Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices

Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentine...
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Autor*in:	Roxana Schwab [verfasserIn] Kathrin Stewen [verfasserIn] Theresa-Louise Bührer [verfasserIn] Mona W. Schmidt [verfasserIn] Josche van der Ven [verfasserIn] Katharina Anic [verfasserIn] Valerie C. Linz [verfasserIn] Bashar Haj Hamoud [verfasserIn] Walburgis Brenner [verfasserIn] Katharina Peters [verfasserIn] Anne-Sophie Heimes [verfasserIn] Katrin Almstedt [verfasserIn] Slavomir Krajnak [verfasserIn] Wolfgang Weikel [verfasserIn] Marco J. Battista [verfasserIn] Christian Dannecker [verfasserIn] Annette Hasenburg [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center

Übergeordnetes Werk:	In: Journal of Clinical Medicine - MDPI AG, 2013, 12(2023), 5, p 2048
Übergeordnetes Werk:	volume:12 ; year:2023 ; number:5, p 2048

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/jcm12052048

Katalog-ID:	DOAJ087996227

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520			\|a Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient.
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allfields	10.3390/jcm12052048 doi (DE-627)DOAJ087996227 (DE-599)DOAJ40df9919ee8248408f7b4f2e0d5c5c81 DE-627 ger DE-627 rakwb eng Roxana Schwab verfasserin aut Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient. vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center Medicine R Kathrin Stewen verfasserin aut Theresa-Louise Bührer verfasserin aut Mona W. Schmidt verfasserin aut Josche van der Ven verfasserin aut Katharina Anic verfasserin aut Valerie C. Linz verfasserin aut Bashar Haj Hamoud verfasserin aut Walburgis Brenner verfasserin aut Katharina Peters verfasserin aut Anne-Sophie Heimes verfasserin aut Katrin Almstedt verfasserin aut Slavomir Krajnak verfasserin aut Wolfgang Weikel verfasserin aut Marco J. Battista verfasserin aut Christian Dannecker verfasserin aut Annette Hasenburg verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 5, p 2048 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:5, p 2048 https://doi.org/10.3390/jcm12052048 kostenfrei https://doaj.org/article/40df9919ee8248408f7b4f2e0d5c5c81 kostenfrei https://www.mdpi.com/2077-0383/12/5/2048 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 5, p 2048
spelling	10.3390/jcm12052048 doi (DE-627)DOAJ087996227 (DE-599)DOAJ40df9919ee8248408f7b4f2e0d5c5c81 DE-627 ger DE-627 rakwb eng Roxana Schwab verfasserin aut Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient. vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center Medicine R Kathrin Stewen verfasserin aut Theresa-Louise Bührer verfasserin aut Mona W. Schmidt verfasserin aut Josche van der Ven verfasserin aut Katharina Anic verfasserin aut Valerie C. Linz verfasserin aut Bashar Haj Hamoud verfasserin aut Walburgis Brenner verfasserin aut Katharina Peters verfasserin aut Anne-Sophie Heimes verfasserin aut Katrin Almstedt verfasserin aut Slavomir Krajnak verfasserin aut Wolfgang Weikel verfasserin aut Marco J. Battista verfasserin aut Christian Dannecker verfasserin aut Annette Hasenburg verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 5, p 2048 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:5, p 2048 https://doi.org/10.3390/jcm12052048 kostenfrei https://doaj.org/article/40df9919ee8248408f7b4f2e0d5c5c81 kostenfrei https://www.mdpi.com/2077-0383/12/5/2048 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 5, p 2048
allfields_unstemmed	10.3390/jcm12052048 doi (DE-627)DOAJ087996227 (DE-599)DOAJ40df9919ee8248408f7b4f2e0d5c5c81 DE-627 ger DE-627 rakwb eng Roxana Schwab verfasserin aut Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient. vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center Medicine R Kathrin Stewen verfasserin aut Theresa-Louise Bührer verfasserin aut Mona W. Schmidt verfasserin aut Josche van der Ven verfasserin aut Katharina Anic verfasserin aut Valerie C. Linz verfasserin aut Bashar Haj Hamoud verfasserin aut Walburgis Brenner verfasserin aut Katharina Peters verfasserin aut Anne-Sophie Heimes verfasserin aut Katrin Almstedt verfasserin aut Slavomir Krajnak verfasserin aut Wolfgang Weikel verfasserin aut Marco J. Battista verfasserin aut Christian Dannecker verfasserin aut Annette Hasenburg verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 5, p 2048 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:5, p 2048 https://doi.org/10.3390/jcm12052048 kostenfrei https://doaj.org/article/40df9919ee8248408f7b4f2e0d5c5c81 kostenfrei https://www.mdpi.com/2077-0383/12/5/2048 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 5, p 2048
allfieldsGer	10.3390/jcm12052048 doi (DE-627)DOAJ087996227 (DE-599)DOAJ40df9919ee8248408f7b4f2e0d5c5c81 DE-627 ger DE-627 rakwb eng Roxana Schwab verfasserin aut Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient. vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center Medicine R Kathrin Stewen verfasserin aut Theresa-Louise Bührer verfasserin aut Mona W. Schmidt verfasserin aut Josche van der Ven verfasserin aut Katharina Anic verfasserin aut Valerie C. Linz verfasserin aut Bashar Haj Hamoud verfasserin aut Walburgis Brenner verfasserin aut Katharina Peters verfasserin aut Anne-Sophie Heimes verfasserin aut Katrin Almstedt verfasserin aut Slavomir Krajnak verfasserin aut Wolfgang Weikel verfasserin aut Marco J. Battista verfasserin aut Christian Dannecker verfasserin aut Annette Hasenburg verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 5, p 2048 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:5, p 2048 https://doi.org/10.3390/jcm12052048 kostenfrei https://doaj.org/article/40df9919ee8248408f7b4f2e0d5c5c81 kostenfrei https://www.mdpi.com/2077-0383/12/5/2048 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 5, p 2048
