Berberine: a comprehensive Approach to combat human maladies

ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, w...
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Autor*in:	Zarina Mushtaq [verfasserIn] Muhammad Imran [verfasserIn] Farhan Saeed [verfasserIn] Ali Imran [verfasserIn] Shinawar Waseem Ali [verfasserIn] Muhammad Shahbaz [verfasserIn] Suliman A. Alsagaby [verfasserIn] Yolanda Guerrero Sánchez [verfasserIn] Maryam Umar [verfasserIn] Muzzamal Hussain [verfasserIn] Waleed Al abdulmonme [verfasserIn] Entessar Al Jbawi [verfasserIn] Mahwish [verfasserIn] Ahmed H. El-Ghorab [verfasserIn] Mohamed A. Abdelgawad [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes

Übergeordnetes Werk:	In: International Journal of Food Properties - Taylor & Francis Group, 2018, 26(2023), 1, Seite 787-807
Übergeordnetes Werk:	volume:26 ; year:2023 ; number:1 ; pages:787-807

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.1080/10942912.2023.2184300

Katalog-ID:	DOAJ088389626

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520			\|a ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance.
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allfields	10.1080/10942912.2023.2184300 doi (DE-627)DOAJ088389626 (DE-599)DOAJd420daead2f94460b7b2f3de932f4f96 DE-627 ger DE-627 rakwb eng TX341-641 TP368-456 Zarina Mushtaq verfasserin aut Berberine: a comprehensive Approach to combat human maladies 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance. Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes Nutrition. Foods and food supply Food processing and manufacture Muhammad Imran verfasserin aut Farhan Saeed verfasserin aut Ali Imran verfasserin aut Shinawar Waseem Ali verfasserin aut Muhammad Shahbaz verfasserin aut Suliman A. Alsagaby verfasserin aut Yolanda Guerrero Sánchez verfasserin aut Maryam Umar verfasserin aut Muzzamal Hussain verfasserin aut Waleed Al abdulmonme verfasserin aut Entessar Al Jbawi verfasserin aut Mahwish verfasserin aut Ahmed H. El-Ghorab verfasserin aut Mohamed A. Abdelgawad verfasserin aut In International Journal of Food Properties Taylor & Francis Group, 2018 26(2023), 1, Seite 787-807 (DE-627)334376416 (DE-600)2057781-3 15322386 nnns volume:26 year:2023 number:1 pages:787-807 https://doi.org/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/article/d420daead2f94460b7b2f3de932f4f96 kostenfrei https://www.tandfonline.com/doi/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/toc/1094-2912 Journal toc kostenfrei https://doaj.org/toc/1532-2386 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2023 1 787-807
spelling	10.1080/10942912.2023.2184300 doi (DE-627)DOAJ088389626 (DE-599)DOAJd420daead2f94460b7b2f3de932f4f96 DE-627 ger DE-627 rakwb eng TX341-641 TP368-456 Zarina Mushtaq verfasserin aut Berberine: a comprehensive Approach to combat human maladies 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance. Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes Nutrition. Foods and food supply Food processing and manufacture Muhammad Imran verfasserin aut Farhan Saeed verfasserin aut Ali Imran verfasserin aut Shinawar Waseem Ali verfasserin aut Muhammad Shahbaz verfasserin aut Suliman A. Alsagaby verfasserin aut Yolanda Guerrero Sánchez verfasserin aut Maryam Umar verfasserin aut Muzzamal Hussain verfasserin aut Waleed Al abdulmonme verfasserin aut Entessar Al Jbawi verfasserin aut Mahwish verfasserin aut Ahmed H. El-Ghorab verfasserin aut Mohamed A. Abdelgawad verfasserin aut In International Journal of Food Properties Taylor & Francis Group, 2018 26(2023), 1, Seite 787-807 (DE-627)334376416 (DE-600)2057781-3 15322386 nnns volume:26 year:2023 number:1 pages:787-807 https://doi.org/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/article/d420daead2f94460b7b2f3de932f4f96 kostenfrei https://www.tandfonline.com/doi/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/toc/1094-2912 Journal toc kostenfrei https://doaj.org/toc/1532-2386 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2023 1 787-807
