Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study

In this work, we propose and analyze a new concept of gamma ray imaging that corresponds to a gamma camera with a mobile collimator, which can be used in vivo, during surgical interventions for oncological patients for localizing regions of interest such as tumors or ganglia. The benefits are a much...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Victor Ilisie [verfasserIn] Laura Moliner [verfasserIn] Constantino Morera [verfasserIn] Johan Nuyts [verfasserIn] José María Benlloch [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	gamma camera SPECT PET mobile collimator pinhole collimator

Übergeordnetes Werk:	In: Sensors - MDPI AG, 2003, 21(2021), 10, p 3367
Übergeordnetes Werk:	volume:21 ; year:2021 ; number:10, p 3367

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/s21103367

Katalog-ID:	DOAJ085523658

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allfieldsSound	10.3390/s21103367 doi (DE-627)DOAJ085523658 (DE-599)DOAJ1ec1b9d527de4e3ebbc1b29f36d112bd DE-627 ger DE-627 rakwb eng TP1-1185 Victor Ilisie verfasserin aut Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In this work, we propose and analyze a new concept of gamma ray imaging that corresponds to a gamma camera with a mobile collimator, which can be used in vivo, during surgical interventions for oncological patients for localizing regions of interest such as tumors or ganglia. The benefits are a much higher sensitivity, better image quality and, consequently, a dose reduction for the patient and medical staff. This novel approach is a practical solution to the overlapping problem which is inherent to multi-pinhole gamma camera imaging and single photon emission computed tomography and which translates into artifacts and/or image truncation in the final reconstructed image. The key concept consists in introducing a relative motion between the collimator and the detector. Moreover, this design could also be incorporated into most commercially available gamma camera devices, without any excessive additional requirements. We use Monte Carlo simulations to assess the feasibility of such a device, analyze three possible designs and compare their sensitivity, resolution and uniformity. We propose a final design of a gamma camera with a high sensitivity ranging from 0.001 to 0.006 cps/Bq, and a high resolution of 0.5–1.0 cm (FWHM), for source-to-detector distances of 4–10 cm. Additionally, this planar gamma camera provides information about the depth of source (with approximate resolution of 1.5 cm) and excellent image uniformity. gamma camera SPECT PET mobile collimator pinhole collimator Chemical technology Laura Moliner verfasserin aut Constantino Morera verfasserin aut Johan Nuyts verfasserin aut José María Benlloch verfasserin aut In Sensors MDPI AG, 2003 21(2021), 10, p 3367 (DE-627)331640910 (DE-600)2052857-7 14248220 nnns volume:21 year:2021 number:10, p 3367 https://doi.org/10.3390/s21103367 kostenfrei https://doaj.org/article/1ec1b9d527de4e3ebbc1b29f36d112bd kostenfrei https://www.mdpi.com/1424-8220/21/10/3367 kostenfrei https://doaj.org/toc/1424-8220 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2057 GBV_ILN_2111 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2021 10, p 3367
language	English
source	In Sensors 21(2021), 10, p 3367 volume:21 year:2021 number:10, p 3367
sourceStr	In Sensors 21(2021), 10, p 3367 volume:21 year:2021 number:10, p 3367
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	gamma camera SPECT PET mobile collimator pinhole collimator Chemical technology
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authorswithroles_txt_mv	Victor Ilisie @@aut@@ Laura Moliner @@aut@@ Constantino Morera @@aut@@ Johan Nuyts @@aut@@ José María Benlloch @@aut@@
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callnumber-first	T - Technology
author	Victor Ilisie
spellingShingle	Victor Ilisie misc TP1-1185 misc gamma camera misc SPECT misc PET misc mobile collimator misc pinhole collimator misc Chemical technology Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study
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topic_title	TP1-1185 Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study gamma camera SPECT PET mobile collimator pinhole collimator
topic	misc TP1-1185 misc gamma camera misc SPECT misc PET misc mobile collimator misc pinhole collimator misc Chemical technology
topic_unstemmed	misc TP1-1185 misc gamma camera misc SPECT misc PET misc mobile collimator misc pinhole collimator misc Chemical technology
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title	Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study
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author_browse	Victor Ilisie Laura Moliner Constantino Morera Johan Nuyts José María Benlloch
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title_sort	gamma camera imaging with rotating multi-pinhole collimator. a monte carlo feasibility study
