность Diseases of the digestive system. Gastroenterology O. Z. Okhlobystina verfasserin aut A. V. Korolev verfasserin aut O. S. Shifrin verfasserin aut A. V. Stepanov verfasserin aut A. S. Tertychny verfasserin aut A. V. Okhlobystin verfasserin aut V. T. Ivashkin verfasserin aut In Российский журнал гастроэнтерологии, гепатологии, колопроктологии Gastro LLC, 2020 28(2018), 2, Seite 109-116 (DE-627)1698164203 26586673 nnns volume:28 year:2018 number:2 pages:109-116 https://doi.org/10.22416/1382-4376-2018-28-2-109-116 kostenfrei https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e kostenfrei https://www.gastro-j.ru/jour/article/view/234 kostenfrei https://doaj.org/toc/1382-4376 Journal toc kostenfrei https://doaj.org/toc/2658-6673 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2018 2 109-116
spelling	10.22416/1382-4376-2018-28-2-109-116 doi (DE-627)DOAJ083376038 (DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e DE-627 ger DE-627 rakwb rus RC799-869 V. S. Scherbakha verfasserin aut Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages болезнь крона трофологическая недостаточность Diseases of the digestive system. Gastroenterology O. Z. Okhlobystina verfasserin aut A. V. Korolev verfasserin aut O. S. Shifrin verfasserin aut A. V. Stepanov verfasserin aut A. S. Tertychny verfasserin aut A. V. Okhlobystin verfasserin aut V. T. Ivashkin verfasserin aut In Российский журнал гастроэнтерологии, гепатологии, колопроктологии Gastro LLC, 2020 28(2018), 2, Seite 109-116 (DE-627)1698164203 26586673 nnns volume:28 year:2018 number:2 pages:109-116 https://doi.org/10.22416/1382-4376-2018-28-2-109-116 kostenfrei https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e kostenfrei https://www.gastro-j.ru/jour/article/view/234 kostenfrei https://doaj.org/toc/1382-4376 Journal toc kostenfrei https://doaj.org/toc/2658-6673 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2018 2 109-116
allfields_unstemmed	10.22416/1382-4376-2018-28-2-109-116 doi (DE-627)DOAJ083376038 (DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e DE-627 ger DE-627 rakwb rus RC799-869 V. S. Scherbakha verfasserin aut Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages болезнь крона трофологическая недостаточность Diseases of the digestive system. Gastroenterology O. Z. Okhlobystina verfasserin aut A. V. Korolev verfasserin aut O. S. Shifrin verfasserin aut A. V. Stepanov verfasserin aut A. S. Tertychny verfasserin aut A. V. Okhlobystin verfasserin aut V. T. Ivashkin verfasserin aut In Российский журнал гастроэнтерологии, гепатологии, колопроктологии Gastro LLC, 2020 28(2018), 2, Seite 109-116 (DE-627)1698164203 26586673 nnns volume:28 year:2018 number:2 pages:109-116 https://doi.org/10.22416/1382-4376-2018-28-2-109-116 kostenfrei https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e kostenfrei https://www.gastro-j.ru/jour/article/view/234 kostenfrei https://doaj.org/toc/1382-4376 Journal toc kostenfrei https://doaj.org/toc/2658-6673 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2018 2 109-116
allfieldsGer	10.22416/1382-4376-2018-28-2-109-116 doi (DE-627)DOAJ083376038 (DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e DE-627 ger DE-627 rakwb rus RC799-869 V. S. Scherbakha verfasserin aut Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages болезнь крона трофологическая недостаточность Diseases of the digestive system. Gastroenterology O. Z. Okhlobystina verfasserin aut A. V. Korolev verfasserin aut O. S. Shifrin verfasserin aut A. V. Stepanov verfasserin aut A. S. Tertychny verfasserin aut A. V. Okhlobystin verfasserin aut V. T. Ivashkin verfasserin aut In Российский журнал гастроэнтерологии, гепатологии, колопроктологии Gastro LLC, 2020 28(2018), 2, Seite 109-116 (DE-627)1698164203 26586673 nnns volume:28 year:2018 number:2 pages:109-116 https://doi.org/10.22416/1382-4376-2018-28-2-109-116 kostenfrei https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e kostenfrei https://www.gastro-j.ru/jour/article/view/234 kostenfrei https://doaj.org/toc/1382-4376 Journal toc kostenfrei https://doaj.org/toc/2658-6673 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2018 2 109-116
allfieldsSound	10.22416/1382-4376-2018-28-2-109-116 doi (DE-627)DOAJ083376038 (DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e DE-627 ger DE-627 rakwb rus RC799-869 V. S. Scherbakha verfasserin aut Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages болезнь крона трофологическая недостаточность Diseases of the digestive system. Gastroenterology O. Z. Okhlobystina verfasserin aut A. V. Korolev verfasserin aut O. S. Shifrin verfasserin aut A. V. Stepanov verfasserin aut A. S. Tertychny verfasserin aut A. V. Okhlobystin verfasserin aut V. T. Ivashkin verfasserin aut In Российский журнал гастроэнтерологии, гепатологии, колопроктологии Gastro LLC, 2020 28(2018), 2, Seite 109-116 (DE-627)1698164203 26586673 nnns volume:28 year:2018 number:2 pages:109-116 https://doi.org/10.22416/1382-4376-2018-28-2-109-116 kostenfrei https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e kostenfrei https://www.gastro-j.ru/jour/article/view/234 kostenfrei https://doaj.org/toc/1382-4376 Journal toc kostenfrei https://doaj.org/toc/2658-6673 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 2018 2 109-116
language	Russian
source	In Российский журнал гастроэнтерологии, гепатологии, колопроктологии 28(2018), 2, Seite 109-116 volume:28 year:2018 number:2 pages:109-116