allfields_unstemmed	10.1080/10942912.2023.2184300 doi (DE-627)DOAJ088389626 (DE-599)DOAJd420daead2f94460b7b2f3de932f4f96 DE-627 ger DE-627 rakwb eng TX341-641 TP368-456 Zarina Mushtaq verfasserin aut Berberine: a comprehensive Approach to combat human maladies 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance. Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes Nutrition. Foods and food supply Food processing and manufacture Muhammad Imran verfasserin aut Farhan Saeed verfasserin aut Ali Imran verfasserin aut Shinawar Waseem Ali verfasserin aut Muhammad Shahbaz verfasserin aut Suliman A. Alsagaby verfasserin aut Yolanda Guerrero Sánchez verfasserin aut Maryam Umar verfasserin aut Muzzamal Hussain verfasserin aut Waleed Al abdulmonme verfasserin aut Entessar Al Jbawi verfasserin aut Mahwish verfasserin aut Ahmed H. El-Ghorab verfasserin aut Mohamed A. Abdelgawad verfasserin aut In International Journal of Food Properties Taylor & Francis Group, 2018 26(2023), 1, Seite 787-807 (DE-627)334376416 (DE-600)2057781-3 15322386 nnns volume:26 year:2023 number:1 pages:787-807 https://doi.org/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/article/d420daead2f94460b7b2f3de932f4f96 kostenfrei https://www.tandfonline.com/doi/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/toc/1094-2912 Journal toc kostenfrei https://doaj.org/toc/1532-2386 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2023 1 787-807
allfieldsGer	10.1080/10942912.2023.2184300 doi (DE-627)DOAJ088389626 (DE-599)DOAJd420daead2f94460b7b2f3de932f4f96 DE-627 ger DE-627 rakwb eng TX341-641 TP368-456 Zarina Mushtaq verfasserin aut Berberine: a comprehensive Approach to combat human maladies 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance. Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes Nutrition. Foods and food supply Food processing and manufacture Muhammad Imran verfasserin aut Farhan Saeed verfasserin aut Ali Imran verfasserin aut Shinawar Waseem Ali verfasserin aut Muhammad Shahbaz verfasserin aut Suliman A. Alsagaby verfasserin aut Yolanda Guerrero Sánchez verfasserin aut Maryam Umar verfasserin aut Muzzamal Hussain verfasserin aut Waleed Al abdulmonme verfasserin aut Entessar Al Jbawi verfasserin aut Mahwish verfasserin aut Ahmed H. El-Ghorab verfasserin aut Mohamed A. Abdelgawad verfasserin aut In International Journal of Food Properties Taylor & Francis Group, 2018 26(2023), 1, Seite 787-807 (DE-627)334376416 (DE-600)2057781-3 15322386 nnns volume:26 year:2023 number:1 pages:787-807 https://doi.org/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/article/d420daead2f94460b7b2f3de932f4f96 kostenfrei https://www.tandfonline.com/doi/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/toc/1094-2912 Journal toc kostenfrei https://doaj.org/toc/1532-2386 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2023 1 787-807
allfieldsSound	10.1080/10942912.2023.2184300 doi (DE-627)DOAJ088389626 (DE-599)DOAJd420daead2f94460b7b2f3de932f4f96 DE-627 ger DE-627 rakwb eng TX341-641 TP368-456 Zarina Mushtaq verfasserin aut Berberine: a comprehensive Approach to combat human maladies 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance. Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes Nutrition. Foods and food supply Food processing and manufacture Muhammad Imran verfasserin aut Farhan Saeed verfasserin aut Ali Imran verfasserin aut Shinawar Waseem Ali verfasserin aut Muhammad Shahbaz verfasserin aut Suliman A. Alsagaby verfasserin aut Yolanda Guerrero Sánchez verfasserin aut Maryam Umar verfasserin aut Muzzamal Hussain verfasserin aut Waleed Al abdulmonme verfasserin aut Entessar Al Jbawi verfasserin aut Mahwish verfasserin aut Ahmed H. El-Ghorab verfasserin aut Mohamed A. Abdelgawad verfasserin aut In International Journal of Food Properties Taylor & Francis Group, 2018 26(2023), 1, Seite 787-807 (DE-627)334376416 (DE-600)2057781-3 15322386 nnns volume:26 year:2023 number:1 pages:787-807 https://doi.org/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/article/d420daead2f94460b7b2f3de932f4f96 kostenfrei https://www.tandfonline.com/doi/10.1080/10942912.2023.2184300 kostenfrei https://doaj.org/toc/1094-2912 Journal toc kostenfrei https://doaj.org/toc/1532-2386 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2108 GBV_ILN_2111 GBV_ILN_2119 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 26 2023 1 787-807
