Management of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: Challenges and Opportunities
Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute...
Ausführliche Beschreibung
Autor*in: |
Doucet J [verfasserIn] Gourdy P [verfasserIn] Meyer L [verfasserIn] Benabdelmoumene N [verfasserIn] Bourdel-Marchasson I [verfasserIn] |
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Englisch |
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2023 |
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In: Clinical Interventions in Aging - Dove Medical Press, 2009, (2023), Seite 1687-1703 |
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year:2023 ; pages:1687-1703 |
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(DE-627)DOAJ090935373 (DE-599)DOAJ7199ebd392eb45a1936367d957df9316 DE-627 ger DE-627 rakwb eng RC952-954.6 Doucet J verfasserin aut Management of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: Challenges and Opportunities 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management type 2 diabetes older adults patient profiles management. Geriatrics Gourdy P verfasserin aut Meyer L verfasserin aut Benabdelmoumene N verfasserin aut Bourdel-Marchasson I verfasserin aut In Clinical Interventions in Aging Dove Medical Press, 2009 (2023), Seite 1687-1703 (DE-627)504104365 (DE-600)2212420-2 11781998 nnns year:2023 pages:1687-1703 https://doaj.org/article/7199ebd392eb45a1936367d957df9316 kostenfrei https://www.dovepress.com/management-of-glucose-lowering-therapy-in-older-adults-with-type-2-dia-peer-reviewed-fulltext-article-CIA kostenfrei https://doaj.org/toc/1178-1998 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2023 1687-1703 |
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(DE-627)DOAJ090935373 (DE-599)DOAJ7199ebd392eb45a1936367d957df9316 DE-627 ger DE-627 rakwb eng RC952-954.6 Doucet J verfasserin aut Management of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: Challenges and Opportunities 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management type 2 diabetes older adults patient profiles management. Geriatrics Gourdy P verfasserin aut Meyer L verfasserin aut Benabdelmoumene N verfasserin aut Bourdel-Marchasson I verfasserin aut In Clinical Interventions in Aging Dove Medical Press, 2009 (2023), Seite 1687-1703 (DE-627)504104365 (DE-600)2212420-2 11781998 nnns year:2023 pages:1687-1703 https://doaj.org/article/7199ebd392eb45a1936367d957df9316 kostenfrei https://www.dovepress.com/management-of-glucose-lowering-therapy-in-older-adults-with-type-2-dia-peer-reviewed-fulltext-article-CIA kostenfrei https://doaj.org/toc/1178-1998 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2023 1687-1703 |
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(DE-627)DOAJ090935373 (DE-599)DOAJ7199ebd392eb45a1936367d957df9316 DE-627 ger DE-627 rakwb eng RC952-954.6 Doucet J verfasserin aut Management of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: Challenges and Opportunities 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management type 2 diabetes older adults patient profiles management. Geriatrics Gourdy P verfasserin aut Meyer L verfasserin aut Benabdelmoumene N verfasserin aut Bourdel-Marchasson I verfasserin aut In Clinical Interventions in Aging Dove Medical Press, 2009 (2023), Seite 1687-1703 (DE-627)504104365 (DE-600)2212420-2 11781998 nnns year:2023 pages:1687-1703 https://doaj.org/article/7199ebd392eb45a1936367d957df9316 kostenfrei https://www.dovepress.com/management-of-glucose-lowering-therapy-in-older-adults-with-type-2-dia-peer-reviewed-fulltext-article-CIA kostenfrei https://doaj.org/toc/1178-1998 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2023 1687-1703 |
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(DE-627)DOAJ090935373 (DE-599)DOAJ7199ebd392eb45a1936367d957df9316 DE-627 ger DE-627 rakwb eng RC952-954.6 Doucet J verfasserin aut Management of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: Challenges and Opportunities 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management type 2 diabetes older adults patient profiles management. Geriatrics Gourdy P verfasserin aut Meyer L verfasserin aut Benabdelmoumene N verfasserin aut Bourdel-Marchasson I verfasserin aut In Clinical Interventions in Aging Dove Medical Press, 2009 (2023), Seite 1687-1703 (DE-627)504104365 (DE-600)2212420-2 11781998 nnns year:2023 pages:1687-1703 https://doaj.org/article/7199ebd392eb45a1936367d957df9316 kostenfrei https://www.dovepress.com/management-of-glucose-lowering-therapy-in-older-adults-with-type-2-dia-peer-reviewed-fulltext-article-CIA kostenfrei https://doaj.org/toc/1178-1998 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2023 1687-1703 |
