Longitudinal development of the cerebellum in human infants during the first 800 days

Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cereb...
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Autor*in:	Ya Wang [verfasserIn] Liangjun Chen [verfasserIn] Zhengwang Wu [verfasserIn] Tengfei Li [verfasserIn] Yue Sun [verfasserIn] Jiale Cheng [verfasserIn] Hongtu Zhu [verfasserIn] Weili Lin [verfasserIn] Li Wang [verfasserIn] Wenhua Huang [verfasserIn] Gang Li [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	CP: Neuroscience

Übergeordnetes Werk:	In: Cell Reports - Elsevier, 2015, 42(2023), 4, Seite 112281-
Übergeordnetes Werk:	volume:42 ; year:2023 ; number:4 ; pages:112281-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.celrep.2023.112281

Katalog-ID:	DOAJ087566273

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520			\|a Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined.
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spelling	10.1016/j.celrep.2023.112281 doi (DE-627)DOAJ087566273 (DE-599)DOAJe7ed4cbc01cf4429810b081402a9247c DE-627 ger DE-627 rakwb eng QH301-705.5 Ya Wang verfasserin aut Longitudinal development of the cerebellum in human infants during the first 800 days 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined. CP: Neuroscience Biology (General) Liangjun Chen verfasserin aut Zhengwang Wu verfasserin aut Tengfei Li verfasserin aut Yue Sun verfasserin aut Jiale Cheng verfasserin aut Hongtu Zhu verfasserin aut Weili Lin verfasserin aut Li Wang verfasserin aut Wenhua Huang verfasserin aut Gang Li verfasserin aut In Cell Reports Elsevier, 2015 42(2023), 4, Seite 112281- (DE-627)684964562 (DE-600)2649101-1 22111247 nnns volume:42 year:2023 number:4 pages:112281- https://doi.org/10.1016/j.celrep.2023.112281 kostenfrei https://doaj.org/article/e7ed4cbc01cf4429810b081402a9247c kostenfrei http://www.sciencedirect.com/science/article/pii/S2211124723002929 kostenfrei https://doaj.org/toc/2211-1247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 42 2023 4 112281-
allfields_unstemmed	10.1016/j.celrep.2023.112281 doi (DE-627)DOAJ087566273 (DE-599)DOAJe7ed4cbc01cf4429810b081402a9247c DE-627 ger DE-627 rakwb eng QH301-705.5 Ya Wang verfasserin aut Longitudinal development of the cerebellum in human infants during the first 800 days 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined. CP: Neuroscience Biology (General) Liangjun Chen verfasserin aut Zhengwang Wu verfasserin aut Tengfei Li verfasserin aut Yue Sun verfasserin aut Jiale Cheng verfasserin aut Hongtu Zhu verfasserin aut Weili Lin verfasserin aut Li Wang verfasserin aut Wenhua Huang verfasserin aut Gang Li verfasserin aut In Cell Reports Elsevier, 2015 42(2023), 4, Seite 112281- (DE-627)684964562 (DE-600)2649101-1 22111247 nnns volume:42 year:2023 number:4 pages:112281- https://doi.org/10.1016/j.celrep.2023.112281 kostenfrei https://doaj.org/article/e7ed4cbc01cf4429810b081402a9247c kostenfrei http://www.sciencedirect.com/science/article/pii/S2211124723002929 kostenfrei https://doaj.org/toc/2211-1247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 42 2023 4 112281-
allfieldsGer	10.1016/j.celrep.2023.112281 doi (DE-627)DOAJ087566273 (DE-599)DOAJe7ed4cbc01cf4429810b081402a9247c DE-627 ger DE-627 rakwb eng QH301-705.5 Ya Wang verfasserin aut Longitudinal development of the cerebellum in human infants during the first 800 days 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined. CP: Neuroscience Biology (General) Liangjun Chen verfasserin aut Zhengwang Wu verfasserin aut Tengfei Li verfasserin aut Yue Sun verfasserin aut Jiale Cheng verfasserin aut Hongtu Zhu verfasserin aut Weili Lin verfasserin aut Li Wang verfasserin aut Wenhua Huang verfasserin aut Gang Li verfasserin aut In Cell Reports Elsevier, 2015 42(2023), 4, Seite 112281- (DE-627)684964562 (DE-600)2649101-1 22111247 nnns volume:42 year:2023 number:4 pages:112281- https://doi.org/10.1016/j.celrep.2023.112281 kostenfrei https://doaj.org/article/e7ed4cbc01cf4429810b081402a9247c kostenfrei http://www.sciencedirect.com/science/article/pii/S2211124723002929 kostenfrei https://doaj.org/toc/2211-1247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 42 2023 4 112281-
