Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria
Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, th...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Iorhen Ephraim Akase [verfasserIn] Patricia Eyanya Akintan [verfasserIn] Erereoghor Otrofanowei [verfasserIn] Oluwarotimi Bolaji Olopade [verfasserIn] Gbenga Olorunfemi [verfasserIn] Adefolarin Opawoye [verfasserIn] Felix M Alakaloko [verfasserIn] Uyiekpen Emmanuel Ima-Edomwonyi [verfasserIn] Yeside Olubunmi Akinbolagbe [verfasserIn] Osigwe Paul Agabi [verfasserIn] Danladi Abraham Nmadu [verfasserIn] Gbemileke O Akinbode [verfasserIn] Aramide C Olasope [verfasserIn] Adewale Ogundare [verfasserIn] Abiola Bukunmi Bolarinwa [verfasserIn] Oluwakemi Elizabeth Awojumobi-Otokiti [verfasserIn] Precious J Enajeroh [verfasserIn] Moses Karami [verfasserIn] Christopher Imokhuede Esezobor [verfasserIn] Yewande O Oshodi [verfasserIn] Oluwole Ayodeji Ayotunde [verfasserIn] Wasiu Lanre Adeyemo [verfasserIn] Christopher O Bode [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Journal of Clinical Sciences - Wolters Kluwer Medknow Publications, 2016, 20(2023), 1, Seite 15-21 |
|---|---|
| Übergeordnetes Werk: |
volume:20 ; year:2023 ; number:1 ; pages:15-21 |
| Links: |
Link aufrufen |
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| DOI / URN: |
10.4103/jcls.jcls_57_22 |
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| Katalog-ID: |
DOAJ090595556 |
|---|
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| 100 | 0 | |a Iorhen Ephraim Akase |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria |
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| 520 | |a Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. | ||
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| 650 | 4 | |a second wave | |
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| 700 | 0 | |a Patricia Eyanya Akintan |e verfasserin |4 aut | |
| 700 | 0 | |a Erereoghor Otrofanowei |e verfasserin |4 aut | |
| 700 | 0 | |a Oluwarotimi Bolaji Olopade |e verfasserin |4 aut | |
| 700 | 0 | |a Gbenga Olorunfemi |e verfasserin |4 aut | |
| 700 | 0 | |a Adefolarin Opawoye |e verfasserin |4 aut | |
| 700 | 0 | |a Felix M Alakaloko |e verfasserin |4 aut | |
| 700 | 0 | |a Uyiekpen Emmanuel Ima-Edomwonyi |e verfasserin |4 aut | |
| 700 | 0 | |a Yeside Olubunmi Akinbolagbe |e verfasserin |4 aut | |
| 700 | 0 | |a Osigwe Paul Agabi |e verfasserin |4 aut | |
| 700 | 0 | |a Danladi Abraham Nmadu |e verfasserin |4 aut | |
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| 700 | 0 | |a Aramide C Olasope |e verfasserin |4 aut | |
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| 700 | 0 | |a Abiola Bukunmi Bolarinwa |e verfasserin |4 aut | |
| 700 | 0 | |a Oluwakemi Elizabeth Awojumobi-Otokiti |e verfasserin |4 aut | |
| 700 | 0 | |a Precious J Enajeroh |e verfasserin |4 aut | |
| 700 | 0 | |a Moses Karami |e verfasserin |4 aut | |
| 700 | 0 | |a Christopher Imokhuede Esezobor |e verfasserin |4 aut | |
| 700 | 0 | |a Yewande O Oshodi |e verfasserin |4 aut | |
| 700 | 0 | |a Oluwole Ayodeji Ayotunde |e verfasserin |4 aut | |
| 700 | 0 | |a Wasiu Lanre Adeyemo |e verfasserin |4 aut | |
| 700 | 0 | |a Christopher O Bode |e verfasserin |4 aut | |
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10.4103/jcls.jcls_57_22 doi (DE-627)DOAJ090595556 (DE-599)DOAJ490b380d9d074126ab04b001a5e4385d DE-627 ger DE-627 rakwb eng R5-920 Iorhen Ephraim Akase verfasserin aut Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. covid-19 first wave lagos (nigeria) second wave Medicine (General) Patricia Eyanya Akintan verfasserin aut Erereoghor Otrofanowei verfasserin aut Oluwarotimi Bolaji Olopade verfasserin aut Gbenga Olorunfemi verfasserin aut Adefolarin Opawoye verfasserin aut Felix M Alakaloko verfasserin aut Uyiekpen Emmanuel Ima-Edomwonyi verfasserin aut Yeside Olubunmi Akinbolagbe verfasserin aut Osigwe Paul Agabi verfasserin aut Danladi Abraham Nmadu verfasserin aut Gbemileke O Akinbode verfasserin aut Aramide C Olasope verfasserin aut Adewale Ogundare verfasserin aut Abiola Bukunmi Bolarinwa verfasserin aut Oluwakemi Elizabeth Awojumobi-Otokiti verfasserin aut