Is cystatin C a good predictor of acute kidney injury after elective aortic surgery?
Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative pre...
Ausführliche Beschreibung
Autor*in: |
Maričić-Prijić Sanja [verfasserIn] Uvelin Arsen [verfasserIn] Anđelić Nada [verfasserIn] Plećaš-Đurić Aleksandra [verfasserIn] Popović Radmila [verfasserIn] Vicković Sanja [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch ; srp |
Erschienen: |
2022 |
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Übergeordnetes Werk: |
In: Vojnosanitetski Pregled - Military Health Department, Ministry of Defance, Serbia, 2012, 79(2022), 12, Seite 1193-1200 |
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Übergeordnetes Werk: |
volume:79 ; year:2022 ; number:12 ; pages:1193-1200 |
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Link aufrufen |
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DOI / URN: |
10.2298/VSP211031016M |
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Katalog-ID: |
DOAJ088050661 |
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520 | |a Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. | ||
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10.2298/VSP211031016M doi (DE-627)DOAJ088050661 (DE-599)DOAJe455b37896424cfb946fc7e757498154 DE-627 ger DE-627 rakwb eng srp R5-920 Maričić-Prijić Sanja verfasserin aut Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. aorta cystatin c elective surgical procedures kidney failure, acute prognosis sensitivity and specificity Medicine (General) Uvelin Arsen verfasserin aut Anđelić Nada verfasserin aut Plećaš-Đurić Aleksandra verfasserin aut Popović Radmila verfasserin aut Vicković Sanja verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 79(2022), 12, Seite 1193-1200 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:79 year:2022 number:12 pages:1193-1200 https://doi.org/10.2298/VSP211031016M kostenfrei https://doaj.org/article/e455b37896424cfb946fc7e757498154 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502200016M.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 79 2022 12 1193-1200 |
spelling |
10.2298/VSP211031016M doi (DE-627)DOAJ088050661 (DE-599)DOAJe455b37896424cfb946fc7e757498154 DE-627 ger DE-627 rakwb eng srp R5-920 Maričić-Prijić Sanja verfasserin aut Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. aorta cystatin c elective surgical procedures kidney failure, acute prognosis sensitivity and specificity Medicine (General) Uvelin Arsen verfasserin aut Anđelić Nada verfasserin aut Plećaš-Đurić Aleksandra verfasserin aut Popović Radmila verfasserin aut Vicković Sanja verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 79(2022), 12, Seite 1193-1200 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:79 year:2022 number:12 pages:1193-1200 https://doi.org/10.2298/VSP211031016M kostenfrei https://doaj.org/article/e455b37896424cfb946fc7e757498154 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502200016M.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 79 2022 12 1193-1200 |
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10.2298/VSP211031016M doi (DE-627)DOAJ088050661 (DE-599)DOAJe455b37896424cfb946fc7e757498154 DE-627 ger DE-627 rakwb eng srp R5-920 Maričić-Prijić Sanja verfasserin aut Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. aorta cystatin c elective surgical procedures kidney failure, acute prognosis sensitivity and specificity Medicine (General) Uvelin Arsen verfasserin aut Anđelić Nada verfasserin aut Plećaš-Đurić Aleksandra verfasserin aut Popović Radmila verfasserin aut Vicković Sanja verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 79(2022), 12, Seite 1193-1200 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:79 year:2022 number:12 pages:1193-1200 https://doi.org/10.2298/VSP211031016M kostenfrei https://doaj.org/article/e455b37896424cfb946fc7e757498154 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502200016M.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 79 2022 12 1193-1200 |
allfieldsGer |
10.2298/VSP211031016M doi (DE-627)DOAJ088050661 (DE-599)DOAJe455b37896424cfb946fc7e757498154 DE-627 ger DE-627 rakwb eng srp R5-920 Maričić-Prijić Sanja verfasserin aut Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. aorta cystatin c elective surgical procedures kidney failure, acute prognosis sensitivity and specificity Medicine (General) Uvelin Arsen verfasserin aut Anđelić Nada verfasserin aut Plećaš-Đurić Aleksandra verfasserin aut Popović Radmila verfasserin aut Vicković Sanja verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 79(2022), 12, Seite 1193-1200 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:79 year:2022 number:12 pages:1193-1200 https://doi.org/10.2298/VSP211031016M kostenfrei https://doaj.org/article/e455b37896424cfb946fc7e757498154 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502200016M.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 79 2022 12 1193-1200 |
