Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes

Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with typ...
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Autor*in:	Chieh-Hua Lu [verfasserIn] Chien-Hsing Lee [verfasserIn] Li-Wei Wu [verfasserIn] Chun-Cheng Liao [verfasserIn] Sheng-Chiang Su [verfasserIn] Jhih-Syuan Liu [verfasserIn] Peng-Fei Li [verfasserIn] Chia-Luen Huang [verfasserIn] Li-Ju Ho [verfasserIn] Chien-Ming Lin [verfasserIn] Ming-Hsun Lin [verfasserIn] Chun-Yung Chang [verfasserIn] Yi-Chen Liu [verfasserIn] Chih-Ping Lin [verfasserIn] An-Che Cheng [verfasserIn] Feng-Chih Kuo [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition

Übergeordnetes Werk:	In: Diabetology & Metabolic Syndrome - BMC, 2010, 15(2023), 1, Seite 12
Übergeordnetes Werk:	volume:15 ; year:2023 ; number:1 ; pages:12

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/s13098-023-01087-w

Katalog-ID:	DOAJ090526775

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520			\|a Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM.
650		4	\|a Type 2 diabetes
650		4	\|a Grip strength
650		4	\|a Skinfold measurement
650		4	\|a Dual-energy x-ray absorptiometry
650		4	\|a Osteoporosis
650		4	\|a Body composition
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allfields	10.1186/s13098-023-01087-w doi (DE-627)DOAJ090526775 (DE-599)DOAJf73844e9dc474030b99a2c1f9c27c1da DE-627 ger DE-627 rakwb eng RC620-627 Chieh-Hua Lu verfasserin aut Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM. Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition Nutritional diseases. Deficiency diseases Chien-Hsing Lee verfasserin aut Li-Wei Wu verfasserin aut Chun-Cheng Liao verfasserin aut Sheng-Chiang Su verfasserin aut Jhih-Syuan Liu verfasserin aut Peng-Fei Li verfasserin aut Chia-Luen Huang verfasserin aut Li-Ju Ho verfasserin aut Chien-Ming Lin verfasserin aut Ming-Hsun Lin verfasserin aut Chun-Yung Chang verfasserin aut Yi-Chen Liu verfasserin aut Chih-Ping Lin verfasserin aut An-Che Cheng verfasserin aut Feng-Chih Kuo verfasserin aut In Diabetology & Metabolic Syndrome BMC, 2010 15(2023), 1, Seite 12 (DE-627)610606689 (DE-600)2518786-7 17585996 nnns volume:15 year:2023 number:1 pages:12 https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/article/f73844e9dc474030b99a2c1f9c27c1da kostenfrei https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/toc/1758-5996 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 1 12
spelling	10.1186/s13098-023-01087-w doi (DE-627)DOAJ090526775 (DE-599)DOAJf73844e9dc474030b99a2c1f9c27c1da DE-627 ger DE-627 rakwb eng RC620-627 Chieh-Hua Lu verfasserin aut Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM. Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition Nutritional diseases. Deficiency diseases Chien-Hsing Lee verfasserin aut Li-Wei Wu verfasserin aut Chun-Cheng Liao verfasserin aut Sheng-Chiang Su verfasserin aut Jhih-Syuan Liu verfasserin aut Peng-Fei Li verfasserin aut Chia-Luen Huang verfasserin aut Li-Ju Ho verfasserin aut Chien-Ming Lin verfasserin aut Ming-Hsun Lin verfasserin aut Chun-Yung Chang verfasserin aut Yi-Chen Liu verfasserin aut Chih-Ping Lin verfasserin aut An-Che Cheng verfasserin aut Feng-Chih Kuo verfasserin aut In Diabetology & Metabolic Syndrome BMC, 2010 15(2023), 1, Seite 12 (DE-627)610606689 (DE-600)2518786-7 17585996 nnns volume:15 year:2023 number:1 pages:12 https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/article/f73844e9dc474030b99a2c1f9c27c1da kostenfrei https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/toc/1758-5996 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 1 12
allfields_unstemmed	10.1186/s13098-023-01087-w doi (DE-627)DOAJ090526775 (DE-599)DOAJf73844e9dc474030b99a2c1f9c27c1da DE-627 ger DE-627 rakwb eng RC620-627 Chieh-Hua Lu verfasserin aut Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM. Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition Nutritional diseases. Deficiency diseases Chien-Hsing Lee verfasserin aut Li-Wei Wu verfasserin aut Chun-Cheng Liao verfasserin aut Sheng-Chiang Su verfasserin aut Jhih-Syuan Liu verfasserin aut Peng-Fei Li verfasserin aut Chia-Luen Huang verfasserin aut Li-Ju Ho verfasserin aut Chien-Ming Lin verfasserin aut Ming-Hsun Lin verfasserin aut Chun-Yung Chang verfasserin aut Yi-Chen Liu verfasserin aut Chih-Ping Lin verfasserin aut An-Che Cheng verfasserin aut Feng-Chih Kuo verfasserin aut In Diabetology & Metabolic Syndrome BMC, 2010 15(2023), 1, Seite 12 (DE-627)610606689 (DE-600)2518786-7 17585996 nnns volume:15 year:2023 number:1 pages:12 https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/article/f73844e9dc474030b99a2c1f9c27c1da kostenfrei https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/toc/1758-5996 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 1 12