Precious J Enajeroh verfasserin aut Moses Karami verfasserin aut Christopher Imokhuede Esezobor verfasserin aut Yewande O Oshodi verfasserin aut Oluwole Ayodeji Ayotunde verfasserin aut Wasiu Lanre Adeyemo verfasserin aut Christopher O Bode verfasserin aut In Journal of Clinical Sciences Wolters Kluwer Medknow Publications, 2016 20(2023), 1, Seite 15-21 (DE-627)172536459X 24087408 nnns volume:20 year:2023 number:1 pages:15-21 https://doi.org/10.4103/jcls.jcls_57_22 kostenfrei https://doaj.org/article/490b380d9d074126ab04b001a5e4385d kostenfrei http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2023;volume=20;issue=1;spage=15;epage=21;aulast=Akase kostenfrei https://doaj.org/toc/2468-6859 Journal toc kostenfrei https://doaj.org/toc/2408-7408 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 1 15-21 |
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10.4103/jcls.jcls_57_22 doi (DE-627)DOAJ090595556 (DE-599)DOAJ490b380d9d074126ab04b001a5e4385d DE-627 ger DE-627 rakwb eng R5-920 Iorhen Ephraim Akase verfasserin aut Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. covid-19 first wave lagos (nigeria) second wave Medicine (General) Patricia Eyanya Akintan verfasserin aut Erereoghor Otrofanowei verfasserin aut Oluwarotimi Bolaji Olopade verfasserin aut Gbenga Olorunfemi verfasserin aut Adefolarin Opawoye verfasserin aut Felix M Alakaloko verfasserin aut Uyiekpen Emmanuel Ima-Edomwonyi verfasserin aut Yeside Olubunmi Akinbolagbe verfasserin aut Osigwe Paul Agabi verfasserin aut Danladi Abraham Nmadu verfasserin aut Gbemileke O Akinbode verfasserin aut Aramide C Olasope verfasserin aut Adewale Ogundare verfasserin aut Abiola Bukunmi Bolarinwa verfasserin aut Oluwakemi Elizabeth Awojumobi-Otokiti verfasserin aut Precious J Enajeroh verfasserin aut Moses Karami verfasserin aut Christopher Imokhuede Esezobor verfasserin aut Yewande O Oshodi verfasserin aut Oluwole Ayodeji Ayotunde verfasserin aut Wasiu Lanre Adeyemo verfasserin aut Christopher O Bode verfasserin aut In Journal of Clinical Sciences Wolters Kluwer Medknow Publications, 2016 20(2023), 1, Seite 15-21 (DE-627)172536459X 24087408 nnns volume:20 year:2023 number:1 pages:15-21 https://doi.org/10.4103/jcls.jcls_57_22 kostenfrei https://doaj.org/article/490b380d9d074126ab04b001a5e4385d kostenfrei http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2023;volume=20;issue=1;spage=15;epage=21;aulast=Akase kostenfrei https://doaj.org/toc/2468-6859 Journal toc kostenfrei https://doaj.org/toc/2408-7408 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 1 15-21 |
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10.4103/jcls.jcls_57_22 doi (DE-627)DOAJ090595556 (DE-599)DOAJ490b380d9d074126ab04b001a5e4385d DE-627 ger DE-627 rakwb eng R5-920 Iorhen Ephraim Akase verfasserin aut Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. covid-19 first wave lagos (nigeria) second wave Medicine (General) Patricia Eyanya Akintan verfasserin aut Erereoghor Otrofanowei verfasserin aut Oluwarotimi Bolaji Olopade verfasserin aut Gbenga Olorunfemi verfasserin aut Adefolarin Opawoye verfasserin aut Felix M Alakaloko verfasserin aut Uyiekpen Emmanuel Ima-Edomwonyi verfasserin aut Yeside Olubunmi Akinbolagbe verfasserin aut Osigwe Paul Agabi verfasserin aut Danladi Abraham Nmadu verfasserin aut Gbemileke O Akinbode verfasserin aut Aramide C Olasope verfasserin aut Adewale Ogundare verfasserin aut Abiola Bukunmi Bolarinwa verfasserin aut Oluwakemi Elizabeth Awojumobi-Otokiti verfasserin aut Precious J Enajeroh verfasserin aut Moses Karami verfasserin aut Christopher Imokhuede Esezobor verfasserin aut Yewande O Oshodi verfasserin aut Oluwole Ayodeji Ayotunde verfasserin aut Wasiu Lanre Adeyemo verfasserin aut Christopher O Bode verfasserin aut In Journal of Clinical Sciences Wolters Kluwer Medknow Publications, 2016 20(2023), 1, Seite 15-21 (DE-627)172536459X 24087408 nnns volume:20 year:2023 number:1 pages:15-21 https://doi.org/10.4103/jcls.jcls_57_22 kostenfrei https://doaj.org/article/490b380d9d074126ab04b001a5e4385d kostenfrei http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2023;volume=20;issue=1;spage=15;epage=21;aulast=Akase kostenfrei https://doaj.org/toc/2468-6859 Journal toc kostenfrei https://doaj.org/toc/2408-7408 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 1 15-21 |
