Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)

Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Linda A. J. Hendricks [verfasserIn] Katja C. J. Verbeek [verfasserIn] Janneke H. M. Schuurs-Hoeijmakers [verfasserIn] Arjen R. Mensenkamp [verfasserIn] Hilde Brems [verfasserIn] Robin de Putter [verfasserIn] Violetta C. Anastasiadou [verfasserIn] Marie-Charlotte Villy [verfasserIn] Arne Jahn [verfasserIn] Verena Steinke-Lange [verfasserIn] Margherita Baldassarri [verfasserIn] Arvids Irmejs [verfasserIn] Mirjam M. de Jong [verfasserIn] Thera P. Links [verfasserIn] Edward M. Leter [verfasserIn] Daniëlle G. M. Bosch [verfasserIn] Hildegunn Høberg-Vetti [verfasserIn] Marianne Tveit Haavind [verfasserIn] Kjersti Jørgensen [verfasserIn] Lovise Mæhle [verfasserIn] Ana Blatnik [verfasserIn] Joan Brunet [verfasserIn] Esther Darder [verfasserIn] Emma Tham [verfasserIn] Nicoline Hoogerbrugge [verfasserIn] Janet R. Vos [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple

Übergeordnetes Werk:	In: Cancers - MDPI AG, 2010, 16(2024), 5, p 953
Übergeordnetes Werk:	volume:16 ; year:2024 ; number:5, p 953

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/cancers16050953

Katalog-ID:	DOAJ091272653

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ091272653
003	DE-627
005	20240413232928.0
007	cr uuu---uuuuu
008	240412s2024 xx \|\|\|\|\|o 00\| \|\|eng c
024	7		\|a 10.3390/cancers16050953 \|2 doi
035			\|a (DE-627)DOAJ091272653
035			\|a (DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
050		0	\|a RC254-282
100	0		\|a Linda A. J. Hendricks \|e verfasserin \|4 aut
245	1	0	\|a Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)
264		1	\|c 2024
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important.
650		4	\|a alcohol drinking
650		4	\|a body mass index
650		4	\|a breast neoplasm
650		4	\|a exercise
650		4	\|a hamartoma syndrome
650		4	\|a multiple
653		0	\|a Neoplasms. Tumors. Oncology. Including cancer and carcinogens
700	0		\|a Katja C. J. Verbeek \|e verfasserin \|4 aut
700	0		\|a Janneke H. M. Schuurs-Hoeijmakers \|e verfasserin \|4 aut
700	0		\|a Arjen R. Mensenkamp \|e verfasserin \|4 aut
700	0		\|a Hilde Brems \|e verfasserin \|4 aut
700	0		\|a Robin de Putter \|e verfasserin \|4 aut
700	0		\|a Violetta C. Anastasiadou \|e verfasserin \|4 aut
700	0		\|a Marie-Charlotte Villy \|e verfasserin \|4 aut
700	0		\|a Arne Jahn \|e verfasserin \|4 aut
700	0		\|a Verena Steinke-Lange \|e verfasserin \|4 aut
700	0		\|a Margherita Baldassarri \|e verfasserin \|4 aut
700	0		\|a Arvids Irmejs \|e verfasserin \|4 aut
700	0		\|a Mirjam M. de Jong \|e verfasserin \|4 aut
700	0		\|a Thera P. Links \|e verfasserin \|4 aut
700	0		\|a Edward M. Leter \|e verfasserin \|4 aut
700	0		\|a Daniëlle G. M. Bosch \|e verfasserin \|4 aut
700	0		\|a Hildegunn Høberg-Vetti \|e verfasserin \|4 aut
700	0		\|a Marianne Tveit Haavind \|e verfasserin \|4 aut
700	0		\|a Kjersti Jørgensen \|e verfasserin \|4 aut
700	0		\|a Lovise Mæhle \|e verfasserin \|4 aut
700	0		\|a Ana Blatnik \|e verfasserin \|4 aut
700	0		\|a Joan Brunet \|e verfasserin \|4 aut
700	0		\|a Esther Darder \|e verfasserin \|4 aut
700	0		\|a Emma Tham \|e verfasserin \|4 aut
700	0		\|a Nicoline Hoogerbrugge \|e verfasserin \|4 aut
700	0		\|a Janet R. Vos \|e verfasserin \|4 aut
773	0	8	\|i In \|t Cancers \|d MDPI AG, 2010 \|g 16(2024), 5, p 953 \|w (DE-627)614095670 \|w (DE-600)2527080-1 \|x 20726694 \|7 nnns
773	1	8	\|g volume:16 \|g year:2024 \|g number:5, p 953
856	4	0	\|u https://doi.org/10.3390/cancers16050953 \|z kostenfrei
856	4	0	\|u https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8 \|z kostenfrei
856	4	0	\|u https://www.mdpi.com/2072-6694/16/5/953 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/2072-6694 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 16 \|j 2024 \|e 5, p 953

