The syndromic triad of COVID-19, type 2 diabetes, and malnutrition

The coronavirus disease 2019 (COVID-19) pandemic challenges our collective understanding of transmission, prevention, complications, and clinical management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Risk factors for severe infection, morbidity, and mortality are asso...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Jeffrey I. Mechanick [verfasserIn] Elena A. Christofides [verfasserIn] Albert E. Marchetti [verfasserIn] Kristin K. Hoddy [verfasserIn] Jim Joachim [verfasserIn] Refaat Hegazi [verfasserIn] Osama Hamdy [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	cardiometabolic cardiometabolic-based chronic disease coronavirus COVID-19 COVID-related cardiometabolic syndrome malnutrition

Übergeordnetes Werk:	In: Frontiers in Nutrition - Frontiers Media S.A., 2014, 10(2023)
Übergeordnetes Werk:	volume:10 ; year:2023

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fnut.2023.1122203

Katalog-ID:	DOAJ086260022

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allfieldsSound	10.3389/fnut.2023.1122203 doi (DE-627)DOAJ086260022 (DE-599)DOAJ19ba59323d854cd4b281adbfa584fa96 DE-627 ger DE-627 rakwb eng TX341-641 Jeffrey I. Mechanick verfasserin aut The syndromic triad of COVID-19, type 2 diabetes, and malnutrition 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The coronavirus disease 2019 (COVID-19) pandemic challenges our collective understanding of transmission, prevention, complications, and clinical management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Risk factors for severe infection, morbidity, and mortality are associated with age, environment, socioeconomic status, comorbidities, and interventional timing. Clinical investigations report an intriguing association of COVID-19 with diabetes mellitus and malnutrition but incompletely describe the triphasic relationship, its mechanistic pathways, and potential therapeutic approaches to address each malady and their underlying metabolic disorders. This narrative review highlights common chronic disease states that interact epidemiologically and mechanistically with the COVID-19 to create a syndromic phenotype—the COVID-Related Cardiometabolic Syndrome—linking cardiometabolic-based chronic disease drivers with pre-, acute, and chronic/post-COVID-19 disease stages. Since the association of nutritional disorders with COVID-19 and cardiometabolic risk factors is well established, a syndromic triad of COVID-19, type 2 diabetes, and malnutrition is hypothesized that can direct, inform, and optimize care. In this review, each of the three edges of this network is uniquely summarized, nutritional therapies discussed, and a structure for early preventive care proposed. Concerted efforts to identify malnutrition in patients with COVID-19 and elevated metabolic risks are needed and can be followed by improved dietary management while simultaneously addressing dysglycemia-based chronic disease and malnutrition-based chronic disease. cardiometabolic cardiometabolic-based chronic disease coronavirus COVID-19 COVID-related cardiometabolic syndrome malnutrition Nutrition. Foods and food supply Jeffrey I. Mechanick verfasserin aut Elena A. Christofides verfasserin aut Albert E. Marchetti verfasserin aut Albert E. Marchetti verfasserin aut Kristin K. Hoddy verfasserin aut Jim Joachim verfasserin aut Refaat Hegazi verfasserin aut Osama Hamdy verfasserin aut Osama Hamdy verfasserin aut In Frontiers in Nutrition Frontiers Media S.A., 2014 10(2023) (DE-627)790231158 (DE-600)2776676-7 2296861X nnns volume:10 year:2023 https://doi.org/10.3389/fnut.2023.1122203 kostenfrei https://doaj.org/article/19ba59323d854cd4b281adbfa584fa96 kostenfrei https://www.frontiersin.org/articles/10.3389/fnut.2023.1122203/full kostenfrei https://doaj.org/toc/2296-861X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4367 GBV_ILN_4700 AR 10 2023
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callnumber-first	T - Technology
author	Jeffrey I. Mechanick
spellingShingle	Jeffrey I. Mechanick misc TX341-641 misc cardiometabolic misc cardiometabolic-based chronic disease misc coronavirus misc COVID-19 misc COVID-related cardiometabolic syndrome misc malnutrition misc Nutrition. Foods and food supply The syndromic triad of COVID-19, type 2 diabetes, and malnutrition
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topic_title	TX341-641 The syndromic triad of COVID-19, type 2 diabetes, and malnutrition cardiometabolic cardiometabolic-based chronic disease coronavirus COVID-19 COVID-related cardiometabolic syndrome malnutrition
topic	misc TX341-641 misc cardiometabolic misc cardiometabolic-based chronic disease misc coronavirus misc COVID-19 misc COVID-related cardiometabolic syndrome misc malnutrition misc Nutrition. Foods and food supply
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title	The syndromic triad of COVID-19, type 2 diabetes, and malnutrition
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title_sort	syndromic triad of covid-19, type 2 diabetes, and malnutrition
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title_auth	The syndromic triad of COVID-19, type 2 diabetes, and malnutrition
