Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem

We report on the use of a lab-on-CMOS biosensor platform for quantitatively tracking the proliferation of RAW 264.7 murine Balb/c macrophages. We show that macrophage proliferation correlates linearly with an average capacitance growth factor resulting from capacitance measurements at a plurality of...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Kyle Smith [verfasserIn] Ching-Yi Lin [verfasserIn] Yann Gilpin [verfasserIn] Elizabeth Wayne [verfasserIn] Marc Dandin [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	CMOS biosensors capacitance lab-on-chip lab-on-CMOS model

Übergeordnetes Werk:	In: Frontiers in Bioengineering and Biotechnology - Frontiers Media S.A., 2014, 11(2023)
Übergeordnetes Werk:	volume:11 ; year:2023

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fbioe.2023.1159004

Katalog-ID:	DOAJ090405358

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allfieldsSound	10.3389/fbioe.2023.1159004 doi (DE-627)DOAJ090405358 (DE-599)DOAJ2758630dc74944c494fbe0a629d5300b DE-627 ger DE-627 rakwb eng TP248.13-248.65 Kyle Smith verfasserin aut Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We report on the use of a lab-on-CMOS biosensor platform for quantitatively tracking the proliferation of RAW 264.7 murine Balb/c macrophages. We show that macrophage proliferation correlates linearly with an average capacitance growth factor resulting from capacitance measurements at a plurality of electrodes dispersed in a sensing area of interest. We further show a temporal model that captures the cell number evolution in the area over long periods (e.g., 30 h). The model links the cell numbers and the average capacitance growth factor to describe the observed cell proliferation. CMOS biosensors capacitance lab-on-chip lab-on-CMOS model Biotechnology Ching-Yi Lin verfasserin aut Yann Gilpin verfasserin aut Elizabeth Wayne verfasserin aut Elizabeth Wayne verfasserin aut Marc Dandin verfasserin aut Marc Dandin verfasserin aut In Frontiers in Bioengineering and Biotechnology Frontiers Media S.A., 2014 11(2023) (DE-627)74950403X (DE-600)2719493-0 22964185 nnns volume:11 year:2023 https://doi.org/10.3389/fbioe.2023.1159004 kostenfrei https://doaj.org/article/2758630dc74944c494fbe0a629d5300b kostenfrei https://www.frontiersin.org/articles/10.3389/fbioe.2023.1159004/full kostenfrei https://doaj.org/toc/2296-4185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023
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callnumber-first	T - Technology
author	Kyle Smith
spellingShingle	Kyle Smith misc TP248.13-248.65 misc CMOS misc biosensors misc capacitance misc lab-on-chip misc lab-on-CMOS misc model misc Biotechnology Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem
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topic_title	TP248.13-248.65 Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem CMOS biosensors capacitance lab-on-chip lab-on-CMOS model
topic	misc TP248.13-248.65 misc CMOS misc biosensors misc capacitance misc lab-on-chip misc lab-on-CMOS misc model misc Biotechnology
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title	Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem
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title_full	Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem
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title_sort	measuring and modeling macrophage proliferation in a lab-on-cmos capacitance sensing microsystem
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title_auth	Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem
abstract	We report on the use of a lab-on-CMOS biosensor platform for quantitatively tracking the proliferation of RAW 264.7 murine Balb/c macrophages. We show that macrophage proliferation correlates linearly with an average capacitance growth factor resulting from capacitance measurements at a plurality of electrodes dispersed in a sensing area of interest. We further show a temporal model that captures the cell number evolution in the area over long periods (e.g., 30 h). The model links the cell numbers and the average capacitance growth factor to describe the observed cell proliferation.
abstractGer	We report on the use of a lab-on-CMOS biosensor platform for quantitatively tracking the proliferation of RAW 264.7 murine Balb/c macrophages. We show that macrophage proliferation correlates linearly with an average capacitance growth factor resulting from capacitance measurements at a plurality of electrodes dispersed in a sensing area of interest. We further show a temporal model that captures the cell number evolution in the area over long periods (e.g., 30 h). The model links the cell numbers and the average capacitance growth factor to describe the observed cell proliferation.
abstract_unstemmed	We report on the use of a lab-on-CMOS biosensor platform for quantitatively tracking the proliferation of RAW 264.7 murine Balb/c macrophages. We show that macrophage proliferation correlates linearly with an average capacitance growth factor resulting from capacitance measurements at a plurality of electrodes dispersed in a sensing area of interest. We further show a temporal model that captures the cell number evolution in the area over long periods (e.g., 30 h). The model links the cell numbers and the average capacitance growth factor to describe the observed cell proliferation.
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title_short	Measuring and modeling macrophage proliferation in a lab-on-CMOS capacitance sensing microsystem
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