Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity

Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we d...
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Autor*in:	Mijin Kim [verfasserIn] Hanlin Zhang [verfasserIn] Taeho Kim [verfasserIn] Yutaro Mori [verfasserIn] Tomohiro Okura [verfasserIn] Kiyoji Tanaka [verfasserIn] Tomonori Isobe [verfasserIn] Takeji Sakae [verfasserIn] Sechang Oh [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	vibration therapy obesity impaired glucose tolerance myokine muscle stiffness

Übergeordnetes Werk:	In: International Journal of Environmental Research and Public Health - MDPI AG, 2005, 20(2023), 4708, p 4708
Übergeordnetes Werk:	volume:20 ; year:2023 ; number:4708, p 4708

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3390/ijerph20064708

Katalog-ID:	DOAJ087351730

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520			\|a Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future.
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allfields	10.3390/ijerph20064708 doi (DE-627)DOAJ087351730 (DE-599)DOAJ954a6159f95c4354b5672bbb8065194c DE-627 ger DE-627 rakwb eng Mijin Kim verfasserin aut Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future. vibration therapy obesity impaired glucose tolerance myokine muscle stiffness Medicine R Hanlin Zhang verfasserin aut Taeho Kim verfasserin aut Yutaro Mori verfasserin aut Tomohiro Okura verfasserin aut Kiyoji Tanaka verfasserin aut Tomonori Isobe verfasserin aut Takeji Sakae verfasserin aut Sechang Oh verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 20(2023), 4708, p 4708 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:20 year:2023 number:4708, p 4708 https://doi.org/10.3390/ijerph20064708 kostenfrei https://doaj.org/article/954a6159f95c4354b5672bbb8065194c kostenfrei https://www.mdpi.com/1660-4601/20/6/4708 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 4708, p 4708
spelling	10.3390/ijerph20064708 doi (DE-627)DOAJ087351730 (DE-599)DOAJ954a6159f95c4354b5672bbb8065194c DE-627 ger DE-627 rakwb eng Mijin Kim verfasserin aut Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future. vibration therapy obesity impaired glucose tolerance myokine muscle stiffness Medicine R Hanlin Zhang verfasserin aut Taeho Kim verfasserin aut Yutaro Mori verfasserin aut Tomohiro Okura verfasserin aut Kiyoji Tanaka verfasserin aut Tomonori Isobe verfasserin aut Takeji Sakae verfasserin aut Sechang Oh verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 20(2023), 4708, p 4708 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:20 year:2023 number:4708, p 4708 https://doi.org/10.3390/ijerph20064708 kostenfrei https://doaj.org/article/954a6159f95c4354b5672bbb8065194c kostenfrei https://www.mdpi.com/1660-4601/20/6/4708 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 4708, p 4708
allfields_unstemmed	10.3390/ijerph20064708 doi (DE-627)DOAJ087351730 (DE-599)DOAJ954a6159f95c4354b5672bbb8065194c DE-627 ger DE-627 rakwb eng Mijin Kim verfasserin aut Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future. vibration therapy obesity impaired glucose tolerance myokine muscle stiffness Medicine R Hanlin Zhang verfasserin aut Taeho Kim verfasserin aut Yutaro Mori verfasserin aut Tomohiro Okura verfasserin aut Kiyoji Tanaka verfasserin aut Tomonori Isobe verfasserin aut Takeji Sakae verfasserin aut Sechang Oh verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 20(2023), 4708, p 4708 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:20 year:2023 number:4708, p 4708 https://doi.org/10.3390/ijerph20064708 kostenfrei https://doaj.org/article/954a6159f95c4354b5672bbb8065194c kostenfrei https://www.mdpi.com/1660-4601/20/6/4708 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 4708, p 4708
allfieldsGer	10.3390/ijerph20064708 doi (DE-627)DOAJ087351730 (DE-599)DOAJ954a6159f95c4354b5672bbb8065194c DE-627 ger DE-627 rakwb eng Mijin Kim verfasserin aut Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future. vibration therapy obesity impaired glucose tolerance myokine muscle stiffness Medicine R Hanlin Zhang verfasserin aut Taeho Kim verfasserin aut Yutaro Mori verfasserin aut Tomohiro Okura verfasserin aut Kiyoji Tanaka verfasserin aut Tomonori Isobe verfasserin aut Takeji Sakae verfasserin aut Sechang Oh verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 20(2023), 4708, p 4708 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:20 year:2023 number:4708, p 4708 https://doi.org/10.3390/ijerph20064708 kostenfrei https://doaj.org/article/954a6159f95c4354b5672bbb8065194c kostenfrei https://www.mdpi.com/1660-4601/20/6/4708 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 4708, p 4708
allfieldsSound	10.3390/ijerph20064708 doi (DE-627)DOAJ087351730 (DE-599)DOAJ954a6159f95c4354b5672bbb8065194c DE-627 ger DE-627 rakwb eng Mijin Kim verfasserin aut Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future. vibration therapy obesity impaired glucose tolerance myokine muscle stiffness Medicine R Hanlin Zhang verfasserin aut Taeho Kim verfasserin aut Yutaro Mori verfasserin aut Tomohiro Okura verfasserin aut Kiyoji Tanaka verfasserin aut Tomonori Isobe verfasserin aut Takeji Sakae verfasserin aut Sechang Oh verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 20(2023), 4708, p 4708 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:20 year:2023 number:4708, p 4708 https://doi.org/10.3390/ijerph20064708 kostenfrei https://doaj.org/article/954a6159f95c4354b5672bbb8065194c kostenfrei https://www.mdpi.com/1660-4601/20/6/4708 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 4708, p 4708