Indexfelder

author_variant	l a j h lajh k c j v kcjv j h m s h jhmsh a r m arm h b hb r d p rdp v c a vca m c v mcv a j aj v s l vsl m b mb a i ai m m d j mmdj t p l tpl e m l eml d g m b dgmb h h v hhv m t h mth k j kj l m lm a b ab j b jb e d ed e t et n h nh j r v jrv
matchkey_str	article:20726694:2024----::ietlfcosnbescneifmlsihtnaat
hierarchy_sort_str	2024
callnumber-subject-code	RC
publishDate	2024
allfields	10.3390/cancers16050953 doi (DE-627)DOAJ091272653 (DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8 DE-627 ger DE-627 rakwb eng RC254-282 Linda A. J. Hendricks verfasserin aut Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important. alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple Neoplasms. Tumors. Oncology. Including cancer and carcinogens Katja C. J. Verbeek verfasserin aut Janneke H. M. Schuurs-Hoeijmakers verfasserin aut Arjen R. Mensenkamp verfasserin aut Hilde Brems verfasserin aut Robin de Putter verfasserin aut Violetta C. Anastasiadou verfasserin aut Marie-Charlotte Villy verfasserin aut Arne Jahn verfasserin aut Verena Steinke-Lange verfasserin aut Margherita Baldassarri verfasserin aut Arvids Irmejs verfasserin aut Mirjam M. de Jong verfasserin aut Thera P. Links verfasserin aut Edward M. Leter verfasserin aut Daniëlle G. M. Bosch verfasserin aut Hildegunn Høberg-Vetti verfasserin aut Marianne Tveit Haavind verfasserin aut Kjersti Jørgensen verfasserin aut Lovise Mæhle verfasserin aut Ana Blatnik verfasserin aut Joan Brunet verfasserin aut Esther Darder verfasserin aut Emma Tham verfasserin aut Nicoline Hoogerbrugge verfasserin aut Janet R. Vos verfasserin aut In Cancers MDPI AG, 2010 16(2024), 5, p 953 (DE-627)614095670 (DE-600)2527080-1 20726694 nnns volume:16 year:2024 number:5, p 953 https://doi.org/10.3390/cancers16050953 kostenfrei https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8 kostenfrei https://www.mdpi.com/2072-6694/16/5/953 kostenfrei https://doaj.org/toc/2072-6694 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2024 5, p 953
spelling	10.3390/cancers16050953 doi (DE-627)DOAJ091272653 (DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8 DE-627 ger DE-627 rakwb eng RC254-282 Linda A. J. Hendricks verfasserin aut Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important. alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple Neoplasms. Tumors. Oncology. Including cancer and carcinogens Katja C. J. Verbeek verfasserin aut Janneke H. M. Schuurs-Hoeijmakers verfasserin aut Arjen R. Mensenkamp verfasserin aut Hilde Brems verfasserin aut Robin de Putter verfasserin aut Violetta C. Anastasiadou verfasserin aut Marie-Charlotte Villy verfasserin aut Arne Jahn verfasserin aut Verena Steinke-Lange verfasserin aut Margherita Baldassarri verfasserin aut Arvids Irmejs verfasserin aut Mirjam M. de Jong verfasserin aut Thera P. Links verfasserin aut Edward M. Leter verfasserin aut Daniëlle G. M. Bosch verfasserin aut Hildegunn Høberg-Vetti verfasserin aut Marianne Tveit Haavind verfasserin aut Kjersti Jørgensen verfasserin aut Lovise Mæhle verfasserin aut Ana Blatnik verfasserin aut Joan Brunet verfasserin aut Esther Darder verfasserin aut Emma Tham verfasserin aut Nicoline Hoogerbrugge verfasserin aut Janet R. Vos verfasserin aut In Cancers MDPI AG, 2010 16(2024), 5, p 953 (DE-627)614095670 (DE-600)2527080-1 20726694 nnns volume:16 year:2024 number:5, p 953 https://doi.org/10.3390/cancers16050953 kostenfrei https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8 kostenfrei https://www.mdpi.com/2072-6694/16/5/953 kostenfrei https://doaj.org/toc/2072-6694 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2024 5, p 953
allfields_unstemmed	10.3390/cancers16050953 doi (DE-627)DOAJ091272653 (DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8 DE-627 ger DE-627 rakwb eng RC254-282 Linda A. J. Hendricks verfasserin aut Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important. alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple Neoplasms. Tumors. Oncology. Including cancer and carcinogens Katja C. J. Verbeek verfasserin aut Janneke H. M. Schuurs-Hoeijmakers verfasserin aut Arjen R. Mensenkamp verfasserin aut Hilde Brems verfasserin aut Robin de Putter verfasserin aut Violetta C. Anastasiadou verfasserin aut Marie-Charlotte Villy verfasserin aut Arne Jahn verfasserin aut Verena Steinke-Lange verfasserin aut Margherita Baldassarri verfasserin aut Arvids Irmejs verfasserin aut Mirjam M. de Jong verfasserin aut Thera P. Links verfasserin