allfieldsGer	10.1186/s13098-023-01087-w doi (DE-627)DOAJ090526775 (DE-599)DOAJf73844e9dc474030b99a2c1f9c27c1da DE-627 ger DE-627 rakwb eng RC620-627 Chieh-Hua Lu verfasserin aut Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM. Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition Nutritional diseases. Deficiency diseases Chien-Hsing Lee verfasserin aut Li-Wei Wu verfasserin aut Chun-Cheng Liao verfasserin aut Sheng-Chiang Su verfasserin aut Jhih-Syuan Liu verfasserin aut Peng-Fei Li verfasserin aut Chia-Luen Huang verfasserin aut Li-Ju Ho verfasserin aut Chien-Ming Lin verfasserin aut Ming-Hsun Lin verfasserin aut Chun-Yung Chang verfasserin aut Yi-Chen Liu verfasserin aut Chih-Ping Lin verfasserin aut An-Che Cheng verfasserin aut Feng-Chih Kuo verfasserin aut In Diabetology & Metabolic Syndrome BMC, 2010 15(2023), 1, Seite 12 (DE-627)610606689 (DE-600)2518786-7 17585996 nnns volume:15 year:2023 number:1 pages:12 https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/article/f73844e9dc474030b99a2c1f9c27c1da kostenfrei https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/toc/1758-5996 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 1 12
allfieldsSound	10.1186/s13098-023-01087-w doi (DE-627)DOAJ090526775 (DE-599)DOAJf73844e9dc474030b99a2c1f9c27c1da DE-627 ger DE-627 rakwb eng RC620-627 Chieh-Hua Lu verfasserin aut Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM. Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition Nutritional diseases. Deficiency diseases Chien-Hsing Lee verfasserin aut Li-Wei Wu verfasserin aut Chun-Cheng Liao verfasserin aut Sheng-Chiang Su verfasserin aut Jhih-Syuan Liu verfasserin aut Peng-Fei Li verfasserin aut Chia-Luen Huang verfasserin aut Li-Ju Ho verfasserin aut Chien-Ming Lin verfasserin aut Ming-Hsun Lin verfasserin aut Chun-Yung Chang verfasserin aut Yi-Chen Liu verfasserin aut Chih-Ping Lin verfasserin aut An-Che Cheng verfasserin aut Feng-Chih Kuo verfasserin aut In Diabetology & Metabolic Syndrome BMC, 2010 15(2023), 1, Seite 12 (DE-627)610606689 (DE-600)2518786-7 17585996 nnns volume:15 year:2023 number:1 pages:12 https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/article/f73844e9dc474030b99a2c1f9c27c1da kostenfrei https://doi.org/10.1186/s13098-023-01087-w kostenfrei https://doaj.org/toc/1758-5996 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2023 1 12
language	English
source	In Diabetology & Metabolic Syndrome 15(2023), 1, Seite 12 volume:15 year:2023 number:1 pages:12
sourceStr	In Diabetology & Metabolic Syndrome 15(2023), 1, Seite 12 volume:15 year:2023 number:1 pages:12
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition Nutritional diseases. Deficiency diseases
isfreeaccess_bool	true
container_title	Diabetology & Metabolic Syndrome
authorswithroles_txt_mv	Chieh-Hua Lu @@aut@@ Chien-Hsing Lee @@aut@@ Li-Wei Wu @@aut@@ Chun-Cheng Liao @@aut@@ Sheng-Chiang Su @@aut@@ Jhih-Syuan Liu @@aut@@ Peng-Fei Li @@aut@@ Chia-Luen Huang @@aut@@ Li-Ju Ho @@aut@@ Chien-Ming Lin @@aut@@ Ming-Hsun Lin @@aut@@ Chun-Yung Chang @@aut@@ Yi-Chen Liu @@aut@@ Chih-Ping Lin @@aut@@ An-Che Cheng @@aut@@ Feng-Chih Kuo @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	610606689
id	DOAJ090526775
language_de	englisch
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Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. 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callnumber-first	R - Medicine
author	Chieh-Hua Lu
spellingShingle	Chieh-Hua Lu misc RC620-627 misc Type 2 diabetes misc Grip strength misc Skinfold measurement misc Dual-energy x-ray absorptiometry misc Osteoporosis misc Body composition misc Nutritional diseases. Deficiency diseases Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes
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topic_title	RC620-627 Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes Type 2 diabetes Grip strength Skinfold measurement Dual-energy x-ray absorptiometry Osteoporosis Body composition