allfieldsSound	10.3390/jcm12052048 doi (DE-627)DOAJ087996227 (DE-599)DOAJ40df9919ee8248408f7b4f2e0d5c5c81 DE-627 ger DE-627 rakwb eng Roxana Schwab verfasserin aut Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient. vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center Medicine R Kathrin Stewen verfasserin aut Theresa-Louise Bührer verfasserin aut Mona W. Schmidt verfasserin aut Josche van der Ven verfasserin aut Katharina Anic verfasserin aut Valerie C. Linz verfasserin aut Bashar Haj Hamoud verfasserin aut Walburgis Brenner verfasserin aut Katharina Peters verfasserin aut Anne-Sophie Heimes verfasserin aut Katrin Almstedt verfasserin aut Slavomir Krajnak verfasserin aut Wolfgang Weikel verfasserin aut Marco J. Battista verfasserin aut Christian Dannecker verfasserin aut Annette Hasenburg verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 5, p 2048 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:5, p 2048 https://doi.org/10.3390/jcm12052048 kostenfrei https://doaj.org/article/40df9919ee8248408f7b4f2e0d5c5c81 kostenfrei https://www.mdpi.com/2077-0383/12/5/2048 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 5, p 2048
language	English
source	In Journal of Clinical Medicine 12(2023), 5, p 2048 volume:12 year:2023 number:5, p 2048
sourceStr	In Journal of Clinical Medicine 12(2023), 5, p 2048 volume:12 year:2023 number:5, p 2048
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center Medicine R
isfreeaccess_bool	true
container_title	Journal of Clinical Medicine
authorswithroles_txt_mv	Roxana Schwab @@aut@@ Kathrin Stewen @@aut@@ Theresa-Louise Bührer @@aut@@ Mona W. Schmidt @@aut@@ Josche van der Ven @@aut@@ Katharina Anic @@aut@@ Valerie C. Linz @@aut@@ Bashar Haj Hamoud @@aut@@ Walburgis Brenner @@aut@@ Katharina Peters @@aut@@ Anne-Sophie Heimes @@aut@@ Katrin Almstedt @@aut@@ Slavomir Krajnak @@aut@@ Wolfgang Weikel @@aut@@ Marco J. Battista @@aut@@ Christian Dannecker @@aut@@ Annette Hasenburg @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	718632478
id	DOAJ087996227
language_de	englisch
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author	Roxana Schwab
spellingShingle	Roxana Schwab misc vulvar cancer misc rare disease misc sentinel node biopsy misc guidelines misc certified oncological center misc Medicine misc R Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices
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topic_title	Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices vulvar cancer rare disease sentinel node biopsy guidelines certified oncological center
topic	misc vulvar cancer misc rare disease misc sentinel node biopsy misc guidelines misc certified oncological center misc Medicine misc R
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title	Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices
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title_full	Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices
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author_browse	Roxana Schwab Kathrin Stewen Theresa-Louise Bührer Mona W. Schmidt Josche van der Ven Katharina Anic Valerie C. Linz Bashar Haj Hamoud Walburgis Brenner Katharina Peters Anne-Sophie Heimes Katrin Almstedt Slavomir Krajnak Wolfgang Weikel Marco J. Battista Christian Dannecker Annette Hasenburg
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title_sort	current approaches to the management of sentinel node procedures in early vulvar cancer in germany: a web-based nationwide analysis of practices
title_auth	Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices
abstract	Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient.
abstractGer	Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient.
abstract_unstemmed	Background: Lymph node involvement is the most important prognostic factor for recurrence and survival in vulvar cancer. Sentinel node (SN) procedure can be offered in well-selected patients with early vulvar cancer. This study aimed to assess current management practices with respect to the sentinel node procedure in women with early vulvar cancer in Germany. Methods: A Web-based survey was conducted. Questionnaires were e-mailed to 612 gynecology departments. Data were summarized as frequencies and analyzed using the chi-square test. Results: A total of 222 hospitals (36.27%) responded to the invitation to participate. Among the responders, 9.5% did not offer the SN procedure. However, 79.5% evaluated SNs by ultrastaging. In vulvar cancer of the midline with unilateral localized positive SN, 49.1% and 48.6% of respondents, respectively, would perform ipsilateral or bilateral inguinal lymph node dissection. Repeat SN procedure was performed by 16.2% of respondents. For isolated tumor cells (ITCs) or micrometastases, 28.1% and 60.5% of respondents, respectively, would perform inguinal lymph node dissection, whereas 19.3% and 23.8%, respectively, would opt for radiation without further surgical intervention. Notably, 50.9% of respondents would not initiate any further therapy and 15.1% would opt for expectant management. Conclusions: The majority of German hospitals implement the SN procedure. However, only 79.5% of respondents performed ultrastaging and only 28.1% were aware that ITC may affect survival in vulvar cancer. There is a need to ensure that the management of vulvar cancer follows the latest recommendations and clinical evidence. Deviations from state-of-the-art management should only be after a detailed discussion with the concerned patient.
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title_short	Current Approaches to the Management of Sentinel Node Procedures in Early Vulvar Cancer in Germany: A Web-Based Nationwide Analysis of Practices
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