Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles

Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investiga...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ntombikayise Mahaye [verfasserIn] Ndeke Musee [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll

Übergeordnetes Werk:	In: Toxics - MDPI AG, 2014, 11(2023), 3, p 283
Übergeordnetes Werk:	volume:11 ; year:2023 ; number:3, p 283

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/toxics11030283

Katalog-ID:	DOAJ087224054

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ087224054
003	DE-627
005	20240413043754.0
007	cr uuu---uuuuu
008	230331s2023 xx \|\|\|\|\|o 00\| \|\|eng c
024	7		\|a 10.3390/toxics11030283 \|2 doi
035			\|a (DE-627)DOAJ087224054
035			\|a (DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
050		0	\|a TP1-1185
100	0		\|a Ntombikayise Mahaye \|e verfasserin \|4 aut
245	1	0	\|a Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles
264		1	\|c 2023
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated.
650		4	\|a <i<Pseudokirchneriella subcapitata</i<
650		4	\|a cerium oxide nanoparticles
650		4	\|a DNA stability
650		4	\|a RAPD-PCR
650		4	\|a growth effect
650		4	\|a chlorophyll <i<a</i< content
653		0	\|a Chemical technology
700	0		\|a Ndeke Musee \|e verfasserin \|4 aut
773	0	8	\|i In \|t Toxics \|d MDPI AG, 2014 \|g 11(2023), 3, p 283 \|w (DE-627)768577497 \|w (DE-600)2733883-6 \|x 23056304 \|7 nnns
773	1	8	\|g volume:11 \|g year:2023 \|g number:3, p 283
856	4	0	\|u https://doi.org/10.3390/toxics11030283 \|z kostenfrei
856	4	0	\|u https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867 \|z kostenfrei
856	4	0	\|u https://www.mdpi.com/2305-6304/11/3/283 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/2305-6304 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 11 \|j 2023 \|e 3, p 283