topic	misc RC620-627 misc Type 2 diabetes misc Grip strength misc Skinfold measurement misc Dual-energy x-ray absorptiometry misc Osteoporosis misc Body composition misc Nutritional diseases. Deficiency diseases
topic_unstemmed	misc RC620-627 misc Type 2 diabetes misc Grip strength misc Skinfold measurement misc Dual-energy x-ray absorptiometry misc Osteoporosis misc Body composition misc Nutritional diseases. Deficiency diseases
topic_browse	misc RC620-627 misc Type 2 diabetes misc Grip strength misc Skinfold measurement misc Dual-energy x-ray absorptiometry misc Osteoporosis misc Body composition misc Nutritional diseases. Deficiency diseases
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title	Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes
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title_full	Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes
author_sort	Chieh-Hua Lu
journal	Diabetology & Metabolic Syndrome
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author_browse	Chieh-Hua Lu Chien-Hsing Lee Li-Wei Wu Chun-Cheng Liao Sheng-Chiang Su Jhih-Syuan Liu Peng-Fei Li Chia-Luen Huang Li-Ju Ho Chien-Ming Lin Ming-Hsun Lin Chun-Yung Chang Yi-Chen Liu Chih-Ping Lin An-Che Cheng Feng-Chih Kuo
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author-letter	Chieh-Hua Lu
doi_str_mv	10.1186/s13098-023-01087-w
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title_sort	gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes
callnumber	RC620-627
title_auth	Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes
abstract	Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM.
abstractGer	Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM.
abstract_unstemmed	Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas is frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) with 7-site skinfold (SF) and dominant hand grip strength measurements among patients with type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 patients with T2DM (60 females and 43 males), aged between 50 and 80 years (median 68.0 years) were enrolled and 45 non-DM females were also included to compare with T2DM females. Results Our results revealed osteoporosis was negatively correlated with grip strength in both genders, negatively correlated with lean mass solely in males and negatively correlated with fat mass (particular the gynoid fat mass and thigh SF thickness) in females. Via performing multivariable stepwise logistic regression, we identified grip strength in both genders and thigh SF thickness in females as predictors for osteoporosis. Receiver operating characteristic curve analysis further disclosed 20.5 mm female thigh skinfold thickness, 18.1 kg female grip strength and 29.0 kg male grip strength as reasonable cutoff levels for predicting osteoporosis in the Taiwanese patients with T2DM. Conclusions Patients with T2DM presented gender-specific associations between osteoporosis, body composition and grip strength. Grip strength and thigh SF thickness might serve as predictors for detection of osteoporosis in patients with T2DM.
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title_short	Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes
url	https://doi.org/10.1186/s13098-023-01087-w https://doaj.org/article/f73844e9dc474030b99a2c1f9c27c1da https://doaj.org/toc/1758-5996
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author2	Chien-Hsing Lee Li-Wei Wu Chun-Cheng Liao Sheng-Chiang Su Jhih-Syuan Liu Peng-Fei Li Chia-Luen Huang Li-Ju Ho Chien-Ming Lin Ming-Hsun Lin Chun-Yung Chang Yi-Chen Liu Chih-Ping Lin An-Che Cheng Feng-Chih Kuo
author2Str	Chien-Hsing Lee Li-Wei Wu Chun-Cheng Liao Sheng-Chiang Su Jhih-Syuan Liu Peng-Fei Li Chia-Luen Huang Li-Ju Ho Chien-Ming Lin Ming-Hsun Lin Chun-Yung Chang Yi-Chen Liu Chih-Ping Lin An-Che Cheng Feng-Chih Kuo
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doi_str	10.1186/s13098-023-01087-w
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up_date	2024-07-03T15:16:22.323Z
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Gender-specific impacts of thigh skinfold thickness and grip strength for predicting osteoporosis in type 2 diabetes

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