aut Edward M. Leter verfasserin aut Daniëlle G. M. Bosch verfasserin aut Hildegunn Høberg-Vetti verfasserin aut Marianne Tveit Haavind verfasserin aut Kjersti Jørgensen verfasserin aut Lovise Mæhle verfasserin aut Ana Blatnik verfasserin aut Joan Brunet verfasserin aut Esther Darder verfasserin aut Emma Tham verfasserin aut Nicoline Hoogerbrugge verfasserin aut Janet R. Vos verfasserin aut In Cancers MDPI AG, 2010 16(2024), 5, p 953 (DE-627)614095670 (DE-600)2527080-1 20726694 nnns volume:16 year:2024 number:5, p 953 https://doi.org/10.3390/cancers16050953 kostenfrei https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8 kostenfrei https://www.mdpi.com/2072-6694/16/5/953 kostenfrei https://doaj.org/toc/2072-6694 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2024 5, p 953
allfieldsGer	10.3390/cancers16050953 doi (DE-627)DOAJ091272653 (DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8 DE-627 ger DE-627 rakwb eng RC254-282 Linda A. J. Hendricks verfasserin aut Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important. alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple Neoplasms. Tumors. Oncology. Including cancer and carcinogens Katja C. J. Verbeek verfasserin aut Janneke H. M. Schuurs-Hoeijmakers verfasserin aut Arjen R. Mensenkamp verfasserin aut Hilde Brems verfasserin aut Robin de Putter verfasserin aut Violetta C. Anastasiadou verfasserin aut Marie-Charlotte Villy verfasserin aut Arne Jahn verfasserin aut Verena Steinke-Lange verfasserin aut Margherita Baldassarri verfasserin aut Arvids Irmejs verfasserin aut Mirjam M. de Jong verfasserin aut Thera P. Links verfasserin aut Edward M. Leter verfasserin aut Daniëlle G. M. Bosch verfasserin aut Hildegunn Høberg-Vetti verfasserin aut Marianne Tveit Haavind verfasserin aut Kjersti Jørgensen verfasserin aut Lovise Mæhle verfasserin aut Ana Blatnik verfasserin aut Joan Brunet verfasserin aut Esther Darder verfasserin aut Emma Tham verfasserin aut Nicoline Hoogerbrugge verfasserin aut Janet R. Vos verfasserin aut In Cancers MDPI AG, 2010 16(2024), 5, p 953 (DE-627)614095670 (DE-600)2527080-1 20726694 nnns volume:16 year:2024 number:5, p 953 https://doi.org/10.3390/cancers16050953 kostenfrei https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8 kostenfrei https://www.mdpi.com/2072-6694/16/5/953 kostenfrei https://doaj.org/toc/2072-6694 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2024 5, p 953
allfieldsSound	10.3390/cancers16050953 doi (DE-627)DOAJ091272653 (DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8 DE-627 ger DE-627 rakwb eng RC254-282 Linda A. J. Hendricks verfasserin aut Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important. alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple Neoplasms. Tumors. Oncology. Including cancer and carcinogens Katja C. J. Verbeek verfasserin aut Janneke H. M. Schuurs-Hoeijmakers verfasserin aut Arjen R. Mensenkamp verfasserin aut Hilde Brems verfasserin aut Robin de Putter verfasserin aut Violetta C. Anastasiadou verfasserin aut Marie-Charlotte Villy verfasserin aut Arne Jahn verfasserin aut Verena Steinke-Lange verfasserin aut Margherita Baldassarri verfasserin aut Arvids Irmejs verfasserin aut Mirjam M. de Jong verfasserin aut Thera P. Links verfasserin aut Edward M. Leter verfasserin aut Daniëlle G. M. Bosch verfasserin aut Hildegunn Høberg-Vetti verfasserin aut Marianne Tveit Haavind verfasserin aut Kjersti Jørgensen verfasserin aut Lovise Mæhle verfasserin aut Ana Blatnik verfasserin aut Joan Brunet verfasserin aut Esther Darder verfasserin aut Emma Tham verfasserin aut Nicoline Hoogerbrugge verfasserin aut Janet R. Vos verfasserin aut In Cancers MDPI AG, 2010 16(2024), 5, p 953 (DE-627)614095670 (DE-600)2527080-1 20726694 nnns volume:16 year:2024 number:5, p 953 https://doi.org/10.3390/cancers16050953 kostenfrei https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8 kostenfrei https://www.mdpi.com/2072-6694/16/5/953 kostenfrei https://doaj.org/toc/2072-6694 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2024 5, p 953
language	English
source	In Cancers 16(2024), 5, p 953 volume:16 year:2024 number:5, p 953
sourceStr	In Cancers 16(2024), 5, p 953 volume:16 year:2024 number:5, p 953
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple Neoplasms. Tumors. Oncology. Including cancer and carcinogens
isfreeaccess_bool	true
container_title	Cancers