sourceStr	In Российский журнал гастроэнтерологии, гепатологии, колопроктологии 28(2018), 2, Seite 109-116 volume:28 year:2018 number:2 pages:109-116
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	болезнь крона трофологическая недостаточность Diseases of the digestive system. Gastroenterology
isfreeaccess_bool	true
container_title	Российский журнал гастроэнтерологии, гепатологии, колопроктологии
authorswithroles_txt_mv	V. S. Scherbakha @@aut@@ O. Z. Okhlobystina @@aut@@ A. V. Korolev @@aut@@ O. S. Shifrin @@aut@@ A. V. Stepanov @@aut@@ A. S. Tertychny @@aut@@ A. V. Okhlobystin @@aut@@ V. T. Ivashkin @@aut@@
publishDateDaySort_date	2018-01-01T00:00:00Z
hierarchy_top_id	1698164203
id	DOAJ083376038
language_de	russisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ083376038</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240414034718.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230311s2018 xx \|\|\|\|\|o 00\| \|\|rus c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.22416/1382-4376-2018-28-2-109-116</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ083376038</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">rus</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC799-869</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">V. S. Scherbakha</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">болезнь крона</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">трофологическая недостаточность</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Diseases of the digestive system. Gastroenterology</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">O. Z. Okhlobystina</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. V. Korolev</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">O. S. Shifrin</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. V. Stepanov</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. S. Tertychny</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. V. Okhlobystin</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">V. T. Ivashkin</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</subfield><subfield code="d">Gastro LLC, 2020</subfield><subfield code="g">28(2018), 2, Seite 109-116</subfield><subfield code="w">(DE-627)1698164203</subfield><subfield code="x">26586673</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:28</subfield><subfield code="g">year:2018</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:109-116</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.22416/1382-4376-2018-28-2-109-116</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.gastro-j.ru/jour/article/view/234</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1382-4376</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2658-6673</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">28</subfield><subfield code="j">2018</subfield><subfield code="e">2</subfield><subfield code="h">109-116</subfield></datafield></record></collection>
callnumber-first	R - Medicine
author	V. S. Scherbakha
spellingShingle	V. S. Scherbakha misc RC799-869 misc болезнь крона misc трофологическая недостаточность misc Diseases of the digestive system. Gastroenterology Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency
authorStr	V. S. Scherbakha
ppnlink_with_tag_str_mv	@@773@@(DE-627)1698164203
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	RC799-869
illustrated	Not Illustrated
issn	26586673
topic_title	RC799-869 Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency болезнь крона трофологическая недостаточность
topic	misc RC799-869 misc болезнь крона misc трофологическая недостаточность misc Diseases of the digestive system. Gastroenterology
topic_unstemmed	misc RC799-869 misc болезнь крона misc трофологическая недостаточность misc Diseases of the digestive system. Gastroenterology
topic_browse	misc RC799-869 misc болезнь крона misc трофологическая недостаточность misc Diseases of the digestive system. Gastroenterology
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Российский журнал гастроэнтерологии, гепатологии, колопроктологии
hierarchy_parent_id	1698164203
hierarchy_top_title	Российский журнал гастроэнтерологии, гепатологии, колопроктологии
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)1698164203
title	Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency
ctrlnum	(DE-627)DOAJ083376038 (DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e
title_full	Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency
author_sort	V. S. Scherbakha
journal	Российский журнал гастроэнтерологии, гепатологии, колопроктологии
journalStr	Российский журнал гастроэнтерологии, гепатологии, колопроктологии
callnumber-first-code	R
lang_code	rus
isOA_bool	true
recordtype	marc
publishDateSort	2018
contenttype_str_mv	txt
container_start_page	109
author_browse	V. S. Scherbakha O. Z. Okhlobystina A. V. Korolev O. S. Shifrin A. V. Stepanov A. S. Tertychny A. V. Okhlobystin V. T. Ivashkin
container_volume	28
class	RC799-869
format_se	Elektronische Aufsätze
author-letter	V. S. Scherbakha
doi_str_mv	10.22416/1382-4376-2018-28-2-109-116
author2-role	verfasserin
title_sort	clinical round: 27 year old patient with initially diagnosed crohn's disease and severe protein and energy deficiency
callnumber	RC799-869
title_auth	Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency
abstract	Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages
abstractGer	Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages
abstract_unstemmed	Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	2
