Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area

Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Wei-Ru Cho [verfasserIn] Hui-Ling Huang [verfasserIn] Nien-Tzu Hsu [verfasserIn] Tung-Jung Huang [verfasserIn] Te-Sheng Chang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	hepatocellular carcinoma referral screening

Übergeordnetes Werk:	In: Viruses - MDPI AG, 2009, 15(2023), 3, p 786
Übergeordnetes Werk:	volume:15 ; year:2023 ; number:3, p 786

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/v15030786

Katalog-ID:	DOAJ087216167

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allfields	10.3390/v15030786 doi (DE-627)DOAJ087216167 (DE-599)DOAJ57c99adf48dd4f8f82919e4e7d73978d DE-627 ger DE-627 rakwb eng QR1-502 Wei-Ru Cho verfasserin aut Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment. This study enrolled 77 consecutive patients with newly diagnosed HCCs between 2017 and 2022, with a mean age of 65.7 ± 11.1 years. The screening group included HCC patients detected through health checkups, and those detected by routine clinical service served as the control group. Compared to the 24 patients in the control group, the 53 patients in the screening group had more cases with early stage cancer (Barcelona Clinic Liver Cancer or BCLC stage 0 + A 86.8% vs. 62.5%, <i<p</i< = 0.028), better liver reserve (albumin–bilirubin or ALBI grade I 77.3% vs. 50%, <i<p</i< = 0.031) and more prolonged survival (<i<p</i< = 0.036). The median survival rates of the 77 patients were <5 years, 3.3 years, and 0.5 years in the BCLC stages 0 + A, B, and C, respectively, which were above the expectations of the BCLC guideline 2022 for stages 0, A, and B. This study provides a model of HCC screening and referral to high-quality care in remote viral-hepatitis-endemic areas. hepatocellular carcinoma referral screening Microbiology Hui-Ling Huang verfasserin aut Nien-Tzu Hsu verfasserin aut Tung-Jung Huang verfasserin aut Te-Sheng Chang verfasserin aut In Viruses MDPI AG, 2009 15(2023), 3, p 786 (DE-627)609775871 (DE-600)2516098-9 19994915 nnns volume:15 year:2023 number:3, p 786 https://doi.org/10.3390/v15030786 kostenfrei https://doaj.org/article/57c99adf48dd4f8f82919e4e7d73978d kostenfrei https://www.mdpi.com/1999-4915/15/3/786 kostenfrei https://doaj.org/toc/1999-4915 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 3, p 786
spelling	10.3390/v15030786 doi (DE-627)DOAJ087216167 (DE-599)DOAJ57c99adf48dd4f8f82919e4e7d73978d DE-627 ger DE-627 rakwb eng QR1-502 Wei-Ru Cho verfasserin aut Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment. This study enrolled 77 consecutive patients with newly diagnosed HCCs between 2017 and 2022, with a mean age of 65.7 ± 11.1 years. The screening group included HCC patients detected through health checkups, and those detected by routine clinical service served as the control group. Compared to the 24 patients in the control group, the 53 patients in the screening group had more cases with early stage cancer (Barcelona Clinic Liver Cancer or BCLC stage 0 + A 86.8% vs. 62.5%, <i<p</i< = 0.028), better liver reserve (albumin–bilirubin or ALBI grade I 77.3% vs. 50%, <i<p</i< = 0.031) and more prolonged survival (<i<p</i< = 0.036). The median survival rates of the 77 patients were <5 years, 3.3 years, and 0.5 years in the BCLC stages 0 + A, B, and C, respectively, which were above the expectations of the BCLC guideline 2022 for stages 0, A, and B. This study provides a model of HCC screening and referral to high-quality care in remote viral-hepatitis-endemic areas. hepatocellular carcinoma referral screening Microbiology Hui-Ling Huang verfasserin aut Nien-Tzu Hsu verfasserin aut Tung-Jung Huang verfasserin aut Te-Sheng Chang verfasserin aut In Viruses MDPI AG, 2009 15(2023), 3, p 786 (DE-627)609775871 (DE-600)2516098-9 19994915 nnns volume:15 year:2023 number:3, p 786 https://doi.org/10.3390/v15030786 kostenfrei https://doaj.org/article/57c99adf48dd4f8f82919e4e7d73978d kostenfrei https://www.mdpi.com/1999-4915/15/3/786 kostenfrei https://doaj.org/toc/1999-4915 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 3, p 786