Indexfelder

author_variant	n m nm n m nm
matchkey_str	article:23056304:2023----::vlainfpclnmlclrfetoagepedkrheilaucptt
hierarchy_sort_str	2023
callnumber-subject-code	TP
publishDate	2023
allfields	10.3390/toxics11030283 doi (DE-627)DOAJ087224054 (DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867 DE-627 ger DE-627 rakwb eng TP1-1185 Ntombikayise Mahaye verfasserin aut Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated. <i<Pseudokirchneriella subcapitata</i< cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll <i<a</i< content Chemical technology Ndeke Musee verfasserin aut In Toxics MDPI AG, 2014 11(2023), 3, p 283 (DE-627)768577497 (DE-600)2733883-6 23056304 nnns volume:11 year:2023 number:3, p 283 https://doi.org/10.3390/toxics11030283 kostenfrei https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867 kostenfrei https://www.mdpi.com/2305-6304/11/3/283 kostenfrei https://doaj.org/toc/2305-6304 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 3, p 283
spelling	10.3390/toxics11030283 doi (DE-627)DOAJ087224054 (DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867 DE-627 ger DE-627 rakwb eng TP1-1185 Ntombikayise Mahaye verfasserin aut Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated. <i<Pseudokirchneriella subcapitata</i< cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll <i<a</i< content Chemical technology Ndeke Musee verfasserin aut In Toxics MDPI AG, 2014 11(2023), 3, p 283 (DE-627)768577497 (DE-600)2733883-6 23056304 nnns volume:11 year:2023 number:3, p 283 https://doi.org/10.3390/toxics11030283 kostenfrei https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867 kostenfrei https://www.mdpi.com/2305-6304/11/3/283 kostenfrei https://doaj.org/toc/2305-6304 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 3, p 283
allfields_unstemmed	10.3390/toxics11030283 doi (DE-627)DOAJ087224054 (DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867 DE-627 ger DE-627 rakwb eng TP1-1185 Ntombikayise Mahaye verfasserin aut Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated. <i<Pseudokirchneriella subcapitata</i< cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll <i<a</i< content Chemical technology Ndeke Musee verfasserin aut In Toxics MDPI AG, 2014 11(2023), 3, p 283 (DE-627)768577497 (DE-600)2733883-6 23056304 nnns volume:11 year:2023 number:3, p 283 https://doi.org/10.3390/toxics11030283 kostenfrei https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867 kostenfrei https://www.mdpi.com/2305-6304/11/3/283 kostenfrei https://doaj.org/toc/2305-6304 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 3, p 283
allfieldsGer	10.3390/toxics11030283 doi (DE-627)DOAJ087224054 (DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867 DE-627 ger DE-627 rakwb eng TP1-1185 Ntombikayise Mahaye verfasserin aut Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated. <i<Pseudokirchneriella subcapitata</i< cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll <i<a</i< content Chemical technology Ndeke Musee verfasserin aut In Toxics MDPI AG, 2014 11(2023), 3, p 283 (DE-627)768577497 (DE-600)2733883-6 23056304 nnns volume:11 year:2023 number:3, p 283 https://doi.org/10.3390/toxics11030283 kostenfrei https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867 kostenfrei https://www.mdpi.com/2305-6304/11/3/283 kostenfrei https://doaj.org/toc/2305-6304 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 3, p 283
allfieldsSound	10.3390/toxics11030283 doi (DE-627)DOAJ087224054 (DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867 DE-627 ger DE-627 rakwb eng TP1-1185 Ntombikayise Mahaye verfasserin aut Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated. <i<Pseudokirchneriella subcapitata</i< cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll <i<a</i< content Chemical technology Ndeke Musee verfasserin aut In Toxics MDPI AG, 2014 11(2023), 3, p 283 (DE-627)768577497 (DE-600)2733883-6 23056304 nnns volume:11 year:2023 number:3, p 283 https://doi.org/10.3390/toxics11030283 kostenfrei https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867 kostenfrei https://www.mdpi.com/2305-6304/11/3/283 kostenfrei https://doaj.org/toc/2305-6304 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 3, p 283
language	English
source	In Toxics 11(2023), 3, p 283 volume:11 year:2023 number:3, p 283
sourceStr	In Toxics 11(2023), 3, p 283 volume:11 year:2023 number:3, p 283
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	<i<Pseudokirchneriella subcapitata</i< cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll <i<a</i< content Chemical technology
isfreeaccess_bool	true
container_title	Toxics
authorswithroles_txt_mv	Ntombikayise Mahaye @@aut@@ Ndeke Musee @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	768577497
id	DOAJ087224054
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ087224054</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413043754.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230331s2023 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/toxics11030283</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ087224054</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TP1-1185</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Ntombikayise Mahaye</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a"><i<Pseudokirchneriella subcapitata</i<</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">cerium oxide nanoparticles</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">DNA stability</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">RAPD-PCR</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">growth effect</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">chlorophyll <i<a</i< content</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Chemical technology</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ndeke Musee</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Toxics</subfield><subfield code="d">MDPI AG, 2014</subfield><subfield code="g">11(2023), 3, p 283</subfield><subfield code="w">(DE-627)768577497</subfield><subfield code="w">(DE-600)2733883-6</subfield><subfield code="x">23056304</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:11</subfield><subfield code="g">year:2023</subfield><subfield code="g">number:3, p 283</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/toxics11030283</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/2305-6304/11/3/283</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2305-6304</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">11</subfield><subfield code="j">2023</subfield><subfield code="e">3, p 283</subfield></datafield></record></collection>
callnumber-first	T - Technology
author	Ntombikayise Mahaye