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10.4103/jcls.jcls_57_22 doi (DE-627)DOAJ090595556 (DE-599)DOAJ490b380d9d074126ab04b001a5e4385d DE-627 ger DE-627 rakwb eng R5-920 Iorhen Ephraim Akase verfasserin aut Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. covid-19 first wave lagos (nigeria) second wave Medicine (General) Patricia Eyanya Akintan verfasserin aut Erereoghor Otrofanowei verfasserin aut Oluwarotimi Bolaji Olopade verfasserin aut Gbenga Olorunfemi verfasserin aut Adefolarin Opawoye verfasserin aut Felix M Alakaloko verfasserin aut Uyiekpen Emmanuel Ima-Edomwonyi verfasserin aut Yeside Olubunmi Akinbolagbe verfasserin aut Osigwe Paul Agabi verfasserin aut Danladi Abraham Nmadu verfasserin aut Gbemileke O Akinbode verfasserin aut Aramide C Olasope verfasserin aut Adewale Ogundare verfasserin aut Abiola Bukunmi Bolarinwa verfasserin aut Oluwakemi Elizabeth Awojumobi-Otokiti verfasserin aut Precious J Enajeroh verfasserin aut Moses Karami verfasserin aut Christopher Imokhuede Esezobor verfasserin aut Yewande O Oshodi verfasserin aut Oluwole Ayodeji Ayotunde verfasserin aut Wasiu Lanre Adeyemo verfasserin aut Christopher O Bode verfasserin aut In Journal of Clinical Sciences Wolters Kluwer Medknow Publications, 2016 20(2023), 1, Seite 15-21 (DE-627)172536459X 24087408 nnns volume:20 year:2023 number:1 pages:15-21 https://doi.org/10.4103/jcls.jcls_57_22 kostenfrei https://doaj.org/article/490b380d9d074126ab04b001a5e4385d kostenfrei http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2023;volume=20;issue=1;spage=15;epage=21;aulast=Akase kostenfrei https://doaj.org/toc/2468-6859 Journal toc kostenfrei https://doaj.org/toc/2408-7408 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 1 15-21 |
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10.4103/jcls.jcls_57_22 doi (DE-627)DOAJ090595556 (DE-599)DOAJ490b380d9d074126ab04b001a5e4385d DE-627 ger DE-627 rakwb eng R5-920 Iorhen Ephraim Akase verfasserin aut Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. covid-19 first wave lagos (nigeria) second wave Medicine (General) Patricia Eyanya Akintan verfasserin aut Erereoghor Otrofanowei verfasserin aut Oluwarotimi Bolaji Olopade verfasserin aut Gbenga Olorunfemi verfasserin aut Adefolarin Opawoye verfasserin aut Felix M Alakaloko verfasserin aut Uyiekpen Emmanuel Ima-Edomwonyi verfasserin aut Yeside Olubunmi Akinbolagbe verfasserin aut Osigwe Paul Agabi verfasserin aut Danladi Abraham Nmadu verfasserin aut Gbemileke O Akinbode verfasserin aut Aramide C Olasope verfasserin aut Adewale Ogundare verfasserin aut Abiola Bukunmi Bolarinwa verfasserin aut Oluwakemi Elizabeth Awojumobi-Otokiti verfasserin aut Precious J Enajeroh verfasserin aut Moses Karami verfasserin aut Christopher Imokhuede Esezobor verfasserin aut Yewande O Oshodi verfasserin aut Oluwole Ayodeji Ayotunde verfasserin aut Wasiu Lanre Adeyemo verfasserin aut Christopher O Bode verfasserin aut In Journal of Clinical Sciences Wolters Kluwer Medknow Publications, 2016 20(2023), 1, Seite 15-21 (DE-627)172536459X 24087408 nnns volume:20 year:2023 number:1 pages:15-21 https://doi.org/10.4103/jcls.jcls_57_22 kostenfrei https://doaj.org/article/490b380d9d074126ab04b001a5e4385d kostenfrei http://www.jcsjournal.org/article.asp?issn=2468-6859;year=2023;volume=20;issue=1;spage=15;epage=21;aulast=Akase kostenfrei https://doaj.org/toc/2468-6859 Journal toc kostenfrei https://doaj.org/toc/2408-7408 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2023 1 15-21 |
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Iorhen Ephraim Akase @@aut@@ Patricia Eyanya Akintan @@aut@@ Erereoghor Otrofanowei @@aut@@ Oluwarotimi Bolaji Olopade @@aut@@ Gbenga Olorunfemi @@aut@@ Adefolarin Opawoye @@aut@@ Felix M Alakaloko @@aut@@ Uyiekpen Emmanuel Ima-Edomwonyi @@aut@@ Yeside Olubunmi Akinbolagbe @@aut@@ Osigwe Paul Agabi @@aut@@ Danladi Abraham Nmadu @@aut@@ Gbemileke O Akinbode @@aut@@ Aramide C Olasope @@aut@@ Adewale Ogundare @@aut@@ Abiola Bukunmi Bolarinwa @@aut@@ Oluwakemi Elizabeth Awojumobi-Otokiti @@aut@@ Precious J Enajeroh @@aut@@ Moses Karami @@aut@@ Christopher Imokhuede Esezobor @@aut@@ Yewande O Oshodi @@aut@@ Oluwole Ayodeji Ayotunde @@aut@@ Wasiu Lanre Adeyemo @@aut@@ Christopher O Bode @@aut@@ |
