Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool

Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate...
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Autor*in:	Massimiliano Leigheb [verfasserIn] Alessandro de Sire [verfasserIn] Matteo Colangelo [verfasserIn] Domenico Zagaria [verfasserIn] Federico Alberto Grassi [verfasserIn] Ottavio Rena [verfasserIn] Patrizio Conte [verfasserIn] Pierluigi Neri [verfasserIn] Alessandro Carriero [verfasserIn] Gian Mauro Sacchetti [verfasserIn] Fabio Penna [verfasserIn] Giuseppina Caretti [verfasserIn] Elisabetta Ferraro [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	sarcopenia ultrasonography muscle muscle thickness muscle stiffness

Übergeordnetes Werk:	In: Diagnostics - MDPI AG, 2012, 11(2021), 11, p 2158
Übergeordnetes Werk:	volume:11 ; year:2021 ; number:11, p 2158

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/diagnostics11112158

Katalog-ID:	DOAJ085573639

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520			\|a Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia.
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allfields	10.3390/diagnostics11112158 doi (DE-627)DOAJ085573639 (DE-599)DOAJ001ae096e7824884835b0f699ea67503 DE-627 ger DE-627 rakwb eng R5-920 Massimiliano Leigheb verfasserin aut Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia. sarcopenia ultrasonography muscle muscle thickness muscle stiffness Medicine (General) Alessandro de Sire verfasserin aut Matteo Colangelo verfasserin aut Domenico Zagaria verfasserin aut Federico Alberto Grassi verfasserin aut Ottavio Rena verfasserin aut Patrizio Conte verfasserin aut Pierluigi Neri verfasserin aut Alessandro Carriero verfasserin aut Gian Mauro Sacchetti verfasserin aut Fabio Penna verfasserin aut Giuseppina Caretti verfasserin aut Elisabetta Ferraro verfasserin aut In Diagnostics MDPI AG, 2012 11(2021), 11, p 2158 (DE-627)718627814 (DE-600)2662336-5 20754418 nnns volume:11 year:2021 number:11, p 2158 https://doi.org/10.3390/diagnostics11112158 kostenfrei https://doaj.org/article/001ae096e7824884835b0f699ea67503 kostenfrei https://www.mdpi.com/2075-4418/11/11/2158 kostenfrei https://doaj.org/toc/2075-4418 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 11, p 2158
spelling	10.3390/diagnostics11112158 doi (DE-627)DOAJ085573639 (DE-599)DOAJ001ae096e7824884835b0f699ea67503 DE-627 ger DE-627 rakwb eng R5-920 Massimiliano Leigheb verfasserin aut Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia. sarcopenia ultrasonography muscle muscle thickness muscle stiffness Medicine (General) Alessandro de Sire verfasserin aut Matteo Colangelo verfasserin aut Domenico Zagaria verfasserin aut Federico Alberto Grassi verfasserin aut Ottavio Rena verfasserin aut Patrizio Conte verfasserin aut Pierluigi Neri verfasserin aut Alessandro Carriero verfasserin aut Gian Mauro Sacchetti verfasserin aut Fabio Penna verfasserin aut Giuseppina Caretti verfasserin aut Elisabetta Ferraro verfasserin aut In Diagnostics MDPI AG, 2012 11(2021), 11, p 2158 (DE-627)718627814 (DE-600)2662336-5 20754418 nnns volume:11 year:2021 number:11, p 2158 https://doi.org/10.3390/diagnostics11112158 kostenfrei https://doaj.org/article/001ae096e7824884835b0f699ea67503 kostenfrei https://www.mdpi.com/2075-4418/11/11/2158 kostenfrei https://doaj.org/toc/2075-4418 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 11, p 2158
