Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease

Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (HY) stages IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily lif...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Kristina Rosqvist [verfasserIn] Anette Schrag [verfasserIn] Per Odin [verfasserIn] the CLaSP Consortium [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Parkinson’s disease late stage informal caregiver caregiver burden

Übergeordnetes Werk:	In: Brain Sciences - MDPI AG, 2012, 12(2022), 1, p 111
Übergeordnetes Werk:	volume:12 ; year:2022 ; number:1, p 111

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/brainsci12010111

Katalog-ID:	DOAJ086002600

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author	Kristina Rosqvist
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topic_title	RC321-571 Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease Parkinson’s disease late stage informal caregiver caregiver burden
topic	misc RC321-571 misc Parkinson’s disease misc late stage misc informal caregiver misc caregiver burden misc Neurosciences. Biological psychiatry. Neuropsychiatry
topic_unstemmed	misc RC321-571 misc Parkinson’s disease misc late stage misc informal caregiver misc caregiver burden misc Neurosciences. Biological psychiatry. Neuropsychiatry
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title	Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
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title_full	Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
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title_sort	caregiver burden and quality of life in late stage parkinson’s disease
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title_auth	Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
abstract	Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (HY) stages IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily life, resulting in an increased burden for the informal caregivers. To assess the implications of the caregiver burden, caregiver quality of life (QoL) was assessed in 74 informal caregivers to patients in late stage PD, by the Alzheimer’s Patient Partners Life Impact Questionnaire (APPLIQue), which has been found useful also in PD. The majority of caregivers were the spouse/partner. Individual items provided information on which aspects of caregiver burden were the most common, i.e., items: “feel guilty if not there” (71% affirmed), “situation wears me down” (65% affirmed) and “always on my mind” (61% affirmed). In simple linear regression analyses, female patient gender (<i<p</i< = 0.007), better cognition (<i<p</i< = 0.004), lower NMS burden (<i<p</i< = 0.012) and not being the partner (<i<p</i< = 0.022) were associated with better caregiver QoL. Multivariable linear regression analyses identified better cognition (<i<p</i< = 0.004) and female patient gender (<i<p</i< = 0.035) as independently associated with better informal caregiver QoL. Identifying and treating NMS as well as recognizing and alleviating caregiver burden seem essential to enhance QoL for both patients and caregivers in late stage PD.
abstractGer	Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (HY) stages IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily life, resulting in an increased burden for the informal caregivers. To assess the implications of the caregiver burden, caregiver quality of life (QoL) was assessed in 74 informal caregivers to patients in late stage PD, by the Alzheimer’s Patient Partners Life Impact Questionnaire (APPLIQue), which has been found useful also in PD. The majority of caregivers were the spouse/partner. Individual items provided information on which aspects of caregiver burden were the most common, i.e., items: “feel guilty if not there” (71% affirmed), “situation wears me down” (65% affirmed) and “always on my mind” (61% affirmed). In simple linear regression analyses, female patient gender (<i<p</i< = 0.007), better cognition (<i<p</i< = 0.004), lower NMS burden (<i<p</i< = 0.012) and not being the partner (<i<p</i< = 0.022) were associated with better caregiver QoL. Multivariable linear regression analyses identified better cognition (<i<p</i< = 0.004) and female patient gender (<i<p</i< = 0.035) as independently associated with better informal caregiver QoL. Identifying and treating NMS as well as recognizing and alleviating caregiver burden seem essential to enhance QoL for both patients and caregivers in late stage PD.
abstract_unstemmed	Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (HY) stages IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily life, resulting in an increased burden for the informal caregivers. To assess the implications of the caregiver burden, caregiver quality of life (QoL) was assessed in 74 informal caregivers to patients in late stage PD, by the Alzheimer’s Patient Partners Life Impact Questionnaire (APPLIQue), which has been found useful also in PD. The majority of caregivers were the spouse/partner. Individual items provided information on which aspects of caregiver burden were the most common, i.e., items: “feel guilty if not there” (71% affirmed), “situation wears me down” (65% affirmed) and “always on my mind” (61% affirmed). In simple linear regression analyses, female patient gender (<i<p</i< = 0.007), better cognition (<i<p</i< = 0.004), lower NMS burden (<i<p</i< = 0.012) and not being the partner (<i<p</i< = 0.022) were associated with better caregiver QoL. Multivariable linear regression analyses identified better cognition (<i<p</i< = 0.004) and female patient gender (<i<p</i< = 0.035) as independently associated with better informal caregiver QoL. Identifying and treating NMS as well as recognizing and alleviating caregiver burden seem essential to enhance QoL for both patients and caregivers in late stage PD.
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title_short	Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
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Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease

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