title_short	Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency
url	https://doi.org/10.22416/1382-4376-2018-28-2-109-116 https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e https://www.gastro-j.ru/jour/article/view/234 https://doaj.org/toc/1382-4376 https://doaj.org/toc/2658-6673
remote_bool	true
author2	O. Z. Okhlobystina A. V. Korolev O. S. Shifrin A. V. Stepanov A. S. Tertychny A. V. Okhlobystin V. T. Ivashkin
author2Str	O. Z. Okhlobystina A. V. Korolev O. S. Shifrin A. V. Stepanov A. S. Tertychny A. V. Okhlobystin V. T. Ivashkin
ppnlink	1698164203
callnumber-subject	RC - Internal Medicine
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.22416/1382-4376-2018-28-2-109-116
callnumber-a	RC799-869
up_date	2024-07-03T17:06:50.475Z
_version_	1803578413391282177
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ083376038</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240414034718.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230311s2018 xx \|\|\|\|\|o 00\| \|\|rus c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.22416/1382-4376-2018-28-2-109-116</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ083376038</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ2c9c500df31b4d1c99b498feee0f318e</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">rus</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC799-869</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">V. S. Scherbakha</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2018</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Aim of case presentation. To demonstrate the course of inflammatory and sclerosing variant of the Crohn’s disease, complicated by severe nutritional failure. Nonetheless good therapeutic response was achieved at combined anti-cytokine therapy with immunosuppressive drugs and adequate nutritional support. Summary. Disease manifested with diarrhea, general weakness, high fever, abdominal pain and significant weight loss. Laboratory tests demonstrated elevation of ESR and C-reactive protein and anemia. Patient was diagnosed as having irritable bowel syndrome in local hospital and received symptomatic treatment for one year. Later on patient underwent examination to exclude hematological disorder. In 1.5 years before admission to Vasilenko clinic of Sechenov University patient lost 30 kg of body weight. The diagnosis of Crohn’s disease in our clinic was established on the basis of careful study of clinical course of disease (late postprandial pain, diarrhea, fever and progressive weight loss). The diagnostic concept was confirmed by modern laboratory and instrumental methods of investigation (CT enterocolonography, endoscopic and histological study). Evaluation of nutritional status revealed the presence of protein-energy malnutrition of severe degree of alimentary marasmus type. Taking into account severe manifestations of a nutritional failure along with baseline therapy of autoimmune process at Crohn's disease (corticosteroids, immunosuppressors added by anticytokine therapy) patients received nutritional support that allowed to achieve clinical remission. Conclusion. Progression of Crohn’s disease with involvement of terminal ileum can result in proteinenergy malnutrition. Management of relapse of Crohn's disease and severe protein-energy malnutrition require nutritional support already at initial treatment stages</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">болезнь крона</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">трофологическая недостаточность</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Diseases of the digestive system. Gastroenterology</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">O. Z. Okhlobystina</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. V. Korolev</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">O. S. Shifrin</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. V. Stepanov</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. S. Tertychny</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. V. Okhlobystin</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">V. T. Ivashkin</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Российский журнал гастроэнтерологии, гепатологии, колопроктологии</subfield><subfield code="d">Gastro LLC, 2020</subfield><subfield code="g">28(2018), 2, Seite 109-116</subfield><subfield code="w">(DE-627)1698164203</subfield><subfield code="x">26586673</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:28</subfield><subfield code="g">year:2018</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:109-116</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.22416/1382-4376-2018-28-2-109-116</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/2c9c500df31b4d1c99b498feee0f318e</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.gastro-j.ru/jour/article/view/234</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1382-4376</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2658-6673</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">28</subfield><subfield code="j">2018</subfield><subfield code="e">2</subfield><subfield code="h">109-116</subfield></datafield></record></collection>
score	7.402316

Nicht das Richtige dabei?

Schreiben Sie uns!

Clinical round: 27 year old patient with initially diagnosed Crohn's disease and severe protein and energy deficiency

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?