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title_auth	Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study
abstract	In this work, we propose and analyze a new concept of gamma ray imaging that corresponds to a gamma camera with a mobile collimator, which can be used in vivo, during surgical interventions for oncological patients for localizing regions of interest such as tumors or ganglia. The benefits are a much higher sensitivity, better image quality and, consequently, a dose reduction for the patient and medical staff. This novel approach is a practical solution to the overlapping problem which is inherent to multi-pinhole gamma camera imaging and single photon emission computed tomography and which translates into artifacts and/or image truncation in the final reconstructed image. The key concept consists in introducing a relative motion between the collimator and the detector. Moreover, this design could also be incorporated into most commercially available gamma camera devices, without any excessive additional requirements. We use Monte Carlo simulations to assess the feasibility of such a device, analyze three possible designs and compare their sensitivity, resolution and uniformity. We propose a final design of a gamma camera with a high sensitivity ranging from 0.001 to 0.006 cps/Bq, and a high resolution of 0.5–1.0 cm (FWHM), for source-to-detector distances of 4–10 cm. Additionally, this planar gamma camera provides information about the depth of source (with approximate resolution of 1.5 cm) and excellent image uniformity.
abstractGer	In this work, we propose and analyze a new concept of gamma ray imaging that corresponds to a gamma camera with a mobile collimator, which can be used in vivo, during surgical interventions for oncological patients for localizing regions of interest such as tumors or ganglia. The benefits are a much higher sensitivity, better image quality and, consequently, a dose reduction for the patient and medical staff. This novel approach is a practical solution to the overlapping problem which is inherent to multi-pinhole gamma camera imaging and single photon emission computed tomography and which translates into artifacts and/or image truncation in the final reconstructed image. The key concept consists in introducing a relative motion between the collimator and the detector. Moreover, this design could also be incorporated into most commercially available gamma camera devices, without any excessive additional requirements. We use Monte Carlo simulations to assess the feasibility of such a device, analyze three possible designs and compare their sensitivity, resolution and uniformity. We propose a final design of a gamma camera with a high sensitivity ranging from 0.001 to 0.006 cps/Bq, and a high resolution of 0.5–1.0 cm (FWHM), for source-to-detector distances of 4–10 cm. Additionally, this planar gamma camera provides information about the depth of source (with approximate resolution of 1.5 cm) and excellent image uniformity.
abstract_unstemmed	In this work, we propose and analyze a new concept of gamma ray imaging that corresponds to a gamma camera with a mobile collimator, which can be used in vivo, during surgical interventions for oncological patients for localizing regions of interest such as tumors or ganglia. The benefits are a much higher sensitivity, better image quality and, consequently, a dose reduction for the patient and medical staff. This novel approach is a practical solution to the overlapping problem which is inherent to multi-pinhole gamma camera imaging and single photon emission computed tomography and which translates into artifacts and/or image truncation in the final reconstructed image. The key concept consists in introducing a relative motion between the collimator and the detector. Moreover, this design could also be incorporated into most commercially available gamma camera devices, without any excessive additional requirements. We use Monte Carlo simulations to assess the feasibility of such a device, analyze three possible designs and compare their sensitivity, resolution and uniformity. We propose a final design of a gamma camera with a high sensitivity ranging from 0.001 to 0.006 cps/Bq, and a high resolution of 0.5–1.0 cm (FWHM), for source-to-detector distances of 4–10 cm. Additionally, this planar gamma camera provides information about the depth of source (with approximate resolution of 1.5 cm) and excellent image uniformity.
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title_short	Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study
url	https://doi.org/10.3390/s21103367 https://doaj.org/article/1ec1b9d527de4e3ebbc1b29f36d112bd https://www.mdpi.com/1424-8220/21/10/3367 https://doaj.org/toc/1424-8220
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up_date	2024-07-03T15:15:24.226Z
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Gamma Camera Imaging with Rotating Multi-Pinhole Collimator. A Monte Carlo Feasibility Study

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