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10.2298/VSP211031016M doi (DE-627)DOAJ088050661 (DE-599)DOAJe455b37896424cfb946fc7e757498154 DE-627 ger DE-627 rakwb eng srp R5-920 Maričić-Prijić Sanja verfasserin aut Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. aorta cystatin c elective surgical procedures kidney failure, acute prognosis sensitivity and specificity Medicine (General) Uvelin Arsen verfasserin aut Anđelić Nada verfasserin aut Plećaš-Đurić Aleksandra verfasserin aut Popović Radmila verfasserin aut Vicković Sanja verfasserin aut In Vojnosanitetski Pregled Military Health Department, Ministry of Defance, Serbia, 2012 79(2022), 12, Seite 1193-1200 (DE-627)474382613 (DE-600)2169819-3 24060720 nnns volume:79 year:2022 number:12 pages:1193-1200 https://doi.org/10.2298/VSP211031016M kostenfrei https://doaj.org/article/e455b37896424cfb946fc7e757498154 kostenfrei http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502200016M.pdf kostenfrei https://doaj.org/toc/0042-8450 Journal toc kostenfrei https://doaj.org/toc/2406-0720 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 79 2022 12 1193-1200 |
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Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? |
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Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? |
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Maričić-Prijić Sanja |
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Maričić-Prijić Sanja Uvelin Arsen Anđelić Nada Plećaš-Đurić Aleksandra Popović Radmila Vicković Sanja |
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is cystatin c a good predictor of acute kidney injury after elective aortic surgery? |
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Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? |
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Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. |
abstractGer |
Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. |
abstract_unstemmed |
Background/Aim. Acute kidney injury (AKI) is a frequent and serious complication after aortic surgery, which increases the length of hospital stay, costs, morbidity, and mortality. The aim of the study was to investigate the incidence of AKI and the most important preoperative and intraoperative predictive factors for AKI 72 hrs after elective infrarenal aortic surgery (IAS). Methods. This prospective observational study was performed at the Clinic of Anesthesia, Intensive Care and Pain Therapy, University Clinical Center of Vojvodina (UCCV), from October 2017 to April 2019. It included 140 adult patients who underwent an elective IAS. The occurrence of AKI was noted according to the Acute Kidney Injury Network (AKIN) criteria. A multivariate logistic regression model was used for potential predictive factors. Results. The incidence of AKI after the elective IAS at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, was 28.56%. According to the receiver operating characteristic (ROC) curve analysis, the cut-off value of cystatin C serum concentration of 1.14 mg/L had the highest sensitivity (82.5%) and specificity (76%) in the differentiation of patients who will develop AKI. The final model contained the following variables: the presence of chronic kidney disease, the preoperative serum concentration of cystatin C < 1.14 mg/L, the application of colloid solutions in volume < 500 mL during the operation, and the total intra-vascular fluid replacement volume < 59 mL/kg in the intraoperative period. Conclusion. The incidence of AKI at the Clinic of Anesthesia, Intensive Care and Pain Therapy, UCCV, is somewhat higher compared to the literature data. A presurgical value of cystatin C above 1.14 mg/L is a good predictor of AKI after the elective IAS. |
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Is cystatin C a good predictor of acute kidney injury after elective aortic surgery? |
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https://doi.org/10.2298/VSP211031016M https://doaj.org/article/e455b37896424cfb946fc7e757498154 http://www.doiserbia.nb.rs/img/doi/0042-8450/2022/0042-84502200016M.pdf https://doaj.org/toc/0042-8450 https://doaj.org/toc/2406-0720 |
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