Tetraspanin-enriched microdomains: The building blocks of migrasomes

The migrasome is a newly discovered organelle of migrating cells. Migrasomes play diverse physiological roles including mitochondrial quality control, lateral transfer of material between cells, and delivery of signaling molecules to spatially defined locations. The formation of migrasomes is depend...
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Gespeichert in:

Autor*in:	Yuwei Huang [verfasserIn] Li Yu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Migrasome Tetraspanins Microdomains Tetraspanin-enriched microdomains

Übergeordnetes Werk:	In: Cell Insight - Elsevier, 2022, 1(2022), 1, Seite 100003-
Übergeordnetes Werk:	volume:1 ; year:2022 ; number:1 ; pages:100003-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.cellin.2021.100003

Katalog-ID:	DOAJ084739282

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author	Yuwei Huang
spellingShingle	Yuwei Huang misc QH301-705.5 misc R5-920 misc Migrasome misc Tetraspanins misc Microdomains misc Tetraspanin-enriched microdomains misc Biology (General) misc Medicine (General) Tetraspanin-enriched microdomains: The building blocks of migrasomes
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topic_title	QH301-705.5 R5-920 Tetraspanin-enriched microdomains: The building blocks of migrasomes Migrasome Tetraspanins Microdomains Tetraspanin-enriched microdomains
topic	misc QH301-705.5 misc R5-920 misc Migrasome misc Tetraspanins misc Microdomains misc Tetraspanin-enriched microdomains misc Biology (General) misc Medicine (General)
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title_sort	tetraspanin-enriched microdomains: the building blocks of migrasomes
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title_auth	Tetraspanin-enriched microdomains: The building blocks of migrasomes
abstract	The migrasome is a newly discovered organelle of migrating cells. Migrasomes play diverse physiological roles including mitochondrial quality control, lateral transfer of material between cells, and delivery of signaling molecules to spatially defined locations. The formation of migrasomes is dependent on tetraspanins, a group of membrane proteins containing four transmembrane domains, which form membrane microdomains named tetraspanin-enriched microdomains (TEMs). In this review, we will discuss the mechanisms for migrasome biogenesis, with a focus on the role of TEMs and the organizing principles underlying the formation of TEMs.
abstractGer	The migrasome is a newly discovered organelle of migrating cells. Migrasomes play diverse physiological roles including mitochondrial quality control, lateral transfer of material between cells, and delivery of signaling molecules to spatially defined locations. The formation of migrasomes is dependent on tetraspanins, a group of membrane proteins containing four transmembrane domains, which form membrane microdomains named tetraspanin-enriched microdomains (TEMs). In this review, we will discuss the mechanisms for migrasome biogenesis, with a focus on the role of TEMs and the organizing principles underlying the formation of TEMs.
abstract_unstemmed	The migrasome is a newly discovered organelle of migrating cells. Migrasomes play diverse physiological roles including mitochondrial quality control, lateral transfer of material between cells, and delivery of signaling molecules to spatially defined locations. The formation of migrasomes is dependent on tetraspanins, a group of membrane proteins containing four transmembrane domains, which form membrane microdomains named tetraspanin-enriched microdomains (TEMs). In this review, we will discuss the mechanisms for migrasome biogenesis, with a focus on the role of TEMs and the organizing principles underlying the formation of TEMs.
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title_short	Tetraspanin-enriched microdomains: The building blocks of migrasomes
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