Study of salivary IgA concentrations, salivary flow rate in patients with β –thalassemia major in Missan Governorate
Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to eval...
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Gespeichert in:
| Autor*in: |
Jamal M Diwan [verfasserIn] Zaheda J Mohammad [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2015 |
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| Übergeordnetes Werk: |
In: Journal of Baghdad College of Dentistry - College of Dentistry/ University of Baghdad, 2021, 27(2015), 3 |
|---|---|
| Übergeordnetes Werk: |
volume:27 ; year:2015 ; number:3 |
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| 520 | |a Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. | ||
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(DE-627)DOAJ085810274 (DE-599)DOAJ0e7d1dc09daf4b96a9e82292eae962ee DE-627 ger DE-627 rakwb eng RK1-715 Jamal M Diwan verfasserin aut Study of salivary IgA concentrations, salivary flow rate in patients with β –thalassemia major in Missan Governorate 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. Dentistry Zaheda J Mohammad verfasserin aut In Journal of Baghdad College of Dentistry College of Dentistry/ University of Baghdad, 2021 27(2015), 3 (DE-627)DOAJ078612241 23115270 nnns volume:27 year:2015 number:3 https://doaj.org/article/0e7d1dc09daf4b96a9e82292eae962ee kostenfrei https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/806 kostenfrei https://doaj.org/toc/2311-5270 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 27 2015 3 |
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(DE-627)DOAJ085810274 (DE-599)DOAJ0e7d1dc09daf4b96a9e82292eae962ee DE-627 ger DE-627 rakwb eng RK1-715 Jamal M Diwan verfasserin aut Study of salivary IgA concentrations, salivary flow rate in patients with β –thalassemia major in Missan Governorate 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. Dentistry Zaheda J Mohammad verfasserin aut In Journal of Baghdad College of Dentistry College of Dentistry/ University of Baghdad, 2021 27(2015), 3 (DE-627)DOAJ078612241 23115270 nnns volume:27 year:2015 number:3 https://doaj.org/article/0e7d1dc09daf4b96a9e82292eae962ee kostenfrei https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/806 kostenfrei https://doaj.org/toc/2311-5270 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 27 2015 3 |
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(DE-627)DOAJ085810274 (DE-599)DOAJ0e7d1dc09daf4b96a9e82292eae962ee DE-627 ger DE-627 rakwb eng RK1-715 Jamal M Diwan verfasserin aut Study of salivary IgA concentrations, salivary flow rate in patients with β –thalassemia major in Missan Governorate 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. Dentistry Zaheda J Mohammad verfasserin aut In Journal of Baghdad College of Dentistry College of Dentistry/ University of Baghdad, 2021 27(2015), 3 (DE-627)DOAJ078612241 23115270 nnns volume:27 year:2015 number:3 https://doaj.org/article/0e7d1dc09daf4b96a9e82292eae962ee kostenfrei https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/806 kostenfrei https://doaj.org/toc/2311-5270 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 27 2015 3 |
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(DE-627)DOAJ085810274 (DE-599)DOAJ0e7d1dc09daf4b96a9e82292eae962ee DE-627 ger DE-627 rakwb eng RK1-715 Jamal M Diwan verfasserin aut Study of salivary IgA concentrations, salivary flow rate in patients with β –thalassemia major in Missan Governorate 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. Dentistry Zaheda J Mohammad verfasserin aut In Journal of Baghdad College of Dentistry College of Dentistry/ University of Baghdad, 2021 27(2015), 3 (DE-627)DOAJ078612241 23115270 nnns volume:27 year:2015 number:3 https://doaj.org/article/0e7d1dc09daf4b96a9e82292eae962ee kostenfrei https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/806 kostenfrei https://doaj.org/toc/2311-5270 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 27 2015 3 |
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(DE-627)DOAJ085810274 (DE-599)DOAJ0e7d1dc09daf4b96a9e82292eae962ee DE-627 ger DE-627 rakwb eng RK1-715 Jamal M Diwan verfasserin aut Study of salivary IgA concentrations, salivary flow rate in patients with β –thalassemia major in Missan Governorate 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. Dentistry Zaheda J Mohammad verfasserin aut In Journal of Baghdad College of Dentistry College of Dentistry/ University of Baghdad, 2021 27(2015), 3 (DE-627)DOAJ078612241 23115270 nnns volume:27 year:2015 number:3 https://doaj.org/article/0e7d1dc09daf4b96a9e82292eae962ee kostenfrei https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/806 kostenfrei https://doaj.org/toc/2311-5270 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 27 2015 3 |
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Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. |
| abstractGer |
Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. |
| abstract_unstemmed |
Background: Beta-thalassemia major is the most common monogenic known disorder in the Middle East, characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic Individuals. This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). Conclusions: Beta-thalassemia major affects salivary flow rate and SIgA concentration. |
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Study of salivary IgA concentrations, salivary flow rate in patients with β –thalassemia major in Missan Governorate |
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https://doaj.org/article/0e7d1dc09daf4b96a9e82292eae962ee https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/806 https://doaj.org/toc/2311-5270 |
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true |
| author2 |
Zaheda J Mohammad |
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Zaheda J Mohammad |
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DOAJ078612241 |
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RK - Dentistry |
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c |
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true |
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false |
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RK1-715 |
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2024-07-03T16:59:32.316Z |
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1803577953948270592 |
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This study aimed to evaluate salivary flow rate and salivary IgA in β-thalassemia major patients. Since many oral and systemic conditions manifest themselves as changes in the flow and composition of saliva the dental practitioner is advised to remain up-to-date with this issue. Materials and methods: The study samples consist of (60) subjects, patients group composed of (30) patients with β –thalassemia major, age rang (5-23) years and (30) healthy locking subject of both sexes as control group, with age range from (5-25) years. Results: Most patients were in the first and second decade of life (90%) this indicate a reduced life expectancy in those patients, laboratory investigations for salivary IgA concentrations revealed a significant increase in means of this marker in compare with control group and this difference is statistically significant, (p= 0.05) at P value ≤ 0.05.Regarding the salivary flow rate there was a statistically significant decrease in mean of salivary flow rate in patients group as compared with control group (P= 0.013). 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7.399867 |