language	English
source	In International Journal of Environmental Research and Public Health 20(2023), 4708, p 4708 volume:20 year:2023 number:4708, p 4708
sourceStr	In International Journal of Environmental Research and Public Health 20(2023), 4708, p 4708 volume:20 year:2023 number:4708, p 4708
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topic_facet	vibration therapy obesity impaired glucose tolerance myokine muscle stiffness Medicine R
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publishDateDaySort_date	2023-01-01T00:00:00Z
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author	Mijin Kim
spellingShingle	Mijin Kim misc vibration therapy misc obesity misc impaired glucose tolerance misc myokine misc muscle stiffness misc Medicine misc R Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity
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issn	16604601
topic_title	Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity vibration therapy obesity impaired glucose tolerance myokine muscle stiffness
topic	misc vibration therapy misc obesity misc impaired glucose tolerance misc myokine misc muscle stiffness misc Medicine misc R
topic_unstemmed	misc vibration therapy misc obesity misc impaired glucose tolerance misc myokine misc muscle stiffness misc Medicine misc R
topic_browse	misc vibration therapy misc obesity misc impaired glucose tolerance misc myokine misc muscle stiffness misc Medicine misc R
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
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title	Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity
ctrlnum	(DE-627)DOAJ087351730 (DE-599)DOAJ954a6159f95c4354b5672bbb8065194c
title_full	Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity
author_sort	Mijin Kim
journal	International Journal of Environmental Research and Public Health
journalStr	International Journal of Environmental Research and Public Health
lang_code	eng
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publishDateSort	2023
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author_browse	Mijin Kim Hanlin Zhang Taeho Kim Yutaro Mori Tomohiro Okura Kiyoji Tanaka Tomonori Isobe Takeji Sakae Sechang Oh
container_volume	20
format_se	Elektronische Aufsätze
author-letter	Mijin Kim
doi_str_mv	10.3390/ijerph20064708
author2-role	verfasserin
title_sort	novel approach for glycemic management incorporating vibration stimulation of skeletal muscle in obesity
title_auth	Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity
abstract	Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future.
abstractGer	Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future.
abstract_unstemmed	Because obesity is associated with impaired glucose tolerance and type 2 diabetes (T2D), it is important to manage the blood glucose level at an early stage. Nevertheless, people with obesity have significantly lower resistance to muscle fatigue after exercise and exercise adherence. Therefore, we developed a novel “Relaxing-Vibration Training (<sub<R</sub<VT)” consisting of 25 postures using vibration stimulation of skeletal muscle and determined the feasibility of <sub<R</sub<VT for glycemic management. Thirty-one participants with obesity were enrolled in a controlled trial (CT) and experimental trial (ET) based on a 75 g oral glucose tolerance test (OGTT). During the CT, participants were required to rest in a quiet room. During the ET, the <sub<R</sub<VT program (50 Hz, 4 mm), consisting of 25 postures of relaxation and stretching on the vibratory platform, was performed for 40 min. Subsequently, the participants rested as in the CT. Subjective fatigue and muscle stiffness measurements and blood collection were conducted before and after <sub<R</sub<VT. In both the CT and ET, interstitial fluid (ISF) glucose concentrations were measured every 15 min for 2 h. The incremental area under the curve value of real-time ISF glucose during an OGTT was significantly lower in the ET than in the CT (ET: 7476.5 ± 2974.9, CT: 8078.5 ± 3077.7, effect size r = 0.4). Additionally, the levels of metabolic glucose regulators associated with myokines, muscle stiffness, and subjective fatigue significantly improved after <sub<R</sub<VT. This novel <sub<R</sub<VT suggests that it is effective in glycemic management with great potential to improve impaired glucose tolerance and T2D with obesity in the future.
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container_issue	4708, p 4708
title_short	Novel Approach for Glycemic Management Incorporating Vibration Stimulation of Skeletal Muscle in Obesity
url	https://doi.org/10.3390/ijerph20064708 https://doaj.org/article/954a6159f95c4354b5672bbb8065194c https://www.mdpi.com/1660-4601/20/6/4708 https://doaj.org/toc/1661-7827 https://doaj.org/toc/1660-4601
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author2	Hanlin Zhang Taeho Kim Yutaro Mori Tomohiro Okura Kiyoji Tanaka Tomonori Isobe Takeji Sakae Sechang Oh
author2Str	Hanlin Zhang Taeho Kim Yutaro Mori Tomohiro Okura Kiyoji Tanaka Tomonori Isobe Takeji Sakae Sechang Oh
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doi_str	10.3390/ijerph20064708
up_date	2024-07-04T01:19:42.931Z
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