authorswithroles_txt_mv	Linda A. J. Hendricks @@aut@@ Katja C. J. Verbeek @@aut@@ Janneke H. M. Schuurs-Hoeijmakers @@aut@@ Arjen R. Mensenkamp @@aut@@ Hilde Brems @@aut@@ Robin de Putter @@aut@@ Violetta C. Anastasiadou @@aut@@ Marie-Charlotte Villy @@aut@@ Arne Jahn @@aut@@ Verena Steinke-Lange @@aut@@ Margherita Baldassarri @@aut@@ Arvids Irmejs @@aut@@ Mirjam M. de Jong @@aut@@ Thera P. Links @@aut@@ Edward M. Leter @@aut@@ Daniëlle G. M. Bosch @@aut@@ Hildegunn Høberg-Vetti @@aut@@ Marianne Tveit Haavind @@aut@@ Kjersti Jørgensen @@aut@@ Lovise Mæhle @@aut@@ Ana Blatnik @@aut@@ Joan Brunet @@aut@@ Esther Darder @@aut@@ Emma Tham @@aut@@ Nicoline Hoogerbrugge @@aut@@ Janet R. Vos @@aut@@
publishDateDaySort_date	2024-01-01T00:00:00Z
hierarchy_top_id	614095670
id	DOAJ091272653
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ091272653</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413232928.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240412s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/cancers16050953</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ091272653</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC254-282</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Linda A. J. Hendricks</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">alcohol drinking</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">body mass index</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">breast neoplasm</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">exercise</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">hamartoma syndrome</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">multiple</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neoplasms. Tumors. Oncology. Including cancer and carcinogens</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Katja C. J. Verbeek</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Janneke H. M. Schuurs-Hoeijmakers</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Arjen R. Mensenkamp</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hilde Brems</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Robin de Putter</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Violetta C. Anastasiadou</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marie-Charlotte Villy</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Arne Jahn</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Verena Steinke-Lange</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Margherita Baldassarri</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Arvids Irmejs</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mirjam M. de Jong</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Thera P. Links</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Edward M. Leter</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Daniëlle G. M. Bosch</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hildegunn Høberg-Vetti</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marianne Tveit Haavind</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kjersti Jørgensen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Lovise Mæhle</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ana Blatnik</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Joan Brunet</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Esther Darder</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Emma Tham</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nicoline Hoogerbrugge</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Janet R. Vos</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Cancers</subfield><subfield code="d">MDPI AG, 2010</subfield><subfield code="g">16(2024), 5, p 953</subfield><subfield code="w">(DE-627)614095670</subfield><subfield code="w">(DE-600)2527080-1</subfield><subfield code="x">20726694</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:16</subfield><subfield code="g">year:2024</subfield><subfield code="g">number:5, p 953</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/cancers16050953</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/2072-6694/16/5/953</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2072-6694</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">16</subfield><subfield code="j">2024</subfield><subfield code="e">5, p 953</subfield></datafield></record></collection>
callnumber-first	R - Medicine
author	Linda A. J. Hendricks
spellingShingle	Linda A. J. Hendricks misc RC254-282 misc alcohol drinking misc body mass index misc breast neoplasm misc exercise misc hamartoma syndrome misc multiple misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)