allfieldsSound	10.1016/j.celrep.2023.112281 doi (DE-627)DOAJ087566273 (DE-599)DOAJe7ed4cbc01cf4429810b081402a9247c DE-627 ger DE-627 rakwb eng QH301-705.5 Ya Wang verfasserin aut Longitudinal development of the cerebellum in human infants during the first 800 days 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined. CP: Neuroscience Biology (General) Liangjun Chen verfasserin aut Zhengwang Wu verfasserin aut Tengfei Li verfasserin aut Yue Sun verfasserin aut Jiale Cheng verfasserin aut Hongtu Zhu verfasserin aut Weili Lin verfasserin aut Li Wang verfasserin aut Wenhua Huang verfasserin aut Gang Li verfasserin aut In Cell Reports Elsevier, 2015 42(2023), 4, Seite 112281- (DE-627)684964562 (DE-600)2649101-1 22111247 nnns volume:42 year:2023 number:4 pages:112281- https://doi.org/10.1016/j.celrep.2023.112281 kostenfrei https://doaj.org/article/e7ed4cbc01cf4429810b081402a9247c kostenfrei http://www.sciencedirect.com/science/article/pii/S2211124723002929 kostenfrei https://doaj.org/toc/2211-1247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 42 2023 4 112281-
language	English
source	In Cell Reports 42(2023), 4, Seite 112281- volume:42 year:2023 number:4 pages:112281-
sourceStr	In Cell Reports 42(2023), 4, Seite 112281- volume:42 year:2023 number:4 pages:112281-
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	CP: Neuroscience Biology (General)
isfreeaccess_bool	true
container_title	Cell Reports
authorswithroles_txt_mv	Ya Wang @@aut@@ Liangjun Chen @@aut@@ Zhengwang Wu @@aut@@ Tengfei Li @@aut@@ Yue Sun @@aut@@ Jiale Cheng @@aut@@ Hongtu Zhu @@aut@@ Weili Lin @@aut@@ Li Wang @@aut@@ Wenhua Huang @@aut@@ Gang Li @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	684964562
id	DOAJ087566273
language_de	englisch
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callnumber-first	Q - Science
author	Ya Wang
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topic_title	QH301-705.5 Longitudinal development of the cerebellum in human infants during the first 800 days CP: Neuroscience
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title	Longitudinal development of the cerebellum in human infants during the first 800 days
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title_full	Longitudinal development of the cerebellum in human infants during the first 800 days
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author_browse	Ya Wang Liangjun Chen Zhengwang Wu Tengfei Li Yue Sun Jiale Cheng Hongtu Zhu Weili Lin Li Wang Wenhua Huang Gang Li
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title_sort	longitudinal development of the cerebellum in human infants during the first 800 days
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title_auth	Longitudinal development of the cerebellum in human infants during the first 800 days
abstract	Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined.
abstractGer	Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined.
abstract_unstemmed	Summary: Revealing early dynamic development of the normative cerebellar structures contributes to exploring cerebellum-related neurodevelopmental disorders. Here, leveraging infant-tailored cerebellar image processing techniques, we studied the dynamic volumetric developmental trajectories of cerebellum and 27 cerebellar sub-regions and their relationships with behavioral scores based on 511 high-resolution structural MRI scans during the first 800 postnatal days. The ratio of the entire cerebellum to the intracranial volume increases rapidly at first and then peaks at 13 months after birth. Both the absolute and relative volumes of most cerebellar sub-structures exhibit rapid increase at first, then the relative volumes decrease slightly after arriving at peaks (except for X lobules). Each lobule depicts larger absolute volume in males than in females. The within-subject variation of the cerebellar volumetric percentile score is generally stable. The volumetric development of several lobules (e.g., V, Crus I, and Crus II) has a significantly positive correlation with fine motor skills during the age range examined.
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title_short	Longitudinal development of the cerebellum in human infants during the first 800 days
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Longitudinal development of the cerebellum in human infants during the first 800 days

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