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(DE-627)DOAJ090935373 (DE-599)DOAJ7199ebd392eb45a1936367d957df9316 DE-627 ger DE-627 rakwb eng RC952-954.6 Doucet J verfasserin aut Management of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: Challenges and Opportunities 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management type 2 diabetes older adults patient profiles management. Geriatrics Gourdy P verfasserin aut Meyer L verfasserin aut Benabdelmoumene N verfasserin aut Bourdel-Marchasson I verfasserin aut In Clinical Interventions in Aging Dove Medical Press, 2009 (2023), Seite 1687-1703 (DE-627)504104365 (DE-600)2212420-2 11781998 nnns year:2023 pages:1687-1703 https://doaj.org/article/7199ebd392eb45a1936367d957df9316 kostenfrei https://www.dovepress.com/management-of-glucose-lowering-therapy-in-older-adults-with-type-2-dia-peer-reviewed-fulltext-article-CIA kostenfrei https://doaj.org/toc/1178-1998 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2023 1687-1703 |
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Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management |
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Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management |
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Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ090935373</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240412230045.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240412s2023 xx |||||o 00| ||eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ090935373</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ7199ebd392eb45a1936367d957df9316</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC952-954.6</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Doucet J</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Management of Glucose-Lowering Therapy in Older Adults with Type 2 Diabetes: Challenges and Opportunities</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Jean Doucet,1 Pierre Gourdy,2,3 Laurent Meyer,4 Nabil Benabdelmoumene,5 Isabelle Bourdel-Marchasson6,7 1Department of Polyvalent Internal Medicine, Saint Julien Hospital, Rouen University Hospital, Rouen, France; 2Department of Diabetology, Toulouse University Hospital, Toulouse, France; 3Institute of Metabolic and Cardiovascular Diseases, UMR1297 INSERM/UT3, Toulouse University, Toulouse, France; 4Department of Endocrinology, Diabetes and Nutrition, University Hospital of Strasbourg, Strasbourg, France; 5Department of Internal Medicine and Geriatrics, University Hospital of Marseille, Marseille, France; 6CNRS, CRMSB, UMR 5536, University of Bordeaux, Bordeaux, France; 7University Hospital of Bordeaux, Bordeaux, FranceCorrespondence: Jean Doucet, Email jean.doucetchu-rouen.frAbstract: The population of older adults (≥ 65 years) with type 2 diabetes mellitus (T2DM) is diverse, encompassing individuals with varying functional capabilities, living arrangements, concomitant medical conditions, and life expectancies. Hence, their categorization into different patient profiles (ie, good health, intermediate health, poor health) may aid in clinical decision-making when establishing glycemic goals and pharmacological treatment strategies. Further granularity in assessing each patient profile through interdisciplinary collaboration may also add precision to therapeutic and monitoring decisions. In this review, we discuss with a multidisciplinary approach how to deliver the best benefit from advanced diabetes therapies and technologies to older adults with T2DM according to each patient profile. There remain however several areas that deserve further research in older adults with T2DM, including the efficacy and safety of continuous glucose monitoring and automated insulin delivery systems, the switch to once-weekly insulin, the effectiveness of multidisciplinary care models, and the use of supported telemedicine and remote blood glucose monitoring in the oldest-old (≥ 85 years) who particularly require the assistance of others.Keywords: type 2 diabetes, older adults, patient profiles, management</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">type 2 diabetes</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">older adults</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">patient profiles</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">management.</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield 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