authorStr	Linda A. J. Hendricks
ppnlink_with_tag_str_mv	@@773@@(DE-627)614095670
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	RC254-282
illustrated	Not Illustrated
issn	20726694
topic_title	RC254-282 Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS) alcohol drinking body mass index breast neoplasm exercise hamartoma syndrome multiple
topic	misc RC254-282 misc alcohol drinking misc body mass index misc breast neoplasm misc exercise misc hamartoma syndrome misc multiple misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RC254-282 misc alcohol drinking misc body mass index misc breast neoplasm misc exercise misc hamartoma syndrome misc multiple misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_browse	misc RC254-282 misc alcohol drinking misc body mass index misc breast neoplasm misc exercise misc hamartoma syndrome misc multiple misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Cancers
hierarchy_parent_id	614095670
hierarchy_top_title	Cancers
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)614095670 (DE-600)2527080-1
title	Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)
ctrlnum	(DE-627)DOAJ091272653 (DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8
title_full	Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)
author_sort	Linda A. J. Hendricks
journal	Cancers
journalStr	Cancers
callnumber-first-code	R
lang_code	eng
isOA_bool	true
recordtype	marc
publishDateSort	2024
contenttype_str_mv	txt
author_browse	Linda A. J. Hendricks Katja C. J. Verbeek Janneke H. M. Schuurs-Hoeijmakers Arjen R. Mensenkamp Hilde Brems Robin de Putter Violetta C. Anastasiadou Marie-Charlotte Villy Arne Jahn Verena Steinke-Lange Margherita Baldassarri Arvids Irmejs Mirjam M. de Jong Thera P. Links Edward M. Leter Daniëlle G. M. Bosch Hildegunn Høberg-Vetti Marianne Tveit Haavind Kjersti Jørgensen Lovise Mæhle Ana Blatnik Joan Brunet Esther Darder Emma Tham Nicoline Hoogerbrugge Janet R. Vos
container_volume	16
class	RC254-282
format_se	Elektronische Aufsätze
author-letter	Linda A. J. Hendricks
doi_str_mv	10.3390/cancers16050953
author2-role	verfasserin
title_sort	lifestyle factors and breast cancer in females with pten hamartoma tumor syndrome (phts)
callnumber	RC254-282
title_auth	Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)
abstract	Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important.
abstractGer	Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important.
abstract_unstemmed	Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	5, p 953
title_short	Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)
url	https://doi.org/10.3390/cancers16050953 https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8 https://www.mdpi.com/2072-6694/16/5/953 https://doaj.org/toc/2072-6694
remote_bool	true
author2	Katja C. J. Verbeek Janneke H. M. Schuurs-Hoeijmakers Arjen R. Mensenkamp Hilde Brems Robin de Putter Violetta C. Anastasiadou Marie-Charlotte Villy Arne Jahn Verena Steinke-Lange Margherita Baldassarri Arvids Irmejs Mirjam M. de Jong Thera P. Links Edward M. Leter Daniëlle G. M. Bosch Hildegunn Høberg-Vetti Marianne Tveit Haavind Kjersti Jørgensen Lovise Mæhle Ana Blatnik Joan Brunet Esther Darder Emma Tham Nicoline Hoogerbrugge Janet R. Vos
author2Str	Katja C. J. Verbeek Janneke H. M. Schuurs-Hoeijmakers Arjen R. Mensenkamp Hilde Brems Robin de Putter Violetta C. Anastasiadou Marie-Charlotte Villy Arne Jahn Verena Steinke-Lange Margherita Baldassarri Arvids Irmejs Mirjam M. de Jong Thera P. Links Edward M. Leter Daniëlle G. M. Bosch Hildegunn Høberg-Vetti Marianne Tveit Haavind Kjersti Jørgensen Lovise Mæhle Ana Blatnik Joan Brunet Esther Darder Emma Tham Nicoline Hoogerbrugge Janet R. Vos
ppnlink	614095670
callnumber-subject	RC - Internal Medicine
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.3390/cancers16050953
callnumber-a	RC254-282
up_date	2024-07-03T19:29:54.813Z
_version_	1803587414728376320
