Anticoagulant Rodenticides Poisonings in Humans and Animals – Short Review
Abstract Anticoagulant rodenticides (AR) are among the most commonly used rodent control pesticides. The current second-generation rodenticides in worldwide use are referred to as superwarfarins. These substances have relatively low toxicity to humans but significant toxicity to animals, including p...
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| Autor*in: |
Marcin Zawadzki [verfasserIn] Paweł Szpot Szpot [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Arabisch ; Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Arab Journal of Forensic Sciences & Forensic Medicine - Naif University Publishing House, 2017, 1(2019), 9, Seite 1260-1260 |
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| Übergeordnetes Werk: |
volume:1 ; year:2019 ; number:9 ; pages:1260-1260 |
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Link aufrufen |
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| DOI / URN: |
10.26735/16586794.2019.012 |
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| 520 | |a Abstract Anticoagulant rodenticides (AR) are among the most commonly used rodent control pesticides. The current second-generation rodenticides in worldwide use are referred to as superwarfarins. These substances have relatively low toxicity to humans but significant toxicity to animals, including pets. AR work at the level of hepatocytes by blocking the synthesis of plasma coagulation factors II, VII, IX, and X as well as proteins C, S, and Z, resulting in severe coagulation disorders predominant in the clinical picture. Deaths associated with AR poisoning are the result of haemorrhages into the gastrointestinal tract, peritoneal cavity, or intracranial cavities. Medico-legal diagnosis of AR poisonings is based on the clinical picture, autopsy, and histopathological and toxicological examinations. | ||
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10.26735/16586794.2019.012 doi (DE-627)DOAJ091292972 (DE-599)DOAJa0dcd8940f054c1fb6912d76a1046f2c DE-627 ger DE-627 rakwb ara eng R5-920 Marcin Zawadzki verfasserin aut Anticoagulant Rodenticides Poisonings in Humans and Animals – Short Review 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Anticoagulant rodenticides (AR) are among the most commonly used rodent control pesticides. The current second-generation rodenticides in worldwide use are referred to as superwarfarins. These substances have relatively low toxicity to humans but significant toxicity to animals, including pets. AR work at the level of hepatocytes by blocking the synthesis of plasma coagulation factors II, VII, IX, and X as well as proteins C, S, and Z, resulting in severe coagulation disorders predominant in the clinical picture. Deaths associated with AR poisoning are the result of haemorrhages into the gastrointestinal tract, peritoneal cavity, or intracranial cavities. Medico-legal diagnosis of AR poisonings is based on the clinical picture, autopsy, and histopathological and toxicological examinations. forensic science anticoagulants rodenticides poisoning humans. Medicine (General) Paweł Szpot Szpot verfasserin aut In Arab Journal of Forensic Sciences & Forensic Medicine Naif University Publishing House, 2017 1(2019), 9, Seite 1260-1260 (DE-627)1760595098 (DE-600)3068494-8 16586794 nnns volume:1 year:2019 number:9 pages:1260-1260 https://doi.org/10.26735/16586794.2019.012 kostenfrei https://doaj.org/article/a0dcd8940f054c1fb6912d76a1046f2c kostenfrei https://journals.nauss.edu.sa/index.php/AJFSFM/article/view/813 kostenfrei https://doaj.org/toc/1658-6786 Journal toc kostenfrei https://doaj.org/toc/1658-6794 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_22 GBV_ILN_2003 GBV_ILN_4305 AR 1 2019 9 1260-1260 |
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Abstract Anticoagulant rodenticides (AR) are among the most commonly used rodent control pesticides. The current second-generation rodenticides in worldwide use are referred to as superwarfarins. These substances have relatively low toxicity to humans but significant toxicity to animals, including pets. AR work at the level of hepatocytes by blocking the synthesis of plasma coagulation factors II, VII, IX, and X as well as proteins C, S, and Z, resulting in severe coagulation disorders predominant in the clinical picture. Deaths associated with AR poisoning are the result of haemorrhages into the gastrointestinal tract, peritoneal cavity, or intracranial cavities. Medico-legal diagnosis of AR poisonings is based on the clinical picture, autopsy, and histopathological and toxicological examinations. |
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Abstract Anticoagulant rodenticides (AR) are among the most commonly used rodent control pesticides. The current second-generation rodenticides in worldwide use are referred to as superwarfarins. These substances have relatively low toxicity to humans but significant toxicity to animals, including pets. AR work at the level of hepatocytes by blocking the synthesis of plasma coagulation factors II, VII, IX, and X as well as proteins C, S, and Z, resulting in severe coagulation disorders predominant in the clinical picture. Deaths associated with AR poisoning are the result of haemorrhages into the gastrointestinal tract, peritoneal cavity, or intracranial cavities. Medico-legal diagnosis of AR poisonings is based on the clinical picture, autopsy, and histopathological and toxicological examinations. |
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Abstract Anticoagulant rodenticides (AR) are among the most commonly used rodent control pesticides. The current second-generation rodenticides in worldwide use are referred to as superwarfarins. These substances have relatively low toxicity to humans but significant toxicity to animals, including pets. AR work at the level of hepatocytes by blocking the synthesis of plasma coagulation factors II, VII, IX, and X as well as proteins C, S, and Z, resulting in severe coagulation disorders predominant in the clinical picture. Deaths associated with AR poisoning are the result of haemorrhages into the gastrointestinal tract, peritoneal cavity, or intracranial cavities. Medico-legal diagnosis of AR poisonings is based on the clinical picture, autopsy, and histopathological and toxicological examinations. |
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Anticoagulant Rodenticides Poisonings in Humans and Animals – Short Review |
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https://doi.org/10.26735/16586794.2019.012 https://doaj.org/article/a0dcd8940f054c1fb6912d76a1046f2c https://journals.nauss.edu.sa/index.php/AJFSFM/article/view/813 https://doaj.org/toc/1658-6786 https://doaj.org/toc/1658-6794 |
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