allfields_unstemmed	10.3390/diagnostics11112158 doi (DE-627)DOAJ085573639 (DE-599)DOAJ001ae096e7824884835b0f699ea67503 DE-627 ger DE-627 rakwb eng R5-920 Massimiliano Leigheb verfasserin aut Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia. sarcopenia ultrasonography muscle muscle thickness muscle stiffness Medicine (General) Alessandro de Sire verfasserin aut Matteo Colangelo verfasserin aut Domenico Zagaria verfasserin aut Federico Alberto Grassi verfasserin aut Ottavio Rena verfasserin aut Patrizio Conte verfasserin aut Pierluigi Neri verfasserin aut Alessandro Carriero verfasserin aut Gian Mauro Sacchetti verfasserin aut Fabio Penna verfasserin aut Giuseppina Caretti verfasserin aut Elisabetta Ferraro verfasserin aut In Diagnostics MDPI AG, 2012 11(2021), 11, p 2158 (DE-627)718627814 (DE-600)2662336-5 20754418 nnns volume:11 year:2021 number:11, p 2158 https://doi.org/10.3390/diagnostics11112158 kostenfrei https://doaj.org/article/001ae096e7824884835b0f699ea67503 kostenfrei https://www.mdpi.com/2075-4418/11/11/2158 kostenfrei https://doaj.org/toc/2075-4418 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 11, p 2158
allfieldsGer	10.3390/diagnostics11112158 doi (DE-627)DOAJ085573639 (DE-599)DOAJ001ae096e7824884835b0f699ea67503 DE-627 ger DE-627 rakwb eng R5-920 Massimiliano Leigheb verfasserin aut Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia. sarcopenia ultrasonography muscle muscle thickness muscle stiffness Medicine (General) Alessandro de Sire verfasserin aut Matteo Colangelo verfasserin aut Domenico Zagaria verfasserin aut Federico Alberto Grassi verfasserin aut Ottavio Rena verfasserin aut Patrizio Conte verfasserin aut Pierluigi Neri verfasserin aut Alessandro Carriero verfasserin aut Gian Mauro Sacchetti verfasserin aut Fabio Penna verfasserin aut Giuseppina Caretti verfasserin aut Elisabetta Ferraro verfasserin aut In Diagnostics MDPI AG, 2012 11(2021), 11, p 2158 (DE-627)718627814 (DE-600)2662336-5 20754418 nnns volume:11 year:2021 number:11, p 2158 https://doi.org/10.3390/diagnostics11112158 kostenfrei https://doaj.org/article/001ae096e7824884835b0f699ea67503 kostenfrei https://www.mdpi.com/2075-4418/11/11/2158 kostenfrei https://doaj.org/toc/2075-4418 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 11, p 2158
allfieldsSound	10.3390/diagnostics11112158 doi (DE-627)DOAJ085573639 (DE-599)DOAJ001ae096e7824884835b0f699ea67503 DE-627 ger DE-627 rakwb eng R5-920 Massimiliano Leigheb verfasserin aut Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia. sarcopenia ultrasonography muscle muscle thickness muscle stiffness Medicine (General) Alessandro de Sire verfasserin aut Matteo Colangelo verfasserin aut Domenico Zagaria verfasserin aut Federico Alberto Grassi verfasserin aut Ottavio Rena verfasserin aut Patrizio Conte verfasserin aut Pierluigi Neri verfasserin aut Alessandro Carriero verfasserin aut Gian Mauro Sacchetti verfasserin aut Fabio Penna verfasserin aut Giuseppina Caretti verfasserin aut Elisabetta Ferraro verfasserin aut In Diagnostics MDPI AG, 2012 11(2021), 11, p 2158 (DE-627)718627814 (DE-600)2662336-5 20754418 nnns volume:11 year:2021 number:11, p 2158 https://doi.org/10.3390/diagnostics11112158 kostenfrei https://doaj.org/article/001ae096e7824884835b0f699ea67503 kostenfrei https://www.mdpi.com/2075-4418/11/11/2158 kostenfrei https://doaj.org/toc/2075-4418 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2021 11, p 2158
language	English
source	In Diagnostics 11(2021), 11, p 2158 volume:11 year:2021 number:11, p 2158
sourceStr	In Diagnostics 11(2021), 11, p 2158 volume:11 year:2021 number:11, p 2158
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	sarcopenia ultrasonography muscle muscle thickness muscle stiffness Medicine (General)
isfreeaccess_bool	true
container_title	Diagnostics
authorswithroles_txt_mv	Massimiliano Leigheb @@aut@@ Alessandro de Sire @@aut@@ Matteo Colangelo @@aut@@ Domenico Zagaria @@aut@@ Federico Alberto Grassi @@aut@@ Ottavio Rena @@aut@@ Patrizio Conte @@aut@@ Pierluigi Neri @@aut@@ Alessandro Carriero @@aut@@ Gian Mauro Sacchetti @@aut@@ Fabio Penna @@aut@@ Giuseppina Caretti @@aut@@ Elisabetta Ferraro @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	718627814
id	DOAJ085573639
language_de	englisch