abstract	The coronavirus disease 2019 (COVID-19) pandemic challenges our collective understanding of transmission, prevention, complications, and clinical management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Risk factors for severe infection, morbidity, and mortality are associated with age, environment, socioeconomic status, comorbidities, and interventional timing. Clinical investigations report an intriguing association of COVID-19 with diabetes mellitus and malnutrition but incompletely describe the triphasic relationship, its mechanistic pathways, and potential therapeutic approaches to address each malady and their underlying metabolic disorders. This narrative review highlights common chronic disease states that interact epidemiologically and mechanistically with the COVID-19 to create a syndromic phenotype—the COVID-Related Cardiometabolic Syndrome—linking cardiometabolic-based chronic disease drivers with pre-, acute, and chronic/post-COVID-19 disease stages. Since the association of nutritional disorders with COVID-19 and cardiometabolic risk factors is well established, a syndromic triad of COVID-19, type 2 diabetes, and malnutrition is hypothesized that can direct, inform, and optimize care. In this review, each of the three edges of this network is uniquely summarized, nutritional therapies discussed, and a structure for early preventive care proposed. Concerted efforts to identify malnutrition in patients with COVID-19 and elevated metabolic risks are needed and can be followed by improved dietary management while simultaneously addressing dysglycemia-based chronic disease and malnutrition-based chronic disease.
abstractGer	The coronavirus disease 2019 (COVID-19) pandemic challenges our collective understanding of transmission, prevention, complications, and clinical management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Risk factors for severe infection, morbidity, and mortality are associated with age, environment, socioeconomic status, comorbidities, and interventional timing. Clinical investigations report an intriguing association of COVID-19 with diabetes mellitus and malnutrition but incompletely describe the triphasic relationship, its mechanistic pathways, and potential therapeutic approaches to address each malady and their underlying metabolic disorders. This narrative review highlights common chronic disease states that interact epidemiologically and mechanistically with the COVID-19 to create a syndromic phenotype—the COVID-Related Cardiometabolic Syndrome—linking cardiometabolic-based chronic disease drivers with pre-, acute, and chronic/post-COVID-19 disease stages. Since the association of nutritional disorders with COVID-19 and cardiometabolic risk factors is well established, a syndromic triad of COVID-19, type 2 diabetes, and malnutrition is hypothesized that can direct, inform, and optimize care. In this review, each of the three edges of this network is uniquely summarized, nutritional therapies discussed, and a structure for early preventive care proposed. Concerted efforts to identify malnutrition in patients with COVID-19 and elevated metabolic risks are needed and can be followed by improved dietary management while simultaneously addressing dysglycemia-based chronic disease and malnutrition-based chronic disease.
abstract_unstemmed	The coronavirus disease 2019 (COVID-19) pandemic challenges our collective understanding of transmission, prevention, complications, and clinical management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Risk factors for severe infection, morbidity, and mortality are associated with age, environment, socioeconomic status, comorbidities, and interventional timing. Clinical investigations report an intriguing association of COVID-19 with diabetes mellitus and malnutrition but incompletely describe the triphasic relationship, its mechanistic pathways, and potential therapeutic approaches to address each malady and their underlying metabolic disorders. This narrative review highlights common chronic disease states that interact epidemiologically and mechanistically with the COVID-19 to create a syndromic phenotype—the COVID-Related Cardiometabolic Syndrome—linking cardiometabolic-based chronic disease drivers with pre-, acute, and chronic/post-COVID-19 disease stages. Since the association of nutritional disorders with COVID-19 and cardiometabolic risk factors is well established, a syndromic triad of COVID-19, type 2 diabetes, and malnutrition is hypothesized that can direct, inform, and optimize care. In this review, each of the three edges of this network is uniquely summarized, nutritional therapies discussed, and a structure for early preventive care proposed. Concerted efforts to identify malnutrition in patients with COVID-19 and elevated metabolic risks are needed and can be followed by improved dietary management while simultaneously addressing dysglycemia-based chronic disease and malnutrition-based chronic disease.
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title_short	The syndromic triad of COVID-19, type 2 diabetes, and malnutrition
url	https://doi.org/10.3389/fnut.2023.1122203 https://doaj.org/article/19ba59323d854cd4b281adbfa584fa96 https://www.frontiersin.org/articles/10.3389/fnut.2023.1122203/full https://doaj.org/toc/2296-861X
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up_date	2024-07-03T19:37:14.543Z
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The syndromic triad of COVID-19, type 2 diabetes, and malnutrition

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