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allfieldsGer	10.3390/v15030786 doi (DE-627)DOAJ087216167 (DE-599)DOAJ57c99adf48dd4f8f82919e4e7d73978d DE-627 ger DE-627 rakwb eng QR1-502 Wei-Ru Cho verfasserin aut Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment. This study enrolled 77 consecutive patients with newly diagnosed HCCs between 2017 and 2022, with a mean age of 65.7 ± 11.1 years. The screening group included HCC patients detected through health checkups, and those detected by routine clinical service served as the control group. Compared to the 24 patients in the control group, the 53 patients in the screening group had more cases with early stage cancer (Barcelona Clinic Liver Cancer or BCLC stage 0 + A 86.8% vs. 62.5%, <i<p</i< = 0.028), better liver reserve (albumin–bilirubin or ALBI grade I 77.3% vs. 50%, <i<p</i< = 0.031) and more prolonged survival (<i<p</i< = 0.036). The median survival rates of the 77 patients were <5 years, 3.3 years, and 0.5 years in the BCLC stages 0 + A, B, and C, respectively, which were above the expectations of the BCLC guideline 2022 for stages 0, A, and B. This study provides a model of HCC screening and referral to high-quality care in remote viral-hepatitis-endemic areas. hepatocellular carcinoma referral screening Microbiology Hui-Ling Huang verfasserin aut Nien-Tzu Hsu verfasserin aut Tung-Jung Huang verfasserin aut Te-Sheng Chang verfasserin aut In Viruses MDPI AG, 2009 15(2023), 3, p 786 (DE-627)609775871 (DE-600)2516098-9 19994915 nnns volume:15 year:2023 number:3, p 786 https://doi.org/10.3390/v15030786 kostenfrei https://doaj.org/article/57c99adf48dd4f8f82919e4e7d73978d kostenfrei https://www.mdpi.com/1999-4915/15/3/786 kostenfrei https://doaj.org/toc/1999-4915 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 3, p 786
allfieldsSound	10.3390/v15030786 doi (DE-627)DOAJ087216167 (DE-599)DOAJ57c99adf48dd4f8f82919e4e7d73978d DE-627 ger DE-627 rakwb eng QR1-502 Wei-Ru Cho verfasserin aut Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment. This study enrolled 77 consecutive patients with newly diagnosed HCCs between 2017 and 2022, with a mean age of 65.7 ± 11.1 years. The screening group included HCC patients detected through health checkups, and those detected by routine clinical service served as the control group. Compared to the 24 patients in the control group, the 53 patients in the screening group had more cases with early stage cancer (Barcelona Clinic Liver Cancer or BCLC stage 0 + A 86.8% vs. 62.5%, <i<p</i< = 0.028), better liver reserve (albumin–bilirubin or ALBI grade I 77.3% vs. 50%, <i<p</i< = 0.031) and more prolonged survival (<i<p</i< = 0.036). The median survival rates of the 77 patients were <5 years, 3.3 years, and 0.5 years in the BCLC stages 0 + A, B, and C, respectively, which were above the expectations of the BCLC guideline 2022 for stages 0, A, and B. This study provides a model of HCC screening and referral to high-quality care in remote viral-hepatitis-endemic areas. hepatocellular carcinoma referral screening Microbiology Hui-Ling Huang verfasserin aut Nien-Tzu Hsu verfasserin aut Tung-Jung Huang verfasserin aut Te-Sheng Chang verfasserin aut In Viruses MDPI AG, 2009 15(2023), 3, p 786 (DE-627)609775871 (DE-600)2516098-9 19994915 nnns volume:15 year:2023 number:3, p 786 https://doi.org/10.3390/v15030786 kostenfrei https://doaj.org/article/57c99adf48dd4f8f82919e4e7d73978d kostenfrei https://www.mdpi.com/1999-4915/15/3/786 kostenfrei https://doaj.org/toc/1999-4915 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 3, p 786
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callnumber-first	Q - Science
author	Wei-Ru Cho
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topic_title	QR1-502 Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area hepatocellular carcinoma referral screening
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title	Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area
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title_sort	above-standard survival of hepatocellular carcinoma as the final outcome of comprehensive hepatology care programs in a remote hcv-endemic area