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callnumber-first	R - Medicine
author	Massimiliano Leigheb
spellingShingle	Massimiliano Leigheb misc R5-920 misc sarcopenia misc ultrasonography misc muscle misc muscle thickness misc muscle stiffness misc Medicine (General) Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool
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topic_title	R5-920 Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool sarcopenia ultrasonography muscle muscle thickness muscle stiffness
topic	misc R5-920 misc sarcopenia misc ultrasonography misc muscle misc muscle thickness misc muscle stiffness misc Medicine (General)
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title	Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool
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title_full	Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool
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author_browse	Massimiliano Leigheb Alessandro de Sire Matteo Colangelo Domenico Zagaria Federico Alberto Grassi Ottavio Rena Patrizio Conte Pierluigi Neri Alessandro Carriero Gian Mauro Sacchetti Fabio Penna Giuseppina Caretti Elisabetta Ferraro
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title_sort	sarcopenia diagnosis: reliability of the ultrasound assessment of the tibialis anterior muscle as an alternative evaluation tool
callnumber	R5-920
title_auth	Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool
abstract	Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia.
abstractGer	Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia.
abstract_unstemmed	Sarcopenia is a skeletal muscle disorder characterized by reduced muscle mass, strength, and performance. Muscle ultrasound can be helpful in assessing muscle mass, quality, and architecture, and thus possibly useful for diagnosing or screening sarcopenia. The objective of this study was to evaluate the reliability of ultrasound assessment of tibialis anterior muscle in sarcopenia diagnosis. We included subjects undergoing total or partial hip replacement, comparing measures with a healthy control group. We measured the following parameters: tibialis anterior muscle thickness, echogenicity, architecture, stiffness, skeletal muscle index (SMI), hand grip strength, and sarcopenia related quality of life evaluated through the SarQoL questionnaire. We included 33 participants with a mean age of 54.97 ± 23.91 years. In the study group we found reduced tibialis anterior muscle thickness compared to the healthy control group (19.49 ± 4.92 vs. 28.94 ± 3.63 mm, <i<p</i< < 0.05) with significant correlation with SarQoL values (r = 0.80, <i<p</i< < 0.05), dynamometer hand strength (r = 0.72, <i<p</i< < 0.05) and SMI (r = 0.76, <i<p</i< < 0.05). Moreover, we found reduced stiffness (32.21 ± 12.31 vs. 27.07 ± 8.04 Kpa, <i<p</i< < 0.05). AUC measures of ROC curves were 0.89 predicting reduced muscle strength, and 0.97 predicting reduced SMI for tibialis anterior muscle thickness, while they were 0.73 and 0.85, respectively, for muscle stiffness. Our findings showed that ultrasound assessment of tibialis anterior muscle might be considered a reliable measurement tool to evaluate sarcopenia.
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title_short	Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool
url	https://doi.org/10.3390/diagnostics11112158 https://doaj.org/article/001ae096e7824884835b0f699ea67503 https://www.mdpi.com/2075-4418/11/11/2158 https://doaj.org/toc/2075-4418
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up_date	2024-07-03T15:34:15.010Z
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Sarcopenia Diagnosis: Reliability of the Ultrasound Assessment of the Tibialis Anterior Muscle as an Alternative Evaluation Tool

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