Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity

The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These ins...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Gniazdo Dawid [verfasserIn] Sasal Wanesa [verfasserIn] Omelaniuk Aleksandra [verfasserIn] Brudz Weronika [verfasserIn] Kaca Wiesław [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch ; Polnisch

Erschienen:	2023

Schlagwörter:	galleria mellonella microbial pathogenesis model

Übergeordnetes Werk:	In: Postępy Mikrobiologii - Sciendo, 2020, 62(2023), 3-4, Seite 173-182
Übergeordnetes Werk:	volume:62 ; year:2023 ; number:3-4 ; pages:173-182

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.2478/am-2023-0015

Katalog-ID:	DOAJ091111048

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allfields	10.2478/am-2023-0015 doi (DE-627)DOAJ091111048 (DE-599)DOAJ53c47caf5c4144b9b66771f074db068a DE-627 ger DE-627 rakwb eng pol QR1-502 Gniazdo Dawid verfasserin aut Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune system and a nonspecific immune response similar to that of humans, making them a valuable model for studying pathogen-host interactions. Furthermore, using this model, it is possible to test the efficacy of various chemical compounds or natural substances that show antimicrobial activity. In this literature review, we provide a comprehensive overview of recent studies of the use of G. mellonella in virulence analyses and as a platform for testing the efficacy of new drugs. galleria mellonella microbial pathogenesis model Microbiology Sasal Wanesa verfasserin aut Omelaniuk Aleksandra verfasserin aut Brudz Weronika verfasserin aut Kaca Wiesław verfasserin aut In Postępy Mikrobiologii Sciendo, 2020 62(2023), 3-4, Seite 173-182 (DE-627)511640978 (DE-600)2234082-8 25453149 nnns volume:62 year:2023 number:3-4 pages:173-182 https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/article/53c47caf5c4144b9b66771f074db068a kostenfrei https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/toc/2545-3149 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2023 3-4 173-182
spelling	10.2478/am-2023-0015 doi (DE-627)DOAJ091111048 (DE-599)DOAJ53c47caf5c4144b9b66771f074db068a DE-627 ger DE-627 rakwb eng pol QR1-502 Gniazdo Dawid verfasserin aut Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune system and a nonspecific immune response similar to that of humans, making them a valuable model for studying pathogen-host interactions. Furthermore, using this model, it is possible to test the efficacy of various chemical compounds or natural substances that show antimicrobial activity. In this literature review, we provide a comprehensive overview of recent studies of the use of G. mellonella in virulence analyses and as a platform for testing the efficacy of new drugs. galleria mellonella microbial pathogenesis model Microbiology Sasal Wanesa verfasserin aut Omelaniuk Aleksandra verfasserin aut Brudz Weronika verfasserin aut Kaca Wiesław verfasserin aut In Postępy Mikrobiologii Sciendo, 2020 62(2023), 3-4, Seite 173-182 (DE-627)511640978 (DE-600)2234082-8 25453149 nnns volume:62 year:2023 number:3-4 pages:173-182 https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/article/53c47caf5c4144b9b66771f074db068a kostenfrei https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/toc/2545-3149 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2023 3-4 173-182
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allfieldsGer	10.2478/am-2023-0015 doi (DE-627)DOAJ091111048 (DE-599)DOAJ53c47caf5c4144b9b66771f074db068a DE-627 ger DE-627 rakwb eng pol QR1-502 Gniazdo Dawid verfasserin aut Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune system and a nonspecific immune response similar to that of humans, making them a valuable model for studying pathogen-host interactions. Furthermore, using this model, it is possible to test the efficacy of various chemical compounds or natural substances that show antimicrobial activity. In this literature review, we provide a comprehensive overview of recent studies of the use of G. mellonella in virulence analyses and as a platform for testing the efficacy of new drugs. galleria mellonella microbial pathogenesis model Microbiology Sasal Wanesa verfasserin aut Omelaniuk Aleksandra verfasserin aut Brudz Weronika verfasserin aut Kaca Wiesław verfasserin aut In Postępy Mikrobiologii Sciendo, 2020 62(2023), 3-4, Seite 173-182 (DE-627)511640978 (DE-600)2234082-8 25453149 nnns volume:62 year:2023 number:3-4 pages:173-182 https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/article/53c47caf5c4144b9b66771f074db068a kostenfrei https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/toc/2545-3149 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2023 3-4 173-182
allfieldsSound	10.2478/am-2023-0015 doi (DE-627)DOAJ091111048 (DE-599)DOAJ53c47caf5c4144b9b66771f074db068a DE-627 ger DE-627 rakwb eng pol QR1-502 Gniazdo Dawid verfasserin aut Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune system and a nonspecific immune response similar to that of humans, making them a valuable model for studying pathogen-host interactions. Furthermore, using this model, it is possible to test the efficacy of various chemical compounds or natural substances that show antimicrobial activity. In this literature review, we provide a comprehensive overview of recent studies of the use of G. mellonella in virulence analyses and as a platform for testing the efficacy of new drugs. galleria mellonella microbial pathogenesis model Microbiology Sasal Wanesa verfasserin aut Omelaniuk Aleksandra verfasserin aut Brudz Weronika verfasserin aut Kaca Wiesław verfasserin aut In Postępy Mikrobiologii Sciendo, 2020 62(2023), 3-4, Seite 173-182 (DE-627)511640978 (DE-600)2234082-8 25453149 nnns volume:62 year:2023 number:3-4 pages:173-182 https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/article/53c47caf5c4144b9b66771f074db068a kostenfrei https://doi.org/10.2478/am-2023-0015 kostenfrei https://doaj.org/toc/2545-3149 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2023 3-4 173-182
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title	Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity
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title_full	Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity
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title_sort	galleria mellonella larvae as an in vitro model for testing microbial pathogenicity
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title_auth	Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity
abstract	The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune system and a nonspecific immune response similar to that of humans, making them a valuable model for studying pathogen-host interactions. Furthermore, using this model, it is possible to test the efficacy of various chemical compounds or natural substances that show antimicrobial activity. In this literature review, we provide a comprehensive overview of recent studies of the use of G. mellonella in virulence analyses and as a platform for testing the efficacy of new drugs.
abstractGer	The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune system and a nonspecific immune response similar to that of humans, making them a valuable model for studying pathogen-host interactions. Furthermore, using this model, it is possible to test the efficacy of various chemical compounds or natural substances that show antimicrobial activity. In this literature review, we provide a comprehensive overview of recent studies of the use of G. mellonella in virulence analyses and as a platform for testing the efficacy of new drugs.
abstract_unstemmed	The larvae of the insect Galleria mellonella have gained wide acceptance as an in vivo model for the study of virulence in Gram-negative and Gram-positive bacteria and fungi. Importantly, G. mellonella offers an alternative, low-cost, and ethically acceptable method of assessing pathogens. These insects have a number of advantages, including ease of breeding, a rapid developmental cycle, low maintenance costs, and ease of experimental manipulation. Most importantly, G. mellonella larvae have a complete immune system and a nonspecific immune response similar to that of humans, making them a valuable model for studying pathogen-host interactions. Furthermore, using this model, it is possible to test the efficacy of various chemical compounds or natural substances that show antimicrobial activity. In this literature review, we provide a comprehensive overview of recent studies of the use of G. mellonella in virulence analyses and as a platform for testing the efficacy of new drugs.
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title_short	Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity
url	https://doi.org/10.2478/am-2023-0015 https://doaj.org/article/53c47caf5c4144b9b66771f074db068a https://doaj.org/toc/2545-3149
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Galleria Mellonella Larvae as an In vitro Model for Testing Microbial Pathogenicity

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