language	English
source	In International Journal of Food Properties 26(2023), 1, Seite 787-807 volume:26 year:2023 number:1 pages:787-807
sourceStr	In International Journal of Food Properties 26(2023), 1, Seite 787-807 volume:26 year:2023 number:1 pages:787-807
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes Nutrition. Foods and food supply Food processing and manufacture
isfreeaccess_bool	true
container_title	International Journal of Food Properties
authorswithroles_txt_mv	Zarina Mushtaq @@aut@@ Muhammad Imran @@aut@@ Farhan Saeed @@aut@@ Ali Imran @@aut@@ Shinawar Waseem Ali @@aut@@ Muhammad Shahbaz @@aut@@ Suliman A. Alsagaby @@aut@@ Yolanda Guerrero Sánchez @@aut@@ Maryam Umar @@aut@@ Muzzamal Hussain @@aut@@ Waleed Al abdulmonme @@aut@@ Entessar Al Jbawi @@aut@@ Mahwish @@aut@@ Ahmed H. El-Ghorab @@aut@@ Mohamed A. Abdelgawad @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	334376416
id	DOAJ088389626
language_de	englisch
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author	Zarina Mushtaq
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topic_title	TX341-641 TP368-456 Berberine: a comprehensive Approach to combat human maladies Berberine Phytochemicals Cancer insurgence Molecular pathway Diabetes
topic	misc TX341-641 misc TP368-456 misc Berberine misc Phytochemicals misc Cancer insurgence misc Molecular pathway misc Diabetes misc Nutrition. Foods and food supply misc Food processing and manufacture
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title_sort	berberine: a comprehensive approach to combat human maladies
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title_auth	Berberine: a comprehensive Approach to combat human maladies
abstract	ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance.
abstractGer	ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance.
abstract_unstemmed	ABSTRACTBerberine is a metabolite of many medicinal plants. Chemically, berberine belongs to the isoquinoline alkaloids family. The roots of plants grown at lower elevations have a higher concentration of berberine as compared to plants grown at higher elevations. Berberine is a natural substance, which is now among the patent pharmaceuticals for reducing chronic disorders and malignancies. Berberine is also classified as a nutraceutical. Nutraceuticals have been associated with various health benefits via modifying microRNA (miR) expression systems, apoptosis, gene activity, chemical signals/pathways and activation of transcription factors thus aiding in the prevention from various ailments. The pharmacokinetic studies revealed that berberine is poorly absorbed via intestinal walls therefore, its concentration level is extremely low in body fluid. However, the quantity of berberine and its active derivatives in organs is higher as compared to blood as it stably present in tissues. Berberine has an effective role in the body as an anticancer, antidiabetic, antiobesity, antioxidant, antiinflammatory, neuroprotective, hepatoprotective, antiaging and cardioprotective agent. In this review, the therapeutic potentials of berberine are discussed to understand its nutraceutical importance.
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title_short	Berberine: a comprehensive Approach to combat human maladies
url	https://doi.org/10.1080/10942912.2023.2184300 https://doaj.org/article/d420daead2f94460b7b2f3de932f4f96 https://www.tandfonline.com/doi/10.1080/10942912.2023.2184300 https://doaj.org/toc/1094-2912 https://doaj.org/toc/1532-2386
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author2	Muhammad Imran Farhan Saeed Ali Imran Shinawar Waseem Ali Muhammad Shahbaz Suliman A. Alsagaby Yolanda Guerrero Sánchez Maryam Umar Muzzamal Hussain Waleed Al abdulmonme Entessar Al Jbawi Mahwish Ahmed H. El-Ghorab Mohamed A. Abdelgawad
author2Str	Muhammad Imran Farhan Saeed Ali Imran Shinawar Waseem Ali Muhammad Shahbaz Suliman A. Alsagaby Yolanda Guerrero Sánchez Maryam Umar Muzzamal Hussain Waleed Al abdulmonme Entessar Al Jbawi Mahwish Ahmed H. El-Ghorab Mohamed A. Abdelgawad
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