Ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment

This paper discusses essential issues related to long-term lithium therapy and presents a case of successful 50-year lithium treatment. Lithium is currently regarded as the drug of choice for preventing manic and depressive recurrences in bipolar disorder. In 1/3 of patients with bipolar disorder, l...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ewa Ferensztajn-Rochowiak [verfasserIn] Maria Chłopocka-Woźniak [verfasserIn] Janusz K. Rybakowski [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch ; Portugiesisch

Erschienen:	2020

Schlagwörter:	Mood disorders bipolar lithium

Übergeordnetes Werk:	In: Brazilian Journal of Psychiatry - Associação Brasileira de Psiquiatria (ABP), 2004, 43(2020), 4, Seite 407-413
Übergeordnetes Werk:	volume:43 ; year:2020 ; number:4 ; pages:407-413

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1590/1516-4446-2020-1111

Katalog-ID:	DOAJ086298704

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language	English Portuguese
source	In Brazilian Journal of Psychiatry 43(2020), 4, Seite 407-413 volume:43 year:2020 number:4 pages:407-413
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callnumber-first	R - Medicine
author	Ewa Ferensztajn-Rochowiak
spellingShingle	Ewa Ferensztajn-Rochowiak misc RC435-571 misc Mood disorders misc bipolar misc lithium misc Psychiatry Ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment
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topic_title	RC435-571 Ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment Mood disorders bipolar lithium
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title	Ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment
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title_sort	ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment
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title_auth	Ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment
abstract	This paper discusses essential issues related to long-term lithium therapy and presents a case of successful 50-year lithium treatment. Lithium is currently regarded as the drug of choice for preventing manic and depressive recurrences in bipolar disorder. In 1/3 of patients with bipolar disorder, long-term monotherapy with lithium can completely prevent recurrences of abnormal mood. Numerous clinical and psychosocial factors associated with a good response to lithium have been described. Lithium is more efficacious than other mood stabilizers, and its long-term treatment significantly exceeds them. Lithium also exerts antisuicidal, immunomodulatory, and neuroprotective effects. The main problems associated with long-term lithium treatment include kidney, thyroid, and probably cognitive issues. In this paper, a case of successful continuous lithium treatment for 50 years in a 79-year-old female patient is presented. In this patient, apart from maintaining a euthymic state, long-term lithium treatment also exerted a favorable effect on general health, especially the elimination of viral and other respiratory infections. It is concluded that ultra-long term lithium therapy can enable good professional and psychosocial functioning for many patients, and the possible somatic side effects are manageable.
abstractGer	This paper discusses essential issues related to long-term lithium therapy and presents a case of successful 50-year lithium treatment. Lithium is currently regarded as the drug of choice for preventing manic and depressive recurrences in bipolar disorder. In 1/3 of patients with bipolar disorder, long-term monotherapy with lithium can completely prevent recurrences of abnormal mood. Numerous clinical and psychosocial factors associated with a good response to lithium have been described. Lithium is more efficacious than other mood stabilizers, and its long-term treatment significantly exceeds them. Lithium also exerts antisuicidal, immunomodulatory, and neuroprotective effects. The main problems associated with long-term lithium treatment include kidney, thyroid, and probably cognitive issues. In this paper, a case of successful continuous lithium treatment for 50 years in a 79-year-old female patient is presented. In this patient, apart from maintaining a euthymic state, long-term lithium treatment also exerted a favorable effect on general health, especially the elimination of viral and other respiratory infections. It is concluded that ultra-long term lithium therapy can enable good professional and psychosocial functioning for many patients, and the possible somatic side effects are manageable.
abstract_unstemmed	This paper discusses essential issues related to long-term lithium therapy and presents a case of successful 50-year lithium treatment. Lithium is currently regarded as the drug of choice for preventing manic and depressive recurrences in bipolar disorder. In 1/3 of patients with bipolar disorder, long-term monotherapy with lithium can completely prevent recurrences of abnormal mood. Numerous clinical and psychosocial factors associated with a good response to lithium have been described. Lithium is more efficacious than other mood stabilizers, and its long-term treatment significantly exceeds them. Lithium also exerts antisuicidal, immunomodulatory, and neuroprotective effects. The main problems associated with long-term lithium treatment include kidney, thyroid, and probably cognitive issues. In this paper, a case of successful continuous lithium treatment for 50 years in a 79-year-old female patient is presented. In this patient, apart from maintaining a euthymic state, long-term lithium treatment also exerted a favorable effect on general health, especially the elimination of viral and other respiratory infections. It is concluded that ultra-long term lithium therapy can enable good professional and psychosocial functioning for many patients, and the possible somatic side effects are manageable.
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title_short	Ultra-long-term lithium therapy: all-important matters and a case of successful 50-year lithium treatment
url	https://doi.org/10.1590/1516-4446-2020-1111 https://doaj.org/article/aa8cf2df9c5b4f1bb2962e1061e9fccb http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462021000400407&tlng=en https://doaj.org/toc/1809-452X
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