Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management

Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study o...
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Autor*in:	Hosam Hamed [verfasserIn] Mohamed Abdel Wahab [verfasserIn] Youssif Elmahdy [verfasserIn] Rihame M. Abd El-Wahab [verfasserIn] El-Sayed Abou El-Magd [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Small intestine Gastrointestinal stromal tumors Anemia of unknown origin

Übergeordnetes Werk:	In: World Journal of Surgical Oncology - BMC, 2003, 21(2023), 1, Seite 8
Übergeordnetes Werk:	volume:21 ; year:2023 ; number:1 ; pages:8

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/s12957-023-02968-0

Katalog-ID:	DOAJ087737752

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520			\|a Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates.
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allfields	10.1186/s12957-023-02968-0 doi (DE-627)DOAJ087737752 (DE-599)DOAJ30e77b5a867146ad95fb9792a6a698c7 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Hosam Hamed verfasserin aut Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates. Small intestine Gastrointestinal stromal tumors Anemia of unknown origin Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Mohamed Abdel Wahab verfasserin aut Youssif Elmahdy verfasserin aut Rihame M. Abd El-Wahab verfasserin aut El-Sayed Abou El-Magd verfasserin aut In World Journal of Surgical Oncology BMC, 2003 21(2023), 1, Seite 8 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:21 year:2023 number:1 pages:8 https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/article/30e77b5a867146ad95fb9792a6a698c7 kostenfrei https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 8
spelling	10.1186/s12957-023-02968-0 doi (DE-627)DOAJ087737752 (DE-599)DOAJ30e77b5a867146ad95fb9792a6a698c7 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Hosam Hamed verfasserin aut Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates. Small intestine Gastrointestinal stromal tumors Anemia of unknown origin Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Mohamed Abdel Wahab verfasserin aut Youssif Elmahdy verfasserin aut Rihame M. Abd El-Wahab verfasserin aut El-Sayed Abou El-Magd verfasserin aut In World Journal of Surgical Oncology BMC, 2003 21(2023), 1, Seite 8 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:21 year:2023 number:1 pages:8 https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/article/30e77b5a867146ad95fb9792a6a698c7 kostenfrei https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 8
allfields_unstemmed	10.1186/s12957-023-02968-0 doi (DE-627)DOAJ087737752 (DE-599)DOAJ30e77b5a867146ad95fb9792a6a698c7 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Hosam Hamed verfasserin aut Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates. Small intestine Gastrointestinal stromal tumors Anemia of unknown origin Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Mohamed Abdel Wahab verfasserin aut Youssif Elmahdy verfasserin aut Rihame M. Abd El-Wahab verfasserin aut El-Sayed Abou El-Magd verfasserin aut In World Journal of Surgical Oncology BMC, 2003 21(2023), 1, Seite 8 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:21 year:2023 number:1 pages:8 https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/article/30e77b5a867146ad95fb9792a6a698c7 kostenfrei https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 8
allfieldsGer	10.1186/s12957-023-02968-0 doi (DE-627)DOAJ087737752 (DE-599)DOAJ30e77b5a867146ad95fb9792a6a698c7 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Hosam Hamed verfasserin aut Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates. Small intestine Gastrointestinal stromal tumors Anemia of unknown origin Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Mohamed Abdel Wahab verfasserin aut Youssif Elmahdy verfasserin aut Rihame M. Abd El-Wahab verfasserin aut El-Sayed Abou El-Magd verfasserin aut In World Journal of Surgical Oncology BMC, 2003 21(2023), 1, Seite 8 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:21 year:2023 number:1 pages:8 https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/article/30e77b5a867146ad95fb9792a6a698c7 kostenfrei https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 8
allfieldsSound	10.1186/s12957-023-02968-0 doi (DE-627)DOAJ087737752 (DE-599)DOAJ30e77b5a867146ad95fb9792a6a698c7 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Hosam Hamed verfasserin aut Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates. Small intestine Gastrointestinal stromal tumors Anemia of unknown origin Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Mohamed Abdel Wahab verfasserin aut Youssif Elmahdy verfasserin aut Rihame M. Abd El-Wahab verfasserin aut El-Sayed Abou El-Magd verfasserin aut In World Journal of Surgical Oncology BMC, 2003 21(2023), 1, Seite 8 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:21 year:2023 number:1 pages:8 https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/article/30e77b5a867146ad95fb9792a6a698c7 kostenfrei https://doi.org/10.1186/s12957-023-02968-0 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2023 1 8
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Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Small intestine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Gastrointestinal stromal tumors</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anemia of unknown origin</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Surgery</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neoplasms. Tumors. Oncology. 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callnumber-first	R - Medicine
author	Hosam Hamed
spellingShingle	Hosam Hamed misc RD1-811 misc RC254-282 misc Small intestine misc Gastrointestinal stromal tumors misc Anemia of unknown origin misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management
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topic_title	RD1-811 RC254-282 Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management Small intestine Gastrointestinal stromal tumors Anemia of unknown origin
topic	misc RD1-811 misc RC254-282 misc Small intestine misc Gastrointestinal stromal tumors misc Anemia of unknown origin misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RD1-811 misc RC254-282 misc Small intestine misc Gastrointestinal stromal tumors misc Anemia of unknown origin misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title_full	Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management
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author_browse	Hosam Hamed Mohamed Abdel Wahab Youssif Elmahdy Rihame M. Abd El-Wahab El-Sayed Abou El-Magd
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title_sort	gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management
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title_auth	Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management
abstract	Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates.
abstractGer	Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates.
abstract_unstemmed	Abstract Purposes Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates.
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title_short	Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management
url	https://doi.org/10.1186/s12957-023-02968-0 https://doaj.org/article/30e77b5a867146ad95fb9792a6a698c7 https://doaj.org/toc/1477-7819
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author2	Mohamed Abdel Wahab Youssif Elmahdy Rihame M. Abd El-Wahab El-Sayed Abou El-Magd
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up_date	2024-07-03T13:38:29.274Z
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Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management. Methods A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST). Results Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered. Conclusion Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Small intestine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Gastrointestinal stromal tumors</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anemia of unknown origin</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Surgery</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neoplasms. Tumors. Oncology. 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Gastrointestinal stromal tumors of the small intestine: the challenge of diagnosis and the outcome of management

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