spellingShingle	Ntombikayise Mahaye misc TP1-1185 misc <i<Pseudokirchneriella subcapitata</i< misc cerium oxide nanoparticles misc DNA stability misc RAPD-PCR misc growth effect misc chlorophyll <i<a</i< content misc Chemical technology Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles
authorStr	Ntombikayise Mahaye
ppnlink_with_tag_str_mv	@@773@@(DE-627)768577497
format	electronic Article
delete_txt_mv	keep
author_role	aut aut
collection	DOAJ
remote_str	true
callnumber-label	TP1-1185
illustrated	Not Illustrated
issn	23056304
topic_title	TP1-1185 Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles <i<Pseudokirchneriella subcapitata</i< cerium oxide nanoparticles DNA stability RAPD-PCR growth effect chlorophyll <i<a</i< content
topic	misc TP1-1185 misc <i<Pseudokirchneriella subcapitata</i< misc cerium oxide nanoparticles misc DNA stability misc RAPD-PCR misc growth effect misc chlorophyll <i<a</i< content misc Chemical technology
topic_unstemmed	misc TP1-1185 misc <i<Pseudokirchneriella subcapitata</i< misc cerium oxide nanoparticles misc DNA stability misc RAPD-PCR misc growth effect misc chlorophyll <i<a</i< content misc Chemical technology
topic_browse	misc TP1-1185 misc <i<Pseudokirchneriella subcapitata</i< misc cerium oxide nanoparticles misc DNA stability misc RAPD-PCR misc growth effect misc chlorophyll <i<a</i< content misc Chemical technology
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Toxics
hierarchy_parent_id	768577497
hierarchy_top_title	Toxics
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)768577497 (DE-600)2733883-6
title	Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles
ctrlnum	(DE-627)DOAJ087224054 (DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867
title_full	Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles
author_sort	Ntombikayise Mahaye
journal	Toxics
journalStr	Toxics
callnumber-first-code	T
lang_code	eng
isOA_bool	true
recordtype	marc
publishDateSort	2023
contenttype_str_mv	txt
author_browse	Ntombikayise Mahaye Ndeke Musee
container_volume	11
class	TP1-1185
format_se	Elektronische Aufsätze
author-letter	Ntombikayise Mahaye
doi_str_mv	10.3390/toxics11030283
author2-role	verfasserin
title_sort	evaluation of apical and molecular effects of algae <i<pseudokirchneriella subcapitata</i< to cerium oxide nanoparticles
callnumber	TP1-1185
title_auth	Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles
abstract	Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated.
abstractGer	Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated.
abstract_unstemmed	Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	3, p 283
title_short	Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles
url	https://doi.org/10.3390/toxics11030283 https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867 https://www.mdpi.com/2305-6304/11/3/283 https://doaj.org/toc/2305-6304
remote_bool	true
author2	Ndeke Musee
author2Str	Ndeke Musee
ppnlink	768577497
callnumber-subject	TP - Chemical Technology
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.3390/toxics11030283
callnumber-a	TP1-1185
up_date	2024-07-04T00:46:22.841Z
_version_	1803607325113581568
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ087224054</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413043754.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230331s2023 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/toxics11030283</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ087224054</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ50d56d35ca8f46c6afb00c0c39c93867</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TP1-1185</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Ntombikayise Mahaye</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Cerium oxide engineered nanoparticles (nCeO<sub<2</sub<) are widely used in various applications and are, also, increasingly being detected in different environmental matrixes. However, their impacts on the aquatic environment remain poorly quantified. Hence, there is a need to investigate their effects on non-target aquatic organisms. Here, we evaluated the cytotoxic and genotoxic effects of <25 nm uncoated-nCeO<sub<2</sub< on algae <i<Pseudokirchneriella subcapitata</i<. Apical (growth and chlorophyll <i<a</i< (Chl <i<a</i<) content) and genotoxic effects were investigated at 62.5–1000 µg/L after 72 and 168 h. Results demonstrated that nCeO<sub<2</sub< induced significant growth inhibition after 72 h and promotion post 96–168 h. Conversely, nCeO<sub<2</sub< induced enhanced Chl <i<a</i< content post 72 h, but no significant changes were observed between nCeO<sub<2</sub<–exposed and control samples after 168 h. Hence, the results indicate <i<P. subcapitata</i< photosynthetic system recovery ability to nCeO<sub<2</sub< effects under chronic-exposure conditions. RAPD-PCR profiles showed the appearance and/or disappearance of normal bands relative to controls; indicative of DNA damage and/or DNA mutation. Unlike cell recovery observed post 96 h, DNA damage persisted over 168 h. Thus, sub-lethal nCeO<sub<2</sub<-induced toxicological effects may pose a more serious threat to algae than at present anticipated.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a"><i<Pseudokirchneriella subcapitata</i<</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">cerium oxide nanoparticles</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">DNA stability</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">RAPD-PCR</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">growth effect</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">chlorophyll <i<a</i< content</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Chemical technology</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ndeke Musee</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Toxics</subfield><subfield code="d">MDPI AG, 2014</subfield><subfield code="g">11(2023), 3, p 283</subfield><subfield code="w">(DE-627)768577497</subfield><subfield code="w">(DE-600)2733883-6</subfield><subfield code="x">23056304</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:11</subfield><subfield code="g">year:2023</subfield><subfield code="g">number:3, p 283</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/toxics11030283</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/50d56d35ca8f46c6afb00c0c39c93867</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/2305-6304/11/3/283</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2305-6304</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">11</subfield><subfield code="j">2023</subfield><subfield code="e">3, p 283</subfield></datafield></record></collection>
score	7.398863

Nicht das Richtige dabei?

Schreiben Sie uns!

Evaluation of Apical and Molecular Effects of Algae <i<Pseudokirchneriella subcapitata</i< to Cerium Oxide Nanoparticles

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?