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title_auth	Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area
abstract	Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment. This study enrolled 77 consecutive patients with newly diagnosed HCCs between 2017 and 2022, with a mean age of 65.7 ± 11.1 years. The screening group included HCC patients detected through health checkups, and those detected by routine clinical service served as the control group. Compared to the 24 patients in the control group, the 53 patients in the screening group had more cases with early stage cancer (Barcelona Clinic Liver Cancer or BCLC stage 0 + A 86.8% vs. 62.5%, <i<p</i< = 0.028), better liver reserve (albumin–bilirubin or ALBI grade I 77.3% vs. 50%, <i<p</i< = 0.031) and more prolonged survival (<i<p</i< = 0.036). The median survival rates of the 77 patients were <5 years, 3.3 years, and 0.5 years in the BCLC stages 0 + A, B, and C, respectively, which were above the expectations of the BCLC guideline 2022 for stages 0, A, and B. This study provides a model of HCC screening and referral to high-quality care in remote viral-hepatitis-endemic areas.
abstractGer	Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment. This study enrolled 77 consecutive patients with newly diagnosed HCCs between 2017 and 2022, with a mean age of 65.7 ± 11.1 years. The screening group included HCC patients detected through health checkups, and those detected by routine clinical service served as the control group. Compared to the 24 patients in the control group, the 53 patients in the screening group had more cases with early stage cancer (Barcelona Clinic Liver Cancer or BCLC stage 0 + A 86.8% vs. 62.5%, <i<p</i< = 0.028), better liver reserve (albumin–bilirubin or ALBI grade I 77.3% vs. 50%, <i<p</i< = 0.031) and more prolonged survival (<i<p</i< = 0.036). The median survival rates of the 77 patients were <5 years, 3.3 years, and 0.5 years in the BCLC stages 0 + A, B, and C, respectively, which were above the expectations of the BCLC guideline 2022 for stages 0, A, and B. This study provides a model of HCC screening and referral to high-quality care in remote viral-hepatitis-endemic areas.
abstract_unstemmed	Early detection and prompt linkage to care are critical for hepatocellular carcinoma (HCC) care. Chang Gung Memorial Hospital (CGMH) Yunlin branch, a local hospital in a rural area, undertakes health checkup programs in addition to its routine clinical service. Patients with HCC are referred to CGMH Chiayi branch, a tertiary referral hospital, for treatment. This study enrolled 77 consecutive patients with newly diagnosed HCCs between 2017 and 2022, with a mean age of 65.7 ± 11.1 years. The screening group included HCC patients detected through health checkups, and those detected by routine clinical service served as the control group. Compared to the 24 patients in the control group, the 53 patients in the screening group had more cases with early stage cancer (Barcelona Clinic Liver Cancer or BCLC stage 0 + A 86.8% vs. 62.5%, <i<p</i< = 0.028), better liver reserve (albumin–bilirubin or ALBI grade I 77.3% vs. 50%, <i<p</i< = 0.031) and more prolonged survival (<i<p</i< = 0.036). The median survival rates of the 77 patients were <5 years, 3.3 years, and 0.5 years in the BCLC stages 0 + A, B, and C, respectively, which were above the expectations of the BCLC guideline 2022 for stages 0, A, and B. This study provides a model of HCC screening and referral to high-quality care in remote viral-hepatitis-endemic areas.
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title_short	Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area
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up_date	2024-07-04T00:44:11.824Z
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Above-Standard Survival of Hepatocellular Carcinoma as the Final Outcome of Comprehensive Hepatology Care Programs in a Remote HCV-Endemic Area

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