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ091272653</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413232928.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240412s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/cancers16050953</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ091272653</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJfec7f542d3f149ddb920a8ada25386b8</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC254-282</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Linda A. J. Hendricks</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020–March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0–1 times/week physical activity than ≥2 times (OR<sub<total-adj</sub< = 0.9 (95%CI 0.3–2.6); consumed daily about 1.2–1.8 times more often ≥1 than 0–1 glasses of alcohol (OR<sub<total-adj</sub< = 1.2 (95%CI 0.4–4.0); OR<sub<non-breastcancer-index-adj</sub< = 1.8 (95%CI 0.4–6.9); were about 1.04–1.3 times more often smokers than non-smokers (OR<sub<total-adj</sub< = 1.04 (95%CI 0.4–2.8); OR<sub<non-breastcancer-index-adj</sub< = 1.3 (95%CI 0.4–4.2)); and overweight or obesity (72%) was about 1.02–1.3 times less common (OR<sub<total-adj</sub< = 0.98 (95%CI 0.4–2.6); OR<sub<non-breastcancer-index-adj</sub< = 0.8 (95%CI 0.3–2.7)). Similar associations between lifestyle and breast cancer are suggested for PHTS and the general population. Despite not being statistically significant, results are clinically relevant and suggest that awareness of the effects of lifestyle on patients’ breast cancer risk is important.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">alcohol drinking</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">body mass index</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">breast neoplasm</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">exercise</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">hamartoma syndrome</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">multiple</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neoplasms. Tumors. Oncology. Including cancer and carcinogens</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Katja C. J. Verbeek</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Janneke H. M. Schuurs-Hoeijmakers</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Arjen R. Mensenkamp</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hilde Brems</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Robin de Putter</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Violetta C. Anastasiadou</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marie-Charlotte Villy</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Arne Jahn</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Verena Steinke-Lange</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Margherita Baldassarri</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Arvids Irmejs</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mirjam M. de Jong</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Thera P. Links</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Edward M. Leter</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Daniëlle G. M. Bosch</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hildegunn Høberg-Vetti</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marianne Tveit Haavind</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kjersti Jørgensen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Lovise Mæhle</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ana Blatnik</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Joan Brunet</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Esther Darder</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Emma Tham</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nicoline Hoogerbrugge</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Janet R. Vos</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Cancers</subfield><subfield code="d">MDPI AG, 2010</subfield><subfield code="g">16(2024), 5, p 953</subfield><subfield code="w">(DE-627)614095670</subfield><subfield code="w">(DE-600)2527080-1</subfield><subfield code="x">20726694</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:16</subfield><subfield code="g">year:2024</subfield><subfield code="g">number:5, p 953</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/cancers16050953</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/fec7f542d3f149ddb920a8ada25386b8</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/2072-6694/16/5/953</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2072-6694</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">16</subfield><subfield code="j">2024</subfield><subfield code="e">5, p 953</subfield></datafield></record></collection>
score	7.3978424

Nicht das Richtige dabei?

Schreiben Sie uns!

Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS)

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?