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R5-920 Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria covid-19 first wave lagos (nigeria) second wave |
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Iorhen Ephraim Akase Patricia Eyanya Akintan Erereoghor Otrofanowei Oluwarotimi Bolaji Olopade Gbenga Olorunfemi Adefolarin Opawoye Felix M Alakaloko Uyiekpen Emmanuel Ima-Edomwonyi Yeside Olubunmi Akinbolagbe Osigwe Paul Agabi Danladi Abraham Nmadu Gbemileke O Akinbode Aramide C Olasope Adewale Ogundare Abiola Bukunmi Bolarinwa Oluwakemi Elizabeth Awojumobi-Otokiti Precious J Enajeroh Moses Karami Christopher Imokhuede Esezobor Yewande O Oshodi Oluwole Ayodeji Ayotunde Wasiu Lanre Adeyemo Christopher O Bode |
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clinical characteristics and outcome of patients admitted during the first and second waves of covid-19 pandemic at a tertiary hospital in lagos, nigeria |
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Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria |
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Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. |
| abstractGer |
Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. |
| abstract_unstemmed |
Introduction: Clinical data on the differences in presentation and outcome of admitted COVID-19 patients in Nigeria are limited. This study aimed to compare the first and second waves of the COVID-19 pandemic in a Tertiary Hospital in Lagos and describe the clinical differences between the waves, the severity of COVID-19, and the mortality differences. Methods: The study was a retrospective review of the medical records of all children and adults admitted to the Lagos University Teaching Hospital (LUTH) COVID-19 Isolation and Treatment Centre during the first wave (from April 2020 to October 2020) and second wave (from December 2020 to April 2021). The clinical characteristics (including COVID severity) and outcome among admitted patients during the two waves were compared. Results: Between April 2020 and April 2021, 602 patients were admitted to LUTH for COVID-19. Patients in the first wave were significantly younger (43 vs. 54.5 years), more in number (53.8% vs. 46.2%), and had a higher proportion of health-care workers than those in the second wave (14.5% vs. 6.5%). Comorbidities were present in more than half of the patients hospitalized for COVID-19 infection (51.0%). This proportion was much higher during the pandemic's second wave (41.7% vs. 61.9%, P < 0.001). The most common comorbidity found in hospitalized patients was hypertension (37.0%). Patients admitted during the second wave had shorter stays (11 vs. 7 days) and similar mortality rates (10.2% vs. 10.8%). Conclusion: The first and second waves had comparable mortality rates though patients in the first wave were younger and there were more healthcare providers in the cohort. Patients admitted to the second wave however had more comorbidities but shorter lengths of stay which may suggest a better understanding of the infection and better outcome. |
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Clinical characteristics and outcome of patients admitted during the first and second waves of COVID-19 pandemic at a Tertiary Hospital in Lagos, Nigeria |
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Patricia Eyanya Akintan Erereoghor Otrofanowei Oluwarotimi Bolaji Olopade Gbenga Olorunfemi Adefolarin Opawoye Felix M Alakaloko Uyiekpen Emmanuel Ima-Edomwonyi Yeside Olubunmi Akinbolagbe Osigwe Paul Agabi Danladi Abraham Nmadu Gbemileke O Akinbode Aramide C Olasope Adewale Ogundare Abiola Bukunmi Bolarinwa Oluwakemi Elizabeth Awojumobi-Otokiti Precious J Enajeroh Moses Karami Christopher Imokhuede Esezobor Yewande O Oshodi Oluwole Ayodeji Ayotunde Wasiu Lanre Adeyemo Christopher O Bode |
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